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Mesh term Cross-Over Studies

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Epidemiologic Research Design

Description

Studies comparing two or more treatments or interventions in which the subjects or patients, upon completion of the course of one treatment, are switched to another. In the case of two treatments, A and B, half the subjects are randomly allocated to receive these in the order A, B and half to receive them in the order B, A. A criticism of this design is that effects of the first treatment may carry over into the period when the second is given. (Last, A Dictionary of Epidemiology, 2d ed)



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jenkins-FCD Prod-486 e3098984f26de787f5ecab75090d0a28e7f4f7c0