Medical College of Wisconsin
CTSICores SearchResearch InformaticsREDCap

Mesh term Genes, myc

Browse to parent terms:
Proto-Oncogenes

Description

Family of retrovirus-associated DNA sequences (myc) originally isolated from an avian myelocytomatosis virus. The proto-oncogene myc (c-myc) codes for a nuclear protein which is involved in nucleic acid metabolism and in mediating the cellular response to growth factors. Truncation of the first exon, which appears to regulate c-myc expression, is crucial for tumorigenicity. The human c-myc gene is located at 8q24 on the long arm of chromosome 8.



Search for this term in our Faculty Database



View this term at the NCBI website
jenkins-FCD Prod-468 69a93cef3257f26b866d455c1d2b2d0f28382f14