Medical College of Wisconsin
CTSICores SearchResearch InformaticsREDCap

Mesh term GTP Cyclohydrolase

Browse to parent terms:
Aminohydrolases

Description

(GTP cyclohydrolase I) or GTP 7,8-8,9-dihydrolase (pyrophosphate-forming) (GTP cyclohydrolase II). An enzyme group that hydrolyzes the imidazole ring of GTP, releasing carbon-8 as formate. Two C-N bonds are hydrolyzed and the pentase unit is isomerized. This is the first step in the synthesis of folic acid from GTP. EC 3.5.4.16 (GTP cyclohydrolase I) and EC 3.5.4.25 (GTP cyclohydrolase II).



Search for this term in our Faculty Database



View this term at the NCBI website
jenkins-FCD Prod-468 69a93cef3257f26b866d455c1d2b2d0f28382f14