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Mesh term Proto-Oncogene Proteins c-fos

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Basic-Leucine Zipper Transcription Factors
Nuclear Proteins
Proto-Oncogene Proteins

Description

Cellular DNA-binding proteins encoded by the c-fos genes (GENES, FOS). They are involved in growth-related transcriptional control. c-fos combines with c-jun (PROTO-ONCOGENE PROTEINS C-JUN) to form a c-fos/c-jun heterodimer (TRANSCRIPTION FACTOR AP-1) that binds to the TRE (TPA-responsive element) in promoters of certain genes.



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jenkins-FCD Prod-486 e3098984f26de787f5ecab75090d0a28e7f4f7c0