Faculty Collaboration Database

1. Ray A, Yang C, Stelloh C, Tutaj M, Liu P, Liu Y, Qiu Q, Auer PL, Lin CW, Widlansky ME, Geurts AM, Cowley AW Jr, Liang M, Kwitek AE, Greene AS, Rao S. Chromatin State Maps of Blood Pressure-Relevant Renal Segments Reveal Potential Regulatory Role for SNPs. Hypertension. 2024 Dec 26.

2. Li K, Smith ML, Blazier JC, Kochan KJ, Wood JMD, Howe K, Kwitek AE, Dwinell MR, Chen H, Ciosek JL, Masterson P, Murphy TD, Kalbfleisch TS, Doris PA. Construction and evaluation of a new rat reference genome assembly, GRCr8, from long reads and long-range scaffolding. Genome Res. 2024 Nov 20;34(11):2081-2093. PMCID: PMC11610589

3. Thareja SK, Yang X, Upama PB, Abdullah A, Torres SP, Cocroft LJ, Bubolz M, McGaughey K, Lou X, Kamaraju S, Ahamed SI, Madiraju P, Kwitek AE, Whittle J, Franco Z. Equitable community-based participatory research engagement with communities of color drives All of Us Wisconsin genomic research priorities. J Am Med Inform Assoc. 2024 Dec 01;31(12):2940-2951. PMCID: PMC11631115

4. Wildes MP, Fernando DG, Grobe CC, Reho JJ, Grobe JL, Kidambi S, Kindel TL, Kwitek AE, Segar JL, Williams JS, Morselli LL. Long-term Metabolic Dysfunction Programming in Female Mice by Serial Moderate Restriction of a High-fat High-sucrose Diet. Endocrinology. 2024 Aug 27;165(10). PMCID: PMC11408931

5. Kemmo Tsafack U, Ahn KW, Kwitek AE, Lin CW. Meta-Analytic Gene-Clustering Algorithm for Integrating Multi-Omics and Multi-Study Data. Bioengineering (Basel). 2024 Jun 08;11(6). PMCID: PMC11201102

6. Alliance of Genome Resources Consortium . Updates to the Alliance of Genome Resources central infrastructure. Genetics. 2024 May 07;227(1). PMCID: PMC11075569

7. de Jong TV, Pan Y, Rastas P, Munro D, Tutaj M, Akil H, Benner C, Chen D, Chitre AS, Chow W, Colonna V, Dalgard CL, Demos WM, Doris PA, Garrison E, Geurts AM, Gunturkun HM, Guryev V, Hourlier T, Howe K, Huang J, Kalbfleisch T, Kim P, Li L, Mahaffey S, Martin FJ, Mohammadi P, Ozel AB, Polesskaya O, Pravenec M, Prins P, Sebat J, Smith JR, Solberg Woods LC, Tabakoff B, Tracey A, Uliano-Silva M, Villani F, Wang H, Sharp BM, Telese F, Jiang Z, Saba L, Wang X, Murphy TD, Palmer AA, Kwitek AE, Dwinell MR, Williams RW, Li JZ, Chen H. A revamped rat reference genome improves the discovery of genetic diversity in laboratory rats. Cell Genom. 2024 Apr 10;4(4):100527. PMCID: PMC11019364

8. Morselli LL, Amjad R, James R, Kindel TL, Kwitek AE, Williams JS, Grobe JL, Kidambi S. Diet in Food Insecurity: A Mediator of Metabolic Health? J Endocr Soc. 2024 Apr 06;8(6):bvae062. PMCID: PMC11017326

9. Armoundas AA, Narayan SM, Arnett DK, Spector-Bagdady K, Bennett DA, Celi LA, Friedman PA, Gollob MH, Hall JL, Kwitek AE, Lett E, Menon BK, Sheehan KA, Al-Zaiti SS, American Heart Association Institute for Precision Cardiovascular Medicine; Council on Cardiovascular and Stroke Nursing; Council on Lifelong Congenital Heart Disease and Heart Health in the Young; Council on Cardiovascular Radiology and Intervention; Council on Hypertension; Council on the Kidney in Cardiovascular Disease; and Stroke Council. Use of Artificial Intelligence in Improving Outcomes in Heart Disease: A Scientific Statement From the American Heart Association. Circulation. 2024 Apr 02;149(14):e1028-e1050. PMCID: PMC11042786

10. Ritter ML, Wagner VA, Balapattabi K, Opichka MA, Lu KT, Wackman KK, Reho JJ, Keen HL, Kwitek AE, Morselli LL, Geurts AM, Sigmund CD, Grobe JL. Krüppel-like factor 4 in transcriptional control of the three unique isoforms of Agouti-related peptide in mice. Physiol Genomics. 2024 Mar 01;56(3):265-275. PMCID: PMC10866620

11. Opichka MA, Livergood MC, Balapattabi K, Ritter ML, Brozoski DT, Wackman KK, Lu KT, Kozak KN, Wells C, Fogo AB, Gibson-Corley KN, Kwitek AE, Sigmund CD, McIntosh JJ, Grobe JL. Mitochondrial-targeted antioxidant attenuates preeclampsia-like phenotypes induced by syncytiotrophoblast-specific Gαq signaling. Sci Adv. 2023 Dec;9(48):eadg8118. PMCID: PMC10691776

12. Wagner VA, Holl KL, Clark KC, Reho JJ, Lehmler HJ, Wang K, Grobe JL, Dwinell MR, Raff H, Kwitek AE. The Power of the Heterogeneous Stock Rat Founder Strains in Modeling Metabolic Disease. Endocrinology. 2023 Nov 02;164(12). PMCID: PMC10637104

13. Wagner VA, Deng G, Claflin KE, Ritter ML, Cui H, Nakagawa P, Sigmund CD, Morselli LL, Grobe JL, Kwitek AE. Cell-specific transcriptome changes in the hypothalamic arcuate nucleus in a mouse deoxycorticosterone acetate-salt model of hypertension. Front Cell Neurosci. 2023;17:1207350. PMCID: PMC10244568

14. Wagner VA, Holl KL, Clark KC, Reho JJ, Dwinell MR, Lehmler HJ, Raff H, Grobe JL, Kwitek AE. Genetic background in the rat affects endocrine and metabolic outcomes of bisphenol F exposure. Toxicol Sci. 2023 Jun 28;194(1):84-100. PMCID: PMC10306406

15. Kaldunski ML, Smith JR, Brodie KC, De Pons JL, Demos WM, Gibson AC, Hayman GT, Lamers L, Laulederkind SJF, Thorat K, Thota J, Tutaj MA, Tutaj M, Vedi M, Wang SJ, Zacher S, Dwinell MR, Kwitek AE. Rare disease research resources at the Rat Genome Database. Genetics. 2023 Aug 09;224(4). PMCID: PMC10411567

16. Vedi M, Smith JR, Thomas Hayman G, Tutaj M, Brodie KC, De Pons JL, Demos WM, Gibson AC, Kaldunski ML, Lamers L, Laulederkind SJF, Thota J, Thorat K, Tutaj MA, Wang SJ, Zacher S, Dwinell MR, Kwitek AE. 2022 updates to the Rat Genome Database: a Findable, Accessible, Interoperable, and Reusable (FAIR) resource. Genetics. 2023 May 04;224(1). PMCID: PMC10474928

17. Gene Ontology Consortium, Aleksander SA, Balhoff J, Carbon S, Cherry JM, Drabkin HJ, Ebert D, Feuermann M, Gaudet P, Harris NL, Hill DP, Lee R, Mi H, Moxon S, Mungall CJ, Muruganugan A, Mushayahama T, Sternberg PW, Thomas PD, Van Auken K, Ramsey J, Siegele DA, Chisholm RL, Fey P, Aspromonte MC, Nugnes MV, Quaglia F, Tosatto S, Giglio M, Nadendla S, Antonazzo G, Attrill H, Dos Santos G, Marygold S, Strelets V, Tabone CJ, Thurmond J, Zhou P, Ahmed SH, Asanitthong P, Luna Buitrago D, Erdol MN, Gage MC, Ali Kadhum M, Li KYC, Long M, Michalak A, Pesala A, Pritazahra A, Saverimuttu SCC, Su R, Thurlow KE, Lovering RC, Logie C, Oliferenko S, Blake J, Christie K, Corbani L, Dolan ME, Drabkin HJ, Hill DP, Ni L, Sitnikov D, Smith C, Cuzick A, Seager J, Cooper L, Elser J, Jaiswal P, Gupta P, Jaiswal P, Naithani S, Lera-Ramirez M, Rutherford K, Wood V, De Pons JL, Dwinell MR, Hayman GT, Kaldunski ML, Kwitek AE, Laulederkind SJF, Tutaj MA, Vedi M, Wang SJ, D'Eustachio P, Aimo L, Axelsen K, Bridge A, Hyka-Nouspikel N, Morgat A, Aleksander SA, Cherry JM, Engel SR, Karra K, Miyasato SR, Nash RS, Skrzypek MS, Weng S, Wong ED, Bakker E, Berardini TZ, Reiser L, Auchincloss A, Axelsen K, Argoud-Puy G, Blatter MC, Boutet E, Breuza L, Bridge A, Casals-Casas C, Coudert E, Estreicher A, Livia Famiglietti M, Feuermann M, Gos A, Gruaz-Gumowski N, Hulo C, Hyka-Nouspikel N, Jungo F, Le Mercier P, Lieberherr D, Masson P, Morgat A, Pedruzzi I, Pourcel L, Poux S, Rivoire C, Sundaram S, Bateman A, Bowler-Barnett E, Bye-A-Jee H, Denny P, Ignatchenko A, Ishtiaq R, Lock A, Lussi Y, Magrane M, Martin MJ, Orchard S, Raposo P, Speretta E, Tyagi N, Warner K, Zaru R, Diehl AD, Lee R, Chan J, Diamantakis S, Raciti D, Zarowiecki M, Fisher M, James-Zorn C, Ponferrada V, Zorn A, Ramachandran S, Ruzicka L, Westerfield M. The Gene Ontology knowledgebase in 2023. Genetics. 2023 May 04;224(1). PMCID: PMC10158837

18. McCarthy FM, Jones TEM, Kwitek AE, Smith CL, Vize PD, Westerfield M, Bruford EA. The case for standardizing gene nomenclature in vertebrates. Nature. 2023 Feb;614(7948):E31-E32. PMCID: PMC9931569

19. Wang SJ, Brodie KC, De Pons JL, Demos WM, Gibson AC, Hayman GT, Hill ML, Kaldunski ML, Lamers L, Laulederkind SJF, Nalabolu HS, Thota J, Thorat K, Tutaj MA, Tutaj M, Vedi M, Zacher S, Smith JR, Dwinell MR, Kwitek AE. Ontological Analysis of Coronavirus Associated Human Genes at the COVID-19 Disease Portal. Genes (Basel). 2022 Dec 07;13(12). PMCID: PMC9777590

20. Dursun C, Kwitek AE, Bozdag S. PhenoGeneRanker: Gene and Phenotype Prioritization Using Multiplex Heterogeneous Networks. IEEE/ACM Trans Comput Biol Bioinform. 2022;19(5):2950-2962. PMCID: PMC9704494

21. Clark KC, Wagner VA, Holl KL, Reho JJ, Tutaj M, Smith JR, Dwinell MR, Grobe JL, Kwitek AE. Body Composition and Metabolic Changes in a Lyon Hypertensive Congenic Rat and Identification of <i>Ercc6l2</i> as a Positional Candidate Gene. Front Genet. 2022;13:903971. PMCID: PMC9263446

22. Patil CN, Ritter ML, Wackman KK, Oliveira V, Balapattabi K, Grobe CC, Brozoski DT, Reho JJ, Nakagawa P, Mouradian GC Jr, Kriegel AJ, Kwitek AE, Hodges MR, Segar JL, Sigmund CD, Grobe JL. Cardiometabolic effects of DOCA-salt in male C57BL/6J mice are variably dependent on sodium and nonsodium components of diet. Am J Physiol Regul Integr Comp Physiol. 2022 Jun 01;322(6):R467-R485. PMCID: PMC9054347

23. Vedi M, Nalabolu HS, Lin CW, Hoffman MJ, Smith JR, Brodie K, De Pons JL, Demos WM, Gibson AC, Hayman GT, Hill ML, Kaldunski ML, Lamers L, Laulederkind SJF, Thorat K, Thota J, Tutaj M, Tutaj MA, Wang SJ, Zacher S, Dwinell MR, Kwitek AE. MOET: a web-based gene set enrichment tool at the Rat Genome Database for multiontology and multispecies analyses. Genetics. 2022 Apr 04;220(4). PMCID: PMC8982048

24. Alliance of Genome Resources Consortium. Harmonizing model organism data in the Alliance of Genome Resources. Genetics. 2022 Apr 04;220(4). PMCID: PMC8982023

25. Kaldunski ML, Smith JR, Hayman GT, Brodie K, De Pons JL, Demos WM, Gibson AC, Hill ML, Hoffman MJ, Lamers L, Laulederkind SJF, Nalabolu HS, Thorat K, Thota J, Tutaj M, Tutaj MA, Vedi M, Wang SJ, Zacher S, Dwinell MR, Kwitek AE. The Rat Genome Database (RGD) facilitates genomic and phenotypic data integration across multiple species for biomedical research. Mamm Genome. 2022 Mar;33(1):66-80. PMCID: PMC8570235

26. Reho JJ, Nakagawa P, Mouradian GC Jr, Grobe CC, Saravia FL, Burnett CML, Kwitek AE, Kirby JR, Segar JL, Hodges MR, Sigmund CD, Grobe JL. Methods for the Comprehensive <i>in vivo</i> Analysis of Energy Flux, Fluid Homeostasis, Blood Pressure, and Ventilatory Function in Rodents. Front Physiol. 2022;13:855054. PMCID: PMC8914175

27. Howe K, Dwinell M, Shimoyama M, Corton C, Betteridge E, Dove A, Quail MA, Smith M, Saba L, Williams RW, Chen H, Kwitek AE, McCarthy SA, Uliano-Silva M, Chow W, Tracey A, Torrance J, Sims Y, Challis R, Threlfall J, Blaxter M. The genome sequence of the Norway rat, <i>Rattus norvegicus</i> Berkenhout 1769. Wellcome Open Res. 2021;6:118. PMCID: PMC8495504

28. Wagner VA, Clark KC, Carrillo-Sáenz L, Holl KA, Velez-Bermudez M, Simonsen D, Grobe JL, Wang K, Thurman A, Solberg Woods LC, Lehmler HJ, Kwitek AE. Bisphenol F Exposure in Adolescent Heterogeneous Stock Rats Affects Growth and Adiposity. Toxicol Sci. 2021 May 27;181(2):246-261. PMCID: PMC8163043

29. Oliveira V, Kwitek AE, Sigmund CD, Morselli LL, Grobe JL. Recent Advances in Hypertension: Intersection of Metabolic and Blood Pressure Regulatory Circuits in the Central Nervous System. Hypertension. 2021 Apr;77(4):1061-1068. PMCID: PMC7990288

30. Dursun C, Smith JR, Hayman GT, Kwitek AE, Bozdag S. NECo: A node embedding algorithm for multiplex heterogeneous networks Proceedings - 2020 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2020. 16 December 2020:146-149.

31. Gene Ontology Consortium. The Gene Ontology resource: enriching a GOld mine. Nucleic Acids Res. 2021 Jan 08;49(D1):D325-D334. PMCID: PMC7779012

32. Berillo O, Ouerd S, Idris-Khodja N, Rehman A, Richer C, Sinnett D, Kwitek AE, Paradis P, Schiffrin EL. Chromosome 2 Fragment Substitutions in Dahl Salt-Sensitive Rats and RNA Sequencing Identified <i>Enpep</i> and <i>Hs2st1</i> as Vascular Inflammatory Modulators. Hypertension. 2021 Jan;77(1):178-189. PMCID: PMC7726001

33. Deng G, Morselli LL, Wagner VA, Balapattabi K, Sapouckey SA, Knudtson KL, Rahmouni K, Cui H, Sigmund CD, Kwitek AE, Grobe JL. Single-Nucleus RNA Sequencing of the Hypothalamic Arcuate Nucleus of C57BL/6J Mice After Prolonged Diet-Induced Obesity. Hypertension. 2020 Aug;76(2):589-597. PMCID: PMC7347451

34. Perschbacher KJ, Deng G, Sandgren JA, Walsh JW, Witcher PC, Sapouckey SA, Owens CE, Zhang SY, Scroggins SM, Pearson NA, Devor EJ, Sebag JA, Pierce GL, Fisher RA, Kwitek AE, Santillan DA, Gibson-Corley KN, Sigmund CD, Santillan MK, Grobe JL. Reduced mRNA Expression of RGS2 (Regulator of G Protein Signaling-2) in the Placenta Is Associated With Human Preeclampsia and Sufficient to Cause Features of the Disorder in Mice. Hypertension. 2020 Feb;75(2):569-579. PMCID: PMC7027931

35. Mansilla MA, Sompallae RR, Nishimura CJ, Kwitek AE, Kimble MJ, Freese ME, Campbell CA, Smith RJ, Thomas CP. Targeted broad-based genetic testing by next-generation sequencing informs diagnosis and facilitates management in patients with kidney diseases. Nephrol Dial Transplant. 2021 Jan 25;36(2):295-305. PMCID: PMC7834596

36. Smith JR, Hayman GT, Wang SJ, Laulederkind SJF, Hoffman MJ, Kaldunski ML, Tutaj M, Thota J, Nalabolu HS, Ellanki SLR, Tutaj MA, De Pons JL, Kwitek AE, Dwinell MR, Shimoyama ME. The Year of the Rat: The Rat Genome Database at 20: a multi-species knowledgebase and analysis platform. Nucleic Acids Res. 2020 Jan 08;48(D1):D731-D742. PMCID: PMC7145519

37. Stauss HM, Stangl H, Clark KC, Kwitek AE, Lira VA. Cervical vagal nerve stimulation impairs glucose tolerance and suppresses insulin release in conscious rats. Physiol Rep. 2018 Dec;6(24):e13953. PMCID: PMC6300710

38. Martín-Gálvez D, Dunoyer de Segonzac D, Ma MCJ, Kwitek AE, Thybert D, Flicek P. Genome variation and conserved regulation identify genomic regions responsible for strain specific phenotypes in rat. BMC Genomics. 2017 Dec 22;18(1):986. PMCID: PMC5741965

39. Ma MCJ, Pettus JM, Jakoubek JA, Traxler MG, Clark KC, Mennie AK, Kwitek AE. Contribution of independent and pleiotropic genetic effects in the metabolic syndrome in a hypertensive rat. PLoS One. 2017;12(8):e0182650. PMCID: PMC5549746

40. Thomas CP, Mansilla MA, Sompallae R, Mason SO, Nishimura CJ, Kimble MJ, Campbell CA, Kwitek AE, Darbro BW, Stewart ZA, Smith RJ. Screening of Living Kidney Donors for Genetic Diseases Using a Comprehensive Genetic Testing Strategy. Am J Transplant. 2017 Feb;17(2):401-410. PMCID: PMC5297870

41. Wang J, Ma MC, Mennie AK, Pettus JM, Xu Y, Lin L, Traxler MG, Jakoubek J, Atanur SS, Aitman TJ, Xing Y, Kwitek AE. Systems biology with high-throughput sequencing reveals genetic mechanisms underlying the metabolic syndrome in the Lyon hypertensive rat. Circ Cardiovasc Genet. 2015 Apr;8(2):316-26. PMCID: PMC4406788

42. Brownstein CA, Beggs AH, Homer N, Merriman B, Yu TW, Flannery KC, DeChene ET, Towne MC, Savage SK, Price EN, Holm IA, Luquette LJ, Lyon E, Majzoub J, Neupert P, McCallie D Jr, Szolovits P, Willard HF, Mendelsohn NJ, Temme R, Finkel RS, Yum SW, Medne L, Sunyaev SR, Adzhubey I, Cassa CA, de Bakker PI, Duzkale H, Dworzyński P, Fairbrother W, Francioli L, Funke BH, Giovanni MA, Handsaker RE, Lage K, Lebo MS, Lek M, Leshchiner I, MacArthur DG, McLaughlin HM, Murray MF, Pers TH, Polak PP, Raychaudhuri S, Rehm HL, Soemedi R, Stitziel NO, Vestecka S, Supper J, Gugenmus C, Klocke B, Hahn A, Schubach M, Menzel M, Biskup S, Freisinger P, Deng M, Braun M, Perner S, Smith RJ, Andorf JL, Huang J, Ryckman K, Sheffield VC, Stone EM, Bair T, Black-Ziegelbein EA, Braun TA, Darbro B, DeLuca AP, Kolbe DL, Scheetz TE, Shearer AE, Sompallae R, Wang K, Bassuk AG, Edens E, Mathews K, Moore SA, Shchelochkov OA, Trapane P, Bossler A, Campbell CA, Heusel JW, Kwitek A, Maga T, Panzer K, Wassink T, Van Daele D, Azaiez H, Booth K, Meyer N, Segal MM, Williams MS, Tromp G, White P, Corsmeier D, Fitzgerald-Butt S, Herman G, Lamb-Thrush D, McBride KL, Newsom D, Pierson CR, Rakowsky AT, Maver A, Lovrečić L, Palandačić A, Peterlin B, Torkamani A, Wedell A, Huss M, Alexeyenko A, Lindvall JM, Magnusson M, Nilsson D, Stranneheim H, Taylan F, Gilissen C, Hoischen A, van Bon B, Yntema H, Nelen M, Zhang W, Sager J, Zhang L, Blair K, Kural D, Cariaso M, Lennon GG, Javed A, Agrawal S, Ng PC, Sandhu KS, Krishna S, Veeramachaneni V, Isakov O, Halperin E, Friedman E, Shomron N, Glusman G, Roach JC, Caballero J, Cox HC, Mauldin D, Ament SA, Rowen L, Richards DR, San Lucas FA, Gonzalez-Garay ML, Caskey CT, Bai Y, Huang Y, Fang F, Zhang Y, Wang Z, Barrera J, Garcia-Lobo JM, González-Lamuño D, Llorca J, Rodriguez MC, Varela I, Reese MG, De La Vega FM, Kiruluta E, Cargill M, Hart RK, Sorenson JM, Lyon GJ, Stevenson DA, Bray BE, Moore BM, Eilbeck K, Yandell M, Zhao H, Hou L, Chen X, Yan X, Chen M, Li C, Yang C, Gunel M, Li P, Kong Y, Alexander AC, Albertyn ZI, Boycott KM, Bulman DE, Gordon PM, Innes AM, Knoppers BM, Majewski J, Marshall CR, Parboosingh JS, Sawyer SL, Samuels ME, Schwartzentruber J, Kohane IS, Margulies DM. An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge. Genome Biol. 2014 Mar 25;15(3):R53. PMCID: PMC4073084

43. Ma MC, Atanur SS, Aitman TJ, Kwitek AE. Genomic structure of nucleotide diversity among Lyon rat models of metabolic syndrome. BMC Genomics. 2014 Mar 14;15(1):197. PMCID: PMC4003853

44. Runge CL, Erbe CB, McNally MT, Van Dusen C, Friedland DR, Kwitek AE, Kerschner JE. A novel otoferlin splice-site mutation in siblings with auditory neuropathy spectrum disorder. Audiol Neurootol. 2013;18(6):374-82. PMCID: PMC3877672

45. Atanur SS, Diaz AG, Maratou K, Sarkis A, Rotival M, Game L, Tschannen MR, Kaisaki PJ, Otto GW, Ma MC, Keane TM, Hummel O, Saar K, Chen W, Guryev V, Gopalakrishnan K, Garrett MR, Joe B, Citterio L, Bianchi G, McBride M, Dominiczak A, Adams DJ, Serikawa T, Flicek P, Cuppen E, Hubner N, Petretto E, Gauguier D, Kwitek A, Jacob H, Aitman TJ. Genome sequencing reveals loci under artificial selection that underlie disease phenotypes in the laboratory rat. Cell. 2013 Aug 01;154(3):691-703. PMCID: PMC3732391

46. Park S, Lu KT, Liu X, Chatterjee TK, Rudich SM, Weintraub NL, Kwitek AE, Sigmund CD. Allele-specific expression of angiotensinogen in human subcutaneous adipose tissue. Hypertension. 2013 Jul;62(1):41-7. PMCID: PMC3718031

47. Moralejo DH, Fuller JM, Rutledge EA, Van Yserloo B, Ettinger RA, Jensen R, Osborne W, Kwitek A, Lernmark A. BB rat Gimap gene expression in sorted lymphoid T and B cells. Life Sci. 2011 Nov 07;89(19-20):748-54. PMCID: PMC3264544

48. Moralejo DH, Hansen CT, Treuting P, Hessner MJ, Fuller JM, Van Yserloo B, Jensen R, Osborne W, Kwitek AE, Lernmark A. Differential effects of leptin receptor mutation on male and female BBDR Gimap5-/Gimap5- spontaneously diabetic rats. Physiol Genomics. 2010 Mar 03;41(1):9-20. PMCID: PMC2841494

49. Gilibert S, Bataillard A, Nussberger J, Sassard J, Kwitek AE. Implication of chromosome 13 on hypertension and associated disorders in Lyon hypertensive rats. J Hypertens. 2009 Jun;27(6):1186-93. PMCID: PMC2915542

50. Rutledge EA, Fuller JM, Van Yserloo B, Moralejo DH, Ettinger RA, Gaur P, Hoehna JL, Peterson MR, Jensen R, Kwitek AE, Lernmark A. Sequence variation and expression of the Gimap gene family in the BB rat. Exp Diabetes Res. 2009;2009:835650. PMCID: PMC2676327

51. Fuller JM, Bogdani M, Tupling TD, Jensen RA, Pefley R, Manavi S, Cort L, Blankenhorn EP, Mordes JP, Lernmark A, Kwitek AE. Genetic dissection reveals diabetes loci proximal to the gimap5 lymphopenia gene. Physiol Genomics. 2009 Jun 10;38(1):89-97. PMCID: PMC2696149

52. Aneas I, Rodrigues MV, Pauletti BA, Silva GJ, Carmona R, Cardoso L, Kwitek AE, Jacob HJ, Soler JM, Krieger JE. Congenic strains provide evidence that four mapped loci in chromosomes 2, 4, and 16 influence hypertension in the SHR. Physiol Genomics. 2009 Mar 03;37(1):52-7.

53. Bilusić M, Moreno C, Barreto NE, Tschannen MR, Harris EL, Porteous WK, Thompson CM, Grigor MR, Weder A, Boerwinkle E, Hunt SC, Curb JD, Jacob HJ, Kwitek AE. Genetically hypertensive Brown Norway congenic rat strains suggest intermediate traits underlying genetic hypertension. Croat Med J. 2008 Oct;49(5):586-99. PMCID: PMC2582351

54. Schulteis RD, Chu H, Dai X, Chen Y, Edwards B, Haribhai D, Williams CB, Malarkannan S, Hessner MJ, Glisic-Milosavljevic S, Jana S, Kerschen EJ, Ghosh S, Wang D, Kwitek AE, Lernmark A, Gorski J, Weiler H. Impaired survival of peripheral T cells, disrupted NK/NKT cell development, and liver failure in mice lacking Gimap5. Blood. 2008 Dec 15;112(13):4905-14. PMCID: PMC2597598

55. Mattson DL, Dwinell MR, Greene AS, Kwitek AE, Roman RJ, Jacob HJ, Cowley AW Jr. Chromosome substitution reveals the genetic basis of Dahl salt-sensitive hypertension and renal disease. Am J Physiol Renal Physiol. 2008 Sep;295(3):F837-42. PMCID: PMC2536867

56. Shimoyama M, Petri V, Pasko D, Bromberg S, Wu W, Chen J, Nenasheva N, Kwitek A, Twigger S, Jacob H. Using multiple ontologies to integrate complex biological data. Comp Funct Genomics. 2005;6(7-8):373-8. PMCID: PMC2447497

57. Aitman TJ, Critser JK, Cuppen E, Dominiczak A, Fernandez-Suarez XM, Flint J, Gauguier D, Geurts AM, Gould M, Harris PC, Holmdahl R, Hubner N, Izsvák Z, Jacob HJ, Kuramoto T, Kwitek AE, Marrone A, Mashimo T, Moreno C, Mullins J, Mullins L, Olsson T, Pravenec M, Riley L, Saar K, Serikawa T, Shull JD, Szpirer C, Twigger SN, Voigt B, Worley K. Progress and prospects in rat genetics: a community view. Nat Genet. 2008 May;40(5):516-22.

58. Liang M, Lee NH, Wang H, Greene AS, Kwitek AE, Kaldunski ML, Luu TV, Frank BC, Bugenhagen S, Jacob HJ, Cowley AW Jr. Molecular networks in Dahl salt-sensitive hypertension based on transcriptome analysis of a panel of consomic rats. Physiol Genomics. 2008 Jun 12;34(1):54-64.

59. Gilibert S, Kwitek AE, Hubner N, Tschannen M, Jacob HJ, Sassard J, Bataillard A. Effects of chromosome 17 on features of the metabolic syndrome in the Lyon hypertensive rat. Physiol Genomics. 2008 Apr 22;33(2):212-7.

60. Mattson DL, Dwinell MR, Greene AS, Kwitek AE, Roman RJ, Cowley AW Jr, Jacob HJ. Chromosomal mapping of the genetic basis of hypertension and renal disease in FHH rats. Am J Physiol Renal Physiol. 2007 Dec;293(6):F1905-14.

61. Baessler A, Fischer M, Mayer B, Koehler M, Wiedmann S, Stark K, Doering A, Erdmann J, Riegger G, Schunkert H, Kwitek AE, Hengstenberg C. Epistatic interaction between haplotypes of the ghrelin ligand and receptor genes influence susceptibility to myocardial infarction and coronary artery disease. Hum Mol Genet. 2007 Apr 15;16(8):887-99.

62. Fuller JM, Kwitek AE, Hawkins TJ, Moralejo DH, Lu W, Tupling TD, MacMurray AJ, Borchardt G, Hasinoff M, Lernmark A. Erratum: Introgression of F344 rat genomic DNA on BB rat chromosome 4 generates diabetes-resistant lymphopenic BB rats (Diabetes (2006) 55 (3351-3357)) Diabetes. February 2007;56(2):549.

63. Twigger SN, Shimoyama M, Bromberg S, Kwitek AE, Jacob HJ, RGD Team. The Rat Genome Database, update 2007--easing the path from disease to data and back again. Nucleic Acids Res. 2007 Jan;35(Database issue):D658-62. PMCID: PMC1761441

64. Fuller JM, Kwitek AE, Hawkins TJ, Moralejo DH, Lu W, Tupling TD, Macmurray AJ, Borchardt G, Hasinoff M, Lernmark A. Introgression of F344 rat genomic DNA on BB rat chromosome 4 generates diabetes-resistant lymphopenic BB rats. Diabetes. 2006 Dec;55(12):3351-7.

65. Geoffrey R, Jia S, Kwitek AE, Woodliff J, Ghosh S, Lernmark A, Wang X, Hessner MJ. Evidence of a functional role for mast cells in the development of type 1 diabetes mellitus in the BioBreeding rat. J Immunol. 2006 Nov 15;177(10):7275-86.

66. Schlick NE, Jensen-Seaman MI, Orlebeke K, Kwitek AE, Jacob HJ, Lazar J. Sequence analysis of the complete mitochondrial DNA in 10 commonly used inbred rat strains. Am J Physiol Cell Physiol. 2006 Dec;291(6):C1183-92.

67. Kunert MP, Drenjancevic-Peric I, Dwinell MR, Lombard JH, Cowley AW Jr, Greene AS, Kwitek AE, Jacob HJ. Consomic strategies to localize genomic regions related to vascular reactivity in the Dahl salt-sensitive rat. Physiol Genomics. 2006 Aug 16;26(3):218-25.

68. Baessler A, Kwitek AE, Fischer M, Koehler M, Reinhard W, Erdmann J, Riegger G, Doering A, Schunkert H, Hengstenberg C. Association of the Ghrelin receptor gene region with left ventricular hypertrophy in the general population: results of the MONICA/KORA Augsburg Echocardiographic Substudy. Hypertension. 2006 May;47(5):920-7.

69. Kwitek AE, Jacob HJ, Baker JE, Dwinell MR, Forster HV, Greene AS, Kunert MP, Lombard JH, Mattson DL, Pritchard KA Jr, Roman RJ, Tonellato PJ, Cowley AW Jr. BN phenome: detailed characterization of the cardiovascular, renal, and pulmonary systems of the sequenced rat. Physiol Genomics. 2006 Apr 13;25(2):303-13.

70. Malek RL, Wang HY, Kwitek AE, Greene AS, Bhagabati N, Borchardt G, Cahill L, Currier T, Frank B, Fu X, Hasinoff M, Howe E, Letwin N, Luu TV, Saeed A, Sajadi H, Salzberg SL, Sultana R, Thiagarajan M, Tsai J, Veratti K, White J, Quackenbush J, Jacob HJ, Lee NH. Physiogenomic resources for rat models of heart, lung and blood disorders. Nat Genet. 2006 Feb;38(2):234-9.

71. Roman RJ, Hoagland KM, Lopez B, Kwitek AE, Garrett MR, Rapp JP, Lazar J, Jacob HJ, Sarkis A. Characterization of blood pressure and renal function in chromosome 5 congenic strains of Dahl S rats. Am J Physiol Renal Physiol. 2006 Jun;290(6):F1463-71.

72. Di Nicolantonio R, Kostka V, Kwitek A, Jacob H, Thomas WG, Harrap SB. Fine mapping of Lvm1: a quantitative trait locus controlling heart size independently of blood pressure. Pulm Pharmacol Ther. 2006;19(1):70-3.

73. Twigger SN, Pasko D, Nie J, Shimoyama M, Bromberg S, Campbell D, Chen J, dela Cruz N, Fan C, Foote C, Harris G, Hickmann B, Ji Y, Jin W, Li D, Mathis J, Nenasheva N, Nigam R, Petri V, Reilly D, Ruotti V, Schauberger E, Seiler K, Slyper R, Smith J, Wang W, Wu W, Zhao L, Zuniga-Meyer A, Tonellato PJ, Kwitek AE, Jacob HJ. Tools and strategies for physiological genomics: the Rat Genome Database. Physiol Genomics. 2005 Oct 17;23(2):246-56. PMCID: PMC4505745

74. Roche JP, Wackym PA, Cioffi JA, Kwitek AE, Erbe CB, Popper P. In silico analysis of 2085 clones from a normalized rat vestibular periphery 3' cDNA library. Audiol Neurootol. 2005;10(6):310-22. PMCID: PMC1421512

75. Baessler A, Hasinoff MJ, Fischer M, Reinhard W, Sonnenberg GE, Olivier M, Erdmann J, Schunkert H, Doering A, Jacob HJ, Comuzzie AG, Kissebah AH, Kwitek AE. Genetic linkage and association of the growth hormone secretagogue receptor (ghrelin receptor) gene in human obesity. Diabetes. 2005 Jan;54(1):259-67. PMCID: PMC2793077

76. de la Cruz N, Bromberg S, Pasko D, Shimoyama M, Twigger S, Chen J, Chen CF, Fan C, Foote C, Gopinath GR, Harris G, Hughes A, Ji Y, Jin W, Li D, Mathis J, Nenasheva N, Nie J, Nigam R, Petri V, Reilly D, Wang W, Wu W, Zuniga-Meyer A, Zhao L, Kwitek A, Tonellato P, Jacob H. The Rat Genome Database (RGD): developments towards a phenome database. Nucleic Acids Res. 2005 Jan 01;33(Database issue):D485-91. PMCID: PMC540004

77. Bilusic M, Bataillard A, Tschannen MR, Gao L, Barreto NE, Vincent M, Wang T, Jacob HJ, Sassard J, Kwitek AE. Mapping the genetic determinants of hypertension, metabolic diseases, and related phenotypes in the lyon hypertensive rat. Hypertension. 2004 Nov;44(5):695-701.

78. Michalkiewicz M, Michalkiewicz T, Ettinger RA, Rutledge EA, Fuller JM, Moralejo DH, Van Yserloo B, MacMurray AJ, Kwitek AE, Jacob HJ, Lander ES, Lernmark A. Transgenic rescue demonstrates involvement of the Ian5 gene in T cell development in the rat. Physiol Genomics. 2004 Oct 04;19(2):228-32.

79. Kwitek AE, Gullings-Handley J, Yu J, Carlos DC, Orlebeke K, Nie J, Eckert J, Lemke A, Andrae JW, Bromberg S, Pasko D, Chen D, Scheetz TE, Casavant TL, Soares MB, Sheffield VC, Tonellato PJ, Jacob HJ. High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat genome sequence. Genome Res. 2004 Apr;14(4):750-7. PMCID: PMC383322

80. Twigger SN, Nie J, Ruotti V, Yu J, Chen D, Li D, Mathis J, Narayanasamy V, Gopinath GR, Pasko D, Shimoyama M, De La Cruz N, Bromberg S, Kwitek AE, Jacob HJ, Tonellato PJ. Integrative genomics: in silico coupling of rat physiology and complex traits with mouse and human data. Genome Res. 2004 Apr;14(4):651-60. PMCID: PMC383309

81. Gibbs RA, Weinstock GM, Metzker ML, Muzny DM, Sodergren EJ, Scherer S, Scott G, Steffen D, Worley KC, Burch PE, Okwuonu G, Hines S, Lewis L, DeRamo C, Delgado O, Dugan-Rocha S, Miner G, Morgan M, Hawes A, Gill R, Celera, Holt RA, Adams MD, Amanatides PG, Baden-Tillson H, Barnstead M, Chin S, Evans CA, Ferriera S, Fosler C, Glodek A, Gu Z, Jennings D, Kraft CL, Nguyen T, Pfannkoch CM, Sitter C, Sutton GG, Venter JC, Woodage T, Smith D, Lee HM, Gustafson E, Cahill P, Kana A, Doucette-Stamm L, Weinstock K, Fechtel K, Weiss RB, Dunn DM, Green ED, Blakesley RW, Bouffard GG, De Jong PJ, Osoegawa K, Zhu B, Marra M, Schein J, Bosdet I, Fjell C, Jones S, Krzywinski M, Mathewson C, Siddiqui A, Wye N, McPherson J, Zhao S, Fraser CM, Shetty J, Shatsman S, Geer K, Chen Y, Abramzon S, Nierman WC, Havlak PH, Chen R, Durbin KJ, Simons R, Ren Y, Song XZ, Li B, Liu Y, Qin X, Cawley S, Worley KC, Cooney AJ, D'Souza LM, Martin K, Wu JQ, Gonzalez-Garay ML, Jackson AR, Kalafus KJ, McLeod MP, Milosavljevic A, Virk D, Volkov A, Wheeler DA, Zhang Z, Bailey JA, Eichler EE, Tuzun E, Birney E, Mongin E, Ureta-Vidal A, Woodwark C, Zdobnov E, Bork P, Suyama M, Torrents D, Alexandersson M, Trask BJ, Young JM, Huang H, Wang H, Xing H, Daniels S, Gietzen D, Schmidt J, Stevens K, Vitt U, Wingrove J, Camara F, Mar Albà M, Abril JF, Guigo R, Smit A, Dubchak I, Rubin EM, Couronne O, Poliakov A, Hübner N, Ganten D, Goesele C, Hummel O, Kreitler T, Lee YA, Monti J, Schulz H, Zimdahl H, Himmelbauer H, Lehrach H, Jacob HJ, Bromberg S, Gullings-Handley J, Jensen-Seaman MI, Kwitek AE, Lazar J, Pasko D, Tonellato PJ, Twigger S, Ponting CP, Duarte JM, Rice S, Goodstadt L, Beatson SA, Emes RD, Winter EE, Webber C, Brandt P, Nyakatura G, Adetobi M, Chiaromonte F, Elnitski L, Eswara P, Hardison RC, Hou M, Kolbe D, Makova K, Miller W, Nekrutenko A, Riemer C, Schwartz S, Taylor J, Yang S, Zhang Y, Lindpaintner K, Andrews TD, Caccamo M, Clamp M, Clarke L, Curwen V, Durbin R, Eyras E, Searle SM, Cooper GM, Batzoglou S, Brudno M, Sidow A, Stone EA, Venter JC, Payseur BA, Bourque G, López-Otín C, Puente XS, Chakrabarti K, Chatterji S, Dewey C, Pachter L, Bray N, Yap VB, Caspi A, Tesler G, Pevzner PA, Haussler D, Roskin KM, Baertsch R, Clawson H, Furey TS, Hinrichs AS, Karolchik D, Kent WJ, Rosenbloom KR, Trumbower H, Weirauch M, Cooper DN, Stenson PD, Ma B, Brent M, Arumugam M, Shteynberg D, Copley RR, Taylor MS, Riethman H, Mudunuri U, Peterson J, Guyer M, Felsenfeld A, Old S, Mockrin S, Collins F, Rat Genome Sequencing Project Consortium. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Nature. 2004 Apr 01;428(6982):493-521.

82. Sonnenberg GE, Krakower GR, Martin LJ, Olivier M, Kwitek AE, Comuzzie AG, Blangero J, Kissebah AH. Genetic determinants of obesity-related lipid traits. J Lipid Res. 2004 Apr;45(4):610-5. PMCID: PMC2771634

83. Cioffi JA, Erbe CB, Raphael R, Kwitek AE, Tiwari UK, Jacob HJ, Popper P, Wackym PA. Expression of G-protein alpha subunit genes in the vestibular periphery of Rattus norvegicus and their chromosomal mapping. Acta Otolaryngol. 2003 Dec;123(9):1027-34.

84. Moralejo DH, Park HA, Speros SJ, MacMurray AJ, Kwitek AE, Jacob HJ, Lander ES, Lernmark A. Genetic dissection of lymphopenia from autoimmunity by introgression of mutated Ian5 gene onto the F344 rat. J Autoimmun. 2003 Dec;21(4):315-24. PMCID: PMC7126882

85. Roman RJ, Cowley AW Jr, Greene A, Kwitek AE, Tonellato PJ, Jacob HJ. Consomic rats for the identification of genes and pathways underlying cardiovascular disease. Cold Spring Harb Symp Quant Biol. 2002;67:309-15.

86. Wang HY, Malek RL, Kwitek AE, Greene AS, Luu TV, Behbahani B, Frank B, Quackenbush J, Lee NH. Assessing unmodified 70-mer oligonucleotide probe performance on glass-slide microarrays. Genome Biol. 2003;4(1):R5. PMCID: PMC151289

87. Tseng J, Erbe CB, Kwitek AE, Jacob HJ, Popper P, Wackym PA. Radiation hybrid mapping of five muscarinic acetylcholine receptor subtype genes in Rattus norvegicus. Hear Res. 2002 Dec;174(1-2):86-92.

88. MacMurray AJ, Moralejo DH, Kwitek AE, Rutledge EA, Van Yserloo B, Gohlke P, Speros SJ, Snyder B, Schaefer J, Bieg S, Jiang J, Ettinger RA, Fuller J, Daniels TL, Pettersson A, Orlebeke K, Birren B, Jacob HJ, Lander ES, Lernmark A. Lymphopenia in the BB rat model of type 1 diabetes is due to a mutation in a novel immune-associated nucleotide (Ian)-related gene. Genome Res. 2002 Jul;12(7):1029-39. PMCID: PMC186618

89. Wallace CA, Ali S, Glazier AM, Norsworthy PJ, Carlos DC, Scott J, Freeman TC, Stanton LW, Kwitek AE, Aitman TJ. Radiation hybrid mapping of 70 rat genes from a data set of differentially expressed genes. Mamm Genome. 2002 Apr;13(4):194-7.

90. Twigger S, Lu J, Shimoyama M, Chen D, Pasko D, Long H, Ginster J, Chen CF, Nigam R, Kwitek A, Eppig J, Maltais L, Maglott D, Schuler G, Jacob H, Tonellato PJ. Rat Genome Database (RGD): mapping disease onto the genome. Nucleic Acids Res. 2002 Jan 01;30(1):125-8. PMCID: PMC99132

91. Kwitek AE, Tonellato PJ, Chen D, Gullings-Handley J, Cheng YS, Twigger S, Scheetz TE, Casavant TL, Stoll M, Nobrega MA, Shiozawa M, Soares MB, Sheffield VC, Jacob HJ. Automated construction of high-density comparative maps between rat, human, and mouse. Genome Res. 2001 Nov;11(11):1935-43. PMCID: PMC311144

92. Comuzzie AG, Funahashi T, Sonnenberg G, Martin LJ, Jacob HJ, Black AE, Maas D, Takahashi M, Kihara S, Tanaka S, Matsuzawa Y, Blangero J, Cohen D, Kissebah A. The genetic basis of plasma variation in adiponectin, a global endophenotype for obesity and the metabolic syndrome. J Clin Endocrinol Metab. 2001 Sep;86(9):4321-5.

93. Tseng J, Kwitek-Black AE, Erbe CB, Popper P, Jacob HJ, Wackym PA. Radiation hybrid mapping of 11 alpha and beta nicotinic acetylcholine receptor genes in Rattus norvegicus. Brain Res Mol Brain Res. 2001 Jul 13;91(1-2):169-73.

94. Nishimura DY, Searby CC, Carmi R, Elbedour K, Van Maldergem L, Fulton AB, Lam BL, Powell BR, Swiderski RE, Bugge KE, Haider NB, Kwitek-Black AE, Ying L, Duhl DM, Gorman SW, Heon E, Iannaccone A, Bonneau D, Biesecker LG, Jacobson SG, Stone EM, Sheffield VC. Positional cloning of a novel gene on chromosome 16q causing Bardet-Biedl syndrome (BBS2). Hum Mol Genet. 2001 Apr 01;10(8):865-74.

95. Scheetz TE, Raymond MR, Nishimura DY, McClain A, Roberts C, Birkett C, Gardiner J, Zhang J, Butters N, Sun C, Kwitek-Black A, Jacob H, Casavant TL, Soares MB, Sheffield VC. Generation of a high-density rat EST map. Genome Res. 2001 Mar;11(3):497-502. PMCID: PMC311028

96. Ou H, Haendeler J, Aebly MR, Kelly LA, Cholewa BC, Koike G, Kwitek-Black A, Jacob HJ, Berk BC, Miano JM. Retinoic acid-induced tissue transglutaminase and apoptosis in vascular smooth muscle cells. Circ Res. 2000 Nov 10;87(10):881-7.

97. Gösele C, Hong L, Kreitler T, Rossmann M, Hieke B, Gross U, Kramer M, Himmelbauer H, Bihoreau MT, Kwitek-Black AE, Twigger S, Tonellato PJ, Jacob HJ, Schalkwyk LC, Lindpaintner K, Ganten D, Lehrach H, Knoblauch M. High-throughput scanning of the rat genome using interspersed repetitive sequence-PCR markers. Genomics. 2000 Nov 01;69(3):287-94.

98. Stoll M, Kwitek-Black AE, Cowley AW Jr, Harris EL, Harrap SB, Krieger JE, Printz MP, Provoost AP, Sassard J, Jacob HJ. New target regions for human hypertension via comparative genomics. Genome Res. 2000 Apr;10(4):473-82. PMCID: PMC310887

99. Glickman M, Malek RL, Kwitek-Black AE, Jacob HJ, Lee NH. Molecular cloning, tissue-specific expression, and chromosomal localization of a novel nerve growth factor-regulated G-protein- coupled receptor, nrg-1. Mol Cell Neurosci. 1999 Aug;14(2):141-52.

100. Steen RG, Kwitek-Black AE, Glenn C, Gullings-Handley J, Van Etten W, Atkinson OS, Appel D, Twigger S, Muir M, Mull T, Granados M, Kissebah M, Russo K, Crane R, Popp M, Peden M, Matise T, Brown DM, Lu J, Kingsmore S, Tonellato PJ, Rozen S, Slonim D, Young P, Jacob HJ. A high-density integrated genetic linkage and radiation hybrid map of the laboratory rat. Genome Res. 1999 Jun;9(6):AP1-8, insert.

101. Bonné-Tamir B, Nystuen A, Seroussi E, Kalinsky H, Kwitek-Black AE, Korostishevsky M, Adato A, Sheffield VC. Usher syndrome in the Samaritans: strengths and limitations of using inbred isolated populations to identify genes causing recessive disorders. Am J Phys Anthropol. 1997 Oct;104(2):193-200.

102. Kwitek-Black AE, Krizman D, Carmi R, Doggett N, Stone EM, Sheffield VC. Fine-mapping of Bardet-Biedl syndrome locus on chromosome 16 Investigative Ophthalmology and Visual Science. 15 February 1996;37(3).

103. Carmi R, Rokhlina T, Kwitek-Black AE, Elbedour K, Nishimura D, Stone EM, Sheffield VC. Use of a DNA pooling strategy to identify a human obesity syndrome locus on chromosome 15. Hum Mol Genet. 1995 Jan;4(1):9-13.

104. Sheffield VC, Carmi R, Kwitek-Black A, Rokhlina T, Nishimura D, Duyk GM, Elbedour K, Sunden SL, Stone EM. Identification of a Bardet-Biedl syndrome locus on chromosome 3 and evaluation of an efficient approach to homozygosity mapping. Hum Mol Genet. 1994 Aug;3(8):1331-5.

105. Kwitek-Black AE, Carmi R, Duyk GM, Buetow KH, Elbedour K, Parvari R, Yandava CN, Stone EM, Sheffield VC. Linkage of Bardet-Biedl syndrome to chromosome 16q and evidence for non-allelic genetic heterogeneity. Nat Genet. 1993 Dec;5(4):392-6.

106. Sheffield VC, Beck JS, Kwitek AE, Sandstrom DW, Stone EM. The sensitivity of single-strand conformation polymorphism analysis for the detection of single base substitutions. Genomics. 1993 May;16(2):325-32.

107. Johnson AT, Drack AV, Kwitek AE, Cannon RL, Stone EM, Alward WL. Clinical features and linkage analysis of a family with autosomal dominant juvenile glaucoma. Ophthalmology. 1993 Apr;100(4):524-9.

108. Beck JS, Kwitek AE, Cogen PH, Metzger AK, Duyk GM, Sheffield VC. A denaturing gradient gel electrophoresis assay for sensitive detection of p53 mutations. Hum Genet. 1993 Mar;91(1):25-30.

109. Murray JC, Bennett SR, Kwitek AE, Small KW, Schinzel A, Alward WL, Weber JL, Bell GI, Buetow KH. Linkage of Rieger syndrome to the region of the epidermal growth factor gene on chromosome 4. Nat Genet. 1992 Sep;2(1):46-9.

110. Weber JL, Polymeropoulos MH, May PE, Kwitek AE, Xiao H, McPherson JD, Wasmuth JJ. Mapping of human chromosome 5 microsatellite DNA polymorphisms. Genomics. 1991 Nov;11(3):695-700.

111. Petersen MB, Weber JL, Slaugenhaupt SA, Kwitek AE, McInnis MG, Chakravarti A, Antonarakis SE. Linkage mapping of D21S171 to the distal long arm of human chromosome 21 using a polymorphic (AC)n dinucleotide repeat. Hum Genet. 1991 Aug;87(4):401-4.

112. Weber JL, Kwitek AE, May PE, Zoghbi HY. Dinucleotide repeat polymorphism at the D6S105 locus. Nucleic Acids Res. 1991 Feb 25;19(4):968. PMCID: PMC333759

113. Lewis JG, Weber JL, Petersen MB, Slaugenhaupt SA, Kwitek A, May PE, Warren AC, Chakravarti A, Antonarakis SE. Linkage mapping of the highly informative DNA marker D21S156 to human chromosome 21 using a polymorphic GT dinucleotide repeat. Genomics. 1990 Oct;8(2):400-2.

114. Weber JL, May PE. Dinucleotide repeat polymorphism at the D22S156 locus. Nucleic Acids Res. 1990 Aug 11;18(15):4639. PMCID: PMC331334

115. Weber JL, Kwitek AE, May PE. Dinucleotide repeat polymorphism at the D15S87 locus. Nucleic Acids Res. 1990 Aug 11;18(15):4640. PMCID: PMC331335

116. Weber JL, Kappel C, May PE, Kwitek AE. Dinucleotide repeat polymorphism at the D19S75 locus. Nucleic Acids Res. 1990 Aug 11;18(15):4639. PMCID: PMC331333

117. Weber JL, Kwitek AE, May PE. Dinucleotide repeat polymorphism at the D14S34 locus. Nucleic Acids Res. 1990 Aug 11;18(15):4638. PMCID: PMC331332

118. Weber JL, Kwitek AE, May PE. Dinucleotide repeat polymorphism at the D13S71 locus. Nucleic Acids Res. 1990 Aug 11;18(15):4638. PMCID: PMC331331

119. Weber JL, Kwitek AE, May PE, Polymeropoulos M. Dinucleotide repeat polymorphism at the D12S43 locus. Nucleic Acids Res. 1990 Aug 11;18(15):4637. PMCID: PMC331330

120. Weber JL, Kwitek AE, May PE. Dinucleotide repeat polymorphism at the D6S87 locus. Nucleic Acids Res. 1990 Aug 11;18(15):4636. PMCID: PMC331328

121. Weber JL, Kwitek AE, May PE, Killary AM. Dinucleotide repeat polymorphism at the D4S174 locus. Nucleic Acids Res. 1990 Aug 11;18(15):4636. PMCID: PMC331327

122. Weber JL, Kwitek AE, May PE, Wallace MR, Collins FS, Ledbetter DH. Dinucleotide repeat polymorphisms at the D17S250 and D17S261 loci. Nucleic Acids Res. 1990 Aug 11;18(15):4640. PMCID: PMC331336

123. Weber JL, Kwitek AE, May PE. Dinucleotide repeat polymorphism at the CRP locus. Nucleic Acids Res. 1990 Aug 11;18(15):4635. PMCID: PMC331325

124. Weber JL, Kwitek AE, May PE. Dinucleotide repeat polymorphisms at the D16S260, D16S261, D16S265, D16S266, and D16S267 loci. Nucleic Acids Res. 1990 Jul 11;18(13):4034. PMCID: PMC331147

125. Weber JL, Kwitek AE, May PE, Polymeropoulos MH, Ledbetter S. Dinucleotide repeat polymorphisms at the DXS453, DXS454 and DXS458 loci. Nucleic Acids Res. 1990 Jul 11;18(13):4037. PMCID: PMC331150

126. Weber JL, Kwitek AE, May PE. Dinucleotide repeat polymorphisms at the D11S419 and CD3D loci. Nucleic Acids Res. 1990 Jul 11;18(13):4036. PMCID: PMC331149

127. Weber JL, Kwitek AE, May PE. Dinucleotide repeat polymorphisms at the D7S435 and D7S440 loci. Nucleic Acids Res. 1990 Jul 11;18(13):4039. PMCID: PMC331152

128. Weber JL, Kwitek AE, May PE, Patterson D, Drabkin H. Dinucleotide repeat polymorphisms at the D8S85, D8S87, and D8S88 loci. Nucleic Acids Res. 1990 Jul 11;18(13):4038. PMCID: PMC331151

129. Weber JL, Kwitek AE, May PE. Dinucleotide repeat polymorphisms at the D5S107, D5S108, D5S111, D5S117 and D5S118 loci. Nucleic Acids Res. 1990 Jul 11;18(13):4035. PMCID: PMC331148

130. Weber JL, Kwitek AE, May PE. Dinucleotide repeat polymorphism at the D1S104 locus. Nucleic Acids Res. 1990 May 11;18(9):2835. PMCID: PMC330796

131. Weber JL, Kwitek AE, May PE. Dinucleotide repeat polymorphism at the D1S102 locus. Nucleic Acids Res. 1990 Apr 25;18(8):2199. PMCID: PMC330725

132. Weber JL, Kwitek AE, May PE. Dinucleotide repeat polymorphism at the D1S103 locus. Nucleic Acids Res. 1990 Apr 25;18(8):2199. PMCID: PMC330726

1. Laulederkind SJF, Hayman GT, Wang SJ, Kaldunski ML, Vedi M, Demos WM, Tutaj M, Smith JR, Lamers L, Gibson AC, Thorat K, Thota J, Tutaj MA, de Pons JL, Dwinell MR, Kwitek AE. The Rat Genome Database: Genetic, Genomic, and Phenotypic Data Across Multiple Species. Curr Protoc. 2023 Jun;3(6):e804. PMCID: PMC10335880

2. Clark KC, Kwitek AE. Multi-Omic Approaches to Identify Genetic Factors in Metabolic Syndrome. Compr Physiol. 2021 Dec 29;12(1):3045-3084. PMCID: PMC9373910

3. Kwitek AE. Rat Models of Metabolic Syndrome. Methods Mol Biol. 2019;2018:269-285. PMCID: PMC7315404

4. Moreno C, Lazar J, Jacob HJ, Kwitek AE. Comparative genomics for detecting human disease genes. Adv Genet. 2008;60:655-97.

5. Cuppen E, Hübner N, Jacob HJ, Kwitek AE (senior author). Model Systems - The Rat . (2007) in Genetic Variation: A Laboratory Manual, CSHL Press, Cold Spring Harbor, NY. ISBN 978-087969780-8.

6. Kwitek AE, Olivier M. Genetic Markers and Genotyping Analyses for Genetic Disease Studies Handbook of Pharmaceutical Biotechnology. 24 August 2006:661-689.

7. Hessner MJ, Liang M, Kwitek AE. The application of microarray analysis to pediatric diseases. Pediatr Clin North Am. 2006 Aug;53(4):579-90.

8. Lazar, J, Moreno, C, Jacob, HJ, Kwitek, AE. Impact of Genomics on Research in the Rat . (2006) in Genomes, (ed. HE Sussman and MA Smit), pp. 281-311, CSHL Press, Cold Spring Harbor, NY..

9. Lazar J, Moreno C, Jacob HJ, Kwitek AE. Impact of genomics on research in the rat. Genome Res. 2005 Dec;15(12):1717-28.

10. Kwitek, AE. Physiological Genomics . (2003) in Physiology Secrets, 2nd edition (ed. H Raff), pp. 57-62, Hanley and Belfus, Inc, Philadelphia, PA..

11. Jacob HJ, Kwitek AE. Rat genetics: attaching physiology and pharmacology to the genome. Nat Rev Genet. 2002 Jan;3(1):33-42.

12. Kwitek-Black AE, Jacob HJ. The use of designer rats in the genetic dissection of hypertension. Curr Hypertens Rep. 2001 Feb;3(1):12-8.

13. Kwitek-Black AE. The Role of Rats in Functional Genomics Lab Animal. March 2000;29(3):44-48.

1. Alliance of Genome Resources Consortium . Updates to the Alliance of Genome Resources Central Infrastructure Alliance of Genome Resources Consortium. bioRxiv. 2023 Nov 22. PMCID: PMC10690154

2. de Jong TV, Pan Y, Rastas P, Munro D, Tutaj M, Akil H, Benner C, Chen D, Chitre AS, Chow W, Colonna V, Dalgard CL, Demos WM, Doris PA, Garrison E, Geurts AM, Gunturkun HM, Guryev V, Hourlier T, Howe K, Huang J, Kalbfleisch T, Kim P, Li L, Mahaffey S, Martin FJ, Mohammadi P, Ozel AB, Polesskaya O, Pravenec M, Prins P, Sebat J, Smith JR, Solberg Woods LC, Tabakoff B, Tracey A, Uliano-Silva M, Villani F, Wang H, Sharp BM, Telese F, Jiang Z, Saba L, Wang X, Murphy TD, Palmer AA, Kwitek AE, Dwinell MR, Williams RW, Li JZ, Chen H. A revamped rat reference genome improves the discovery of genetic diversity in laboratory rats. bioRxiv. 2023 Sep 28. PMCID: PMC10197727

3. McCarthy, F.M.; Jones, T.E.; Kwitek, A.E.; Smith, C.L.; Vize, P.D.; Westerfield, M.; Bruford, E.A.. The Case for Standardising Gene Nomenclature Across Vertebrates Preprints. Preprints 2021, 2021090485 (doi: 10.20944/preprints202109.0485.v1).