Medical College of Wisconsin
CTSICores SearchResearch InformaticsREDCap

Mesh term von Willebrand Factor

Browse to parent terms:
Blood Coagulation Factors


A high-molecular-weight plasma protein, produced by endothelial cells and megakaryocytes, that is part of the factor VIII/von Willebrand factor complex. The von Willebrand factor has receptors for collagen, platelets, and ristocetin activity as well as the immunologically distinct antigenic determinants. It functions in adhesion of platelets to collagen and hemostatic plug formation. The prolonged bleeding time in VON WILLEBRAND DISEASES is due to the deficiency of this factor.

Search for this term in our Faculty Database

View this term at the NCBI website