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Mesh term Ataxia Telangiectasia Mutated Proteins

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Poly-ADP-Ribose Binding Proteins
Protein-Serine-Threonine Kinases


A group of PROTEIN-SERINE-THREONINE KINASES which activate critical signaling cascades in double strand breaks, APOPTOSIS, and GENOTOXIC STRESS such as ionizing ultraviolet A light, thereby acting as a DNA damage sensor. These proteins play a role in a wide range of signaling mechanisms in cell cycle control.

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