Mesh term Anti-Glomerular Basement Membrane Disease
Browse to parent terms:Autoimmune Diseases
Glomerulonephritis
Lung Diseases, Interstitial
Description
An autoimmune disease of the KIDNEY and the LUNG. It is characterized by the presence of circulating autoantibodies targeting the epitopes in the non-collagenous domains of COLLAGEN TYPE IV in the basement membranes of kidney glomeruli (KIDNEY GLOMERULUS) and lung alveoli (PULMONARY ALVEOLI), and the subsequent destruction of these basement membranes. Clinical features include pulmonary alveolar hemorrhage and glomerulonephritis.Search for this term in our Faculty Database
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