Mesh term RNA-Binding Protein EWS
Browse to parent terms:Calmodulin-Binding Proteins
Heterogeneous-Nuclear Ribonucleoproteins
Intracellular Signaling Peptides and Proteins
Proto-Oncogene Proteins
Description
A ubiquitous hnRNP protein that contains an RNA RECOGNITION MOTIF and C-terminal ranBP2-type zinc finger. It localizes to the CELL NUCLEUS and CYTOPLASM and is expressed as different isoforms in various tissues, interacting with CALMODULIN and TUMOR SUPPRESSOR PROTEIN P53 to negatively regulate cell growth. Translocations that result in the formation of fusion proteins containing parts of RNA-binding protein EWS are associated with EWING SARCOMA.Search for this term in our Faculty Database
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