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Mesh term CpG Islands

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GC Rich Sequence
Genome Components

Description

Areas of increased density of the dinucleotide sequence cytosine--phosphate diester--guanine. They form stretches of DNA several hundred to several thousand base pairs long. In humans there are about 45,000 CpG islands, mostly found at the 5' ends of genes. They are unmethylated except for those on the inactive X chromosome and some associated with imprinted genes.



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jenkins-FCD Prod-486 e3098984f26de787f5ecab75090d0a28e7f4f7c0