Mesh term Receptor, ErbB-2
Browse to parent terms:Biomarkers, Tumor
ErbB Receptors
Minor Histocompatibility Antigens
Proto-Oncogene Proteins
Description
A cell surface protein-tyrosine kinase receptor that is overexpressed in a variety of ADENOCARCINOMAS. It has extensive homology to and heterodimerizes with the EGF RECEPTOR, the ERBB-3 RECEPTOR, and the ERBB-4 RECEPTOR. Activation of the erbB-2 receptor occurs through heterodimer formation with a ligand-bound erbB receptor family member.Search for this term in our Faculty Database
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