Medical College of Wisconsin
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A microcomputer-based package for determination of regional and global cardiac function and coronary hemodynamics. J Pharmacol Methods 1984 Aug;12(1):59-67

Date

08/01/1984

Pubmed ID

6536815

DOI

10.1016/0160-5402(84)90007-x

Scopus ID

2-s2.0-0021248222 (requires institutional sign-in at Scopus site)   18 Citations

Abstract

A multichannel data acquisition package for reduction of systemic and coronary hemodynamic data that utilizes a personal microcomputer is described. The system provides a printout of heart rate, maximal rate of left ventricular pressure development (+dP/dt), maximal rate of ventricular relaxation (-dP/dt), absolute and normalized myocardial segment lengths, the degree of shortening of the segment over the cardiac cycle, systolic, diastolic, and mean coronary blood flow velocities, left ventricular systolic and end diastolic pressures, and systolic, diastolic, and mean aortic blood pressure from six channels of input data. Obtained values are precisely linked to the cardiac cycle. To illustrate the output of this system, data obtained by reading strip-chart records are compared to microcomputer-derived values in conscious, instrumented dogs.

Author List

Wilkison DM, Preuss KC, Warltier DC

Author

David C. Warltier PhD Emeritus Professor in the Anesthesiology department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Animals
Automation
Cardiology
Computers
Coronary Circulation
Dogs
Female
Hemodynamics
Isoproterenol
Male
Regional Blood Flow