Medical College of Wisconsin
CTSICores SearchResearch InformaticsREDCap

Mesh term T-Lymphocytes, Cytotoxic

Browse to parent terms:
CD8-Positive T-Lymphocytes
Cytokine-Induced Killer Cells
T-Lymphocyte Subsets

Description

Immunized T-lymphocytes which can directly destroy appropriate target cells. These cytotoxic lymphocytes may be generated in vitro in mixed lymphocyte cultures (MLC), in vivo during a graft-versus-host (GVH) reaction, or after immunization with an allograft, tumor cell or virally transformed or chemically modified target cell. The lytic phenomenon is sometimes referred to as cell-mediated lympholysis (CML). These CD8-positive cells are distinct from NATURAL KILLER CELLS and NATURAL KILLER T-CELLS. There are two effector phenotypes: TC1 and TC2.



Search for this term in our Faculty Database



View this term at the NCBI website
jenkins-FCD Prod-482 91ad8a360b6da540234915ea01ff80e38bfdb40a