Mesh term Dideoxynucleosides
Browse to parent terms:Deoxyribonucleosides
Description
Nucleosides that have two hydroxy groups removed from the sugar moiety. The majority of these compounds have broad-spectrum antiretroviral activity due to their action as antimetabolites. The nucleosides are phosphorylated intracellularly to their 5'-triphosphates and act as chain-terminating inhibitors of viral reverse transcription.Browse to child terms:
Didanosine
Dideoxyadenosine
Stavudine
Zalcitabine
Zidovudine
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