CURRICULUM VITAE
Hershel Raff PhD
Hershel Raff PhD
Professor
Department of Academic Affairs
Division of Medical Education
Department of Academic Affairs
Division of Medical Education
OFFICE ADDRESS: |
Health Research Center |
8701 Watertown Plank Rd |
Milwaukee, WI 53226 |
EDUCATION: |
1975 BA, Union College, Schenectady, NY |
1981 PhD, Johns Hopkins University, Baltimore, MD |
POSTGRADUATE TRAINING AND FELLOWSHIP APPOINTMENTS: |
1980 - 1983 NRSA Post Doctoral Fellow, Department of Physiology, University of California- San Francisco, San Francisco, CA |
FACULTY APPOINTMENTS: |
1983 - 1987 Assistant Professor of Medicine, Assistant Professor of Physiology, Medical College of Wisconsin, Milwaukee, WI |
1987 - 1991 Associate Professor of Medicine, Associate Professor of Physiology, Medical College of Wisconsin. |
1988 - 1991 Adjunct (Visiting) Associate Professor of Physiology, University of Florida College of Medicine, Gainesville, FL |
1989 - Present Graduate Faculty of the College, Medical College of Wisconsin |
1991 - 1998 Adjunct (Honorary Visiting) Professor of Physiology, University of Florida College of Medicine. |
1991 - Present Professor of Medicine (with Tenure), Professor of Physiology, Medical College of Wisconsin |
1999 - 2001 Clinical Professor, Department of Health Sciences, School of Allied Health Professionals, University of Wisconsin-Milwaukee, WI. |
2000 - Present Adjunct Professor, Department of Biomedical Sciences, Marquette University College of Health Science, Milwaukee, WI |
2011 - Present Professor of Surgery, Medical College of Wisconsin |
2017 - Present Professor, School of Pharmacy, Medical College of Wisconsin, Milwaukee, WI |
HOSPITAL AND CLINICAL ADMINISTRATIVE APPOINTMENTS: |
1983 - 2022 Scientific Director and Clinical Supervisor, CAP #17782-04 CLIA ID# 52D0881919 Maryland Permit #1647, Endocrine Research Laboratory, Aurora St. Luke's Medical Center, Milwaukee, WI |
AWARDS AND HONORS: |
1975 cum laude with Distinction in the Arts, Union College |
1981 Delta Omega Honorary Public Health Society |
1990 Society of Teaching Scholars, Medical College of Wisconsin (Inaugural Inductee) |
1993 The Harry Beckman Basic Science Teaching Award presented by the Senior Class of the Medical College of Wisconsin |
2001 The Harry Beckman Basic Science Teaching Award presented by the Senior Class of the Medical College of Wisconsin |
2001 Graduate School of Biomedical Sciences Student Award for Outstanding Teacher, Medical College of Wisconsin |
2004 Louis D'Agrosa Memorial Lecture, St. Louis University School of Medicine (October) |
2005 Fellow of the American Association for the Advancement of Science, February |
2005 Elected to Alpha Omega Alpha (AOA), Medical College of Wisconsin (April) |
2006 Outstanding Reviewer Recognition Award, Journal of Clinical Endocrinology and Metabolism |
2008 MCW's Outstanding Medical Student Teacher for 2007-2008 |
2009 MCW's Outstanding Medical Student Teacher for 2008-2009 |
2010 Collaborative Research Award, Aurora Health Care |
2010 MCW's Outstanding Medical Student Teacher for 2009-2010 |
2011 The Harry Beckman Basic Science Teaching Award presented by the Senior Class of the Medical College of Wisconsin |
2011 MCW Outstanding Medical Student Teacher for 2010-2011, MCW |
2012 Outstanding Faculty Service Award from the MCW Faculty Council, MCW |
2013 MCW Outstanding Medical Student Teacher for 2012-2013 |
2015 MCW Outstanding Medical Student Teacher for 2014-2015 |
2015 APSselect Article - Am J Physiol Regul Integr Comp Physiol 308: R73–R77, 2015 |
2015 Endocrinology 2014 Best Reviewer |
2015 Fellow of the American Physiological Society (Inaugural Class). |
2015 T. Michael Bolger Standing Ovation Award presented by the Student Assembly of the Medical College of Wisconsin |
2016 The Harry Beckman Basic Science Teaching Award presented by the Senior Class of the Medical College of Wisconsin |
2016 MCW Outstanding Medical Student Teacher for 2015-2016 |
2017 MCW Outstanding Medical Student Teacher for 2016-2017 |
2017 APSselect Article - Am J Physiol Regul Integr Comp Physiol 314:R12-R21, 2018 |
2017 Distinguished Service Award from the Association of Chairs of Departments of Physiology (ACDP) |
2018 MCW Outstanding Faculty Service Award from the MCW Faculty Council |
2020 First Place Oral Presentation, Aurora Research Institute Scientific Day. |
2020 MCW Outstanding Medical Student Teacher for 2019-2020 |
2020 The Harry Beckman Basic Science Teaching Award presented by the Senior Class of the Medical College of Wisconsin |
2020 MCW Outstanding Faculty Service Award from the MCW Faculty Council |
2021 MCW Outstanding Medical Student Teacher for 2020-2021 |
2021 Gabrilove Lecturer – Mt Sinai Icahn Medical School, New York |
2021 First Place Oral Presentation, Advocate Aurora Research Institute Scientific Day |
2021 Distinguished Lecturer - Indonesian Physiological Society. |
2022 First Place Oral Presentation, Advocate Aurora Research Institute Scientific Day |
2022 MCW Outstanding Medical Student Teacher for 2021-2022 |
MEMBERSHIPS IN HONORARY AND PROFESSIONAL SOCIETIES: |
2001 - 2007 American Physiological Society: Finance Committee, Nominating Committee (Council (Ex officio)) |
2003 - 2007 The Endocrine Society (Council (Ex-officio 2003-2004; Voting 2004-2007)) |
2012 The Endocrine Society (ENDO2013 Abstract Reviewer ) |
2012 - 2017 American Physiological Society (Physiology Joint Management Board ) |
2012 - 2015 The Endocrine Society (Committee on Governance Affairs ) |
2012 - 2014 American Physiological Society (Physiological Reports Joint Management Board ) |
2012 - 2015 American Physiology Society (APS Representative to the FASEB Journal Editorial Board ) |
2013 - 2015 American Physiological Society (Water and Electrolyte Homeostasis Steering Committee ) |
2014 The Endocrine Society (ENDO2015 Abstract Reviewer ) |
2015 - 2016 American Physiology Society (Vice-Chair for Publication Ethics, Publications Committee ) |
2015 The Endocrine Society (ENDO2015 Presidential Poster Competition Judge ) |
2015 American Physiological Society (Fellow of the American Physiological Society ) |
2015 - 2018 American Physiological Society (FASEB Publications and Communications Committee ) |
2016 The Endocrine Society (ENDO2016 Presidential Poster Competition Judge ) |
2018 - 2021 American Physiological Society (Membership and FAPS Committee ) |
2018 The Endocrine Society (ENDO2018 Abstract Reviewer ) |
2019 The endocrine Society (ENDO2019 Abstract Reviewer ) |
2020 The Endocrine Society (ENDO2020 Abstract Reviewer ) |
2021 The Pituitary Society (Position Statement Committee – Effects of Opioids on Pituitary Function ) |
2022 The Endocrine Society (ENDO2022 Late Breaking Abstract Reviewer ) |
2023 The Endocrine Society (ENDO2023 Abstract Reviewer ) |
Endocrine Society: Secretary-Treasurer (2004-2007) |
Endocrine Society Secretary-Treasurer: Chair (Androgen Assay Working Group (2005-2006)) |
Endocrine Society: Publications Core Committee (2007-2010) |
Endocrine Society Publications Core Committee: Educational Publications Task Force (2007-2010) (Chair (2008)) |
Endocrine Society: Trainee and Career Development Core Committee (2010-2011) |
Endocrine Society: ENDO2011 Abstract Reviewer (2011) |
Sigma Xi |
Council for High Blood Pressure Research (American Heart Association) |
American Association for the Advancement of Science, AAAS APS Representative to the Section on Biological Sciences (1999-2001) |
American Association for the Advancement of Science, AAAS Fellow in Biological Sciences (2005) |
American Association for Laboratory Animal Science (National Silver Member) |
Alpha Omega Alpha - Honor Medical Society (Elected 2005) |
American Association for Laboratory Animal Science (National Silver Member) |
Endocrine Society: Hormone Foundation Committee (Ex-Officio 2004-2007) |
Endocrine Society: Corporate Liaison Board (Ex-Officio 2003-2006) |
Endocrine Society Publications Oversight Committee: Publications Strategic Analysis Task Force (2005-2006) |
Endocrine Society Publications Oversight Committee: Journals Operations Subcommittee (Ex-Officio 2004-2007) |
Endocrine Society Publications Oversight Committee: Journals Management Subcommittee (Ex-Officio 2004-2007) |
Endocrine Society Publications Oversight Committee: New Initiatives Subcommittee (Ex-Officio 2004-2007) |
Endocrine Society Publications Oversight Committee (Ex-Officio 2004-2007) |
Endocrine Society: Performance and Compensation Steering Committee (2003-2007 (Chair 2004-2007)) |
Endocrine Society: Executive Committee (2003-2007) |
Endocrine Society: Council (Ex-officio 2003-2004; Voting 2004-2007) |
Endocrine Society: Secretary-Treasurer Elect (2003-2004) |
Endocrine Society: ENDO2003 Task Force on Cardiovascular Endocrinology Theme |
Endocrine Society: Finance Committee (Ex-Officio 2001-2007) |
Endocrine Society: Development Committee (2000-2003); Chair - (2001-2003) (Ex officio (2003-2005)) |
Endocrine Society: Associate Editor (Endocrine News (1994-1998)) |
Endocrine Society: Advisory Panel (Endocrine News (1993)) |
American Physiological Society: Chair (Publications Committee (2011-2014)
Book Committee, Finance Committee, Nominating Committee, Council (Ex officio)) |
American Physiological Society: Chair (Task Force on Classic Papers (2002-2006)) |
American Physiological Society: Publications Committee (2000-2003) |
American Physiological Society: Long-Range Planning Committee (1996-1998) |
American Physiological Society: Program Advisory Committee (1989-1992) |
American Physiological Society: Steering Committee 1991 Fall Meeting |
EDITORSHIPS/EDITORIAL BOARDS/JOURNAL REVIEWS: |
Editorship |
1993 - 1995 American Journal of Physiology: Regulatory, Integrative, and Comparative Physiology |
1994 - 1998 Associate Editor, Endocrine News (a publication of the Endocrine Society) |
2004 - Present Faculty of 1000, Physiology, Head of the Endocrinology Section |
2005 - 2011 Advances in Physiology Education |
2012 - 2019 Topic Editor, Comprehensive Physiology – Adrenal Gland and Stress |
2018 - Present Editor, Clinical Laboratory Testing: UpToDate – Hypothalamic-Pituitary Adrenal Function |
2020 - Present Associate Editor, Endocrinology |
Editorial Board |
1986 - 1992 American Journal of Physiology: Regulatory, Integrative, and Comparative Physiology |
1988 - 1994 American Journal of Physiology: Endocrinology and Metabolism |
1993 - 1996 American Journal of Physiology: Regulatory, Integrative, and Comparative Physiology |
2005 - 2008 Endocrinology |
2007 - 2011 American Journal of Physiology: Regulatory, Integrative and Comparative Physiology |
2008 - Present UpToDate Peer Reviewer for Endocrinology |
2011 - 2014 Endocrine |
2012 - 2015 FASEB Journal |
2014 - Present International Editorial Board, IBIMA Publishing - International Journal of Case Reports in Medicine |
2015 - 2018 Endocrinolgy |
2018 - 2020 Physiological Reviews |
2018 - 2021 FASEB BioAdvances |
2018 - Present American Journal of Physiology: Regulatory, Integrative and Comparative Physiology |
2021 - 2022 Journal of the Endocrine Society |
Journal Review |
Frontiers in Endocrinology |
Stress |
Journal of the Endocrine Society |
Journal of Clinical Medicine |
Clinical Obesity |
Translational Research |
Intensive Care Medicine |
Endocrine Research |
Pituitary |
PLOS ONE |
Endocrine Connections |
Clinical Endocrinology |
FASEB Journal |
BMJ Case Reports |
Journal of Vascular Diagnostics |
Hormones and Cancer |
Comprehensive Physiology |
Journal of Endocrinology |
Pediatrics |
Neuroendocrinology |
Nature Endocrine Reviews |
International Journal of Chronic Disease |
Journal of Thermal Biology |
Endocrine Practice |
JCI Insight |
Journal of Pharmacology and Experimental Therapeutics |
Advances in Physiology Education |
European Journal of Neuroscience |
Lancet |
Journal of Clinical Investigation |
New England Journal of Medicine |
Annals of Internal Medicine |
American Heart Journal |
Regulatory Peptides |
Chest |
Hypertension |
Acta Endocrinologica |
American Journal of Physiology |
Circulation Research |
Journal of Applied Physiology |
Neuroendocrinology |
Endocrinology |
Peptides |
Southern Medical Journal |
American Review of Respiratory Disease |
Domestic Animal Endocrinology |
Prostaglandins |
American Journal of Medical Sciences |
Life Sciences |
Journal of Physiology (London) |
Alcoholism: Clinical and Experimental Research |
Clinical Chemistry |
Clinical Endocrinology |
Journal of Clinical Endocrinology and Metabolism |
Biology of Reproduction |
Central European Journal of Medicine |
Medicine and Science in Sports and Exercise |
Neuropeptides, Research in Veterinary Science |
Proceedings of the Society for Experimental Biology and Medicine Experimental Neurology |
Molecular and Cellular Neurosciences |
Metabolism, Neuroscience |
Neuroscience Letters |
Canadian Journal of Physiology and Pharmacology |
Molecular and Cellular Endocrinology |
Calcified Tissue International |
European Journal of Endocrinology |
Developmental Brain Research |
Journal of Endocrinological Investigation |
Methods and Findings in Experimental and Clinical Pharmacology |
Clinical Chemistry and Laboratory Medicine |
Physiological Genomics |
Archives Italiennes de Biologie |
International Journal of Endocrinology |
Expert Review of Endocrinology and Metabolism |
Postgraduate Medical Journal |
Proceedings of the National Academy of Sciences (PNAS) |
Steroids |
Rapid Communications in Mass Spectrometry |
British Journal of Anesthesia |
Hormone and Metabolic Research |
Journal of Clinical Pathology |
Current Neuropharmacology |
Journal of Pediatric Endocrinology and Metabolism |
Molecular Neurobiology |
BMC Endocrine Disorders |
International Journal of Endocrinology |
Expert Review of Endocrinology and Metabolism, |
Endocrine |
Journal of Patient-Centered Research and Reviews |
AACE Journals: Clinical Case Reports |
Scientific Reports |
Hypertension |
LOCAL/REGIONAL APPOINTED LEADERSHIP AND COMMITTEE POSITIONS: |
1989 - 1993 American Heart Association Wisconsin Affiliate Research Peer Review Committee |
1990 - 2000 Vince Lombardi Cancer Center Education/Control Committee |
Founder, Milwaukee Neuroendocrine Group (merged with Milwaukee Neuroscience Group) |
Badger State Science and Engineering Fair Judge, 2007 |
Milwaukee Neuroscience Group |
Milwaukee Alumni Representative, Union College |
Badger State Science and Engineering Fair Judge, 2008 |
NATIONAL ELECTED/APPOINTED LEADERSHIP AND COMMITTEE POSITIONS: |
02/1992 Louisiana Education Quality Support Fund Research Competitiveness Subprogram Out of state Expert |
02/1992 National Institutes of Health, Endocrinology Study Section Special Reviewer |
03/1992 American Institute of Biological Sciences (AIBS) Space Physiology and Countermeasures Peer Review to NASA |
1993 - 1997 Member, International and Cooperative Projects (ICP) Study Section, National Institutes of Health |
1995 National Science Foundation, Reviewer, Integrative Animal Biology Grant |
02/1998 National Institutes of Health, International and Cooperative Projects (ICP) Study Section - Special Reviewer |
07/1998 National Institutes of Health, International and Cooperative Projects (ICP) Study Section - Special Reviewer |
10/1998 National Institutes of Health, International and Cooperative Projects (ICP) Study Section - Special Reviewer |
10/1999 National Institutes of Health, International and Cooperative Projects (ICP) Study Section - Special Reviewer |
1999 - 2001 American Heart Association Great America 3B Affiliate Study Group |
06/2002 National Institutes of Health, National Institute of Child Health and Human Development, Extramural Reviewer |
08/2002 National Institutes of Health, Global Health Research Initiative Program (GRIP) Special Emphasis Panel |
10/2002 National Institutes of Health, Human Embryology and Development 1 (HED1) Study Section, Special Reviewer |
02/2003 National Institutes of Health, International and Cooperative Projects (ICP) Study Section - Special Reviewer |
04/2003 National Institutes of Health, Experimental Therapeutics Study Section (ET-2) Special Emphasis Panel on Hypoxia |
07/2003 Special Emphasis Panel ZRG1 ICP-2, Global Health Research Initiative Program (GRIP), National Institutes of Health |
12/2003 - Present Health Research Council of New Zealand, Referee |
02/2004 National Institutes of Health, International and Cooperative Projects (ICP) Study Section - Special Reviewer |
08/2004 National Institutes of Health, National Institute of Child Health and Human Development, Extramural Reviewer |
11/2004 National Institutes of Health, Endocrinology, Metabolism, Nutrition, and Reproductive Sciences Integrated Review Group, Special Emphasis Panel, ZRG1 EMNR-F 02 |
12/2004 National Institutes of Health, Global Health Research Initiative Program (GRIP) Special Emphasis Panel ZRG1 ICP-2 |
2004 - Present Head of the Endocrinology Section, Faculty of 1000, Physiology |
07/2005 National Institutes of Health, International and Cooperative Projects (ICP) Study Section - Mail Reviewer |
11/2005 National Institutes of Health, Endocrinology, Metabolism, Nutrition and Reproductive Sciences Integrated Review Group, Ad Hoc Study Section, ZRG1 EMNR F(02) |
07/2008 Cancer Research UK - Translational Research in Clinical Trials Committee, Ad Hoc Reviewer |
07/2008 National Institutes of Health, Global Health Research Initiative Program (GRIP) Special Emphasis Panel ZRG1 ICP-2 |
09/2008 American Institute of Biological Sciences, Investigator-Initiated Research Awards PRMRP, Reviewer - Integrated Tissue Hypoxia Research Panel |
07/2011 Ad hoc reviewer of report, National Research Council Committee on Guidelines for Scientific Publications Involving Animal Studies, Institute for Laboratory Animal Research, ILAR |
2013 Elected Member, Partnership for the Accurate Testing of Hormones (PATH) |
04/2016 Ad hoc reviewer, University of Michigan Geriatrics Center Pilot Grants Program, Claude Pepper Older Americans Independence Center |
04/2016 Ad hoc reviewer, Research Grants Council (RGC) of Hong Kong |
09/2016 Grant Reviewer, National Science Center, Poland |
11/2016 Barts Charity Clinical Research Training Fellowship |
12/2016 Clinical and Translational Institute (CTSI) of Southeastern Wisconsin Pilot Scientific Review Committee |
02/2018 Grant Reviewer, Medical Research Council of the United Kingdom |
06/2018 Oncology & Cardio-Oncology Scientific Review Committee, Aurora Research Institute |
01/2019 Cardiac Research Award Scientific Review Committee, Aurora Research Institute |
05/2020 Seed Grant Review Committee, Advocate Aurora Research Institute |
07/2020 Grant Reviewer, Developmental Pathway Funding Scheme, Medical Research Council (United Kingdom) |
2020 Neuroscience Intramural Research Award Executive Council., Advocate Aurora Research Institute |
2021 - 2022 Merit Reviewer, Advancing a Healthier Wisconsin Endowment (AHW) |
02/2022 Advocate Aurora Research Institute, Intramural Scientific Review Committee, Advocate Aurora Health |
06/2022 We Care Fund Scientific Review Committee, Department of Surgery, Medical College of Wisconsin |
Veterans Administration Merit Review ad hoc reviewer |
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INVITED LECTURES/WORKSHOPS/PRESENTATIONS: |
International |
Sixth International Hypoxia Symposium. Poster Symposium: "Adrenal glomerulosa cells are oxygen sensitive: low PO2 inhibits aldosteronogenesis in vitro." Lake Louise, Canada, 1989 |
Seventh International Hypoxia Symposium Organizer: Hormonal Control of Fluid and Electrolyte Balance in Hypoxic States, and Speaker: "The renin angiotensin aldosterone system: is the adrenal an oxygen sensor? Lake Louise, Canada, 02/1991 |
“Basic and Clinical Physiology: A Team Approach”, Association of Chairs of Departments of Physiology (ACDP): Distinguished Service Award Lecture, Jamaica, 12/2017 |
“Endocrinology: Physiology and Pathophysiology”,, Indonesian Physiological Society – Distinguished Lecturer. Guest Lecture Series for Medical Students. Federation of Asian and Oceanic Physiological Societies (FAOPS) and International Union of Physiology Sciences (IUPS)., 11/2021 |
National |
Johns Hopkins Medical Institutions, School of Hygiene and Public Health, Department of Environmental Health Sciences, Baltimore, MD, 1982 |
Loma Linda University, Department of Physiology, Division of Perinatal Biology, Loma Linda, CA, 1983 |
University of San Francisco, Department of Biology, San Francisco, CA, 1983 |
UMDNJ Robert Wood Johnson Medical School (Rutgers), Department of Medicine, Pulmonary Division, New Brunswick, NJ, 1984 |
Johns Hopkins Hospital, Department of Anesthesiology, Baltimore, MD, 1984 |
University of Tennessee, School of Medicine, Department of Physiology and Biophysics, Memphis, TN, 1985 |
University of California, Davis. Department of Animal Physiology. Davis, CA, 1986 |
State University of New York, Buffalo. School of Medicine and Dentistry, Department of Physiology, Buffalo, NY, 1987 |
Second International Vasopressin Conference. "Interaction of the Vasopressin and CRF ACTH adrenocortical Control Systems". Vermont, 1987 |
FASEB Symposium Organizer American Physiological Society Centential Symposium: Cardiopulmonary Neuroendocrine Interactions and Speaker "Neuroendocrine Responses to Hypoxia and Hypercapnia", Washington, D.C., 1987 |
University of Florida, College of Medicine. Department of Medicine Division of Nephrology. Gainesville, FL., 1988 |
American Thoracic Society Annual Meeting. Clinical Topics In Pulmonary Medicine: Fluid Balance in Acute and Chronic Lung Disease. "The pituitary adrenal response to hypoxemia and hypercapnic acidosis", Las Vegas, NV., 1988 |
Co chairman, Vasopressin Session. FASEB Annual Meeting (American Physiological Society Section), Las Vegas, NV., 1988 |
University of Florida, College of Medicine. Department of Physiology. Gainesville, FL., 1988 |
Third Conference on the Adrenal Cortex. "The effect of hypoxia (low PO2) on aldosterone secretion in vitro." New Orleans, LA, 1989 |
University of Florida, College of Medicine. Department of Physiology. Gainesville, FL., 1989 |
University of Florida, College of Medicine. Department of Medicine Division of Nephrology. Gainesville, FL., 1989 |
University of Florida, College of Pharmacy. Department of Pharmacodynamics. Gainesville, FL, 1990 |
University of Florida, College of Medicine. Department of Physiology. Gainesville, FL., 1990 |
Boston University Department of Biology, Boston, MA, 1990 |
FASEB/APS Meeting Session Chairman (Aldosterone). Washington, D.C., 1990 |
University of Tennessee College of Medicine, Department of Physiology Biophysics, Memphis, TN, 01/1991 |
FASEB '91 Symposium Organizer: Endocrine Adaptation to Hypoxia; and Speaker: "Effect of hypoxia on the renin angiotensin aldosterone system". Atlanta, Georgia, 04/1991 |
FASEB '91 Meeting Session Chairman (Hypoxia, Altitude, Gravitational Biology I), Atlanta, Georgia, 04/1991 |
Johns Hopkins Medical Institutions, Department of Anesthesia and Critical Care Medicine, Baltimore, MD, 06/1991 |
APS Specialty Meeting: Interactions of the Endocrine and Cardiovascular Systems in Health and Disease; Steering Committee and Symposia Organizer: Mechanisms of Endocrine Hypertension; and Methods of Hormone Measurement, San Antonio, TX, 09/1991 - 10/1991 |
FASEB/APS Workshop on Careers in Physiology. Speaker, "Career opportunities in a Department of Medicine, and as a director of a Clinical Laboratory". Anaheim, CA, 04/1992 |
New York Academy of Science Conference: The Neurohypophysis: A Window on Brain Function. Speaker: "Interactions between Neurohypophyseal Hormones and the ACTH adrenocortical Axis. Dartmouth College, 07/1992 |
Chairman, Vasopressin Session, Experimental Biology 1994, Anaheim, CA., 1994 |
Midwest Neurobiologists 18th Annual Meeting, Presenter, UWM, 04/1995 |
Chairman, Vasopressin Session, Experimental Biology 1995, Atlanta, GA., 1995 |
Division of Endocrinology, Diabetes, and Clinical Nutrition. Oregon Health Sciences University, Portland, OR. "Use of immunometric assays in the diagnosis and treatment of Cushing's syndrome and hyperparathyroidism", 09/1996 |
Department of Physiology and Pharmacology, Oregon Health Sciences University, Portland, "Regulation of adrenal steroidogenic enzyme function and expression during hypoxia". September., 09/1996 |
Dupont Merck Pharmaceutical Company, Stine-Haskell Research Center, Newark DE. "Interactions between vasopressin and the CRH-ACTH-adrenocortical control system, 03/1997 |
Kansas City Allergy and Asthma Association, Kansas City, MO. "Systemic effects and HPA axis suppression with inhaled corticosteroids", 04/1997 |
Pediatric Grand Rounds and Endocrine Grand Rounds, Massachusetts General Hospital, Boston, MA. "Systemic effects of inhaled corticosteroids", 06/1999 |
Pediatric Endocrine Conference, Massachusetts General Hospital, Boston, MA. "Neonatal hypoxia: endocrine metabolic interactions", 06/1999 |
Next Steps in Pediatric Asthma. A CME Satellite Symposium of the American Academy of Pediatrics, "Evaluating Systemic Effects and HPA Axis Suppression with Inhaled Corticosteroids, A Pediatric Focus.", 10/2000 |
Clinical Endocrine Conference, Albany Medical College, Albany, NY. "A Physiological Approach to the Diagnosis of Cushing's Syndrome.", 04/2003 |
Endocrine Grand Rounds, Beth Israel Medical Center, New York, NY. "The Diagnosis of Cushing's Syndrome: Is Salivary Cortisol the Answer?", 09/2003 |
Louis D'Agrosa Memorial Lecture. St. Louis University School of Medicine. "The Endocrinology of Stress in the Neonate", 10/2004 |
Alachua County Endocrine Society Meeting, Gainesville, FL. "The Diagnosis and Differential Diagnosis of Cushing's Syndrome", 11/2004 |
Department of Physiology and Functional Genomics Seminar Series, University of Florida, "Hypothalamic-Pituitary-Adrenal Adaptation to Neonatal Hypoxia", 11/2004 |
Invited Speaker: "Endocrine and metabolic adaptations to neonatal hypoxia". Symposium on Oxygen sensing and hypoxia: development, adaptation and disease. XXXV International Congress of Physiological Sciences. San Diego, 04/2005 |
Obstetrics and Gynecology Grand Rounds, Loma Linda University School of Medicine, "The Diagnosis and Differential Diagnosis of Cushing's Syndrome", 05/2005 |
Biomedical Sciences Seminar, Loma Linda University School of Medicine, "Hypothalamic-Pituitary-Adrenal Adaptation to Neonatal Hypoxia", 05/2005 |
Perinatal Biology Research Seminar, Loma Linda University School of Medicine, "Metabolic Adaptations During Neonatal Hypoxia", 05/2005 |
Chair, Oral Session - "Clinical Glucocorticoids" ENDO05, 06/2005 |
The Endocrine Society's 89th Annual Meeting. Workshop Speaker: "Standardization of Testosterone Assays for Clinical Practice: What's the Problem?", 06/2007 |
“Performance of Testosterone and Estradiol Assays – A Review”, CDC Workshop on Improving Steroid Hormone Measurements in Patient Care and Research Translation,, CDC Chamblee Campus, 03/2008 |
The Endocrine Society 90th Annual Meeting, Symposium Organizer and Chair. "Stress & the Central Programming of Behavior", 2008 |
Seattle Pituitary Symposium. Advances in Cushing's Syndrome (Session for Physicians) and A Patient's Road Map to the World of Cushing's Syndrome (Session for Patients). "A Physiological Approach to the Diagnosis and Differential Diagnosis of Cushing's Syndrome, 05/2009 |
Endocrine Days, "A Physiological Approach to the Diagnosis of Cushing's Syndrome and Evaluation of Adrenal Incidentalomas", Seattle, WA, 01/2010 |
Experimental Biology 2011. "Publishing 101: Dos and Don'ts of Publishing in APS Journals. Chair and Speaker, "Preparing Your Work for Publication in APS Journals", 04/2011 |
12th International Pituitary Congress. "Salivary Cortisol Assays, Boston, 06/2011 |
“Intermittent, Acute, and Chronic Neonatal Hypoxia: Endocrine and Metabolic Responses”, University of Nebraska Medical Center, Department of Physiology, 12/2011 |
“Cushing’s Syndrome: A Physiological Approach to Diagnosis and Surveillance”, University of Nebraska Medical Center, Division of Endocrinology, 12/2011 |
“Cushing’s Diagnosis – New Options (Meet the Professor)”, 3th International Pituitary Congress, San Francisco, 06/2013 |
“Diagnosing Diabetes: Benefits and Drawbacks of Glucose vs Hemoglobin A1C", Endocrine Society’s 95th Annual Meeting – ENDO2013 – Symposium Chair, San Francisco, 06/2013 |
Publishing Ethics 101: The Good, The Bad, and The Ugly, Louisiana State University Health Sciences Center, Department of Physiology, 11/2013 |
Gregory J. Bagby Post-Doctoral Fellows Distinguished Lecturer. Short and Long-Term Effects of Neonatal Hypoxia, Louisiana State University Health Sciences Center, Department of Physiology, 2013 |
Symposium Organizer and Chair, “Diagnosing Thyroid Disease: Evaluation of TSH Measurements”, 16th International Congress of Endocrinology/Endocrine Society’s 96th Annual Meeting, Chicago, IL, 06/2014 |
“Publishing Ethics 101: The Good, the Bad, and the Ugly”, Georgia Regents University/Medical College of Georgia College of Graduate Studies, 06/2014 |
“A Physiological Approach to the Diagnosis of Cushing’s Syndrome”, Georgia Regents University/Medical College of Georgia, Department of Medicine, 06/2014 |
Symposium Organizer and Moderator, “Diagnosing Thyroid Disease: Evaluation of TSH Measurements”, AACC 2014 Annual Meeting and Clinical Lab Expo, Chicago, IL, 07/2014 |
“Publishing Ethics 101: The Good, the Bad, and the Ugly”, University of Minnesota Department of Integrative Biology and Physiology, 09/2014 |
“The Short and Long-Term Effects of Neonatal Hypoxia”, University of Minnesota Department of Integrative Biology and Physiology, 09/2014 |
Symposium Organizer and Chair, “AACC Joint Session: Urine Free Cortisol: Pros and Cons”, Endocrine Society’s 97th Annual Meeting & Expo, San Diego, San Diego, CA, 03/2015 |
Symposium Organizer & Chair, “Free Hormone Measurements in Blood: What Clinicians Should Know”,, ENDO2016: Endocrine Society’s 98th Annual Meeting & Expo, Boston, MA, 03/2016 |
ymposium, Speaker, “Laboratory Diagnosis of Cushing Disease: Advances and Pitfalls”, ENDO2016: Endocrine Society’s 98th Annual Meeting & Expo, Boston, MA, 03/2016 |
Symposium Organizer & Chair, “Clinical Assay Issues: What Clinicians Should Know”, ENDO2017: Endocrine Society’s 99th Annual Meeting & Expo, Orlando, FL, 04/2017 |
“Clinical Assay Issues: What Clinicians Should Know”, ENDO2018: Endocrine Society’s 100th Annual Meeting & Expo, Orlando, 03/2018 |
“Patterns of Cortisol Secretion: Do We Blame Parents, Genes, or Diet?”, ENDO2019: Endocrine Society’s 101st Annual Meeting & Expo, New Orleans, 03/2019 |
“Clinical Assay Issues: What Clinicians Should Know”,, ENDO2019: Endocrine Society’s 101st Annual Meeting & Expo,, New Orleans, 03/2019 |
“Updates in Adrenal Steroidogenesis, Therapeutics, and Cancer”,, ENDO2019: Endocrine Society’s 101st Annual Meeting & Expo, New Orleans, Oral Session Co-Chair, New Orleans, 03/2019 |
“Salivary Hormone Testing: Validity and Interpretation”, California Chapter of AACE; 19th Annual Meeting & Symposium., San Francisco, 09/2019 |
“Late Night Salivary Cortisol, including role in Diagnosis of Cyclic Cushing’s”, Pituitary Society Cushing’s Disease Workshop, Update on Diagnosis, Complication Management, and Treatments, 10/2020 |
“Clinical Assay Issues: What Clinicians Should Know”,, ENDO2020: Endocrine Society’s 102nd Annual Meeting & Expo, San Francisco, Symposium Organizer & Chair, San Francisco, 03/2021 |
“Updates on ACTH and cortisol measurement in Clinical Practice”, Endocrine Society Webinar - Hormone Measurements: An Update for the Clinical Endocrinologist, 07/2021 |
. “Clinical Update on the Diagnosis of Adrenal Insufficiency and Cushing’s Syndrome”, Hilda & J. Lester Gabrilove Lecture (Diabetes and Endocrinology Grand Rounds), Icahn School of Medicine at Mount Sinai, New York. Division of Endocrinology, Diabetes, and Bone Disease. The Page and William Black Post-Graduate School, New York, 10/2021 |
“Update on the Laboratory Diagnosis of Adrenal Insufficiency and Cushing’s Syndrome”, Cedars-Sinai Endocrinology & Metabolism ~ Diabetes & Obesity Research Institute Research Seminar Series, Department of Medicine, Division of Endocrinology, Diabetes and Metabolism, and Department of Biomedical Sciences / Diabetes and Obesity Research Institute, 11/2021 |
“ACTH Stimulation Testing: Update on Cortisol Cutoffs”,, UCLA-Greater Los Angeles VA Joint Endocrinology Grand Rounds, Los Angeles, California, 05/2022 |
“What should the serum cortisol cutoffs be for ACTH stimulation tests?", AACC Annual Scientific Meeting & Clinical Lab Expo. Symposium: Clinical Assay Issues: What Endocrinologists Will Ask You, 07/2022 |
Regional |
Northwestern University Medical School, Department of Physiology. Chicago, IL, 1986 |
University of Wisconsin Medical School. Gas Club, Madison, WI, 1990 |
Chicago Chapter, Society for Neuroscience, 1991 Fall Scientific Meeting. Speaker, Neuroendocrine/Neuropeptide Workshop, "Role of glucocorticoids in the secretion of vasopressin", University of Illinois at Chicago, 12/1991 |
University of Wisconsin School of Medicine, Endocrine Section, Endocrine Grand Rounds, "Use of petrosal sinus sampling and the new ACTH IRMA in the differential diagnosis of Cushing's syndrome". Madison, WI, 05/1992 |
Chicago Medical School, Department of Physiology, "Interactions between the Neurohypophysis and the Hypothalamic pituitary adrenal axis", 11/1992 |
Middleton Veterans Administration Hospital, Madison, Wisconsin. "Role of Oxygen in Adrenal Steroidogenesis", 07/1993 |
Cincinnati Allergy and Asthma Society, Cincinnati, OH. "Systemic effects and HPA axis suppression with inhaled corticosteroids.", 04/1997 |
Burns Clinic/North Michigan Hospital, Petoskey, MI. "Systemic effects and HPA axis suppression with inhaled corticosteroids.", 05/1997 |
23rd International Aldosterone Conference, Minneapolis, MN. "Aldosterone synthase (P450c11AS) activity and mRNA expression in adrenal cells from neonatal rats exposed to hypoxia from birth.", 06/1997 |
Co-Chair, Clinical: Adrenal Session: Endo '97 (79th Annual Endocrine Society Meeting), Minneapolis, MN., 06/1997 |
Endocrinology and Metabolism Section, Department of Medicine, Indiana University School of Medicine, "Effect of Hypoxia on the Adrenal Cortex", 07/1997 |
Gundersen Clinic, LaCrosse, WI. "Systemic effects and HPA axis suppression with inhaled corticosteroids.", 08/1997 |
1997 Division of Allergy and Clinical Immunology, Mayo Clinic, Rochester, MI. "Systemic effects and HPA axis suppression with inhaled corticosteroids"., 10/1997 |
Division of Endocrinology, Mayo Clinic, Rochester, MI. "Systemic effects and HPA axis suppression with inhaled corticosteroids", 10/1997 |
Physician's Grand Rounds, Marquette General Hospital, Marquette, MI. "Systemic effects and HPA axis suppression with inhaled corticosteroids", 01/1998 |
Pulmonary Conference OH, Cleveland Clinic Foundation, Cleveland OH, "Systemic effects and HPA axis suppression with inhaled corticosteroids", 01/1998 |
Endocrinology and Metabolism Section, Department of Medicine, Indiana University School of Medicine, "Update on the Diagnosis of Cushing's Syndrome", 03/1998 |
Medical Grand Rounds, Methodist Hospital, Indianapolis, IN, "Systemic effects and HPA axis suppression with inhaled corticosteroids"., 03/1998 |
Department of Physiology and Biophysics, University of Illinois at Chicago, "Neonatal hypoxia: metabolic-adrenal adaptations", 10/1999 |
Seminars in Endocrinology, Metabolism, and Molecular Medicine, Feinberg School of Medicine, Northwestern University, "The Diagnosis and Differential Diagnosis of Cushing's Syndrome", 09/2004 |
Endocrine Grand Rounds, University of Wisconsin, Madison, WI. "The Diagnosis and Differential Diagnosis of Cushing's Syndrome", 11/2004 |
Department of Physiology Seminary, University of Kentucky, The Hypothalamic-Pituitary Adrenal Adaptation to Neonatal Hypoxia", 05/2007 |
Dept. of Internal Medicine Seminar, University of Kentucky: "The Diagnosis and Differential Diagnosis of Cushing's Syndrome", 05/2007 |
Medical Scientist Training Program (MSTP) Annual Retreat (MCW), "Research in a Clinical Setting", Sheboygan, WI, 10/2009 |
Visiting Professor, Carthage College. "Use of Salivary Cortisol in Clinical Medicine and Stress Research", Kenosha, 04/2010 |
Ohio State University College of Nursing. "Use of Salivary Cortisol in Clinical Medicine and Stress Research, Columbus, 05/2010 |
Ohio State University Division of Diabetes and Endocrinology. "A Physiology Approach to the Diagnosis of Cushing's Syndrome", Columbus, 05/2010 |
American Society for Clinical Laboratory Science-Wisconsin (ASCLS-WI) State Convention. "Vitamin D", 04/2011 |
“Intermittent, Acute, and Chronic Neonatal Hypoxia: Endocrine and Metabolic Responses”, University of Chicago Institution for Integrative Physiology and Center for Systems Biology, 10/2011 |
“The Use of Salivary Cortisol in Clinical Research and Diagnosis”, University of Chicago Section of Adult and Pediatric Endocrinology, Diabetes and Metabolism, Department of Medicine, 10/2011 |
“A Physiological Approach to the Diagnosis of Cushing’s Syndrome and Evaluation of Adrenal Incidentalomas”, Indiana University School of Medicine (IUPUI) Endocrine Grand Rounds, 01/2013 |
“Publishing Ethics 101: The Good, The Bad, and The Ugly”, Indiana University School of Medicine (IUPUI) IUSM Graduate Division, 01/2013 |
“Short and Long-Term Effects of Neonatal Hypoxia”, Indiana University School of Medicine (IUPUI) Department of Physiology, 01/2013 |
“HPA Axis Dynamics in Humans During Chronic (and Critical) Illness”, Adrenal 2014: The XVIth Conference on the Adrenal Cortex, Chicago, 06/2014 |
“A Physiological Approach to the Diagnosis and Differential Diagnosis of Cushing’s Syndrome”, Northwestern University Feinberg School of Medicine, Division of Endocrinology, Metabolism, and Molecular Medicine, 01/2016 |
Speaker “Use of Salivary Cortisol as a Screening Tool for Cushing’s Syndrome”, Summer Clinical Symposium – Neurology, Centegra Health System, Crystal Lake, IL, 07/2016 |
“Medical School Admissions”, The Word on Medicine (Radio Show – WISN 1130AM), 03/2021 |
“Physiology of the Endocrine Pancreas and Insulin Sensitivity”, 14th Annual Diabetes Symposium of Wisconsin, 05/2021 |
“The HPA axis and stress: implications in alcoholism and depression.”, Rogers Behavioral Health (Wisconsin). Psychiatric Nurse Practitioners., Wisconsin, 10/2021 |
Local |
Wisconsin Association of Respiratory Therapists, Milwaukee, WI, 1986 |
University of Wisconsin Medical School Milwaukee Clinical Campus, Medical Research Seminar. "Role of Oxygen in Adrenal Steroidogenesis", 09/1992 |
Update on Clinical Endocrinology. Speaker, "How Hormones Work: What Primary Care Physicians Should Know", Hyatt Regency, Milwaukee, 10/1992 |
Wisconsin Association for Biomedical Research, Milwaukee, WI. "Discovery of Ovine CRH", 11/1993 |
Wisconsin Psychiatric Association, Milwaukee, WI. "Update on the Differential Diagnosis of Cushing's Disease.", 1993 |
Midwest Neurobiologists 18th Annual Meeting, Presenter, UWM, 04/1995 |
Speaker, Midwest Physiological Society, Milwaukee, WI, 06/1996 |
Pediatric Update Pre-teleconference, The Female Athlete Triad, "Physiology of Calcium and Bone Metabolism - The Calciotropic Hormones, Children's Hospital of Wisconsin, Milwaukee, WI, 06/1996 |
Update on Clinical Endocrinology, Milwaukee, WI. "Effects of inhaled corticosteroids on the pituitary-adrenal axis and the skeleton", 10/1998 |
Integrated Neuroscience Research Center Seminar, "Hypothalamic-Pituitary-Adrenal Adaptation to Neonatal Hypoxia", Marquette University, 02/2005 |
Milwaukee ENT Society. Update on Thyroid Physiology, 02/2008 |
Pediatric Critical Care Research Conference, Children's Hospital of Wisconsin, "Use of Salivary Cortisol in Clinical Medicine and Stress Research", Milwaukee, 02/2010 |
2010 Marquette Stress Symposium, Integrative Neuroscience Research Center, "The Hypothalamic-Pituitary-Adrenal Adaptation to Acute Neonatal Hypoxia", Milwaukee, 03/2010 |
Departments of Clinical Laboratory Science and Exercise Science, Marquette University, "Vitamin D", Milwaukee, 04/2010 |
“Publishing 101: Dos and Don’ts of Publishing in APS Journals. Chair and Speaker, “Preparing Your Work for Publication in APS Journals”, Experimental Biology 2011, 04/2011 |
“Hypothalamic-Pituitary Adrenal Axis Assessment: The Stress Response in Human Subjects”, Marquette University College of Health Sciences, 02/2012 |
Chair and Speaker, “Preparing Your Work for Publication in APS Journals: Choosing a Journal, Authorship, and Peer Review”, Experimental Biology 2012“Publishing 101: How to Get Your Work Published in APS Journals and Avoid Minefields Along the Way”, 04/2012 |
“Vitamin D”, Wisconsin Seminar Day, ACL Labs, 10/2012 |
Chair and Speaker, “Preparing Your Work for Publication in APS Journals: Choosing a Journal, Authorship, and Peer Review”, Experimental Biology 2013. “Publishing 101: How to Get Your Work Published in APS Journals and Avoid Minefields Along the Way”, 04/2013 |
Chair and Speaker, “Choosing a journal authorship and peer review.”, Experimental Biology 2014. “Publishing 101: How to Get Your Work Published and Avoid Ethical Minefields”., 04/2014 |
“Vitamin D”, Wisconsin (ASCLS-WI) State Convention, American Society for Clinical Laboratory Science-Wisconsin, 04/2014 |
“Hypogonadotrophic Hypogonadism in Diabesity”, MCW Seventh Annual Diabetes Symposium of Wisconsin, Milwaukee, WI, 05/2014 |
COMMITTEE SERVICE: |
Medical College of Wisconsin |
1987 - 1992 Animal Care Committee Chairman |
1987 - 1993 Animal Care Committee |
1987 - 1989 Admissions Interviewer |
1989 - 1992 Faculty Senate |
1989 - 1992 Laboratory Safety Committee |
1989 - 1992 Animal Care Committee Budget Subcommittee |
1990 - Present Society of Teaching Scholars (Inaugural Inductee) |
1990 - 1994 The Ad Hoc Committee on Problem Based Learning |
1993 - 1999 Nominating Committee |
1994 - 1996 LCME Self-Study Task Force Subcommittee on Governance/Administration |
1994 - 1996 LCME Self-Study Task Force |
1996 Orientation to Medical Education for New Faculty Members |
1996 M1-M2 Curriculum Retreat, Lake Geneva, Wisconsin |
1997 - 2002 Continuing Medical Education Committee |
1997 - 2001 Digestive Diseases Research Center Research Committee |
1999 - 2001 Graduate School of Biomedical Sciences Faculty Credentials Committee |
2002 LCME Task Force |
2003 - 2005 Search Committee, Chief of the Division of Endocrinology, Dept of Medicine |
2004 M1/M2 Curriculum Retreat, Wauwatosa, Wisconsin |
2005 - 2008 Rank and Tenure Committee |
2006 - 2008 Advancing a Healthier Wisconsin Initiative Grant Review Committee |
2008 - 2009 Vice-President, Faculty Council |
2009 - 2010 Senior Vice President (President-Elect), Faculty Council |
2010 - 2011 LCME Accreditation Self-Study Task Force |
2010 - 2011 President, Faculty Council |
2010 - 2011 LCME Accreditation Institutional Self-Study Subcommittee |
2011 - Present Honors in Research Committee |
2011 Search Committee-President's Chief of Staff, Faculty Council |
2011 - 2012 Module Director, M2 Endocrinology, Pilot Integrated Curriculum, M2 Endocrinology, Pilot Integrated Curriculum |
2012 - Present Faculty Advisor, Student Assembly (Elected) |
2012 - 2015 Community Medical Education Program Steering Committee |
2012 - Present Unit Director, Discovery M2 Endocrinology/Reproduction Curriculum |
2017 - 2020 Graduate Studies Council Awards Committee |
2017 - 2023 Nominating Committee (Elected) |
2018 - 2019 LCME Self-Study Committee on Education |
2018 Curriculum and Evaluation Committee M1-M2 Grading Taskforce |
2019 - 2022 Graduate Studies Council Course Evaluation Committee |
2019 - Present Clinical and Translation Science Institute of Southeast Wisconsin (CTSI), CTSI Scientific Review Oversight Committee |
2020 Association of American Medical Colleges AAMC 2020 Virtual Medical School Fair, Faculty Representative |
2020 - 2022 Curriculum Task Force – Principle 1 Committee |
2020 - 2023 School of Medicine Curriculum and Evaluation Committee |
2021 - 2024 Graduate School of Biomedical Sciences Council - Rank Committee (Elected) |
2022 - Present Phase 3 (Clinical/Foundational Science Electives) Co-Director – MCWFusion Curriculum |
2022 - Present M2 Curriculum Exam Workgroup |
2023 - Present Primary Member, Cardiovascular Center (CVC) |
Hospital |
1984 - 1994 Institutional Review Board (Human Research Review Committee), St. Luke's Medical Center/Aurora Health Care |
1986 - 1988 Allied Health Committee, St. Luke's Medical Center/Aurora Health Care |
1990 - 1999 Vince Lombardi Cancer Education/Control Committee, St. Luke's Medical Center/Aurora Health Care |
1996 - Present Continuing Medical Education (CME) Subcommittee, St. Luke's Medical Center/Aurora Health Care |
1999 - 2000 Research and Development Committee - Aurora Consolidated Laboratories, St. Luke's Medical Center/Aurora Health Care |
2000 - Present Institutional Animal Care and Use Committee (IACUC)St. Luke's Medical Center/Aurora Health Care |
2000 - 2022 Chairman of IACUC, St. Luke's Medical Center/Aurora Health Care |
2001 - 2022 Radiation Safety Committee, St. Luke's Medical Center/Aurora Health Care |
2003 - 2017 Schroeder Fellows Program Committee, St. Luke's Medical Center/Aurora Health Care |
2003 - 2006 Cardiac Research Fund Award Committee, St. Luke's Medical Center/Aurora Health Care |
MCW TEACHING ACTIVITIES: |
Medical Student Education |
1984 - 2012 Medical Physiology – M1 Students Endocrinology Lectures/Clinical Case Conferences |
1989 - 2007 Otolaryngology Basic Science Course, Review of Pituitary, Thyroid, and Parathyroid Physiology (biannually) |
1989 - 1992 National Board Part I Review Course,Endocrinology Review |
1989 - 1991 Division of Pulmonary and Critical Care Medicine, Department of Medicine Lecture Series on Pulmonary Physiology and Pathophysiology, "Pathogenesis of Hypoxia" |
1991 - 2000 Physiology 271, Graduate Course in Endocrinology and Metabolism |
1992 Department of Biostatistics and Clinical Epidemiology and the Center for the Study of Bioethics and Health Policy, Concepts and Clinical Practice in Medicine, Lectures in Endocrinology |
1993 Neurobehavioral Science, Department of Neurology "Hypothalamus/Neuroendocrinology" |
1994 Preceptor, Minority Summer Research Training Program |
1995 Neurobehavioral Science, Department of Neurology "Hypothalamus/Neuroendocrinology" |
1996 - 2007 Integrated Neuroscience Course, Hypothalamus/Neuroendocrinology Lectures (annually) |
1997 Mini-Medical School ,"Diabetes" |
1999 Mini-Medical School ,"Diabetes" |
2001 - 2007 Advanced Systems Physiology, Endocrine Physiology and Pathophysiology Blocks. (annually) |
2004 - 2012 Medical Pharmacology – M2 Students, Hypothalamic and Pituitary Hormones (annually) |
2007 - Present Bioethics 10444A – Research Ethics Discussion Series |
2008 - 2018 Physiology 08210 – Endocrine Regulation (Course Director – 2009) |
2011 - 2012 Module Director, M2 Endocrinology |
2011 PIC M1 – Diabetes Module; Reproductive Medicine Module |
2012 - 2015 M2 Endocrinology-Reproduction Unit Director Lecturer, M1 Physiology – Endocrinology (10 lecture hours, annually) M2 Symptoms Unit (Fatigue) |
2013 - 2015 Instructor - Diabetic ketoacidosis Foundations of Clinical Medicine (M1 Curriculum) |
2014 - Present Instructor, The Art of Medicine Through the Humanities – Course #520-M4150 (M4 Clerkship) |
2016 - 2022 Aurora GI and Advanced GI Fellowship Programs, Journal Club Co-Director |
2017 - Present Anatomy and Physiology (PHAR 512), School of Pharmacy – Endocrinology and Reproduction, Instructor |
2018 - 2021 KINETICS3 – Kern Institute – Elective “Writing Multiple Choice Questions”. |
2019 - Present Endocrine Core Conferences for Clinical Endocrinology Fellows. Endocrine and Reproductive Physiology, Pathophysiology, and Clinical Chemistry sessions (10 contact hours, annually). |
2019 General Internal Medicine CME Conference: Clinical Cases, Basic Science, November |
2020 - Present Introduction to Organ Systems Physiology – Course 16265, Graduate School of Biomedical Sciences, Course Director (2020-2022) and Instructor (2020-present) |
2020 - Present Spotlight on Science/RCR Refresher Training – Speaker and Discussion Leader: Authorship Ethics |
2022 - Present Phase 1 Endocrinology-Reproductive Unit, Course Director and Instructor, School of Medicine Fusion Curriculum |
2022 - Present M2 Symptoms Course, Instructor, Endocrinology Step 1 Board Review Session, School of Medicine |
Graduate Student Education |
1993 Physiology 275, Graduate Course in Statistical Problems in Physiology |
Community/Lay Public |
1997 - 2007 Apprenticeship in Medicine (AIM) Program for Minority High School Students. "Understanding Diabetes",”Normal Female Reproduction” |
EXTRAMURAL TEACHING: |
Medical Student Education |
1995 - 1997 Marquette University , Program in Physical Therapy, Pathophysiology, Acute Care in Medicine and Surgery "Physiology of Metabolic Bone Disease and Osteoporosis" |
1995 - 1998 Marquette University , Program in Physical Therapy, Pathophysiology, Acute Care in Medicine and Surgery |
1996 University of Wisconsin - Milwaukee, Biological Sciences 630 (Endocrinology), "Adrenal Cortex" |
08/27/1997 - 08/28/1997 National Medical School Review, Endocrine Physiology, Newport Beach, CA, Supplemental Basic Science Review |
1998 Marquette University, Program in Physical Therapy, Pathophysiology, Acute Care in Medicine and Surgery "Physiology of Diabetes Mellitus" |
2003 University of Wisconsin - Milwaukee, Biological Sciences 630 (Endocrinology), "Adrenal Cortex" |
12/2011 University of Nebraska Medical Center, Department of Physiology, Scientific Writing Course, “Publishing Ethics 101: The Good, The Bad, and The Ugly” |
2011 - Present Marquette University College of Health Science “Calcium-Phosphate; Glucose Regulation; HPA Axis lectures”, CTRH 6001 – Applied and Rehabilitative Systems Physiology |
2012 - 2022 M1 Medical Physiology, Instructor, School of Medicine, General Principles of Physiology; Endocrinology/Reproduction, Acid-Base Balance (12 contact hours, annually) |
2017 - Present Medical Students as Teachers – Course MEDI4151 (M4 Clerkship); Instructor, School of Medicine |
12/2020 General Internal Medicine CME Conference: Cushing’s Syndrome for Primary Care Physicians |
MCW STUDENTS, FACULTY, RESIDENTS AND CLINICAL/RESEARCH FELLOWS MENTORED: |
Medical Students |
Timothy P. Roarty, Research Trainee, MCW |
Maryam Ivanoff, Research Trainee, MCW |
Steven C. Griffen, Research Trainee, MCW |
Saeid Kohandarvish, Research Trainee, MCW |
Mark H. Rossing, Research Trainee, MCW |
Sandra K. Doepker, Research Trainee, MCW |
Pedro Lucero, Research Trainee, MCW |
Anne Nagler, Research Trainee, MCW |
Jody VanHoof, Research Trainee, MCW |
Karl Johnson, Research Trainee, MCW |
Maryam Ivanoff, MCW |
Nasha Nensey (Physician Scientist – Molecular and Cellular Research Pathway Advisor, 2014-2017), MCW |
Adam Goldenberg (Physician Scientist – Molecular and Cellular Research Pathway); Advisor, 2016-2019; T35 Training Grant from the National Heart, Lung, Blood institute (NHLBI), MCW |
Christine Huyhn (Quality Improvement and Patient Safety Pathway); Research Advisor 2017, Dr. Michael J. Dunn Medical Student Summer Research Training Fellowship), MCW |
Mark H. Rossing, MCW |
Jonathan Bodager (Clinical Scientist Pathway Advisor, 2013-2016), MCW |
Santiago Rolon (Physician Scientist Pathway Advisor and Research Mentor; 2017-present), MCW |
Kyle Welhouse (Physician Scientist – Research Advisor 2019; National Heart, Lung and Blood Institute (NHLBI) T35 Training Grant), MCW |
Molly Murray (Pathway Advisor – 2019-present), MCW |
Graduate Students |
PhD Committees |
Daniel Brown, MCW |
Christopher Roberts, MCW |
Suzanne Greenberg, MCW |
Ogugua Anene-Maidoh, MCW |
Craig Hanke, MCW |
Melissa Morse, MCW |
Domagoj Mladinov, MCW |
Russell Wilke, MCW |
Mary Pat Kunert, MCW |
MS Committees |
Kristin Anne Koch, MCW |
Andrew Piering, MCW |
Sribidya Kidambi, MCW |
Eric D. Bruder, MCW |
Postdoctoral Researchers |
Gopika SenthilKumar, MD PhD Candidate, Medical Scientist Training Program, MCW |
Clinical/Research Fellows |
Santo J. Diaz, M.D., MCW |
Pennapa Chan, MD, MCW |
Scott Brock, MD, MCW |
Sandra L. Ettema M.D., Ph.D, MCW |
Victor O. Waters, M.D., MCW |
Robert C. Brickner, M.D., MCW |
Manoj H. Majmudar, M.D., MCW |
Thomas P. Segerson, M.D, MCW |
Vidya Kidambi, MD, MCW |
Ty Carroll, MD, MCW |
Jay Mepani, MD, MCW |
Michael Einstein, MD, MCW |
Giovanna Caprirolo, MD, MCW |
Mohamed Tahsin Jouhari, MD, MCW |
Faculty |
Ryan Adam PhD, MCW |
EXTRAMURAL STUDENTS, FACULTY, RESIDENTS, AND CLINICAL/RESEARCH FELLOWS MENTORED: |
High School Students |
Garrett Werner, Science Fair Student, University School of Milwaukee |
Undergraduate Students |
Edward Stauber (1997 Endocrine Society Student Research Fellow), Summer Trainee, University of Wisconsin |
Judson Werner, Summer Trainee, University of Wisconsin |
Jonathan Klinger, Summer Trainee, Marquette University |
John P. Tucker, Summer Trainee, University of Wisconsin |
Seth Auger, Summer Trainee, University of Dayton |
Jennifer Taylor, Summer Trainee, Northwestern University |
Michael Nord, Summer Trainee, University of Minnesota |
Kimberli Kamer, Summer Trainee, University of Wisconsin |
Michael Patrick Kehoe, Summer Trainee, University of Wisconsin |
A. Joseph Tector, III, Summer Trainee, Indiana University |
Genevieve Schmitt, Summer Trainee, College of the Holy Cross |
Mitchell Guenther, Summer Trainee, Lawrence University |
Christopher Wean, Summer Trainee, Renssalaer Polytechnic Institute |
Matthew Schulgit – University of Wisconsin |
Maya Guenther – Lawrence University |
Cole Leonovicz - University of Miami |
Minhal Gardezi – Wellesley College |
Kristin Prewitt – University of Wisconsin |
Kathan Chintamaneni - Washington University of St. Louis |
Hana Siddiqui – University of Wisconsin |
Emily Waples – Duke University |
Thomas Gessert – University of Wisconsin |
Mack Jablonski - Lawrence University |
Medical Students |
Katerini Tori (Kern Project Co-Advisor – 2020-present) |
Graduate Students |
PhD |
Walter Bialkowski, PhD Candidate in Clinical and Translational Rehabilitation Health, CTSI, Marquette university |
Eric D. Bruder, M.S., University of Wisconsin, Milwaukee |
Postdoctoral Researchers |
Paula. E. Papanek, Ph.D. |
Clinical/Research Fellows |
Neil Reisinger, MD – Chief Medical Resident |
Julia Leo MD – GI Fellow |
Joshua Kannankeril MD – Endocrinology and Molecular Medicine Fellow |
Veena Kumaravel MD – GI Fellow |
Jonathan Fahler MD – GI Fellow |
Nebiyu Biru, MD – Chief Medical Resident |
Satyanisth Agrawal MD – GI Fellow |
Brian Rajca MD – GI Fellow |
Rituparna Medda DO – GI Fellow |
Faculty |
2019 - Present Jenna Sarvaideo, DO, MCW – Division of Endocrinology, Department of Medicine |
2021 - Present David Gazeley, MD, MCW Kern Institute Kinetics3 Teaching Academy |
Joshua Timpe MD, Department of Emergency Medicine Kern Institute Kinetics3 Teaching Academy |
Panayotis Fasseas MD, FACC and Sowmya Palam MD |
Thangam Venkatesen, MD, Committee, MCW Division of Gastroenterology, Department of Medicine |
COMMUNITY SERVICE ACTIVITIES: |
1989 - 1993 American Heart Association Wisconsin Affiliate Research Peer Review Committee |
1990 - 2000 Vince Lombardi Cancer Center Education/Control Committee |
2007 Badger State Science and Engineering Fair Judge |
2008 Badger State Science and Engineering Fair Judge |
Milwaukee Alumni Representative, Union College |
Milwaukee Neuroscience Group |
Founder, Milwaukee Neuroendocrine Group (merged with Milwaukee Neuroscience Group) |
BIBLIOGRAPHY |
Refereed Journal Publications/Original Papers |
1. Raff H, Tzankoff SP, and Fitzgerald RS. ACTH and cortisol responses to hypoxia in dogs. J. Appl. Physiol. (Respirat. Environ. Exercise Physiol.) 51:1257 1260, 1981 |
2. Raff H, Tzankoff SP, and Fitzgerald RS. Chemoreceptor involvement in cortisol responses to hypoxia in ventilated dogs. J. Appl. Physiol. (Respirat. Environ. Exercise Physiol.) 52:1092 1096, 1982 |
3. Raff H, Shinsako J, and Dallman MF. Surgery potentiates adrenocortical responses to hypoxia. Proc. Soc. Exp. Biol. Med. 172:400 406, 1983. |
4. Raff H, Shinsako J, Keil LC, and Dallman MF. Vasopressin, ACTH, and corticosteroids during hypercapnia and graded hypoxia in dogs. Am. J. Physiol. (Endocrinol. Metab.) 244:E453 E458, 1983 |
5. Fitzgerald RS, Garger P, Hauer MC, Raff H, and Fechter L. The effect of hypoxia and hypercapnea on catecholamine content in the cat carotid body. J. Appl. Physiol. (Respirat. Environ. Exercise Physiol.) 54:1408 1413, 1983 |
6. Raff H, Shinsako J, Keil LC, and Dallman MF. Vasopressin, ACTH and blood pressure during hypoxia induced at different rates. Am. J. Physiol. (Endocrinol. Metab.) 245:E489 E493, 1983 |
7. Raff H, Shinsako J, Keil LC, and Dallman MF. Feedback inhibition of ACTH and vasopressin responses to hypoxia by physiological increases in endogenous plasma corticosteroids in dogs. Endocrinology 114:1245 1249, 1984 |
8. Raff H and Fagin KD. Measurement of hormones and blood gases during hypoxia in conscious, cannulated rats. J. Appl. Physiol. (Respirat. Environ. Exercise Physiol.) 56:1426 1430, 1984 |
9. Raff H, Shinsako J, and Dallman MF. Renin and ACTH responses to hypercapnia and hypoxia after chronic carotid denervation. Am. J Physiol. (Regulatory, Integrative Comp. Physiol.) 247:R412 R417, 1984 |
10. Fitzgerald RS, Hauer MC, Bierkamper GG, and Raff H. Responses of the in vitro rat diaphragm to changes in acid base balance. J. Appl. Physiol. (Respirat. Environ. Exercise Physiol.) 57:1202 1210, 1984. |
11. Raff H, Maselli J, and Reid IA. Correlation of plasma angiotensin II concentration and plasma renin activity during acute hypoxia in dogs. Clin. Exper. Pharmacol. Physiol. 12:91 94, 1985 |
12. Licko V and Raff H. Rate sensitivity of blood pressure to hypoxia. J. Theoretical Biol. 112:839 845, 1985. |
13. Raff H, Goldmann RW, and Kindwall EP. Adrenocortical sensitivity after acute carbon monoxide exposure in humans. Arch. Environ. Health 40:88 90, 1985. |
14. Raff H, Merrill D, Skelton M, Cowley, AW Jr. Control of ACTH and vasopressin in neurohypophysectomized conscious dogs. Am. J. Physiol. (Regulatory, Integrative Compar. Physiol.) 249:R281 R285, 1985. |
15. Raff H, Shinsako J, Wade CE, Keil LC and Dallman MF. Acute volume expansion decreases adrenocortical sensitivity to ACTH and angiotensin II. Am. J. Physiol. (Regulatory, Integrative. Compar. Physiol.) 249:R611 R616, 1985. |
16. Raff H, Sandri RB, and Segerson TP. Renin, ACTH, and adrenocortical function during hypoxia and hemorrhage in conscious rats. Am. J. Physiol. (Regulatory, Integrative. Compar. Physiol.) 250:R240 244, 1986 |
17. Raff H and Levy SA. Renin angiotensin aldosterone and ACTH cortisol control during acute hypoxemia and exercise in patients with chronic obstructive lung disease. Am. Rev. Respir. Dis. 133:396 399, 1986 |
18. Findling JW, Buggy BP, Segerson TP, and Raff H. Pneumocystis carinii complicating intermittent Cushing's syndrome. Wisc. Med. J. 85:23 25, 1986 |
19. Cogswell TL, Bernath GA, Raff H, Hoffmann RG, Klopfenstein HS. Total peripheral resistance during cardiac tamponade: adrenergic and angiotensin roles. Am. J. Physiol. (Regulatory, Integrative, Compar. Physiol.) 251:R916 R922, 1986 |
20. Raff H, Skelton M, Merrill D, and Cowley AW Jr. Vasopressin responses to corticotropin releasing factor and hyperosmolality in conscious dogs. Am. J. Physiol. (Regulatory, Integrative, Compar. Physiol.) 251:R1235 R1239, 1986. |
21. Raff H, and Chadwick CJ. Aldosterone responses to ACTH during hypoxia in conscious rats. Clin. Exper. Pharmacol. Physiol. 13:827 830, 1986 |
22. Findling JW, Korducki JM, Lahiri PK, Miller DD, and Raff H. Bilateral adrenal hemorrhage associated with heparin induced thrombocytopenia. Wisc. Med. J. 86:27 29, 1987. |
23. Findling JW, Waters VO, and Raff H. The dissociation of renin and aldosterone during critical illness. J. Clin. Endocrinol. Metab. 64:592 595. 1987 |
24. Findling JW, Adams AH, and Raff H. Selective hypoaldosteronism due to an endogenous impairment in angiotensin II production. New Engl. J. Med. 316:1632 1635, 1987 |
25. Raff H, Norton AJ, Flemma RJ, and Findling JW. Inhibition of the ACTH response to surgery in humans: interaction between dexamethasone and fentanyl. J. Clin. Endocrinol. Metab. 65:295 298, 1987. |
26. Raff H and Roarty H. Renin, ACTH, and aldosterone during acute hypercapnia and hypoxia in conscious rats. Am. J. Physiol. (Regulatory, Integrative, Compar. Physiol.) 254:R431 R435, 1988. |
27. Raff H, Merrill DC, Skelton MM, Brownfield MS, and Cowley AW Jr. Control of adrenocorticotropin secretion and adrenocortical sensitivity in neurohypophysectomized, conscious dogs: effect of acute and chronic vasopressin replacement. Endocrinology 122:1410 1418, 1988. |
28. Roarty H and Raff H. Renin response to graded hemorrhage in conscious rats. Clin. Exper. Pharmacol. Physiol. 15:373 378, 1988 |
29. Raff H. Evaluation of a blood sample/transfusion protocol in rats: blood gases, renin and ACTH. Am. J. Physiol. (Regulatory, Integrative, Compar. Physiol.) 255:R851 R854, 1988 |
30. Raff H, Flemma RJ, and Findling JW. Fast cortisol induced inhibition of the adrenocorticotropin (ACTH) response to surgery in humans. J. Clin. Endocrinol. Metab. 67:1146 1148, 1988 |
31. Nishijima MK, Breslow MJ, Raff H, and Traystman RJ. Regional adrenal blood flow during hypoxia. Am. J. Physiol. (Heart Circ. Physiol) 256:H94 H100, 1989. |
32. Raff H, Ball DL, Goodfriend TL. Low oxygen selectively inhibits aldosterone secretion from bovine adrenocortical cells in vitro. Am. J. Physiol. (Endocrinol. Metab.) 256:E640 E644, 1989 |
33. Raff H and Findling JW. Evaluation of a new immunoradiometric (IRMA) assay for ACTH in normal subjects and patients with Cushing's syndrome. Clin. Chem. 35:596 600, 1989. |
34. Raff H, Skelton MM, and Cowley AW Jr. Feedback control of vasopressin and corticotrophin secretion in conscious dogs: effect of hypertonic saline. J. Endocrinol. (Jubilee Edition) 122:41 48, 1989. |
35. Lewin RF, Raff H, Findling JW, Skelton MM, Cowley AW Jr, King JF, and Dorros G. Stimulation of atrial natriuretic peptide and vasopressin during percutaneous transluminal aortic valvuloplasty. Am. Heart J. 118:292 298, 1989 |
36. Breslow MJ, Ball TD, Miller CF, Raff H, and Traystman RJ. Adrenal blood flow and secretory relationships during hypoxia in anesthetized dogs. Am. J. Physiol. (Heart Circ. Physiol.) 257:H1458 H1465, 1989. |
37. Raff H, Findling JW, and Wong J. Short loop adrenocorticotropin feedback after ACTH 1 24 injection in man is an artifact of the immunoradiometric assay. J. Clin. Endocrinol. Metab. 69:678 680, 1989. |
38. Raff, H, Skelton MM, Cowley AW Jr. Cortisol inhibition of vasopressin and ACTH responses to arterial hypotension in conscious dogs. Am. J. Physiol. (Regulatory, Integrative, Compar. Physiol.) 258:R64 R69, 1990 |
39. Raff H. Renin response to hemorrhage in conscious rats: effect of acute reductions in hematocrit. Am. J. Physiol. (Regulatory, Integrative, Compar. Physiol.) 258:R487 R491, 1990. |
40. Griffen SC, Raff H. Vasopressin responses to hypoxia in conscious rats: interaction with water restriction. J. Endocrinol. 125:61 66, 1990. |
41. Raff H, Kohandarvish S. The effect of oxygen on aldosterone release from bovine adrenocortical cells in vitro: PO2 vs steroidogenesis. Endocrinology 127:682 687, 1990. |
42. Breslow MJ, Robin JR, Mandress TD, Racusen LC, Raff H, and Traystman RJ. Changes in adrenal O2 consumption during catecholamine secretion in anesthetized dogs. Am. J. Physiol. (Heart Circ. Physiol.) 259:H681 H688, 1990 |
43. Raff H, Findling JW. Aldosterone control in critically ill patients: ACTH, metoclopramide, and atrial natriuretic peptide. Crit. Care Med. 18:915 920, 1990. |
44. Wood CE, Kane C, Raff H. Peripheral chemoreceptor control of fetal renin responses to hypoxia and hypercapnia. Circ. Res. 67:722 732, 1990 |
45. Lewin RF, Raff H, Findling JW, Dorros G. Stimulation of atrial natriuretic peptide and vasopressin during retrograde mitral valvuloplasty. Am. Heart J. 120:1305 1310, 1990 |
46. Breslow MJ, Tobin JR, Kubos KL, Raff H, Traystman RJ. Effect of adrenal hypotension on elicited secretory activity in anesthetized dogs. Am. J. Physiol. (Heart Circ. Physiol.) 260:H 21 26, 1991. |
47. Raff H, Papanek PE, Cowley AW Jr. ACTH and vasopressin responses to insulin induced hypoglycemia in intact and neurohypophysectomized conscious dogs. Neuroendocrinology 53:85 90, 1991. |
48. Brickner RC and Raff H. Oxygen sensitivity of potassium and angiotensin II stimulated aldosteronogenesis. J. Endocrinol 129:43 48, 1991. |
49. Blaney J, Sothmann M, Raff H, Hart B, Horn T. Impact of exercise training on plasma adrenocorticotropin hormone response to a well learned vigilance task. Psychoneuroendocrinology 15:453 462, 1991. |
50. Raff H, Kane CA, Wood CE. Arginine vasopressin responses to hypoxia and hypercapnia in late gestation fetal sheep. Am. J. Physiol. (Regul. Integr. Comp. Physiol) 260:R1077 R1081, 1991. |
51. Mattson DL, Raff H, Roman RJ. Influence of angiotensin II on pressure natriuresis and renal hemodynamics in volume expanded rats. Am. J. Physiol. (Regul. Integr. Comp. Physiol) 260:R1200 R1209, 1991. |
52. Findling JW, Kehoe ME, Shaker JL, Raff H. Routine inferior petrosal sinus sampling in the differential diagnosis of ACTH dependent Cushing's syndrome: early recognition of the occult ectopic ACTH syndrome. J. Clin. Endocrinol. Metab. 73:408 413, 1991. |
53. Sakima NT, Breslow MJ, Raff H, Traystman RJ. Lack of coupling between adrenal cortical metabolic activity and blood flow in anesthetized dogs. Am. J. Physiol. (Heart Circ. Physiol.) 261:H410 H415, 1991 |
54. Raff H, Rossing MH, Doepker SK, Griffen SC. Vasopressin response to hemorrhage in the rat: effect of hypoxia and water restriction. Clin. Exp. Pharmacol. Physiol. 18:725 729, 1991. |
55. Brickner RC, Jankowski B, Raff H. The conversion of corticosterone to aldosterone is the site of the oxygen sensitivity of the bovine adrenal zona glomerulosa. Endocrinology 130:88 92, 1992 |
56. Raff H, Papanek PE, Cowley AW Jr. Effect of hypotension and hyperosmolality on vasopressin and ACTH responses to hypoglycemia in conscious dogs. Am. J. Physiol. (Regul Integr Comp. Physiol.) 263:R382 R388, 1992 |
57. Raff H and CE Wood. Effect of age and blood pressure on the heart rate, vasopressin and renin responses to hypoxia in fetal sheep. Am. J. Physiol. (Regul Integr Comp Physiol.) 263:R880 R884, 1992 |
58. Goodfriend TL, Ball DL, Elliott ME, Chabhi A, Duong T, Raff H, Schneider EG, Brown RD, and Weinberger MH. Fatty acids may regulate aldosterone secretion and mediate some of insulin's effects on blood pressure. Prostaglandins, Leukotrienes, and Essential Fatty Acids 48:43 50, 1993. |
59. Raff H and Jankowski B. Effect of CO2/pH on the aldosterone response to hypoxia in bovine adrenal cells in vitro. Am. J. Physiol. (Regul. Integr. Comp. Physiol.) 265: R820-R825, 1993. |
60. Breslow MJ, Parker SD, Frank SM, Norris EJ, Yates H, Raff H, Rock P, Christopherson R, Rosenfeld BA, Beattie C, and the PIRAT Study Group. Determinants of catecholamine and cortisol responses to lower extremity revascularization and correlation with outcome variables. Anesthesiology 79:1202-1209, 1993. |
61. Ligier B, MJ Breslow, H Raff, and RJ Traystman. Adrenal blood flow and secretory effects of adrenergic receptor stimulation. Am. J. Physiol. (Heart and Circ. Physiol) 266:H220-H227, 1994 |
62. Raff H and Jankowski B. Inhibition of aldosterone release by hypoxia in vitro: interaction with carbon monoxide. J. Appl. Physiol. 76:689-693, 1994 |
63. Schwartz J, Ash P, Ford V, Raff H, Crosby S, and White A Secretion of adrenocorticotropin (ACTH) and ACTH precursors: actions of corticotropin releasing factor, arginine vasopressin and glucocorticoids. J. Endocrinol. 140:189-195, 1994. |
64. Papanek PE and Raff H. Physiological increases in cortisol inhibit basal vasopressin release in conscious dogs. Am. J. Physiol. (Regul. Integr. Comp. Physiol.) 266:R1744-R1751, 1994. |
65. Raff H, Shaker JL, Nelson DK, and Findling JW. Rapid measurement of corticotropin (ACTH) using a modified immunochemiluminescent assay. Clinical Chemistry 40:1344, 1994. |
66. Raff H, Papanek PE, Liard J-F, and Cowley, AW Jr. The effect of intracarotid vasopressin infusion on ACTH release in neurohypophysectomized, conscious dogs. Am. J. Physiol. (Regul. Integr Comp. Physiol.) 267:R653-R658, 1994 |
67. Papanek PE and Raff H. Chronic physiological increases in cortisol inhibit the vasopressin response to hypertonic saline in conscious dogs. Am. J. Physiol. (Regul. Integr Comp. Physiol) 267:R1342-R1349, 1994. |
68. Kay J, Findling JW, and Raff H. Epidural triamcinolone suppresses the pituitary adrenal axis in human subjects. Anesthesia and Analgesia 79:501-505, 1994. |
69. Findling JW, Buggy BP, Gilson IH, Brummitt CF, Bernstein BM, and Raff H. Longitudinal evaluation of adrenocortical function in patients with the human immunodeficiency virus. J. Clin. Endocrinol. Metab. 79:1091-1096, 1994. |
70. Heimler I, Rawlins RG, Binor Z, Aiman J, Raff H, and Hutz RJ. Elevated follicular fluid angiotensin II and pregnancy outcome. Fertility and Sterility 63: 528-534, 1995. |
71. Frank SM, Higgins MS, Breslow MJ, Fleisher LA, Gorman RB, Sitzmann JV, Raff H, and Beattie C. The catecholamine, cortisol, and hemodynamic responses to mild perioperative hypothermia. Anesthesiology 82:83-93, 1995 |
72. Raff H, Shaker JL, Seifert PE, Werner PH, Hazelrigg SR, and Findling JW. Intraoperative measurement of adrenocorticotropin (ACTH) during removal of ACTH-secreting bronchial carcinoid tumors. J. Clin. Endocrinol. Metab. 80:1036-1039, 1995. |
73. Raff H and Jankowski B. Oxygen dependence of pregnenolone and aldosterone synthesis in mitochondria isolated from bovine zona glomerulosa cells. J. Appl. Physiol. 78:1625-1628, 1995. |
74. Parker SD, Breslow MJ, Frank SM, Rosenfeld BA, Norris EJ, Christoperson R, Rock P, Gottlieb S, Raff H, et al. and the PIRAT Study Group. Catecholamine and cortisol responses to lower extremity revascularization: correlation with outcome variables. Critical Care Medicine 23:1954-1961, 1995 |
75. Shaker JL, Brickner RC, Divgi AB, Raff H, and Findling JW. Case report: renal phosphate wasting, syndrome of inappropriate antidiuretic hormone, and ectopic corticotropin production in small cell carcinoma. Am. J. Med. Sci. 310:38-41, 1995. |
76. O'Shaughnessy IM, Raff H, Findling JW. Factitious Cushing's syndrome: discovery with the use of a sensitive immunoradiometric assay for ACTH. Endocrine Practice 1:327-329, 1995. |
77. Oaks MK and Raff H. Differentiation of the expression of aldosterone synthase and 11-hydroxylase mRNA in the rat adrenal cortex by reverse transcriptase/polymerase chain reaction. J. Steroid. Biochem. Molecul. Biol. 54:193-199, 1995. |
78. Raff H, Papanek PE, and Cowles VE. Vasopressin responses to corticotropin-releasing factor and hypertonicity after truncal vagotomy in dogs. Am. J. Physiol. (Regulatory Integrative Comparative. Physiol) 270:R94-R98, 1996. |
79. Raff H, Jankowski BM, Engeland WC, and Oaks MK. Hypoxia in vivo inhibits aldosterone synthesis and aldosterone synthase mRNA in the rat. J. Appl. Physiol. 81:604-610, 1996. |
80. Papanek PE, Jankowski BM, and Raff H. Aldosterone release from adrenal cells is inhibited by hypoxia in vitro during maturation in rabbits. Reproduction, Fertility and Development 8:1131-1136, 1996 |
81. Papanek PE, Sladek CD, and Raff H. Corticosterone inhibition of osmotically-stimulated vasopressin from hypothalamic-neurohypophysial explants. Am. J. Physiol. (Regulatory Integrative Comparative Physiol.) 272:R158-R162, 1997 |
82. Frank SM, Higgins MS, Fleisher LA, Sitzmann J, Raff H, and Breslow MJ. The adrenergic, respiratory, and cardiovascular effects of core cooling in humans. Am. J. Physiol (Regulatory Integrative Comparative Physiology) 272:R557-R562, 1997. |
83. Raff H, Jankowski BM, Goodfriend TL, Baker JE, Papanek PE. The effect of exposure to hypoxia from birth on aldosterone in rabbits: role of unesterified fatty acids. Am. J. Physiol (Regulatory Integrative Comparative Physiol) 272:R1084-R1087, 1997. |
84. Findling JW, Raff H, Hansson JH, Lifton RP. Liddle's syndrome: prospective genetic screening and suppressed aldosterone secretion in an extended kindred. J. Clin. Endocrinol. Metab. 82:1071-1074, 1997. |
85. Graham KE, Raff H, Cook DM, Barnwell TL, Samuels MH. Intraoperative adrenocorticotropin levels during transsphenoidal surgery for Cushing's Disease does not predict cure. J. Clin. Endocrinol. Metab. 82:1776-1779, 1997. |
86. Aron DC, Raff H, Findling JW. Effectiveness versus efficacy: the limited value in clinical practice of high dose dexamethasone suppression testing in the differential diagnosis of ACTH-dependent Cushing's syndrome. J. Clin. Endocrinol. Metab. 82:1780-1785, 1997. |
87. Findling JW, Pinkstaff SM, Shaker JL, Raff H, Nelson JC. Pseudohypercortisoluria: spurious elevation of urinary cortisol due to carbamazepine. The Endocrinologist 8:51-54, 1998. |
88. Raff H, Raff JL, Findling JW. Late-night salivary cortisol as a screening test for Cushing's syndrome. J Clin. Endocrinol. Metab. 83:2681-2686, 1998 |
89. Raff H, Jankowski BM, Bruder ED, Engeland WC, Oaks MK. The effect of hypoxia from birth on the regulation of aldosterone in the 7-day-old rat: plasma hormones, steroidogenesis in vitro, and steroidogenic enzyme mRNA. Endocrinology 140:3147-3153, 1999 |
90. Raff H, Raff JL, Duthie EH, Wilson CR, Sasse EA, Rudman I, Mattson D. Elevated salivary cortisol in the evening in healthy elderly men and women: correlation with bone mineral density. J. Gerontol.: Med. Sci 54A: M479-M483, 1999. |
91. Raff H, Bruder ED, Jankowski BM. The effect of hypoxia on plasma leptin and insulin in newborn and juvenile rats. Endocrine 11: 37-39, 1999. |
92. Raff H, Bruder ED, Jankowski BM, Goodfriend TL. Neonatal hypoxic hyperlipidemia in the rat: effects on aldosterone and corticosterone synthesis in vitro. Am. J. Physiol. Regul. Integr. Comp. Physiol. 278:R663-R668, 2000. |
93. Raff H, Bruder ED, Jankowski BM, Engeland WC. The effect of fetal hypoxia on adrenocortical function in the 7-day old rat. Endocrine 13:111-116, 2000. |
94. Lee PC, Jelinek B, Struve M, Bruder ED, Raff H. Effect of neonatal hypoxia on the development of hepatic lipase in the rat. Am. J. Physiol. Regul. Integr. Comp. Physiol. 279:R1341-R1347, 2000. |
95. Whitcomb JE, Findling JW, Raff H, Harnsher K. Randomized trial of oral hydrocortisone and its effect on emergency physicians during night duty. Wisc Med J 99:37-41, 2000. |
96. Magill SB, Raff H, Shaker JL, Brickner RC, Knechtges TE, Kehoe ME, Findling JW. Comparison of adrenal vein sampling and computer tomography in the differentiation of primary aldosteronism. J. Clin. Endocrinol. Metab. 86:1066-1071, 2001 |
97. Raff H, Bruder ED, Jankowski BM, Colman J. Effect of neonatal hypoxia on leptin, insulin, growth hormone and body composition in the rat. Horm. Metab. Res. 33:151-155, 2001. |
98. Hjertstedt J, Burns EA, Fleming R, Raff H, Rudman I, Duthie EH, Wilson CR. Mandibular and palatal tori, bone mineral density and salivary cortisol in community dwelling elderly men and women. J. Gerontol. - Biol. Sci. & Med. Sci. 56:M731-5, 2001 |
99. Casale TB. Nelson HS. Stricker WE. Raff H. Newman KB. Suppression of hypothalamic-pituitary-adrenal axis activity with inhaled flunisolide and fluticasone propionate in adult asthma patients. Annals of Allergy, Asthma, & Immunology. 87:379-85, 2001 |
100. Raff H, Bruder ED, Jankowski B, Oaks MK, and Colman RJ. Growth hormone therapy during neonatal hypoxia in rats: body composition, bone mineral density, and IGF-1 expression. Endocrine 16:137-141, 2001 |
101. Raff H, Homar PJ, and Burns EA. Comparison of two methods for measuring salivary cortisol. Clinical Chemistry 48: 207-208, 2002. |
102. Bruder ED, Nagler AK, and Raff H. O2-dependence of ACTH-stimulated aldosterone and corticosterone synthesis in the rat adrenal cortex: developmental aspects. J. Endocrinol. 172:595-604, 2002 |
103. Nelson HS. Stricker W. Casale TB. Raff H. Fourre JA. Aron DC. Newman KB. A comparison of methods for assessing hypothalamic-pituitary-adrenal (HPA) axis activity in asthma patients treated with inhaled corticosteroid. J. Clin. Pharmacol. 42:319-26, 2002 |
104. Raff H. Effect of hypoxia on parathyroid hormone in lactating and neonatal rats: interaction with halothane. Endocrine 17:157-160, 2002. |
105. Lee PC, Struve M, Lewis SM, and Raff H. Neonatal hypoxia in the rat: effects on exocrine pancreatic development. J. Pediatric Gastroenterology and Nutrition 34:542-547, 2002. |
106. Raff H, Hong JJ, Oaks MK, and Widmaier EP. Adrenocortical responses to ACTH in the neonatal rat: The effect of hypoxia from birth on corticosterone, StAR, and PBR. Am J Physiol Regul Integr Comp Physiol 284:R78-R85. 2003. |
107. Raff H, Homar PJ, Skoner DP. A new enzyme immunoassay for salivary cortisol. Clin Chem 49:203-204, 2003. |
108. Goodfriend TL, Ball DL, Raff H, Bruder ED, Gardner HW, Spiteller G. Oxidized products of linoleic acid stimulate adrenal steroidogenesis. Endocrine Research 28:325-330, 2003. |
109. Lee PC, Struve M, Raff H. Effects of hypoxia on the development of intestinal enzymes in neonatal and juvenile rats. Exper. Biol. Med. 228:717-723, 2003. |
110. Bruder ED, Ball DL, Goodfriend TL, and Raff H. An oxidized metabolite of linoleic acid stimulates corticosterone production by rat adrenal cells. Am J Physiol Regul Integr Comp Physiol 284:R1631-R1635, 2003. |
111. Raff H. Total and active ghrelin in developing rats during hypoxia. Endocrine 21:159-161, 2003 |
112. Raff H, Jacobson L, Cullinan WE. Elevated corticosterone and inhibition of ACTH responses to CRH and ether in the neonatal rat: effect of hypoxia from birth. Am J Physiol Regul Integr Comp Physiol 285:R1224-R1230, 2003. |
113. Raff H, Lee JJ, Widmaier EP, Oaks MK, Engeland WC. Basal and ACTH-stimulated corticosterone in the neonatal rat exposed to hypoxia from birth: modulation by chemical sympathectomy. Endocrinology 145:79-86, 2004. |
114. Findling JW, Raff H, Aron DC. The low-dose dexamethasone suppression test: a re-evaluation in patients with Cushing's syndrome. J. Clin. Endocrinol. Metab. 89:1222-1226,2004. |
115. Bruder ED, Lee PC, Raff H. Metabolomic analysis of adrenal lipids during hypoxia in the neonatal rat: implications in steroidogenesis. Am J Physiology Endocrinol Metab 286:E697-E703, 2004. |
116. Bruder ED, Lee PC, Raff H. Metabolic consequences of hypoxia from birth and dexamethasone treatment in the neonatal rat: comprehensive hepatic lipid and fatty acid profiling. Endocrinology 145:5364-5372, 2004. |
117. Findling JW, Kehoe ME, Raff H. Identification of patients with Cushing's disease with negative pituitary adrenocorticotropin (ACTH) gradients during inferior petrosal sinus sampling: prolactin as an index of pituitary venous effluent. J Clin Endocrinol Metab 89:6005-6009, 2004. |
118. Bruder ED, Lee PC, Raff H. Lipid and fatty acid profiles in the brain, liver, and stomach contents of neonatal rats: effects of hypoxia. Am J Physiol Endocrinol Metab 288:E314-E320, 2005 |
119. Bruder ED, Lee PC, Raff H. Dexamethasone treatment in the newborn rat: fatty acid profiling of lung, brain, and serum lipids. J Appl Physiol 98: 981-990, 2005 |
120. Bruder ED, Jacobson L, Raff H. Plasma leptin and ghrelin in the neonatal rat: interaction of dexamethasone and hypoxia. J. Endocrinol. 185:477-484, 2005. |
121. Raff H. Teaching glucocorticoid negative feedback and adrenocortical regulation using a classic paper by Dwight Ingle. Adv Physiol Educ 29: 141-143, 2005 |
122. Liu H, Bravata DM, Cabaccan J, Raff H, Ryzen E. Elevated late-night salivary cortisol levels in elderly male type 2 diabetic veterans. Clinical Endocrinology 63:642-649, 2005. |
123. Raff H, Bruder ED, and the St. Luke's Medical Center Adrenal Tumor Study Group. Steroidogenesis in human aldosterone-secreting adenomas and adrenal hyperplasias: effects of hypoxia in vitro. Am J Physiol Endocrinol Metab 290:E199-E203, 2006. |
124. Raff H, Bruder ED. Adiponectin and resistin in the neonatal rat: effects of dexamethasone and hypoxia. Endocrine 29:341-344, 2006. |
125. Reeder DM, Raff H, Kunz TH, Widmaier EP. Characterization of pituitary-adrenocortical activity in the Malayan Flying Fox (Pteropus vampyrus). J Compar Physiol - B, Biochem, Systemic, & Environ Physiol. 176:513-519, 2006 |
126. Wilkinson CW, Raff H. Comparative evaluation of a new immunoradiometric assay for corticotropin. Clinical Chemistry and Laboratory Medicine 44:669-671, 2006 |
127. Bruder ED, Henderson LM, Raff H. Adrenal lipid profiles of chemically sympathectomized normoxic and hypoxic neonatal rats. Horm Metab Res 38:807-811, 2006. |
128. Bruder ED, Raff H, Goodfriend TL. An oxidized derivative of linoleic acid stimulates dehydroepiandrosterone production by human adrenal cells. Horm Metab Res 38:803-806, 2006. |
129. Kidambi S, Kotchen JM, Grim CE, Raff H, Mao J, Singh RJ, Kotchen TA. Association of adrenal steroids with hypertension and the metabolic syndrome in African Americans. Hypertension 49:704-711, 2007. |
130. Raff H, Jacobson L. Glucocorticoid feedback control of corticotropin (ACTH) in the hypoxic neonatal rat. J. Endocrinol. 192:453-458, 2007 |
131. Bruder ED, Lee JJ, Widmaier EP, Raff H. Microarray and real-time PCR analysis of adrenal gland gene expression in the 7-day-old rat: effects of hypoxia from birth. Physiol Genomics 29:193-200, 2007. |
132. Usa K, Singh RJ, Netzel BC, Liu Y, Raff H, Liang M. Renal interstitial corticosterone and 11-dehydrocorticosterone in conscious rats. Am J Physiol Renal Physiol 293:F186-F192, 2007. |
133. Raff H, Jacobson L, Cullinan WE. Augmented hypothalamic corticotrophin-releasing hormone mRNA and corticosterone responses to stress in adult rats exposed to perinatal hypoxia. J. Neuroendocrinol. 19:907-912, 2007 |
134. Kidambi S, Raff H, Findling JW. Limitations of nocturnal salivary cortisol and urine free cortisol in the diagnosis of mild Cushing's syndrome. Eur J Endocrinol 157:725-731, 2007. |
135. Woods DL, Kovach CR, Raff H, Basmadjian A, Hegadoren KM. Using saliva to measure endogenous cortisol in nursing home residents with advanced dementia. Research in Nursing & Health 31:283-194, 2008. |
136. Bruder ED, VanHoof J, Young JB, Raff H. Epidermal growth factor and parathyroid hormone-related peptide mRNA in the mammary gland and their concentrations in milk: effects of post-partum hypoxia in lactating rats. Horm Metab Res 40:446-453, 2008. |
137. Raff H. Immulite vs. Scantibodies IRMA Plasma ACTH (Peer Reviewed Letter to the Editor with data). Clinical Chemistry 54:1409-1410, 2008 |
138. Bruder ED, Taylor JK, Kamer KJ, Raff H. Development of the ACTH and corticosterone response to acute hypoxia in the neonatal rat. Am J Physiol Regul Integr Comp Physiol 295:R1195-R1203, 2008. |
139. Raff H. Brock S, Findling JW. Cosyntropin-stimulated salivary cortisol in hospitalized patients with hypoproteinemia. Endocrine 34:68-74, 2008. |
140. Carroll T, Raff H, Findling JW. Late-night salivary cortisol for the diagnosis of Cushing's syndrome: a meta-analysis. Endocrine Practice 15:335-342, 2009 |
141. Wade M, Baid S, Kalis K, Raff H, Sinaii N, Nieman L. Technical details influence the diagnostic accuracy of the 1 mcg ACTH stimulation test. Eur J Endocrinol 162:109-113, 2010 |
142. Bruder ED, Raff H. Cardiac and plasma lipid profiles in response to acute hypoxia in neonatal and young adult rats. Lipids in Health and Disease 9:3, 2010 (doi:10.1186/1476-511X-9-3) |
143. Bangaru MLY, Woodliff J, Raff H, Kansra S. Growth suppression of mouse pituitary corticotroph tumor AtT20 cells by curcumin: a model for treating Cushing's disease. PloS One 5:e9893, 2010 published 13 Apr 2010 | 10.1371/journal.pone.0009893 |
144. Cohen EP, Bruder ED, Cullinan WE, Ziegler D, Raff H. The effect of high dose total body irradiation on ACTH, corticosterone, and catecholamines in the rat. Translational Research 157:38-47, 2011 |
145. Kovach CR, Woods DL, Logan BR, Raff H. Diurnal variation of cortisol in people with dementia: relationship to cognition and illness burden. American Journal of Alzheimers Disease & Other Dementias 26:145-150, 2011 |
146. Bruder ED, Kamer KJ, Guenther MA, Raff H. Adrenocorticotropic hormone and corticosterone responses to acute hypoxia in the neonatal rat: effects of body temperature maintenance. Am J Physiol Regul Integr Comp Physiol 300:R708-R715, 2011. |
147. Raff H, Bruder ED, Cullinan WE, Ziegler D, Cohen EP. Effect of animal facility construction on basal hypothalamic-pituitary-adrenal and renin-aldosterone activity in the rat. Endocrinology 152:1218-1221, 2011. |
148. Raff H, Ettema SL, Eastwood DC, Woodson BT. Salivary cortisol in obstructive sleep apnea: the effect of CPAP. Endocrine Online First, 25 April 2011 DOI 10:1007/s12020-011-9474-1. |
149. Valentine AR, Raff H, Liu H, Ballesteros M, Rose JM, Jossart GH, Cirangle P, Bravata DM. Salivary Cortisol Increases After Bariatric Surgery in Women. Horm Metab Res (in press). |
150. Sharma ST, Raff H, Nieman LK. Prolactin as a marker of successful catheterization during IPSS in patients with ACTH-dependent Cushing’s Syndrome. J Clin Endocrinol Metab 96: 3687–3694, 2011. |
151. Guenther MA, Bruder ED, Raff H. Effects of body temperature maintenance on glucose, insulin, and corticosterone responses to acute hypoxia in the neonatal rat. Am J Physiol Regul Integr Comp Physiol 302:R627-R633, 2012 |
152. Kovach CR, Simpson MR, Joosse L, Logan BR, Noonan PE, Reynolds SA, Raff H. Comparison of the effectiveness of two protocols for treating nursing home residents with advanced dementia. Research in Gerontological Nursing 5:251-63, 2012. |
153. Raff H, Singh RJ. Measurement of late night salivary cortisol and cortisone by liquid chromatography – tandem mass spectrometry to assess pre-analytical sample contamination with topical hydrocortisone. Clinical Chemistry 58:947-948, 2012. |
154. Raff H, Trivedi H. Circadian rhythm of salivary cortisol, plasma cortisol, and plasma ACTH in end-stage renal disease. Endocr Connect 1: 134–142, 2012
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155. Caprirolo G, Ghanayem NS, Murkowski K, Nugent ML, Simpson PM, Raff H. Circadian rhythm of salivary cortisol in infants with congenital heart disease. Endocrine 43:214-218, 2013 |
156. Chintamaneni L. Bruder ED, Raff H. Effects of age on ACTH, corticosterone, glucose, insulin, and mRNA levels during intermittent hypoxia in the neonatal rat. Am J Physiol Regul Integr Comp Physiol 304:R782-R789, 2013. |
157. Johnson K, Bruder ED, Raff H. Adrenocortical control in the neonatal rat: ACTH- and cAMP-independent corticosterone production during hypoxia. Physiol Rep, 1 (3), 2013, e00054, doi: 10.1002/phy2.54. |
158. Kovach CR, Woods DL, Devine EC, Logan BR, Raff H. Biobehavioral measures as outcomes: a cautionary tale. Res Gerontol Nurs 7:56-65, 2014. |
159. Roberts CR, Stuhr KL, Hutz MJ, Raff H, Hillard CJ. Endocannabinoid signaling in HPA axis recovery following restraint stress: effects of indirect agonists and comparison of male and female mice. Pharmacology, Biochemistry and Behavior 117: 17–24, 2014 |
160. Chintamaneni K, Bruder ED, and Raff H. Programming of the hypothalamic-pituitary-adrenal axis by neonatal intermittent hypoxia: effects on adult male ACTH and corticosterone responses are stress-specific. Endocrinology 155: 1763–1770, 2014 |
161. Bodager J, Gessert T, Bruder ED, Gehrand A, Raff H. Adrenocortical sensitivity to ACTH in neonatal rats: correlation of corticosterone responses and adrenal cAMP content. Am J Physiol Regul Integr Comp Physiol 307: R347–R353, 2014. |
162. Dalmar A, Raff H, Chauhan SP, Singh M, Siddiqui DS. Serum 25-hydroxyvitamin D, calcium and calcium-regulating hormones in preeclamptics and controls during first day postpartum. Endocrine 79:44-48, 2014 |
163. Raff H, Gehrand A, Bruder ED, Hoffman MJ, Engeland WC, Moreno C. The renin knockout rat: control of adrenal aldosterone and corticosterone synthesis in vitro and adrenal gene expression. Am J Physiol Regul Integr Comp Physiol 308: R73–R77, 2015. – Chosen for APSselect – February, 2015 |
164. Trivedi H, Szabo A, Zhao S, Cantor T, Raff H. Circadian variation of mineral and bone parameters in end-stage renal disease. J. Nephrol. ePub DOI 10.1007/s40620-014-0124-6. 28:351-359, 2015. |
165. Gehrand AL, Kaldunski ML, Bruder ED, Jia S, Hessner MJ, Raff H. Intermittent neonatal hypoxia elicits the upregulation of inflammatory-related genes in adult male rats through long-lasting programming effects. Physiol Rep, 3 (12), 2015, e12646, doi: 10.14814/phy2.12646 |
166. Nensey NK, Bodager J, Gehrand AL, Raff H. Effect of novel melanocortin type 2 receptor (MC2R) antagonists on the corticosterone response to ACTH in the neonatal rat adrenal gland in vivo and in vitro. Front. Endocrinol. 7:23, 2016. doi:10.3389/fendo.2016.00023 |
167. Venkatesan T, Zadvornova Y, Raff H, Hillard CJ. Endocannabinoid-related lipids are increased during an episode of cyclic vomiting syndrome. Neurogastroenterol Motil 28:1409–1418, 2016 |
168. Gehrand AL, Hoeynck B, Jablonski M, Leonovicz C, Ye R, Scherer PE, Raff H. Sex differences in adult rat insulin and glucose responses to arginine: programming effects of neonatal separation, hypoxia, and hypothermia. Physiol Rep 4 (18), 2016, e12972, doi: 10.14814/phy2.12972 |
169. Raff H, Biru N, Reisinger N, Kramer D. Dissociation of ACTH and cortisol in septic and non-septic ICU patients. Endocrine 55:307–310, 2017 |
170. Raff H, Kramer DJ, Hillard CJ. Increase in the circulating endocannabinoid 2-arachidonoylglycerol is associated with gabapentin use in septic ICU patients. Endocrine 58:203–204, 2017 |
171. Raff H, Hoeynck B, Jablonski M, Leonovicz C, Phillips JM, Gehrand AL. Insulin sensitivity, leptin, adiponectin, resistin, and testosterone in adult male and female rats after maternal-neonatal separation and environmental stress. Am J Physiol Regul Integr Comp Physiol 314:R12-R21, 2018. Chosen for APSselect – November, 2017 |
172. Goldenberg AJ, Gehrand AL, Waples E, Jablonski M, Hoeynck B, Raff H. Effect of a melanocortin type 2 receptor (MC2R) antagonist on the corticosterone response to hypoxia and ACTH stimulation in the neonatal rat. Am J Physiol Regul Integr Comp Physiol 315:R128-R133, 2018. |
173. Gehrand AL, Hoeynck B, Jablonski M, Leonovicz C, Cullinan WE, Raff H. Programming of the adult HPA axis after neonatal separation and environmental stress in male and female rats. Endocrinology 159:2777-2789, 2018 |
174. Santen RK, Jewell CM, Yue W, Heitjan DF, Raff H, Katen KS, Cidlowski JA. Glucocorticoid receptor mutations and hypersensitivity to endogenous and exogenous glucocorticoids. J Clin Endocrinol Metab 103:3630–3639, 2018 |
175. Greene LW, Geer EB, Page-Wilson G, Findling JW, Raff H. Assay-specific spurious ACTH results lead to misdiagnosis, unnecessary testing, and surgical misadventure – a case series. Journal of the Endocrine Society, Volume 3, Issue 4, April 2019, Pages 763–772, https://doi.org/10.1210/js.2019-00027. •Top 10 percent of articles published in the journal in 2019-2020 as assessed by rate of citation. |
176. Gehrand AL, Phillips J, Malott K, Raff H. A long-acting neutralizing monoclonal ACTH antibody blocks corticosterone and adrenal gene responses in neonatal rats. Endocrinology 160:1719–1730, 2019. |
177. Raff H, Phillips JM. Bedtime salivary cortisol and cortisone by LC-MS/MS in healthy adult subjects: Evaluation of sampling time. Journal of the Endocrine Society, Volume 3, Issue 8, August 2019, Pages 1631–1640, https://doi.org/10.1210/js.2019-00186 |
178. Rolon S, Huynh C, Guenther M, Gardezi M, Phillips J, Gehrand AL, Raff H. The effects of flutamide on the neonatal rat hypothalamic-pituitary-adrenal and gonadal axes in response to hypoxia. Physiol Rep 2019;7:e14318. https://doi.org/10.14814/phy2.14318. |
179. Tjoe JA, Piacentine LB, Papanek PE, Raff H; Richards J, Harkins AL, Yin J, Ng AV. Team triathlon effects on physiological, psychological, and immunological measures in women breast cancer survivors. Support Care Cancer. 2020 Dec;28(12):6095-6104. doi: 10.1007/s00520-020-05457-2. Epub 2020 Apr 20. PMID: 32314053. |
180. Gehrand AL, Phillips J, Malott K, Raff H. Corticosterone, adrenal, and the pituitary-gonadal axis in neonatal rats: Effect of maternal separation and hypoxia. Endocrinology 161:1-14, 2020. https://doi.org/10.1210/endocr/bqaa085 |
181. Raff H, Phillips J, Simpson P, Weisman S, Hainsworth K. Serum soluble urokinase plasminogen activator receptor (suPAR) in adolescents: interaction of chronic pain and obesity. PAIN Reports: July/August 2020 - Volume 5 - Issue 4 - p e836 doi: 10.1097/PR9.0000000000000836 |
182. Kannankeril J, Carroll T, Findling JW, Javorsky B, Gunsolus IL, Phillips J, Raff H. Prospective evaluation of late-night salivary cortisol and cortisone by EIA and LC-MS/MS in suspected Cushing’s syndrome. Journal of the Endocrine Society, Volume 4, Issue 10, 1 October 2020, bvaa107, https://doi.org/10.1210/jendso/bvaa107 |
183. Rolon S, Huynh C, Guenther M, Gardezi M, Phillips J, Gehrand AL, Raff H. Insulin and glucose responses to hypoxia in male and female neonatal rats: effects of the androgen receptor antagonist flutamide. Physiol Rep. 2021; 9:e14663. https://doi.org/10.14814/phy2.14663 |
184. Javorsky BR, Raff H, Carroll TB, Algeciras-Schimnich A, Singh RJ, Colón-Franco JM, Findling JW. New cutoffs for the biochemical diagnosis of adrenal insufficiency after ACTH stimulation using specific cortisol assays. Journal of the Endocrine Society, Volume 5, Issue 4, April 2021, bvab022, https://doi.org/10.1210/jendso/bvab022. Featured Article week of March 29, 2021
Chosen for the Endocrine Society Thematic Issue on Adrenal Disease 2021 https://academic.oup.com/endocrinesociety/pages/thematic-issue-adrenal-disease-2021
Chosen for the Endocrine Society Thematic Issue on Rare Endocrine Diseases 2021
https://academic.oup.com/endocrinesociety/pages/thematic-issue-rare-endocrine-diseases-2021
Chosen by Doximity for inclusion in a: A Big Year for Endocrinology - 2021 Recap
Top 10 percent of articles published in the journal in 2020-2021, as assessed by rate of citation.
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185. Hainsworth K, Simpson P, Raff H, Grayson M, Zhang L, Weisman S. Circulating inflammatory biomarkers in adolescents: evidence of interactions between chronic pain and obesity. Pain Rep. 2021;6(1):e916. Published 2021 Apr 1. doi:10.1097/PR9.0000000000000916 |
186. Gehrand AL, Phillips J, Welhouse KD, Siddiqui H, Schulgit M, Hoffman J, Hunt H. Raff H. Glucocorticoid receptor antagonist alters corticosterone and receptor sensitive mRNAs in the hypoxic neonatal rat. Endocrinology, Volume 163, Issue 1, January 2022, bqab232, https://doi.org/10.1210/endocr/bqab232. PMID: 34791109. |
187. Gonzalez PA, Simcox J, Raff H, Wade G, Von Bank H, Weisman S, Hainsworth K. Lipid signatures of chronic pain in adolescents with and without obesity. Lipids Health Dis 21, 80 (2022). https://doi.org/10.1186/s12944-022-01690-2 |
188. Raff H, Phillips J, Simpson P, Weisman SJ, Hainsworth KR. Interaction of chronic pain, obesity and time of day on cortisol in female human adolescents. Stress, 25:1, 331-336, DOI: 10.1080/10253890.2022.2142778 |
189. Musacchio S, Kallenbach MD, Huber DL, Raff H, Johnson BD, Leddy J, McCrea MA, Meier TB. Nelson LD. Salivary cortisol dynamics after mild traumatic brain injury. Journal of Head Trauma Rehabilitation. ():10.1097/HTR.0000000000000855, January 21, 2023. | DOI: 10.1097/HTR.0000000000000855 |
190. Ferrari LF, Rey C, Ramirez A, Dziuba A, Zickella J, Zickella M, Raff H, Taylor NE. Characterization of the Dahl salt-sensitive rat as a rodent model of inherited, widespread, persistent pain. Sci Rep 12, 19348 (2022). https://doi.org/10.1038/s41598-022-24094-9 |
191. Raff H, Glaeser BL, Szabo A, Olsen CM, Everson CA. Sleep restriction during opioid abstinence affects the hypothalamic-pituitary-adrenal (HPA) axis in male and female rats. Stress epub 3/1/2023, DOI: 10.1080/10253890.2023.2185864 |
Books, Chapters, and Reviews |
1. Fitzgerald RS, Raff H, Garger P , Anand A, and Said SI. Vasoactive intestinal polypeptide (VIP) presence and action in the carotid body. In ADV. PHYSIOL. SCI., Volume 14, Endocrinology, Neuroendocrinology, Neuropeptides II. E Stark, GB Makara, B Halasz, Gy Rappay, eds. Pergamon Press, Elmsford, NY, 1981, pp 255 258. |
2. Fitzgerald RS, Raff H, Garger P, Fechter L, Anand A and Said SI. Vasoactive intestinal polypeptide (VIP) and the carotid body. In CHEMORECEPTION IN THE CAROTID BODY: Proceedings of the VIth International Meeting on Arterial Chemoreceptors. C Belmonte, DJ Pallot, H Acker and S Fidone, eds. Leicester University Press, 1981, pp 289 298. |
3. Raff H. Glucocorticoid Inhibition of Neurohypophyseal Vasopressin Secretion. Am. J. Physiol (Regulatory, Integrative, Compar. Physiol.) 252:R635 R644, 1987 |
4. Raff H. Interactions between vasopressin and the CRF ACTH adrenocortical control system. In: VASOPRESSIN: CELLULAR AND INTEGRATIVE FUNCTIONS. A.W. Cowley, Jr., J F Liard, and D.A. Ausiello, editors. Raven Press, New York: 1988, p363 369. |
5. Findling JW, Engeland WC, Raff H. The use of immunoradiometric assay for the measurement of ACTH in human plasma. Trends in Endocrinology and Metabolism 1:283 287, 1990. |
6. Raff H. The renin angiotensin aldosterone system during hypoxia. In: RESPONSE AND ADAPTATION TO HYPOXIA ORGAN TO ORGANELLE. S. Lahiri, N. Cherniak, and R.S. Fitzgerald, editors. Oxford University Press (American Physiological Society), New York: 1991, p211 222 |
7. Raff, H., R.C. Brickner, and B. Jankowski. The renin angiotensin aldosterone system during hypoxia: Is the adrenal an oxygen sensor? In: HYPOXIA AND MOUNTAIN MEDICINE. edited by J.R. Sutton, G. Coates, and C.S. Houston, Advances in the Biosciences, Vol. 84. Pergamon Press: Oxford and New York, 1992, p42 49. |
8. Raff H. Interactions between neurohypophyseal hormones and the ACTH adrenocortical axis. In: THE NEUROHYPOPHYSIS: A WINDOW ON BRAIN FUNCTION. Edited by W.G. North, A.M. Moses, and L. Share. New York Academy of Sciences, New York: 1993, p411 425. |
9. Findling JW and Raff H. Chapter 35: Ectopic ACTH. In: ENDOCRINE TUMORS. Mazzaferri EL and Samaan NA, eds. Blackwell Scientific Publications, Cambridge, 1993, p554-566. |
10. Raff H. Endocrine adaptation to hypoxia. In: HANDBOOK OF PHYSIOLOGY, SECTION 4: Environmental Physiology Volume II. Edited by M.J. Fregly and C.M. Blatteis. American Physiological Society - Oxford University Press, New York, 1996, p1259-1275. |
11. Raff, H. PHYSIOLOGY SECRETS. Hanley & Belfus, Philadelphia, 1998, 346 pages |
12. Raff H. Endocrine Physiology. In: PHYSIOLOGY SECRETS. Raff H, ed. Hanley & Belfus, Phildelphia, 1998, p175-221. |
13. Raff H. Suppression of the hypothalamic-pituitary-adrenal axis and other systemic effects of inhaled corticosteroids in asthma. The Endocrinologist 8:9-14, 1998. |
14. Raff H. Salivary cortisol: a useful measurement in the diagnosis of Cushing's syndrome and the evaluation of the hypothalamic-pituitary adrenal axis. The Endocrinologist 10:9-17, 2000. |
15. Findling JW and Raff H. Diagnosis and differential diagnosis of Cushing's syndrome. Endocrinology and Metabolism Clinics of North America 30:729-747, 2001. |
16. Raff, H. PHYSIOLOGY SECRETS 2nd Edition. Hanley & Belfus, Philadelphia, 2003, 414 pages |
17. Findling JW and Raff H. Newer diagnostic techniques and problems in Cushing's disease. Endocrinology and Metabolism Clinics of North America 28:191-210, 1999. |
18. Raff H and Cullinan WE. Hypothalamus-neuroendocrinology. In: NEUROSCIENCE SECRETS. Wong-Riley M, ed. Hanley and Belfus, Philadelphia, 1999, p238-251 |
19. Raff H. Endocrine Physiology. In: PHYSIOLOGY SECRETS 2nd Edition. Raff H, ed. Hanley & Belfus, 2003, p199-244. |
20. Raff H and Shaker JL. Bone physiology. In: PHYSIOLOGY SECRETS 2nd Edition. Raff H, ed. Hanley & Belfus, 2003, p245-248. |
21. Raff H and Findling JW. A physiologic approach to the diagnosis of Cushing syndrome. Annals of Internal Medicine 138:980-991, 2003 |
22. Raff H. The role of salivary cortisol determinations in the diagnosis of Cushing's syndrome. Current Opinion in Endocrinology and Diabetes 11:271-275. 2004. |
23. Raff H. Neonatal dexamethasone therapy: short and long-term consequences. Trends Endo Metab 15:351-352, 2004. |
24. Widmaier EP, Raff H, Strang KT. Vander, Sherman, & Luciano's HUMAN PHYSIOLOGY: The Mechanisms of Body Function, 9th Edition, McGraw-Hill, Boston, 2004, 823 pages. |
25. Findling JW and Raff H (Guest Editors). CUSHING'S SYNDROME. Endocrinology and Metabolism Clinics of North America. Vol 34 Number 2 June 2005. |
26. Findling JW and Raff H. Screening and diagnosis of Cushing's syndrome. In: CUSHING'S SYNDROME. Endocrinology and Metabolism Clinics of North America. 34:385-402, 2005. |
27. Widmaier EP, Raff H, Strang KT. Vander's HUMAN PHYSIOLOGY: The Mechanisms of Body Function, 10th Edition, McGraw-Hill, Boston, 2006, 827 pages. |
28. Findling JW and Raff H. Cushing's syndrome: important issues in diagnosis and management. J. Clin. Endocrinol. Metab 91:3746-3753, 2006 |
29. Rosner W, Auchus RJ, Azziz R, Sluss PM, Raff H. Utility, limitations and pitfalls in measuring testosterone: an Endocrine Society Position Statement. J. Clin. Endocrinol. Metab. 92:405-413, 2007 |
30. Findling JW, Raff H. Cushing's Disease: Diagnostic Evaluation. In: DIAGNOSIS AND MANAGEMENT OF PITUITARY DISORDERS. Swearingen B, Biller BMK, eds. Humana Press, Totowa NJ, 2008, p187-221. |
31. Raff H, Sluss PM. Pre-analytical issues for testosterone and estradiol assays. Steroids 73:1297-1304, 2008 |
32. Raff H. Cushing's syndrome: diagnosis using late-night salivary cortisol measurement. Clinical Laboratory International (CLI) 12:6-8, Dec 2008-Jan 2009 |
33. Carroll T, Raff H, Findling JW. Late-night salivary cortisol measurement in the diagnosis of Cushing's syndrome. Nature Clinical Practice Endocrinology & Metabolism 6:344-350, 2008. |
34. Widmaier EP, Raff H, Strang KT. Vander's HUMAN PHYSIOLOGY: The Mechanisms of Body Function, 11th Edition, McGraw-Hill, Boston, 2008, 770 pages. |
35. Widmaier EP, Raff H, Strang KT. Vander's HUMAN PHYSIOLOGY: The Mechanisms of Body Function, 12th Edition, McGraw-Hill, Boston, 2011, 754 pages. |
36. Raff H, Levitzky M. MEDICAL PHYSIOLOGY: A SYSTEMS APPROACH. McGraw-Hill Medical, New York, 2011, 786 pages. |
37. Raff H. Utility of salivary cortisol measurements in Cushing's syndrome and adrenal insufficiency. J Clin Endocrinol Metab 94:3647-3655, 2009 |
38. Widmaier EP, Raff H, Strang KT. Vander’s HUMAN PHYSIOLOGY: The Mechanisms of Body Function, 12th Edition, McGraw-Hill, New York, 2011, 754 pages. |
39. Raff H, Levitzky M. MEDICAL PHYSIOLOGY: A SYSTEMS APPROACH. McGraw-Hill Medical, New York, 2011, 786 pages. |
40. Widmaier EP, Raff H, Strang KT. Vander’s HUMAN PHYSIOLOGY: The Mechanisms of Body Function, 13th Edition, McGraw-Hill, New York, 2014, 800 pages. |
41. Raff H. Cushing’s syndrome: diagnosis and surveillance using salivary cortisol. Pituitary 15:64-70, 2012 |
42. Widmaier EP, Raff H, Strang KT. Vander’s HUMAN PHYSIOLOGY: The Mechanisms of Body Function, 14th Edition, McGraw-Hill, New York, 2016, 784 pages. |
43. Raff H. Update on late-night salivary cortisol for the diagnosis of Cushing’s Syndrome: methodological considerations. Endocrine 44:346–349, 2013
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44. Raff H, Sharma ST, Nieman LK. Physiological basis for the etiology, diagnosis and treatment of adrenal disorders: Cushing’s syndrome, adrenal insufficiency, and congenital adrenal hyperplasia. Compr Physiol 4:739-768, 2014 |
45. Raff H. Cushing Syndrome: Update on Testing. Endocrinol Metab Clin N Am 44:43–50, 2015 |
46. Raff H, Carroll T. Cushing’s syndrome: from physiological principles to diagnosis and clinical care. J. Physiol. (UK) 593:493–506, 2015. |
47. Findling JW, Raff H. Neoplastic/Pathological and Nonneoplastic/Physiological Hypercortisolism: Cushing Versus Pseudo-Cushing Syndromes. IN: THE HYPOTHALAMIC-PITUITARY-ADRENAL AXIS IN HEALTH AND DISEASE: CUSHING'S SYNDROME AND BEYOND. Gear, E, ed. Springer International Publishing, Switzerland, 2017, p111- 136. DOI 10.1007/978-3-319-45950-9_6 |
48. Findling JW, Raff H. Differentiation of Pathologic/Neoplastic Hypercortisolism (Cushing Syndrome) from Physiologic/Non-neoplastic Hypercortisolism (formerly known as Pseudo-Cushing Syndrome). European Journal of Endocrinology 176:R205–R216, 2017. |
49. Widmaier EP, Raff H, Strang KT. Vander’s HUMAN PHYSIOLOGY: The Mechanisms of Body Function, 15th Edition, McGraw-Hill, New York, 2019, 770 pages. |
50. Widmaier EP, Raff H, Strang KT. Vander’s HUMAN PHYSIOLOGY: The Mechanisms of Body Function, 16th Edition, McGraw-Hill, New York, 2023, 805 pages. |
51. Raff, H. Adrenal steroid biosynthesis. Post TW, ed. UpToDate. Waltham, MA: UpToDate Inc. http://www.uptodate.com. Accessed November 4, 2019; Updated December 17, 2019. |
52. Nieman LK, Raff H. Initial testing for adrenal insufficiency: Basal cortisol and the ACTH stimulation test. Post TW, ed. UpToDate. Waltham, MA: UpToDate Inc. http://www.uptodate.com. Accessed November 4, 2019. Updated September 8, 2022 |
53. Lacroix, A, Raff H. Desmopressin (DDAVP) stimulation test. Post TW, ed. UpToDate. Waltham, MA: UpToDate Inc. http://www.uptodate.com. Accessed November 4, 2019. |
54. Lacroix, A, Raff H. Metyrapone stimulation tests. Post TW, ed. UpToDate. Waltham, MA: UpToDate Inc. http://www.uptodate.com. Accessed November 4, 2019. |
55. Nieman LK, Raff H. Corticotropin-releasing hormone stimulation test. Post TW, ed. UpToDate. Waltham, MA: UpToDate Inc. http://www.uptodate.com. Accessed November 4, 2019. Last updated: Jun 07, 2021 |
56. Nieman LK, Raff H. Insulin-induced hypoglycemia test. Post TW, ed. UpToDate. Waltham, MA: UpToDate Inc. http://www.uptodate.com. Accessed November 4, 2019. |
57. Lacroix, A, Raff H. Dexamethasone suppression tests. Post TW, ed. UpToDate. Waltham, MA: UpToDate Inc. http://www.uptodate.com. Accessed April 3, 2020. |
58. Nieman LK, Raff H. Measurement of urinary excretion of endogenous and exogenous glucocorticoids. Post TW, ed. UpToDate. Waltham, MA: UpToDate Inc. http://www.uptodate.com. Accessed June 23, 2020. |
59. Fleseriu M, (Co-authors in alphabetic author) Auchus R, Bancos I, Ben-Shlomo A, Bertherat J, Biermasz NR, Boguszewski CL, Bronstein MD, Buchfelder M, Carmichael JD, Casanueva FF, Castinetti F, Chanson P, Findling J, Gadelha M, Geer EB, Giustina A, Grossman A, Gurnell M, Ho K, Ioachimescu AG, Kaiser UB, Karavitaki N, Katznelson L, Kelly DF, Lacroix A, McCormack A, Melmed S, Molitch M, Mortini P, Newell-Price J, Nieman, L Pereira AM, Petersenn S, Pivonello R, Raff H, Reincke M, Salvatori R, Scaroni C, Shimon I, Stratakis CA, Swearingen B, Tabarin A, Takahashi Y, Theodoropoulou M, Tsagarakis S, Valassi E, Varlamov EV, Vila G, Wass J, Webb SM, Zatelli MC, Biller BMK. Consensus on diagnosis and management of Cushing's disease: a guideline update. Lancet Diabetes Endocrinol. 2021 Dec;9(12):847-875. doi: 10.1016/S2213-8587(21)00235-7. Epub 2021 Oct 20. PMID: 34687601. |
60. Gadelha MR, Karavitaki N, Fudin J, Bettinger JJ, Raff H, Ben-Shlomo A. Opioids and pituitary function: expert opinion. Pituitary 2022 Feb;25(1):52-63. doi: 10.1007/s11102-021-01202-y. Epub 2022 Jan 23. PMID: 35066756. |
61. Raff H. Late night salivary cortisol in the diagnosis of neoplastic hypercortisolism (including cyclic Cushing’s syndrome). Pituitary Oct;25(5):698-700, 2022. doi: 10.1007/s11102-022-01214-2. Epub 2022 Mar 25. PMID: 35334030. |
62. Raff H, Straseski J, Keevil B. Principles of Endocrine Measurements (Chapter 3). DeGroot's Endocrinology: Basic Science and Clinical Practice. 8th Edition. Editor: R. Paul Robertson. Hardcover ISBN: 9780323694124 - November 3, 2022. Elsevier |
Editorials, Letters To Editor, Other |
1. Raff H. Renin angiotensin aldosterone system during acute hypoxemia (Letter to the Editor). J. Appl. Physiol. 59:1026, 1985. |
2. Findling JW and Raff H. Selective hypoaldosteronism and impairment of angiotensin II production. (Reply to Letter to the Editor). New Engl. J. Med. 317:1739 1740, 1987. |
3. Colice GL, Farber M, Rose CE, Raff H, and Ramirez G. Fluid balance in acute and chronic lung disease (Editorial). Am. Rev. Resp. Dis. 138:1052, 1988 |
4. Breslow MJ, Tobin JR, Kubos KL, Traystman RJ, and Raff H. Coupling of adrenal blood flow and secretion. (Reply to Letter to the Editor). Am J. Physiol. (Heart Circ. Physiol.) 30:H1351, 1991. |
5. Dawson, C.A., A.W. Cowley, Jr, G.B. Spurr, J.L. Osborn, H. Raff, et al. Performance on multiple choice/short answer tests is not a sufficient criterion for evaluating the educational value of live animal laboratories in the teaching of physiology. Am. J. Physiol. (Adv. Physiol. Educ.) 261:S34 S35, 1991. |
6. Raff H. Technical Notes: Immunoradiometric Assay. Endocrine News 19:6, 1994. |
7. Raff H, Shaker JL, Findling JW. Rapid ACTH immunochemiluminescence Assay. Nichols Institute Breakthrough 2:5-6, 1994 |
8. Raff H. What are the afferent mechanisms of hypotension-induced vasopressin release? News in Physiological Sciences 9:281, 1994 |
9. Samson WK and Raff H. Book Review: Grant Application Writer's Handbook. Endocrine News 21:6&8, 1996 |
10. Raff H. Clinical case conference as an adjunct to lectures in medical physiology. Advances in Physiology Education 17:S48-S49, 1997 |
11. Raff H. NIH post-doc experience. The Scientist, June 21, 1999, p 12 |
12. Raff H, Shaker JL, Magill SB, Kehoe ME, and Findling JW. PTHrp during petrosal sinus sampling. Clin Endocrinol 56:419-420, 2002. |
13. Raff H. A suggestion for the multiple author issue. Science 301: 55-57, 2003. |
14. Raff H. The significance of the blood gas analyzer. J Appl Physiol 97: 1597-1598, 2004 |
15. Raff H, Benos D, Reich M. Introduction to the classic papers commemorating the APS Legacy Project. J Appl Physiol 97: 1589-1590, 2004; Am J Physiol Heart Circ Physiol, 287: H1883-H1884, 2004; Am J Physiol Cell Physiol, 287: C1163-C1164, 2004, Am J Physiol Renal Physiol, 287: F859 - F860, 2004; Am J Physiol Endocrinol Metab, 287: E811 - E812, 2004; Am J Physiol Regulatory Integrative Comp Physiol 287: R1005 - R1006, 2004; Am J Physiol Lung Cell Mol Physiol, 287: L891 - L892, 2004; Am J Physiol Gastrointest Liver Physiol 287: G939 - G940, 2004. |
16. Raff H. Using classic papers to teach physiology. Advan. Physiol. Edu. 29:138, 2005 |
17. Raff H, Molthen R, Pan W, Kastin AJ. Commentaries on Viewpoint: Effect of altitude on leptin levels, does it go up or down? Control of leptin with altitude exposure J Appl Physiol 105: 1686-1687, 2008. |
18. Raff H, Findling JW. Salivary cortisol or cortisone? Nature Clinical Practice Endocrinology & Metabolism 6:658-660, 2010 |
19. Rosner W, Vesper H on behalf of The Endocrine Society (H Raff on committee). Toward excellence in testosterone testing: a consensus statement. J. Clin. Endocrinol. Metab. 95:4542-4548, 2010. |
20. Raff H. Salivary cortisol and the diagnosis of Cushing's syndrome: a coming of age. Endocrine 41:353–354, 2012 |
21. Raff H. The realities of salivary cortisol sampling in the real world: Reply to the Letter to the Editor from Belaya and Melnichenko. Endocrine 42:224-225, 2012 |
22. Raff H. Update on late-night salivary cortisol for the diagnosis of Cushing’s syndrome: methodological considerations. Endocrine 44:346–349, 2013 |
23. Raff H, Brown D. Civil, sensible, and constructive peer review in APS journals. Adv Physiol Educ 37:211-212, 2013; Am J Physiol Cell Physiol 305:C239-C240, 2013; Am J Physiol Gastrointest Liver Physiol 305:G205-G206, 2013; Am J Physiol Endocrinol Metab 305:E315-E316, 2013; Am J Physiol Renal Physiol 305:(3) F227-F228, 2013; Am J Physiol Heart Circ Physiol 305:H265-H266, 2013; Am J Physiol Lung Cell Mol Physiol 305:L203-L204, 2013; J Neurophysiol 110:573-574, 2013; Physiol. Genomics 45:629-630, 2013; Am J Physiol Regul Integr Comp Physiol 305:R171-R172, 2013; J Appl Physiol 115:295-296, 2013. |
24. Raff H, Auchus RJ, Findling JW, Nieman L. Urine free cortisol in the diagnosis of Cushing’s syndrome: Is it worth doing and, if so, how? J Clin Endocrinol Metab 100:395-397, 2015. |
25. Raff H. Measurement of salivary cortisol to assess the adequacy of hydrocortisone replacement. J Clin Endocrinol Metab 101:1350–1352, 2016. |
26. Raff H. News & Views: Do the effects of the triorganotin tributyltin on the hypothalamic-pituitary-adrenal axis in vivo contribute to its environmental toxicity? Endocrinology 157:2996–2998, 2016. |
27. Raff H. Commentary: CORT, Cort, B, corticosterone and now cortistatin: enough already! Endocrinology 57:3307–3308, 2016 |
28. Raff H and Magill SB. Is the hypothalamic-pituitary-adrenal axis disrupted in type 2 diabetes mellitus? Endocrine 54:273–275, 2016 |
29. Raff H and Magill SB. Is the hypothalamic-pituitary-adrenal axis disrupted in type 2 diabetes mellitus? Endocrine 54:273–275, 2016 |
30. Findling JW and Raff H. Response to Letter to the Editor: DIAGNOSIS OF ENDOCRINE DISEASE: Differentiation of Pathologic/Neoplastic Hypercortisolism (Cushing Syndrome) from Physiologic/Non-neoplastic Hypercortisolism (formerly known as Pseudo-Cushing Syndrome). Eur J. Endocrinol. 178:L3, 2018. |
31. Raff H, Cohen EP, Findling JW. Commentary - Diagnosing Cushing’s disease in the context of renal failure: A case report and literature review. European Journal of Endocrinology 181:C9–C11, 2019. |
32. Greene LW, Geer EB, Page-Wilson G, Findling JW, Raff H. Invited Response to Letter to the Editor: Assay-specific spurious ACTH results lead to misdiagnosis, unnecessary testing, and surgical misadventure—a case series. Journal of the Endocrine Society, Volume 4, Issue 2, February 2020, bvz012, https://doi.org/10.1210/jendso/bvz012. |
33. Javorsky BR, Raff H, Carroll TB, Algeciras-Schimnich A, Singh RJ, Colón-Franco JM, Findling JW. Response to Letter to the Editor from Jialal and Sood: New cutoffs for the biochemical diagnosis of adrenal insufficiency after ACTH stimulation using specific cortisol assays. Journal of the Endocrine Society, Volume 5, Issue 9, September 2021, bvab113, https://doi.org/10.1210/jendso/bvab113 |
34. Raff H. Remembering “a True Giant in Endocrinology and Neuroendocrinology,” Mary F. Dallman, PhD. Endocrine News January 2022. Endocrinenews.org. Endocrine eNews. January 5, 2022. https://endocrinenews.endocrine.org/remembering-a-true-giant-in-endocrinology-and-neuroendocrinology-mary-f-dallman-phd/ |
35. Medda R, Raff H, Shaker J, Guda N. Response to Grover et al., The American Journal of Gastroenterology: Am J Gastroenterol 2022;117:813–814. https://doi.org/10.14309/ajg.0000000000001636 |
36. Raff H, Zhang C. A New Approach: Home Waking Salivary Cortisone to Screen for Adrenal Insufficiency. NEJM Evidence. 2023;2(2):EVIDe2200306. |
Abstracts |
1. Fitzgerald RS, Hauer C, Raff H. The direct effect of CO2 on the diaphragm. The Physiologist 20:29, 1977 |
2. Fitzgerald RS, Hauer C, and Raff H. The direct effect of hypercapnea on the rat diaphragm. American Review of Respiratory Disease 117:335, 1978 |
3. Raff H, Garger P, Fechter LD, Tzankoff SP, and Fitzgerald RS. Adrenal responses to hypoxemia. Fed. Proc. 38:982, 1979 |
4. Raff H, Tzankoff SP, and Fitzgerald RS. Cortisol and ACTH responses to hypoxic and carbon monoxide hypoxia. Fed. Proc. 39:489, 1980 |
5. Fitzgerald RS, Raff H, Garger P, Anand A, and Said SI. Vasoactive intestinal polypeptide (VIP) and the carotid body. Fed. Proc. 39:594, 1980. |
6. Fitzgerald RS, Raff H, Garger P, Anand A, and Said SI. A role for vasoactive intestinal polypeptide (VIP) in the carotid body. Proc. Inter. Union of Physiol. Sci. 14:412, 1980 |
7. Fitzgerald RS, Garger P, Fechter L, Raff H, and Hauer C. Hypoxia, hypercapnea, and catecholamine release in the cat carotid body. The Physiologist 23:68, 1980 |
8. Raff H, Tzankoff SP, and Fitzgerald RS. The role of peripheral arterial chemoreceptors in the cortisol and ACTH responses to hypoxic hypoxia. Fed. Proc. 40:418, 1981 |
9. Raff H, Shinsako J, and Dallman MF. Surgery potentiates the ACTH and corticosteroid responses to hypoxia. Fed. Proc. 41:4915, 1982 |
10. Raff H and Shinsako J. Hypercapnia increases the ACTH and corticosteroid response to graded hypoxia. Endocrinology 110:383A, 1982 |
11. Raff H, Shinsako J, and Dallman MF. ACTH and corticosteroid responses to isocapnic hypoxia: the effect of the rate of change of PaO2. Fed. Proc. 43:726, 1983 |
12. Fitzgerald RS, Hauer MC, Bierkamper GG, Bassett DJP, and Raff H. Rat diaphragm response to unbuffered/buffered acidosis/alkalosis. Fed Proc. 43:1012, 1983 |
13. Raff H, Maselli J, and Reid IA. Plasma renin activity and angiotensin II concentration during hypoxia in dogs: evidence against converting enzyme inhibition. Fed. Proc. 43:271, 1984 |
14. Raff H, Shinsako J, Wade CE, Keil LC, and Dallman MF. Comparison of the stimulatory effects of ACTH and angiotensin II on aldosterone and corticosteroid levels in conscious dogs. 7th International Congress of Endocrinology. Excerpta Medica, Amsterdam. 1984, p1102. |
15. Segerson TP, Raff H, Katzoff MN, Levy SA and Findling JW. Intermittent Ectopic Cushing's sydrome: localization of an occult ACTH source by selective bronchial lavage for ACTH. 7th International Congress of Endocrinology. Excerpta Medica, Amsterdam. 1984, p1395. |
16. Raff H, TP Segerson, TJ Quirk, BA Pogacar, SA Feldmann, DE Beyerl, KK Livergood, DA Parworth, MN Katzoff, I Margolis, and SA Levy. Renin, angiotensin II, and aldosterone levels in patients with lung disease: the effects of hypoxia and exercise. Fed. Proc. 44:6787, 1985. |
17. Segerson TP, JW Findling, and H. Raff. Effect of indomethacin on potassium stimulated aldosterone secretion. Fed. Proc. 44:4613, 1985 |
18. Waters VO, Findling JW, and H. Raff. Correlation of angiotensin II and renin levels in critically ill patients. Fed. Proc. 44:6786, 1985. |
19. Waters VO, H. Raff, and J.W. Findling. Measurement of renin, angiotensin II, and aldosterone levels in critically ill patients. Critical Care Medicine 13:282, 1985 |
20. Raff, H, D. Merrill, M. Skelton, and AW Cowley. Neurohypophysectomy attenuates the ACTH response to hypotension but not to CRF in conscious dogs. Endocrinology 116:494A, 1985. |
21. Findling JW, VO Waters, TP Segerson, and H. Raff. Hyperreninemic hypoaldosteronism in the critically ill: evaluation of angiotensin II, ACTH, and potassium levels. Endocrinology 116:546A, 1985. |
22. Raff H, R. Sandri, and TP Segerson. Interaction of hemorrhage and hypoxia in the control of blood pressure, renin, ACTH, and adrenal function in conscious rats. The Physiologist 28:274, 1985 |
23. Cogswell TL, GA Bernath, H Raff, DM Peterson, DJ Janzer, and HS Klopfenstein. Elevations in total peripheral resistance during cardiac tamponade depend on both alpha adrenergic and renin angiotensin mechanisms. Circulation 72:III 354, 1985 |
24. Cogswell TL, GA Bernath, H Raff, DJ Janzer, DM Peterson, and HS Klopfenstein. Alpha adrenergic and renin angiotensin mechanisms modulate the increase in total peripheral resistance during cardiac tamponade. Clinical Research 33:802A, 1985 |
25. Roarty TP, KJ Chadwick, and H. Raff. Renin responses to hemorrhage in conscious rats. Federation Proceedings 45:186, 1986. |
26. Findling J, T Segerson, P Gotch, H Raff, T Schmahl, A Tector, A Tector III. Use of a continuous intravenous insulin infusion in 101 diabetic cardiac surgery patients. Diabetes 35 (Suppl #1):459, 1986 |
27. Raff H, D Merrill, M. Skelton, and AW Cowley, Jr. CRF induced increases in vasopressin and ACTH in conscious dogs are potentiated by an osmotic stimulus. Endocrinology 118:654A, 1986 |
28. Raff H, D. Merrill, M. Skelton, and A.W. Cowley, Jr. Vasopressin responses to CRF in conscious dogs. Proceedings of the International Union of Physiological Sciences 16:379, 1986. |
29. Klopfenstein HS, TL Cogswell, GA Bernath, and H. Raff. Humoral and adrenergic mechanisms modulate the increase in total peripheral resistance during acute cardiac tamponade in conscious dogs. Proceedings of the International Union of Physiological Sciences Volume 16:290, 1986. |
30. Cogswell TL, GA Bernath, H Raff, HS Klopfenstein. The role of humoral and adrenergic influences on total peripheral resistance during acute cardiac tamponade in conscious dogs. Clinical Research 34:290A, 1986. |
31. Raff H, D. Merrill, M. Skelton, and A.W. Cowley, Jr. Vasopressin responses to corticotropin releasing factor in conscious dogs: glucocorticoid suppression. Abstracts of the 1st International Congress of Neuroendocrinology. Neuroendocrinology: S. Karger: Basel. 1986. p44, abstract #85. |
32. Raff H, TL Cogswell, GA Bernath, and HS Klopfenstein. Vasopressin and ACTH responses to acute cardiac tamponade in conscious dogs. Clinical Research 34:899A, 1986 |
33. Findling JW, AH Adams, and H. Raff. Endogenous angiotensin II deficiency: A cause of selective hypoaldosteronism. Clinical Research 34:908A, 1986 |
34. Raff H, RJ Flemma, AJ Norton, JW Findling. Angiotensin II generation during cardiopulmonary bypass in humans. Federation Proceedings 46: 1266, 1987 |
35. Raff H, DK Nelson, AJ Norton, RJ Flemma, and JW Findling. Inhibition of the ACTH response to surgery in humans: corticosteroid fentanyl interaction. Endocrinology 120:486A, 1987. |
36. Raff H, MM Skelton, DC Merrill, and AW Cowley, Jr. Role of vasopressin in the ACTH response to hypotension in neurohypophysectomized, conscious dogs. Soc. Neurosci. Abstr. 13:1372, 1987 |
37. Findling J, M Kehoe, and H. Raff. Bilateral petrosal sinus ACTH sampling in Cushing's syndrome: early recognition of the occult ectopic ACTH syndrome. Clinical Research 35, 844A, 1987. |
38. Mattson DL, H Raff, and RJ Roman. Modulation of the pressure natriuresis relationship by angiotensin. 20th Annual Meeting Abstracts Am Soc Nephrology, 264A. |
39. Raff H, RF Lewin, MM Skelton, AW Cowley Jr, JW Findling, JF King, and G. Dorros. Transient aortic obstruction increases atrial natriuretic peptide and vasopressin but not renin levels in patients with heart failure. FASEB Journal 2:A307, 1988. |
40. Griffen SC, MM Skelton, and H Raff. Vasopressin levels during hypoxia in conscious, cannulated rats. FASEB Journal 2:A1483, 1988. |
41. Mattson DL, H Raff, and RJ Roman. Effects of captopril and angiotensin II (AII) on cortical and papillary blood flow in rats. FASEB Journal 2:A1272, 1988 |
42. Merrill DC, TJ Ebert, MM Skelton, H Raff, J Lemann Jr, and AW Cowley Jr. Angiotensin II sensitization of aldosterone responsiveness to plasma sodium in man. FASEB Journal 2:A1322, 1988. |
43. Raff H and Flemma RJ. Fast feedback inhibition of the ACTH response to surgery in humans. Endocrinology 122:918A, 1988. |
44. Diaz SD, Waters VO, Raff H, and Findling JW. Dissociation of renin and aldosterone in critical illness: responses to ACTH and metoclopramide. Endocrinology 122:123A, 1988. |
45. Raff H, Ball DL, and Goodfriend TL. The effect of hypoxia on aldosterone secretion in vitro. Clinical Research 36:835A, 1988. |
46. Raff H, Lewin RF, Skelton MM, Cowley AW Jr, Findling JW, King JF and Dorros G. Atrial septal puncture and mitral valve obstruction independently increase atrial natriuretic peptide in patients with congestive heart failure. FASEB J 3:A917, 1989. |
47. Griffen SC, Jankowski B, Skelton MM, and Raff H. Water restriction augments the vasopressin response to hypoxia in conscious cannulated rats. FASEB J 3:A245, 1989. |
48. Rossing MH, Griffen SC, and Raff H. Diffusion of oxygen and carbon dioxide through pump tubing. FASEB Journal 3:A274, 1989. |
49. Raff H, Findling JW, and Wong J. Ultra short loop inhibition of ACTH secretion after ACTH(1 24) administration in man cannot be detected by two site immunoradiometric assay. Abstract #1750 71st Endocrine Society Meeting, 1989 |
50. Findling JW, Shaker JL, Hanson JP, Engeland W, Graeber CT, Wong J, and Raff H. Clinical evaluation of a two site immunoradiometric assay for ACTH(1 39) in normal subjects and patients with pituitary adrenal disorders. Abstract #1749, 71st Endocrine Society Meeting, 1989. |
51. Wood CE and Raff H. Noninteraction of baroreceptors and chemoreceptors in the control of plasma renin activity responses to fetal hypoxia. The Physiologist 32:170, 1989. |
52. Wood CE and Raff H. Fetal chemoreceptor control of renin responses to hypercapnia and hypoxia. Circulation 80:II 469, 1989. |
53. Raff H, Brummitt C, Buggy B, Gilson I, McNamara M, and Findling J. Subnormal aldosterone responses to ACTH in patients with HIV infection. Clinical Research 37:897A, 1989 |
54. Raff H, Ball DL, and Goodfriend TL. Adrenal glomerulosa cells are oxygen sensitive: low PO2 inhibits aldosteronogenesis in vitro. In: Hypoxia: The Adaptations, Sutton JR, Coates G, and Remmers JE, editors. B.C. Decker Inc, Toronto, 1990, p281, Abstract 26. |
55. Raff H, Kohandarvish S, Jankowski B. Aldosterone secretion in vitro is oxygen sensitive. FASEB Journal 4:1604A, 1990. |
56. Raff H, Papanek PE, Skelton MM, Cowley AW Jr. ACTH and vasopressin responses to insulin hypoglycemia in intact and neurohypophysectomized conscious dogs. Program of the 72nd Annual Meeting of the Endocrine Society, Atlanta, USA, Abstract #43 |
57. Brickner RC, Jankowski B, Raff H. Potassium stimulated aldosteronogenesis is oxygen sensitive. Program of the 72nd Annual Meeting of the Endocrine Society, Atlanta, USA, Abstract #1102. |
58. Doepker SK, Jankowski B, Raff H. Vasopressin response to almitrine in normoxic and hypoxic conscious rats. FASEB Journal 5:A373, 19091 (Abstract 17) |
59. Raff H, Nelson DK, Findling JW, and Kay J. Acute and chronic suppression of ACTH and cortisol after epidural steroid administration in humans. Program of the 73rd Annual Meeting of the Endocrine Society, Washington, USA, Abstract #65. |
60. Brickner RC, Jankowski BM, and Raff H. Oxygen sensitive steroidogenesis: inhibition of conversion of corticosterone to aldosterone in cyanoketone treated adrenal zona glomerulosa cells. Program of the 73rd Annual Meeting of the Endocrine Society, Washington, USA, Abstract #143. |
61. Wood CE and Raff H. Arterial baroreceptors do not modulate the vasopressin response to hypoxia in late gestation fetal sheep. The Physiologist 34:241, 1991 (Abstract 27.12) |
62. Kay J, Raff H, Findling JW. Epidural triamcinalone causes prolonged and severe suppression of the pituitary adrenal axis. Anesthesiology 75:A694, 1991. |
63. Raff H and Jankowski B. Interaction of hypercapnic acidosis and hypoxia on aldosteronogenesis in vitro. FASEB J. 6:4852, 1992. |
64. Papanek PE, Cowley AW, Schmitt GW, and Raff H. Effect of hypotension and hyperosmolality on vasopressin and ACTH responses to hypoglycemia in conscious dogs. FASEB J. 6:3038, 1992 |
65. Doepker, S.K., B. Jankowski, and H. Raff. The sensitivity of aldosterone synthesis to carbon monoxide vs. low oxygen in vitro. 74th Annual Endocrine Society Meetings, San Antonio, TX, 1992, Abstract #82. |
66. Schwartz, J., P. Ash, and H. Raff. Glucocorticoid induced inhibition of the pituitary ACTH response to AVP: effect of elimination of CRF target cells. 74th Annual Endocrine Society Meetings, San Antonio, TX, 1992, Abstract #1312. |
67. Papanek, P.E., B. Jankowski, and H. Raff. Differential sensitivity of the aldosteronogenic pathway to hypoxia during maturation in rabbits. 75th Annual Endocrine Society Meetings, Las Vegas, NV, 1993, Abstract #1528 |
68. Raff, H and P.E. Papanek. Chronic physiological increases in cortisol inhibit vasopressin in conscious dogs. 75th Annual Endocrine Society Meetings, Las Vegas, NV, 1993, Abstract #788 |
69. Kay, J, H. Raff, and J.W. Findling. Epidural triamcinolone causes prolonged and severe suppression of the pituitary adrenal axis. Regional Anesthesia 18:55, 1993. |
70. Torres, A. and H. Raff. Renin aldosterone dissociation in critically ill children. 6th Pediatric Critical Care Colloquium, Philadelphia, PA, March, 1993. |
71. Buggy BP, Brummitt CF, Gilson IH, Bernstein BM, Raff H, and Findling JW. Longitudinal evaluation of adrenocortical function in patients with HIV 1 infection. IXth International Conference on AIDS, Berlin, Germany, 1993 |
72. Raff, H, P.E. Papanek, J F Liard, and A.W. Cowley. Intracarotid vasopressin infusion normalizes the ACTH response to hypotension in neurohypophysectomized, conscious dogs. Soc. Neurosci. Abstr. 19, 415, 1993 |
73. Raff H, Jankowski B, and Papanek PE. Hypoxia inhibits aldosterone production from rat adrenocortical zona glomerulosa cells in vitro. FASEB J. 8:A554, 1994 |
74. Papanek PE and Raff H. Chronic physiological increases in cortisol inhibit the vasopressin response to hypertonic saline in conscious dogs. FASEB J. 8:A824, 1994 |
75. Raff H, Shaker JL, Seifert PE, Werner PH, Hazelrigg SR, and Findling JW. Intraoperative measurement of ACTH during removal of ACTH-secreting bronchial carcinoid tumors. 76th Annual Endocrine Society Meeting, Anaheim, CA, 1994, Abstract #42. |
76. Raff H and Jankowski B. Oxygen dependence of side-chain cleavage and aldosterone synthase in mitochondria isolated from bovine zona glomerulosa cells. 76th Annual Endocrine Society Meeting, Anaheim, CA, 1994, Abstract #220. |
77. Brickner RC, Raff H, Shaker JL, Findling JW. Increased ACTH by immunoradiometric assay is an early indicator of primary adrenal insufficiency. 76th Annual Endocrine Society Meeting, Anaheim, CA, 1994, Abstract #1266. |
78. Lucero P, Jankowski B, Papanek PE, Raff H. Aldosterone production in vitro in zona glomerulosa cells from rats exposed to hypoxia in vivo. FASEB J. 9:A597, 1995. |
79. Raff H, Lucero P, Cowles VE, Papanek PE. Vasopressin response to corticotropin-releasing factor and hypertonicity before and after abdominal vagotomy in conscious dogs. FASEB J. 9:A263, 1995. |
80. Papanek PE, Sladek CD, and Raff H. The effect of corticosterone and RU486 on vasopressin responses to hyperosmolality in rat hypothalamo-neurohypophysial explants. FASEB J. 9:A264, 1995 |
81. Raff H, Kehoe ME, and Findling JW. DDAVP increases inferior petrosal sinus ACTH concentration in patients with pituitary and ectopic ACTH-dependent Cushing's syndrome. 77th Annual Endocrine Society Meeting, Washington, DC, 1995, OR39-6, p100. |
82. Findling JW, Raff H, Hansson JH, Lifton RP. Liddle's syndrome: a new kindred with a unique mutation in the -subunit of the renal epithelial sodium channel clinically identified by hypoaldosteronism. 77th Annual Endocrine Society Meeting, Washington, DC, 1995, OR10-2, p59. |
83. Raff H, Jankowski B, Engeland WC, Oaks MK, Papanek PE. Hypoxia in vivo inhibits the expression of aldosterone synthase (P450aldo) mRNA levels in the rat adrenal cortex. FASEB J 10:A812, 1996 |
84. Papanek PE, Jankowski BM, Baker JE, Goodfriend TL, Raff H. Exposure to hypoxia from birth increases free fatty acids and inhibits aldosterone production in rabbits. FASEB J 10:A812, 1996. |
85. Shaker JL, Kay J, Findling JW, Raff H. Epidural corticosteroid therapy is associated with a decrease in plasma osteocalcin. 10th International Congress of Endocrinology, San Francisco, CA 1996, P1-971, p377. |
86. Findling JW, Kehoe ME, Shaker JL, Brickner RC, Raff H. Correlation of the interpetrosal sinus gradient with the location of ACTH-secreting microadenomas. Program of the 4th International Pituitary Congress, pF9, 1996. |
87. Raff H, Jankowski BM, Engeland WC, Oaks MK. Aldosterone synthase (P450c11AS) activity and mRNA expression in adrenal cells from neonatal rats exposed to hypoxia from birth. 23rd International Aldosterone Conference, Minneapolis, MN, June 1997. |
88. Magill SB, Raff H, Shaker J, Brickner RC, Knechtges TE, Kehoe ME, Findling JW. Comparison of adrenal vein sampling and CT in the differentiation of primary aldosteronism. Endo '97: 79 Annual Meeting of the Endocrine Society, Minneapolis, MN, June 1997, Abstract P3-164. |
89. Raff H, Raff JL, Findling JW. Measurement of salivary cortisol in normal subjects and patients with Cushing's syndrome. Endo '97: 79 Annual Meeting of the Endocrine Society, Minneapolis, MN, June 1997, Abstract OR28-4. |
90. Raff JL, Raff H, Findling JW, Rudman I, Mattson D, Hammel G, Sasse E, Sheldahl L, Wilson C, Duthie E. Salivary cortisol levels are elevated in the evening in elderly women and men. Endo '98. 80th Annual Meeting of the Endocrine Society, Abstract P1-421 |
91. Raff H, Bruder E, Jankowski B, Goodfriend TL. The effect of 7 days of hypoxia in the neonatal and infant rat: plasma lipids, fatty acids, and lactate. Experimental Biology '99, Washington, D.C. Abstract 366.1, p130 |
92. Findling JW, Shaker HL, Brickner RC, Magill SB, Lalande BM, Raff H. Low-dose dexamethasone suppression testing cannot be used to exclude Cushing's Syndrome. 81st Annual Endocrine Society Meeting Abstracts, 1999, San Diego, Abstract OR21-3, p90. |
93. Raff H, Bruder ED, Nagler AK, Jankowski BM. The effect of hypoxia in vitro on cAMP and steroid production from rat adrenal cells. FASEB J 14:A639, 2000. Abstract 462.8. |
94. Raff H, Bruder ED, Jankowski BM. Effect of neonatal hypoxia from birth on corticosterone, leptin, and insulin at 7 days of age and after 14 days of normoxic recovery in the rat. Endocrine Society 82nd Annual Meeting, 2000, Toronto, CAN, Abstract 878, p215 |
95. Raff H, Findling JW, Singh RJ. Salivary cortisol/cortisone measurements: Cushing's syndrome and statins. Endocrine Society 83nd Annual Meeting, 2001, Denver, CO, Abstract OR21-1, p95 |
96. Bruder ED, Raff H, Goodfriend TL, and Ball DL. A metabolite of linoleic acid stimulates corticosterone production in the rat adrenal cortex. Abstract of 84th Annual Meeting of Endocrine Society, Abstract P1-505, 2002. |
97. Sujatanond P, Shaker JL, Lalande BM, Raff H, Findling JW. Hyperthyroidism increases morbidity in patients who undergo open-heart surgery: a retrospective analysis at the single institution. Abstract of 85th Annual Meeting of Endocrine Society, Abstract P1-508, 2003. |
98. Taylor RL, Grebe SK, Findling JW, Raff H, Singh RL. Diagnosis of Cushing's syndrome with a sensitive and specific LC-MS/MS method for late night salivary cortisol. Abstract of 85th Annual Meeting of Endocrine Society, Abstract P2-563, 2003. |
99. Bruder ED, Goodfriend TL, Ball DL, Raff H. Corticosterone responses to an oxidized metabolite of linoleic acid by rat adrenal cells in vitro: interaction with ACTH, and roles of cAMP and PKC. Abstract of 85th Annual Meeting of Endocrine Society, Abstract P3-176, 2003. |
100. Bruder ED, Lee PC, Raff H. Hepatic lipid profiling in the neonatal rat: effects of hypoxia and dexamethasone. Program of the NIH Conference - Lipids and Pathophysiology of Obesity. May 10-11, 2004, Abstract #4. |
101. Findling JW, Kehoe ME, Raff H. Prolactin as an index of pituitary venous effluent: identification of patients with Cushing's disease with negative pituitary ACTH gradients during inferior petrosal sinus sampling. Abstracts of 86th Annual Meeting of the Endocrine Society (Endo2004), Abstract P2-452, 2004. |
102. Bruder ED, Raff H, Ball DL, Goodfriend TL. An oxidized metabolite of linoleic acid modulates androgen production by isolated human adrenocortical cells. Abstracts of 86th Annual Meeting of the Endocrine Society (Endo2004), Abstract P3-295. |
103. Brock SA, Raff H, Findling JW. Cosyntropin-stimulated salivary cortisol as a surrogate for serum free cortisol in hospitalized patients. Abstracts of 87th Annual Meeting of the Endocrine Society (Endo2005). Abstract P3-434 |
104. Klinger JE, Bruder ED, Raff H. Steroidogenesis in neonatal vs. adult rats: effects of catecholamines and NPY. Abstracts of 87th Annual Meeting of the Endocrine Society (Endo2005). Abstract P2-303 |
105. Bruder ED, Jacobson L, Raff H. Effects of dexamethasone on leptin, ghrelin, and corticosterone and on pituitary POMC and CRHR1 mRNA expression in the normoxic and hypoxic neonatal rat. Abstracts of 87th Annual Meeting of the Endocrine Society (Endo2005). Abstract P3-4 |
106. Liu H, Cabaccan J, Raff H, Findling J, Ryzen E. Late-night salivary cortisol as a screening test for Cushing's syndrome in male obese diabetic veterans. Abstracts of 87th Annual Meeting of the Endocrine Society (Endo2005). Abstract P2-523 |
107. Bruder ED, Lee JJ, Widmaier EP, Raff H. Microarray and real-time PCR analysis of adrenal gland gene expression in the 7-day old rat: effects of hypoxia from birth. Abstracts of 88th Annual Meeting of the Endocrine Society (Endo2006). Abstract P1-500. |
108. Kidambi S, Raff H, Findling JW. The diagnosis of mild Cushing's syndrome in patients with normal urine free cortisol: utility of nocturnal salivary cortisol Abstracts of 88th Annual Meeting of the Endocrine Society (Endo2006). Abstract P3-871. |
109. Carroll T, Raff H, Findling JW. Nocturnal salivary cortisol for the diagnosis of Cushing's syndrome: a meta-analysis. Abstracts of 90th Annual Meeting of the Endocrine Society (Endo2008). Abstract OR40-3 |
110. Mepani JB, Findling JW, Salvatori R, Toth DW, Nora EH, Raff H. Discordant Late-Night Salivary Cortisol Results: A Retrospective Analysis. Abstracts of 91st Annual Meeting of the Endocrine Society (Endo2009). Abstract P1-623 |
111. Bangaru MLY, Woodliff J, Chen S, Raff H, Kansra S. A Novel Therapeutic Agent for Cushing's Disease: Curcumin (Diferyloylmethone) Inhibits Proliferation and ACTH Secretion in AtT20 Cells. Abstracts of 91st Annual Meeting of the Endocrine Society (Endo2009). Abstract P3-577 |
112. Cohen E, Bruder ED, Jankowski BM, Raff H. Pituitary-adrenal function after total body irradiation: effect of head shielding. J. Investigat. Med 58:671, 2010 |
113. Raff H, Trivedi H. Assessment of the Circadian Rhythm of the HPA Axis in End-Stage Renal Disease (ESRD) Using Salivary and Serum Cortisol. Endocrine Reviews 31:S1575, 2010 |
114. Bruder ED, Kamer KJ, Guenther MA, Raff H. Hypothalamic-Pituitary-Adrenocortical, Catecholamine, Glucose, and Endocrine Pancreas Responses to Acute Hypoxia in the Neonatal Rat: Effect of Spontaneous Hypothermia Versus Maintenance of Body Temperature. Am Acad Peds National Conference and Exhibition, 2010, San Francisco, CA, Abstract 8887 - Oral Presentation |
115. Guenther MA, ED Bruder, and Raff H. Interaction of acute hypoxia and body temperature on metabolic and endocrine responses in the neonatal rat: effect of preventing spontaneous hypothermia. Experimental Biology 2011, Abstract 1110.7 |
116. Sharma ST, Raff H, Nieman LK. Prolactin as a marker of successful catheterization during inferior petrosal sinus sampling (IPSS) in patients with ACTH-dependent Cushing syndrome. Endocr Rev 32: P3-536 |
117. Sharma ST, Raff H, Nieman LK. Prolactin as a marker of successful catheterization during inferior petrosal sinus sampling (IPSS) in patients with ACTH-dependent Cushing syndrome. Endocr Rev 32: P3-536, 2011 |
118. Guenther MA, Bruder ED, Chintamaneni K, Raff H. Insulin, C-peptide, glucose, and heart rate responses to acute intermittent hypoxia in the neonatal rat: body temperature and chemical sympathectomy. Experimental Biology 2012, Abstract 896.1
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119. Chintamaneni K, Bruder ED, Guenther MA, Raff H. Response of the HPA axis to intermittent hypoxia in the neonatal rat: ACTH, corticosterone, and the expression of adrenal mRNAs. Experimental Biology 2012, Abstract 896.5
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120. Miranda A, Raff H, Williams S. Salivary Amylase as a Biomarker for Functional Abdominal Pain in Children: Role of Sleep and Melatonin. J Pediatr Gastroenterol Nutr. Volume 55, Suppl 1, October 2012. |
121. Johnson K, Bruder ED, Engeland WC, Raff H. Acute hypoxia in neonatal rats: a novel ACTH- and cAMP-independent control of adrenal function. Experimental Biology 2013, Abstract 1207.4 |
122. Chintamaneni K., Bruder E, Guenther MA, Raff H. Intermittent hypoxia in the neonate leads to an augmented stress response in adult rats. Experimental Biology 2013, Abstract 938.5 |
123. Bruder ED, Nunez L, Hoffman MJ, Moreno C, Raff H. Control of aldosterone release in vitro in the renin knockout rat. Experimental Biology 2013, Abstract 909.3 |
124. Sharma ST, Raff H, Lonser RR, Oldfield EH, Nieman LK. Does prolactin measurements improve lateralization during IPSS in patients with Cushing’s disease? ENDO13 Abstract OR42-2 |
125. Venkatesan T, Samuel EA, Kumar N, Sengupta J, Ali M, Faddis M, Raff H, Hillard C. The Endocannabinoid System (ECS) and the Hypothalamic-Pituitary-Adrenal (HPA) Axis in Adults With Cyclic Vomiting Syndrome (CVS). Gastroenterology 144 (5), S-924, 2013 |
126. Agrawal ST, Rajca B, Leo J, Kumaravel V, Fahler J, Raff H, Guda NM. Progression of fellow's competence in ERCP training: the Proficient Study. Gastroenterology 81 (5), AB164-AG165, 2015. |
127. Nensey NK, Bodager J, Gehrand A, Raff H. Effect of a novel melanocortin type 2 receptor (MC2R) antagonist on the corticosterone response to ACTH in the neonatal rat. ENDO16 Abstract SUN 406 |
128. Gehrand A, Phillips J, Malott K, Raff H. Effect of a Novel Long-Acting Neutralizing Monoclonal ACTH Antibody (ALD1611) in the Neonatal Rat: Basal and the Corticosterone Responses to ACTH and Hypoxic Stress. ENDO18 Abstract SAT-510 |
129. Kanagala V, Esteban JP, Raff H, Venkatesan T. Cortisol awakening response is reduced in patients with cyclic vomiting syndrome. Gastroenterology, 2018-05-01, Volume 154, Issue 6, Pages S-553-S-554. |
130. Gehrand A, Phillips JM, Malott K, Raff H. Effect of a novel long-acting neutralizing monoclonal ACTH antibody (ALD1611) in the neonatal rat: basal and corticosterone responses to ACTH and hypoxic stress. J Patient Cent Res Rev. 5:318, 2018. 10.17294/2330-0698.1664. |
131. Kannankeril J, Carroll TB, Finding JW, Javorsky BR, Gunsolus I, Phillips J, Raff H. Comparison of a late-night salivary cortisol immunoassay and a cortisol and cortisone LCMS assay in patients with Cushing’s disease. Journal of the Endocrine Society, Volume 4, Issue Supplement_1, April-May 2020, MON-172, https://doi.org/10.1210/jendso/bvaa046.534 |
132. Welhouse KD, Gehrand A, Phillips J, Siddiqui H, Schulgit M, Raff H. A novel glucocorticoid receptor antagonist (CORT113176) reveals unique developmental and tissue-specific effects in a neonatal rat model of human prematurity. Journal of the Endocrine Society, Volume 4, Issue Supplement_1, April-May 2020, SUN–214, https://doi.org/10.1210/jendso/bvaa046.321 |
133. Nelson LD, Guzowski NS, Ekong M, Powell J, Kotsonis TA, Huber D, Raff H, McCrea MA, Johnson BD, Leddy JJ. Changes in and correlates of autonomic nervous system function after mild traumatic brain injury. Psychophysiology, 57(S1), S75, 2020 |
134. Nelson LD, Guzowski NS, Ekong M, Powell J, Kotsonis TA, Huber D, Raff H, McCrea MA, Johnson BD, Leddy JJ. Changes in and correlates of autonomic nervous system function after mild traumatic brain injury. Psychophysiology, 57(S1), S75, 2020 |
135. Musacchio S, Raff H, Leddy JJ, Johnson BD, McCrea MA, Meier TB, & Nelson LD. Altered HPA and ANS activity post-concussion: Characteristics and clinical correlations. Psychoneuroendocrinology, 119 (Suppl.), 2020 doi: 10.1016/j.psyneuen.2020.104958 |
136. Gehrand A, Phillips J, Welhouse KD, Schulgit M, Siddiqui H, Raff H. The effect of a novel glucocorticoid receptor antagonist (CORT113176) on glucocorticoid and insulin receptor sensitive hepatic gene (mRNA) expression in a neonatal rat model of human prematurity. Journal of the Endocrine Society, Volume 5, Issue Supplement_1, April-May 2021, Page A818, https://doi.org/10.1210/jendso/bvab048.1667 |
137. Pant T, Berens RJ, Henry A, Taylor SP, Raff H, Bosnjak Z. Association between S100β, NSE and BDNF levels and different exposure time of general anesthetics in pediatric patients undergoing non-cardiac surgeries. IARS Annual Meeting, Abstract #994, May 13-15, 2021. |
138. Hainsworth KR, Hillard CJ, Simpson PL, Raff H, Zhang L, Grayson M, Weisman SJ. Dysregulation of the endocannabinoid system in adolescents with chronic pain: The importance of sex and obesity. Poster accepted to the IASP Virtual World Congress on Pain, 9-11 and 16-18 June 2021. |
139. Raff H, Olsen C, Everson C. Sex differences in HPA axis dynamics in the rat: interaction of opioid abstinence and sleep restriction Abstract submitted on 7/30/2021 for APS Meeting - New Trends in Sex and Gender Medicine, October 19–22, 2021. |
140. Raff H, Phillips J, Weisman S, Hainsworth K. Interaction of sex, chronic pain and obesity on cortisol in adolescent humans. Abstract submitted on 7/30/2021 for APS Meeting - New Trends in Sex and Gender Medicine, October 19–22, 2021 |
141. Vogg N, Kurlbaum M, Raff H, Fassnacht M, Kroiss M. Method comparison and threshold evaluation for cortisol measured with CLIA and LC-MS/MS in dexamethasone suppression test. 20th Scientific Meeting of the European Network for the Study of Adrenal Tumors (ENSAT), topic NAPACA, taking place online from September 30th- October 2nd, 2021. |
142. Raff H, Gonzalez PA, Simcox J, Wade G, Von Bank H, Weisman SJ, Hainsworth KR. Lipid Signatures of Chronic Pain in Female Adolescents With and Without Obesity. Conference proceedings: Select abstracts presented at Advocate Aurora Scientific Day 2022. J Patient Cent Res Rev. 2022;9:298-314. doi: 10.17294/2330-0698.2014 |
143. Gehrand AL, Phillips J, Raff H. Early-Life Periodic Hypoxia With Pain Elicits Increases in Corticosterone and Insulin Resistance Index in a Neonatal Rat Model of Human Prematurity. Conference proceedings: Select abstracts presented at Advocate Aurora Scientific Day 2022. J Patient Cent Res Rev. 2022;9:298-314. doi: 10.17294/2330-0698.2014 |
Peer Reviewed Educational Products |
1. Online Learning: Vitamin D Regulation, Clinical Significance and Treatment. American Society for Clinical Laboratory Science (ASCLS) 2012
https://ascls.site-ym.com/store/view_product.asp?id=948663
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2. Salivary Cortisol Test for Cushing’s Syndrome - Patient Information – Cushing’s Support & Research Foundation 12-30-16; http://csrf.net/doctors-articles/salivary-cortisol-a-screening-technique/ |