Medical College of Wisconsin
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Leukocyte hexokinase activity in aging and Alzheimer disease. Dementia 1995;6(4):200-4

Date

07/01/1995

Pubmed ID

7550599

DOI

10.1159/000106947

Scopus ID

2-s2.0-0029018903 (requires institutional sign-in at Scopus site)   4 Citations

Abstract

We determined the effects of clinical variables on hexokinase (HK) activity in leukocytes from Alzheimer's disease (AD) patients and controls. Age accounted for 51% of the variance in HK activity in the young and 23% in the old. Duration of illness in both familial and sporadic AD accounted for HK levels by 32 and 38%, respectively. Hexokinase activity increases with age and does not discriminate between familial and sporadic AD.

Author List

Antuono PG, Ravanelli-Meyer J, Nicholson K, Bloom AS

Authors

Piero G. Antuono MD Adjunct Professor in the Neurology department at Medical College of Wisconsin
Alan Bloom PhD, MA Emeritus Professor in the Pharmacology and Toxicology department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Adult
Age Factors
Aged
Aging
Alzheimer Disease
Energy Metabolism
Family
Hexokinase
Humans
Leukocytes
Middle Aged