Mesh term Proto-Oncogene Proteins c-rel
Browse to parent terms:DNA-Binding Proteins
Nuclear Proteins
Proto-Oncogene Proteins
Transcription Factors
Description
Cellular DNA-binding proteins encoded by the rel gene (GENES, REL). They are expressed predominately in hematopoietic cells and may play a role in lymphocyte differentiation. Rel frequently combines with other related proteins (NF-KAPPA B, I-kappa B, relA) to form heterodimers that regulate transcription. Rearrangement or overexpression of c-rel can cause tumorigenesis.Search for this term in our Faculty Database
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