Mesh term Retinoblastoma Protein
Browse to parent terms:DNA-Binding Proteins
Nuclear Proteins
Phosphoproteins
Tumor Suppressor Proteins
Description
Product of the retinoblastoma tumor suppressor gene. It is a nuclear phosphoprotein hypothesized to normally act as an inhibitor of cell proliferation. Rb protein is absent in retinoblastoma cell lines. It also has been shown to form complexes with the adenovirus E1A protein, the SV40 T antigen, and the human papilloma virus E7 protein.Search for this term in our Faculty Database
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