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Mesh term Cytochrome P-450 CYP2D6

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Aryl Hydrocarbon Hydroxylases
Cytochrome P450 Family 2


A cytochrome P450 enzyme that catalyzes the hydroxylation of many drugs and environmental chemicals, such as DEBRISOQUINE; ADRENERGIC RECEPTOR ANTAGONISTS; and TRICYCLIC ANTIDEPRESSANTS. This enzyme is deficient in up to 10 percent of the Caucasian population.

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