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Mesh term Programmed Cell Death 1 Receptor

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Antigens, Differentiation, T-Lymphocyte
Costimulatory and Inhibitory T-Cell Receptors


An inhibitory T-lymphocyte receptor that has specificity for CD274 ANTIGEN and PROGRAMMED CELL DEATH 1 LIGAND 2 PROTEIN. Signaling by the receptor limits T cell proliferation and INTERFERON GAMMA synthesis. The receptor also may play an essential role in the regulatory pathway that induces PERIPHERAL TOLERANCE.

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