Medical College of Wisconsin
CTSICores SearchResearch InformaticsREDCap

Mesh term Proliferating Cell Nuclear Antigen

Browse to parent terms:
Antigens, Nuclear
Biomarkers, Tumor
Nuclear Proteins

Description

Nuclear antigen with a role in DNA synthesis, DNA repair, and cell cycle progression. PCNA is required for the coordinated synthesis of both leading and lagging strands at the replication fork during DNA replication. PCNA expression correlates with the proliferation activity of several malignant and non-malignant cell types.



Search for this term in our Faculty Database



View this term at the NCBI website