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Mesh term Giant Cell Arteritis

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Arteritis
Skin Diseases, Vascular
Vasculitis, Central Nervous System

Description

A systemic autoimmune disorder that typically affects medium and large ARTERIES, usually leading to occlusive granulomatous vasculitis with transmural infiltrate containing multinucleated GIANT CELLS. The TEMPORAL ARTERY is commonly involved. This disorder appears primarily in people over the age of 50. Symptoms include FEVER; FATIGUE; HEADACHE; visual impairment; pain in the jaw and tongue; and aggravation of pain by cold temperatures. (From Adams et al., Principles of Neurology, 6th ed)



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jenkins-FCD Prod-486 e3098984f26de787f5ecab75090d0a28e7f4f7c0