Mesh term Quinidine
Browse to parent terms:Cinchona Alkaloids
Quinolines
Quinuclidines
Description
An optical isomer of quinine, extracted from the bark of the CHINCHONA tree and similar plant species. This alkaloid dampens the excitability of cardiac and skeletal muscles by blocking sodium and potassium currents across cellular membranes. It prolongs cellular ACTION POTENTIALS, and decreases automaticity. Quinidine also blocks muscarinic and alpha-adrenergic neurotransmission.Search for this term in our Faculty Database
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