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Adeleye James Afolayan MD

Adeleye James Afolayan MD profile photo picture

Associate Professor

Institution: Medical College of Wisconsin
Department: Pediatrics
Division: Neonatology

Member of the Cancer Center

Publications (16)

  • Decreased OLA1 (Obg-Like ATPase-1) Expression Drives Ubiquitin-Proteasome Pathways to Downregulate Mitochondrial SOD2 (Superoxide Dismutase) in Persistent Pulmonary Hypertension of the Newborn. (Schultz A, Olorundami OA, Teng RJ, Jarzembowski J, Shi ZZ, Kumar SN, Pritchard K Jr, Konduri GG, Afolayan AJ) Hypertension 2019 10;74(4):957-966 PMID: 31476900 PMCID: PMC6739165 SCOPUS ID: 2-s2.0-85072134040 09/04/2019       1 Citation
  • Altered hypoxia-inducible factor-1α (HIF-1α) signaling contributes to impaired angiogenesis in fetal lambs with persistent pulmonary hypertension of the newborn (PPHN). (Makker K, Afolayan AJ, Teng RJ, Konduri GG) Physiol Rep 2019 02;7(3):e13986 PMID: 30706701 PMCID: PMC6355993 SCOPUS ID: 2-s2.0-85060932463 02/02/2019    
  • Dynamic Phosphorylation of the C Terminus of Hsp70 Regulates the Mitochondrial Import of SOD2 and Redox Balance. (Zemanovic S, Ivanov MV, Ivanova LV, Bhatnagar A, Michalkiewicz T, Teng RJ, Kumar S, Rathore R, Pritchard KA Jr, Konduri GG, Afolayan AJ) Cell Rep 2018 11 27;25(9):2605-2616.e7 PMID: 30485823 PMCID: PMC6377235 SCOPUS ID: 2-s2.0-85056969024 11/30/2018       15 Citations
  • Attenuation of endoplasmic reticulum stress by caffeine ameliorates hyperoxia-induced lung injury. (Teng RJ, Jing X, Michalkiewicz T, Afolayan AJ, Wu TJ, Konduri GG) Am J Physiol Lung Cell Mol Physiol 2017 05 01;312(5):L586-L598 PMID: 28213471 PMCID: PMC5451596 SCOPUS ID: 2-s2.0-85018731493 02/19/2017       30 Citations
  • Domain Mapping of Heat Shock Protein 70 Reveals That Glutamic Acid 446 and Arginine 447 Are Critical for Regulating Superoxide Dismutase 2 Function. (Afolayan AJ, Alexander M, Holme RL, Michalkiewicz T, Rana U, Teng RJ, Zemanovic S, Sahoo D, Pritchard KA Jr, Konduri GG) J Biol Chem 2017 02 10;292(6):2369-2378 PMID: 28028182 PMCID: PMC5313107 SCOPUS ID: 2-s2.0-85012108909 12/29/2016       3 Citations
  • Decreased endothelial nitric oxide synthase expression and function contribute to impaired mitochondrial biogenesis and oxidative stress in fetal lambs with persistent pulmonary hypertension. (Afolayan AJ, Eis A, Alexander M, Michalkiewicz T, Teng RJ, Lakshminrusimha S, Konduri GG) Am J Physiol Lung Cell Mol Physiol 2016 Jan 01;310(1):L40-9 PMID: 26519208 PMCID: PMC4698434 11/01/2015       19 Citations
  • Nitrotyrosine impairs mitochondrial function in fetal lamb pulmonary artery endothelial cells. (Teng RJ, Wu TJ, Afolayan AJ, Konduri GG) Am J Physiol Cell Physiol 2016 Jan 01;310(1):C80-8 PMID: 26491046 PMCID: PMC4698449 SCOPUS ID: 2-s2.0-84952801937 10/23/2015       5 Citations
  • Stepping Out of the Cytosol: AIMp1/p43 Potentiates the Link Between Innate and Adaptive Immunity. (Liang D, Halpert MM, Konduri V, Decker WK) Int Rev Immunol 2015;34(5):367-81 PMID: 26325028 09/02/2015       11 Citations
  • Interaction of endothelial nitric oxide synthase with mitochondria regulates oxidative stress and function in fetal pulmonary artery endothelial cells. (Konduri GG, Afolayan AJ, Eis A, Pritchard KA Jr, Teng RJ) Am J Physiol Lung Cell Mol Physiol 2015 Nov 01;309(9):L1009-17 PMID: 26320159 PMCID: PMC4628983 SCOPUS ID: 2-s2.0-84946434013 09/01/2015       6 Citations
  • Altered prostanoid metabolism contributes to impaired angiogenesis in persistent pulmonary hypertension in a fetal lamb model. (Mahajan CN, Afolayan AJ, Eis A, Teng RJ, Konduri GG) Pediatr Res 2015 Mar;77(3):455-62 PMID: 25521916 PMCID: PMC4346417 12/19/2014       9 Citations
  • Nogo-B receptor modulates angiogenesis response of pulmonary artery endothelial cells through eNOS coupling. (Teng RJ, Rana U, Afolayan AJ, Zhao B, Miao QR, Konduri GG) Am J Respir Cell Mol Biol 2014 Aug;51(2):169-77 PMID: 24568601 PMCID: PMC4148038 02/27/2014       11 Citations
  • Inducible HSP70 regulates superoxide dismutase-2 and mitochondrial oxidative stress in the endothelial cells from developing lungs. (Afolayan AJ, Teng RJ, Eis A, Rana U, Broniowska KA, Corbett JA, Pritchard K, Konduri GG) Am J Physiol Lung Cell Mol Physiol 2014 Feb 15;306(4):L351-60 PMID: 24375796 PMCID: PMC3920226 SCOPUS ID: 2-s2.0-84894025712 01/01/2014       28 Citations
  • Antenatal betamethasone improves postnatal transition in late preterm lambs with persistent pulmonary hypertension of the newborn. (Konduri GG, Bakhutashvili I, Eis A, Afolayan A) Pediatr Res 2013 May;73(5):621-9 PMID: 23370411 PMCID: PMC3749924 02/02/2013       7 Citations
  • AMP kinase activation improves angiogenesis in pulmonary artery endothelial cells with in utero pulmonary hypertension. (Teng RJ, Du J, Afolayan AJ, Eis A, Shi Y, Konduri GG) Am J Physiol Lung Cell Mol Physiol 2013 Jan 01;304(1):L29-42 PMID: 23103561 PMCID: PMC3543642 10/30/2012       27 Citations
  • Decreases in manganese superoxide dismutase expression and activity contribute to oxidative stress in persistent pulmonary hypertension of the newborn. (Afolayan AJ, Eis A, Teng RJ, Bakhutashvili I, Kaul S, Davis JM, Konduri GG) Am J Physiol Lung Cell Mol Physiol 2012 Nov 15;303(10):L870-9 PMID: 22962015 PMCID: PMC3517675 09/11/2012       49 Citations
  • Anti-inflammatory and analgesic activities of the aqueous extract of Acacia karroo stem bark in experimental animals. (Adedapo AA, Sofidiya MO, Masika PJ, Afolayan AJ) Basic Clin Pharmacol Toxicol 2008 Nov;103(5):397-400 PMID: 18803636 09/23/2008       13 Citations
  • Last update: 06/02/2020
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