Medical College of Wisconsin
CTSICores SearchResearch InformaticsREDCap

Mesh term DNA Topoisomerase IV

Browse to parent terms:
Bacterial Proteins
DNA Topoisomerases, Type II

Description

A bacterial DNA topoisomerase II that catalyzes ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. Topoisomerase IV binds to DNA as a heterotetramer consisting 2 parC and 2 parE subunits. Topoisomerase IV is a decatenating enzyme that resolves interlinked daughter chromosomes following DNA replication.



Search for this term in our Faculty Database



View this term at the NCBI website