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Adeleye James Afolayan MD
Associate Professor
Institution:
Medical College of Wisconsin
Department:
Pediatrics
Division:
Neonatology
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Publications (24)
Decreased Liver Kinase B1 Expression and Impaired Angiogenesis in a Murine Model of Bronchopulmonary Dysplasia.
(Rana U, Joshi C, Whitney E, Afolayan A, Dowell J, Teng RJ, Konduri GG)
Am J Respir Cell Mol Biol
2024 Oct;71(4):481-494 PMID: 38869353 SCOPUS ID: 2-s2.0-85205525955 06/13/2024
1 Citation
Aberrant PGC-1α signaling in a lamb model of persistent pulmonary hypertension of the newborn.
(Mooers EA, Johnson HM, Michalkiewicz T, Rana U, Joshi C, Afolayan AJ, Teng RJ, Konduri GG)
Pediatr Res
2024 Dec;96(7):1636-1644 PMID: 38844539 SCOPUS ID: 2-s2.0-85195582134 06/07/2024
Cellular Senescence Contributes to the Progression of Hyperoxic Bronchopulmonary Dysplasia.
(Jing X, Jia S, Teng M, Day BW, Afolayan AJ, Jarzembowski JA, Lin CW, Hessner MJ, Pritchard KA Jr, Naylor S, Konduri GG, Teng RJ)
Am J Respir Cell Mol Biol
2024 Feb;70(2):94-109 PMID: 37874230 SCOPUS ID: 2-s2.0-85184825553 10/24/2023
11 Citations
OLA1 Phosphorylation Governs the Mitochondrial Bioenergetic Function of Pulmonary Vascular Cells.
(Sidlowski P, Czerwinski A, Liu Y, Liu P, Teng RJ, Kumar S, Wells C, Pritchard K Jr, Konduri GG, Afolayan AJ)
Am J Respir Cell Mol Biol
2023 Apr;68(4):395-405 PMID: 36481055 PMCID: PMC10112427 SCOPUS ID: 2-s2.0-85151575149 12/09/2022
4 Citations
Role of endoplasmic reticulum stress in impaired neonatal lung growth and bronchopulmonary dysplasia.
(Pritchard KA Jr, Jing X, Teng M, Wells C, Jia S, Afolayan AJ, Jarzembowski J, Day BW, Naylor S, Hessner MJ, Konduri GG, Teng RJ)
PLoS One
2022;17(8):e0269564 PMID: 36018859 PMCID: PMC9417039 SCOPUS ID: 2-s2.0-85137126858 08/27/2022
14 Citations
Decreased Cyclic Guanosine Monophosphate-Protein Kinase G Signaling Impairs Angiogenesis in a Lamb Model of Persistent Pulmonary Hypertension of the Newborn.
(Sharma M, Rana U, Joshi C, Michalkiewicz T, Afolayan A, Parchur A, Joshi A, Teng RJ, Konduri GG)
Am J Respir Cell Mol Biol
2021 Nov;65(5):555-567 PMID: 34185619 PMCID: PMC8641848 SCOPUS ID: 2-s2.0-85118512266 06/30/2021
11 Citations
Decreased OLA1 (Obg-Like ATPase-1) Expression Drives Ubiquitin-Proteasome Pathways to Downregulate Mitochondrial SOD2 (Superoxide Dismutase) in Persistent Pulmonary Hypertension of the Newborn.
(Schultz A, Olorundami OA, Teng RJ, Jarzembowski J, Shi ZZ, Kumar SN, Pritchard K Jr, Konduri GG, Afolayan AJ)
Hypertension
2019 Oct;74(4):957-966 PMID: 31476900 PMCID: PMC6739165 SCOPUS ID: 2-s2.0-85072134040 09/04/2019
22 Citations
Altered hypoxia-inducible factor-1α (HIF-1α) signaling contributes to impaired angiogenesis in fetal lambs with persistent pulmonary hypertension of the newborn (PPHN).
(Makker K, Afolayan AJ, Teng RJ, Konduri GG)
Physiol Rep
2019 Feb;7(3):e13986 PMID: 30706701 PMCID: PMC6355993 SCOPUS ID: 2-s2.0-85060932463 02/02/2019
15 Citations
Dynamic Phosphorylation of the C Terminus of Hsp70 Regulates the Mitochondrial Import of SOD2 and Redox Balance.
(Zemanovic S, Ivanov MV, Ivanova LV, Bhatnagar A, Michalkiewicz T, Teng RJ, Kumar S, Rathore R, Pritchard KA Jr, Konduri GG, Afolayan AJ)
Cell Rep
2018 Nov 27;25(9):2605-2616.e7 PMID: 30485823 PMCID: PMC6377235 SCOPUS ID: 2-s2.0-85056969024 11/30/2018
45 Citations
A pilot study exploring the impact of cardiac medications on ciliary beat frequency: possible implications for clinical management.
(Loomba RS, Bhushan A, Afolayan AJ)
J Basic Clin Physiol Pharmacol
2018 Sep 25;29(5):565-571 PMID: 29723155 SCOPUS ID: 2-s2.0-85047086626 05/04/2018
2 Citations
Redox Signaling and Persistent Pulmonary Hypertension of the Newborn.
(Sharma M, Afolayan AJ)
Adv Exp Med Biol
2017;967:277-287 PMID: 29047092 SCOPUS ID: 2-s2.0-85032026417 10/20/2017
2 Citations
Attenuation of endoplasmic reticulum stress by caffeine ameliorates hyperoxia-induced lung injury.
(Teng RJ, Jing X, Michalkiewicz T, Afolayan AJ, Wu TJ, Konduri GG)
Am J Physiol Lung Cell Mol Physiol
2017 May 01;312(5):L586-L598 PMID: 28213471 PMCID: PMC5451596 SCOPUS ID: 2-s2.0-85018731493 02/19/2017
72 Citations
Domain Mapping of Heat Shock Protein 70 Reveals That Glutamic Acid 446 and Arginine 447 Are Critical for Regulating Superoxide Dismutase 2 Function.
(Afolayan AJ, Alexander M, Holme RL, Michalkiewicz T, Rana U, Teng RJ, Zemanovic S, Sahoo D, Pritchard KA Jr, Konduri GG)
J Biol Chem
2017 Feb 10;292(6):2369-2378 PMID: 28028182 PMCID: PMC5313107 SCOPUS ID: 2-s2.0-85012108909 12/29/2016
6 Citations
Decreased endothelial nitric oxide synthase expression and function contribute to impaired mitochondrial biogenesis and oxidative stress in fetal lambs with persistent pulmonary hypertension.
(Afolayan AJ, Eis A, Alexander M, Michalkiewicz T, Teng RJ, Lakshminrusimha S, Konduri GG)
Am J Physiol Lung Cell Mol Physiol
2016 Jan 01;310(1):L40-9 PMID: 26519208 PMCID: PMC4698434 SCOPUS ID: 2-s2.0-84953297007 11/01/2015
56 Citations
Nitrotyrosine impairs mitochondrial function in fetal lamb pulmonary artery endothelial cells.
(Teng RJ, Wu TJ, Afolayan AJ, Konduri GG)
Am J Physiol Cell Physiol
2016 Jan 01;310(1):C80-8 PMID: 26491046 PMCID: PMC4698449 SCOPUS ID: 2-s2.0-84952801937 10/23/2015
9 Citations
Stepping Out of the Cytosol: AIMp1/p43 Potentiates the Link Between Innate and Adaptive Immunity.
(Liang D, Halpert MM, Konduri V, Decker WK)
Int Rev Immunol
2015;34(5):367-81 PMID: 26325028 SCOPUS ID: 2-s2.0-84941880156 09/02/2015
17 Citations
Interaction of endothelial nitric oxide synthase with mitochondria regulates oxidative stress and function in fetal pulmonary artery endothelial cells.
(Konduri GG, Afolayan AJ, Eis A, Pritchard KA Jr, Teng RJ)
Am J Physiol Lung Cell Mol Physiol
2015 Nov 01;309(9):L1009-17 PMID: 26320159 PMCID: PMC4628983 SCOPUS ID: 2-s2.0-84946434013 09/01/2015
17 Citations
Altered prostanoid metabolism contributes to impaired angiogenesis in persistent pulmonary hypertension in a fetal lamb model.
(Mahajan CN, Afolayan AJ, Eis A, Teng RJ, Konduri GG)
Pediatr Res
2015 Mar;77(3):455-62 PMID: 25521916 PMCID: PMC4346417 SCOPUS ID: 2-s2.0-84938515685 12/19/2014
19 Citations
Nogo-B receptor modulates angiogenesis response of pulmonary artery endothelial cells through eNOS coupling.
(Teng RJ, Rana U, Afolayan AJ, Zhao B, Miao QR, Konduri GG)
Am J Respir Cell Mol Biol
2014 Aug;51(2):169-77 PMID: 24568601 PMCID: PMC4148038 SCOPUS ID: 2-s2.0-84905453070 02/27/2014
20 Citations
Inducible HSP70 regulates superoxide dismutase-2 and mitochondrial oxidative stress in the endothelial cells from developing lungs.
(Afolayan AJ, Teng RJ, Eis A, Rana U, Broniowska KA, Corbett JA, Pritchard K, Konduri GG)
Am J Physiol Lung Cell Mol Physiol
2014 Feb 15;306(4):L351-60 PMID: 24375796 PMCID: PMC3920226 SCOPUS ID: 2-s2.0-84894025712 01/01/2014
43 Citations
Antenatal betamethasone improves postnatal transition in late preterm lambs with persistent pulmonary hypertension of the newborn.
(Konduri GG, Bakhutashvili I, Eis A, Afolayan A)
Pediatr Res
2013 May;73(5):621-9 PMID: 23370411 PMCID: PMC3749924 SCOPUS ID: 2-s2.0-84879102728 02/02/2013
17 Citations
AMP kinase activation improves angiogenesis in pulmonary artery endothelial cells with in utero pulmonary hypertension.
(Teng RJ, Du J, Afolayan AJ, Eis A, Shi Y, Konduri GG)
Am J Physiol Lung Cell Mol Physiol
2013 Jan 01;304(1):L29-42 PMID: 23103561 PMCID: PMC3543642 SCOPUS ID: 2-s2.0-84871870815 10/30/2012
49 Citations
Decreases in manganese superoxide dismutase expression and activity contribute to oxidative stress in persistent pulmonary hypertension of the newborn.
(Afolayan AJ, Eis A, Teng RJ, Bakhutashvili I, Kaul S, Davis JM, Konduri GG)
Am J Physiol Lung Cell Mol Physiol
2012 Nov 15;303(10):L870-9 PMID: 22962015 PMCID: PMC3517675 SCOPUS ID: 2-s2.0-84869148621 09/11/2012
63 Citations
Anti-inflammatory and analgesic activities of the aqueous extract of Acacia karroo stem bark in experimental animals.
(Adedapo AA, Sofidiya MO, Masika PJ, Afolayan AJ)
Basic Clin Pharmacol Toxicol
2008 Nov;103(5):397-400 PMID: 18803636 SCOPUS ID: 2-s2.0-53949084685 09/23/2008
23 Citations
Last update: 08/07/2024