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Mesh term Parathyroid Hormone-Related Protein

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Intercellular Signaling Peptides and Proteins
Peptide Hormones

Description

A ubiquitously expressed, secreted protein with bone resorption and renal calcium reabsorption activities that are similar to PARATHYROID HORMONE. It does not circulate in appreciable amounts in normal subjects, but rather exerts its biological actions locally. Overexpression of parathyroid hormone-related protein by tumor cells results in humoral calcemia of malignancy.



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