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Mesh term Proto-Oncogene Proteins c-myc

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Basic Helix-Loop-Helix Transcription Factors
Nuclear Proteins
Proto-Oncogene Proteins


Basic helix-loop-helix transcription factors encoded by the c-myc genes. They are normally involved in nucleic acid metabolism and in mediating the cellular response to growth factors. Elevated and deregulated (constitutive) expression of c-myc proteins can cause tumorigenesis.

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