Mesh term rho-Associated Kinases
Browse to parent terms:Intracellular Signaling Peptides and Proteins
Protein-Serine-Threonine Kinases
Description
A group of intracellular-signaling serine threonine kinases that bind to RHO GTP-BINDING PROTEINS. They were originally found to mediate the effects of rhoA GTP-BINDING PROTEIN on the formation of STRESS FIBERS and FOCAL ADHESIONS. Rho-associated kinases have specificity for a variety of substrates including MYOSIN-LIGHT-CHAIN PHOSPHATASE and LIM KINASES.Search for this term in our Faculty Database
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