Mesh term Proto-Oncogene Proteins c-akt
Browse to parent terms:Intracellular Signaling Peptides and Proteins
Protein-Serine-Threonine Kinases
Proto-Oncogene Proteins
Description
Protein-serine-threonine kinases that contain PLECKSTRIN HOMOLOGY DOMAINS and are activated by PHOSPHORYLATION in response to GROWTH FACTORS or INSULIN. They play a major role in cell metabolism, growth, and survival as a core component of SIGNAL TRANSDUCTION. Three isoforms have been described in mammalian cells.Search for this term in our Faculty Database
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