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Mesh term Two-Hybrid System Techniques

Browse to parent terms:
Cloning, Molecular
Molecular Probe Techniques
Protein Interaction Mapping

Description

Screening techniques first developed in yeast to identify genes encoding interacting proteins. Variations are used to evaluate interplay between proteins and other molecules. Two-hybrid techniques refer to analysis for protein-protein interactions, one-hybrid for DNA-protein interactions, three-hybrid interactions for RNA-protein interactions or ligand-based interactions. Reverse n-hybrid techniques refer to analysis for mutations or other small molecules that dissociate known interactions.



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jenkins-FCD Prod-486 e3098984f26de787f5ecab75090d0a28e7f4f7c0