Mesh term Histocompatibility Antigens Class I
Browse to parent terms:Histocompatibility Antigens
Membrane Glycoproteins
Description
Membrane glycoproteins consisting of an alpha subunit and a BETA 2-MICROGLOBULIN beta subunit. In humans, highly polymorphic genes on CHROMOSOME 6 encode the alpha subunits of class I antigens and play an important role in determining the serological specificity of the surface antigen. Class I antigens are found on most nucleated cells and are generally detected by their reactivity with alloantisera. These antigens are recognized during GRAFT REJECTION and restrict cell-mediated lysis of virus-infected cells.Browse to child terms:
H-2 Antigens
HLA-A Antigens
HLA-B Antigens
HLA-C Antigens
HLA-G Antigens
Hemochromatosis Protein
Histocompatibility Antigen H-2D
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