Mesh term Core Binding Factor Alpha 2 Subunit
Browse to parent terms:Core Binding Factor alpha Subunits
Description
A transcription factor that dimerizes with the cofactor CORE BINDING FACTOR BETA SUBUNIT to form core binding factor. It contains a highly conserved DNA-binding domain known as the runt domain. Runx1 is frequently mutated in human LEUKEMIAS.Search for this term in our Faculty Database
View this term at the NCBI website