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Triple crystal disease: monosodium urate monohydrate, calcium pyrophosphate dihydrate, and basic calcium phosphate in a single joint. Ann Rheum Dis 1988 Oct;47(10):864-5

Date

10/01/1988

Pubmed ID

2848460

Pubmed Central ID

PMC1003617

DOI

10.1136/ard.47.10.864

Scopus ID

2-s2.0-0023788427 (requires institutional sign-in at Scopus site)   6 Citations

Abstract

A 49 year old man is described with a polyarticular arthritis. Synovial fluid aspirated from the knee joint showed monosodium urate monohydrate and calcium pyrophosphate dihydrate by polarised light microscopy. Additionally, diphosphonate binding and scanning electron microscopy with energy dispersive analysis showed that basic calcium phosphate crystals were also present. This appears to be the first report of three crystals occurring simultaneously in a single joint.

Author List

Halverson PB, Ryan LM

Authors

Paul Halverson MD Emeritus Professor in the Medicine department at Medical College of Wisconsin
Lawrence M. Ryan MD Emeritus Professor in the Medicine department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Arthritis
Calcium Phosphates
Calcium Pyrophosphate
Crystallization
Diphosphates
Humans
Knee Joint
Male
Middle Aged
Uric Acid