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Mesh term Quinidine

Browse to parent terms:
Cinchona Alkaloids
Quinolines
Quinuclidines

Description

An optical isomer of quinine, extracted from the bark of the CHINCHONA tree and similar plant species. This alkaloid dampens the excitability of cardiac and skeletal muscles by blocking sodium and potassium currents across cellular membranes. It prolongs cellular ACTION POTENTIALS, and decreases automaticity. Quinidine also blocks muscarinic and alpha-adrenergic neurotransmission.



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jenkins-FCD Prod-480 9a4deaf152b0b06dd18151814fff2e18f6c05280