Mesh term Proto-Oncogene Proteins c-bcl-2
Browse to parent terms:Apoptosis Regulatory Proteins
Proto-Oncogene Proteins
Description
Membrane proteins encoded by the BCL-2 GENES and serving as potent inhibitors of cell death by APOPTOSIS. The proteins are found on mitochondrial, microsomal, and NUCLEAR MEMBRANE sites within many cell types. Overexpression of bcl-2 proteins, due to a translocation of the gene, is associated with follicular lymphoma.Browse to child terms:
BH3 Interacting Domain Death Agonist Protein
Myeloid Cell Leukemia Sequence 1 Protein
bcl-2 Homologous Antagonist-Killer Protein
bcl-2-Associated X Protein
bcl-Associated Death Protein
bcl-X Protein
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