Ultrasonic tissue characterization of normal and ischemic myocardium. Echocardiography 1990 Jan;7(1):11-9
Date
12/10/1989Pubmed ID
10149187DOI
10.1111/j.1540-8175.1990.tb00343.xScopus ID
2-s2.0-0025278033 (requires institutional sign-in at Scopus site) 1 CitationAbstract
Cardiac ultrasonic tissue characterization is designed to use the alterations in acoustic signals from the myocardium to differentiate normal from ischemic or infarcted tissue due to their characteristic backscatter attenuation. Various approaches such as use of a gray scale, color display, or quantitative image analysis have been used for tissue characterization, but all depend on subjective assessments and are not necessarily reproducible. The most promising method has been the use of "raw" radiofrequency signals and measure changes in the ultrasonic attenuation with an index of backscatter to distinguish normal from abnormal myocardium called "integrated backscatter" (IB). Various studies have demonstrated the changes in the ultrasonic backscatter with ischemia or infarction. In this review we summarize our experience with a research prototype instrument in tissue characterization and differentiation of normal, ischemic, infarcted, and post ischemic reperfused myocardium in anesthetized open chest dogs. Currently we are investigating the role of ultrasonic tissue characterization to estimate infarct size and plan to apply these observations to patients in order to detect viable myocardium and quantitate infarct size.
Author List
Sagar KB, Pelc LR, Saeian K, Rhyne TL, Wann LS, Warltier DCAuthor
David C. Warltier PhD Emeritus Professor in the Anesthesiology department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AnimalsCoronary Disease
Dogs
Echocardiography, Doppler
Evaluation Studies as Topic
Humans
Image Processing, Computer-Assisted
Myocardial Infarction
Myocardial Reperfusion Injury
