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Mesh term Philadelphia Chromosome

Browse to parent terms:
Chromosomes, Human, Pair 22
Chromosomes, Human, Pair 9
Translocation, Genetic

Description

An aberrant form of human CHROMOSOME 22 characterized by translocation of the distal end of chromosome 9 from 9q34, to the long arm of chromosome 22 at 22q11. It is present in the bone marrow cells of 80 to 90 per cent of patients with chronic myelocytic leukemia (LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE).



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jenkins-FCD Prod-486 e3098984f26de787f5ecab75090d0a28e7f4f7c0