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John J. Reho

John J. Reho profile photo picture

Research Scientist II

Institution: Medical College of Wisconsin
Department: Physiology
Program: Cardiovascular Research Center


MCW Program / Core Facilities

  • Comprehensive Rodent Metabolic Phenotyping Core
  • Publications (39)

  • Body Composition and Metabolic Changes in a Lyon Hypertensive Congenic Rat and Identification of Ercc6l2 as a Positional Candidate Gene. (Clark KC, Wagner VA, Holl KL, Reho JJ, Tutaj M, Smith JR, Dwinell MR, Grobe JL, Kwitek AE) Front Genet 2022;13:903971 PMID: 35812759 PMCID: PMC9263446 SCOPUS ID: 2-s2.0-85134024483 07/12/2022       1 Citation
  • Chronic intracerebroventricular infusion of angiotensin II causes dose- and sex-dependent effects on intake behaviors and energy homeostasis in C57BL/6J mice. (Oliveira V, Reho JJ, Balapattabi K, Ritter ML, Mathieu NM, Opichka MA, Lu KT, Grobe CC, Silva SD Jr, Wackman KK, Nakagawa P, Segar JL, Sigmund CD, Grobe JL) Am J Physiol Regul Integr Comp Physiol 2022 Oct 01;323(4):R410-R421 PMID: 35816717 07/12/2022    
  • Low Sodium Supply in Early Life Causes Growth Restriction and Programs Long-Term Changes in Energy Homeostasis. (Ziegler AA, Grobe CC, Reho JJ, Grobe JL, Segar JL) FASEB J 2022 May;36 Suppl 1 PMID: 35555376 SCOPUS ID: 2-s2.0-85130017162 05/14/2022    
  • Female-Specific Features of Metabolic Syndrome in an LH Congenic Rat. (Clark KC, Wagner VA, Holl KL, Reho JJ, Grobe JL, Kwitek AE) FASEB J 2022 May;36 Suppl 1 PMID: 35555071 SCOPUS ID: 2-s2.0-85130021782 05/14/2022    
  • Genetic Background in the Rat Impacts Metabolic Outcomes of Post-wean BPF Exposure. (Wagner VA, Clark KC, Holl KL, Reho JJ, Solberg Woods LC, Lehmler HJ, Grobe JL, Kwitek AE) FASEB J 2022 May;36 Suppl 1 PMID: 35551835 SCOPUS ID: 2-s2.0-85130633183 05/14/2022    
  • Rho-related BTB Domain-containing Protein 1 Reverses Established Arterial Stiffness in Angiotensin II-treated Mice. (Fang S, Wu J, Reho J, Lu KT, Brozoski D, Werthman A, Kumar G, Silva SD, Muskus P, Wackman K, Mathison A, Urrutia RA, Teng BQ, Lin CW, Quelle FW, Sigmund CD) FASEB J 2022 May;36 Suppl 1 PMID: 35557171 SCOPUS ID: 2-s2.0-85130011716 05/14/2022    
  • Deletion of Prorenin Receptor in the Rostral Ventrolateral Medulla Results in Biphasic and Sex-Dependent Pressor Responses in Deoxycorticosterone Acetate-salt Hypertension. (Nakagawa P, Brozoski D, Mathieu NM, Lu KT, Gomez J, Reho J, Fang S, Segar JL, Grobe JL, Sigmund CD) FASEB J 2022 May;36 Suppl 1 PMID: 35557064 SCOPUS ID: 2-s2.0-85130045126 05/14/2022    
  • Endothelial Cullin3 Mutation Impairs Nitric Oxide-Mediated Vasodilation and Promotes Salt-Induced Hypertension. (Wu J, Fang S, Lu KT, Kumar G, Reho JJ, Brozoski DT, Otanwa AJ, Hu C, Nair AR, Wackman KK, Agbor LN, Grobe JL, Sigmund CD) Function (Oxf) 2022;3(3):zqac017 PMID: 35493997 PMCID: PMC9045850 05/03/2022    
  • Melanocortin MC4R receptor is required for energy expenditure but not blood pressure effects of angiotensin II within the mouse brain. (Oliveira V, Riedl RA, Claflin KE, Mathieu NM, Ritter ML, Balapattabi K, Wackman KK, Reho JJ, Brozoski DT, Morgan DA, Cui H, Rahmouni K, Burnett CML, Nakagawa P, Sigmund CD, Morselli LL, Grobe JL) Physiol Genomics 2022 06 01;54(6):196-205 PMID: 35476598 PMCID: PMC9131927 SCOPUS ID: 2-s2.0-85131018208 04/28/2022    
  • RhoBTB1 reverses established arterial stiffness in angiotensin II-induced hypertension by promoting actin depolymerization. (Fang S, Wu J, Reho JJ, Lu KT, Brozoski DT, Kumar G, Werthman AM, Silva SD Jr, Muskus Veitia PC, Wackman KK, Mathison AJ, Teng BQ, Lin CW, Quelle FW, Sigmund CD) JCI Insight 2022 05 09;7(9) PMID: 35358093 PMCID: PMC9090250 SCOPUS ID: 2-s2.0-85129954550 04/01/2022    
  • Cardiometabolic effects of DOCA-salt in male C57BL/6J mice are variably dependent on sodium and nonsodium components of diet. (Patil CN, Ritter ML, Wackman KK, Oliveira V, Balapattabi K, Grobe CC, Brozoski DT, Reho JJ, Nakagawa P, Mouradian GC Jr, Kriegel AJ, Kwitek AE, Hodges MR, Segar JL, Sigmund CD, Grobe JL) Am J Physiol Regul Integr Comp Physiol 2022 06 01;322(6):R467-R485 PMID: 35348007 PMCID: PMC9054347 SCOPUS ID: 2-s2.0-85129779185 03/30/2022    
  • Methods for the Comprehensive in vivo Analysis of Energy Flux, Fluid Homeostasis, Blood Pressure, and Ventilatory Function in Rodents. (Reho JJ, Nakagawa P, Mouradian GC Jr, Grobe CC, Saravia FL, Burnett CML, Kwitek AE, Kirby JR, Segar JL, Hodges MR, Sigmund CD, Grobe JL) Front Physiol 2022;13:855054 PMID: 35283781 PMCID: PMC8914175 SCOPUS ID: 2-s2.0-85126220642 03/15/2022       3 Citations
  • Tissue-specific expression of myosin phosphatase subunits and isoforms in smooth muscle of mice and humans. (Oslin K, Reho JJ, Lu Y, Khanal S, Kenchegowda D, Prior SJ, Fisher SA) Am J Physiol Regul Integr Comp Physiol 2022 04 01;322(4):R281-R291 PMID: 35107022 PMCID: PMC8917933 SCOPUS ID: 2-s2.0-85125966515 02/03/2022       1 Citation
  • Short-term Housing in Metabolic Caging on Measures of Energy and Fluid Balance in Male C57BL/6J Mice ( Mus musculus). (Ziegler AA, Grobe CC, Reho JJ, Jensen ES, Thulin JD, Segar JL, Grobe JL) J Am Assoc Lab Anim Sci 2022 03 01;61(2):132-139 PMID: 34996529 PMCID: PMC8956215 SCOPUS ID: 2-s2.0-85126266838 01/09/2022       2 Citations
  • Pcpe2, a Novel Extracellular Matrix Protein, Regulates Adipocyte SR-BI-Mediated High-Density Lipoprotein Uptake. (Xu H, Thomas MJ, Kaul S, Kallinger R, Ouweneel AB, Maruko E, Oussaada SM, Jongejan A, Cense HA, Nieuwdorp M, Serlie MJ, Goldberg IJ, Civelek M, Parks BW, Lusis AJ, Knaack D, Schill RL, May SC, Reho JJ, Grobe JL, Gantner B, Sahoo D, Sorci-Thomas MG) Arterioscler Thromb Vasc Biol 2021 11;41(11):2708-2725 PMID: 34551590 PMCID: PMC8551036 SCOPUS ID: 2-s2.0-85118592107 09/24/2021       2 Citations
  • Endothelial BBSome is essential for vascular, metabolic, and retinal functions. (Jiang J, Reho JJ, Bhattarai S, Cherascu I, Hedberg-Buenz A, Meyer KJ, Tayyari F, Rauckhorst AJ, Guo DF, Morgan DA, Taylor EB, Anderson MG, Drack AV, Rahmouni K) Mol Metab 2021 11;53:101308 PMID: 34303879 PMCID: PMC8379702 SCOPUS ID: 2-s2.0-85113702369 07/26/2021       2 Citations
  • Vascular effects of disrupting endothelial mTORC1 signaling in obesity. (Reho JJ, Guo DF, Beyer AM, Wegman-Points L, Pierce GL, Rahmouni K) Am J Physiol Regul Integr Comp Physiol 2021 08 01;321(2):R228-R237 PMID: 34189960 PMCID: PMC8409911 SCOPUS ID: 2-s2.0-85112009191 07/01/2021       1 Citation
  • Gut Microbiota Represent a Major Thermogenic Biomass. (Riedl RA, Burnett CML, Pearson NA, Reho JJ, Mokadem M, Edwards RA, Kindel TL, Kirby JR, Grobe JL) Function (Oxf) 2021;2(3):zqab019 PMID: 33939772 PMCID: PMC8055641 05/04/2021    
  • Dissociable effects of dietary sodium in early life upon somatic growth, fluid homeostasis, and spatial memory in mice of both sexes. (Segar JL, Grobe CC, Balapattabi K, Ritter ML, Reho JJ, Grobe JL) Am J Physiol Regul Integr Comp Physiol 2021 04 01;320(4):R438-R451 PMID: 33439766 PMCID: PMC8238146 SCOPUS ID: 2-s2.0-85103803949 01/14/2021       4 Citations
  • mTORC1 (Mechanistic Target of Rapamycin Complex 1) Signaling in Endothelial and Smooth Muscle Cells Is Required for Vascular Function. (Reho JJ, Guo DF, Morgan DA, Rahmouni K) Hypertension 2021 02;77(2):594-604 PMID: 33356400 PMCID: PMC8678954 SCOPUS ID: 2-s2.0-85100070656 12/29/2020       5 Citations
  • Quantification of body fluid compartmentalization by combined time-domain nuclear magnetic resonance and bioimpedance spectroscopy. (Segar JL, Balapattabi K, Reho JJ, Grobe CC, Burnett CML, Grobe JL) Am J Physiol Regul Integr Comp Physiol 2021 01 01;320(1):R44-R54 PMID: 33085913 PMCID: PMC7847054 SCOPUS ID: 2-s2.0-85099721279 10/22/2020       3 Citations
  • Cardiovascular Regulation by the Neuronal BBSome. (Guo DF, Reho JJ, Morgan DA, Rahmouni K) Hypertension 2020 04;75(4):1082-1090 PMID: 32148123 PMCID: PMC7101031 SCOPUS ID: 2-s2.0-85081945837 03/10/2020       3 Citations
  • Smooth Muscle Cell-Specific Disruption of the BBSome Causes Vascular Dysfunction. (Reho JJ, Guo DF, Morgan DA, Rahmouni K) Hypertension 2019 10;74(4):817-825 PMID: 31422694 PMCID: PMC6739154 SCOPUS ID: 2-s2.0-85072133055 08/20/2019       8 Citations
  • Mechanistic Target of Rapamycin Complex 1 Signaling Modulates Vascular Endothelial Function Through Reactive Oxygen Species. (Reho JJ, Guo DF, Rahmouni K) J Am Heart Assoc 2019 05 07;8(9):e010662 PMID: 31020916 PMCID: PMC6512105 SCOPUS ID: 2-s2.0-85065308983 04/26/2019       20 Citations
  • Oxidative and inflammatory signals in obesity-associated vascular abnormalities. (Reho JJ, Rahmouni K) Clin Sci (Lond) 2017 Jul 15;131(14):1689-1700 PMID: 28667067 SCOPUS ID: 2-s2.0-85021853704 07/02/2017       48 Citations
  • Chronic vagal nerve stimulation prevents high-salt diet-induced endothelial dysfunction and aortic stiffening in stroke-prone spontaneously hypertensive rats. (Chapleau MW, Rotella DL, Reho JJ, Rahmouni K, Stauss HM) Am J Physiol Heart Circ Physiol 2016 07 01;311(1):H276-85 PMID: 27208157 PMCID: PMC4967207 SCOPUS ID: 2-s2.0-84983770735 05/22/2016       35 Citations
  • A splice variant of the myosin phosphatase regulatory subunit tunes arterial reactivity and suppresses response to salt loading. (Reho JJ, Kenchegowda D, Asico LD, Fisher SA) Am J Physiol Heart Circ Physiol 2016 06 01;310(11):H1715-24 PMID: 27084390 PMCID: PMC4935519 SCOPUS ID: 2-s2.0-84983786151 04/17/2016       8 Citations
  • The stress of maternal separation causes misprogramming in the postnatal maturation of rat resistance arteries. (Reho JJ, Fisher SA) Am J Physiol Heart Circ Physiol 2015 Nov;309(9):H1468-78 PMID: 26371173 PMCID: PMC4666972 SCOPUS ID: 2-s2.0-84946052610 09/16/2015       10 Citations
  • Unique gene program of rat small resistance mesenteric arteries as revealed by deep RNA sequencing. (Reho JJ, Shetty A, Dippold RP, Mahurkar A, Fisher SA) Physiol Rep 2015 Jul;3(7) PMID: 26156969 PMCID: PMC4552530 SCOPUS ID: 2-s2.0-85006165958 07/15/2015       8 Citations
  • Redox signaling and splicing dependent change in myosin phosphatase underlie early versus late changes in NO vasodilator reserve in a mouse LPS model of sepsis. (Reho JJ, Zheng X, Asico LD, Fisher SA) Am J Physiol Heart Circ Physiol 2015 May 01;308(9):H1039-50 PMID: 25724497 PMCID: PMC4551119 SCOPUS ID: 2-s2.0-84929688878 03/01/2015       19 Citations
  • TRA2β controls Mypt1 exon 24 splicing in the developmental maturation of mouse mesenteric artery smooth muscle. (Zheng X, Reho JJ, Wirth B, Fisher SA) Am J Physiol Cell Physiol 2015 Feb 15;308(4):C289-96 PMID: 25428883 PMCID: PMC4329427 SCOPUS ID: 2-s2.0-85047700459 11/28/2014       11 Citations
  • Neural programming of mesenteric and renal arteries. (Reho JJ, Zheng X, Benjamin JE, Fisher SA) Am J Physiol Heart Circ Physiol 2014 Aug 15;307(4):H563-73 PMID: 24929853 PMCID: PMC4137124 SCOPUS ID: 2-s2.0-84906084563 06/16/2014       19 Citations
  • Smooth muscle contractile diversity in the control of regional circulations. (Reho JJ, Zheng X, Fisher SA) Am J Physiol Heart Circ Physiol 2014 Jan 15;306(2):H163-72 PMID: 24186099 PMCID: PMC3920130 SCOPUS ID: 2-s2.0-84892569732 11/05/2013       33 Citations
  • In vivo gene delivery with L-tyrosine polyphosphate nanoparticles. (Ditto AJ, Reho JJ, Shah KN, Smolen JA, Holda JH, Ramirez RJ, Yun YH) Mol Pharm 2013 May 06;10(5):1836-44 PMID: 23510151 PMCID: PMC3755951 SCOPUS ID: 2-s2.0-84877261318 03/21/2013       8 Citations
  • Increased Myogenic Reactivity of Uterine Arteries from Pregnant Rats with Reduced Uterine Perfusion Pressure. (Reho JJ, Toot JD, Peck J, Novak J, Yun YH, Ramirez RJ) Pregnancy Hypertens 2012 Apr;2(2):106-114 PMID: 22679605 PMCID: PMC3366595 SCOPUS ID: 2-s2.0-84859164059 06/09/2012       13 Citations
  • Alterations in vasomotor systems and mechanics of resistance-sized mesenteric arteries from SHR and WKY male rats following in vivo testosterone manipulation. (Toot JD, Reho JJ, Ramirez RJ, Novak J, Ely DL) Biol Sex Differ 2012 Jan 03;3(1):1 PMID: 22214247 PMCID: PMC3264497 01/05/2012    
  • Testosterone increases myogenic reactivity of second-order mesenteric arteries in both defective and normal androgen receptor adult male rats. (Toot JD, Reho JJ, Novak J, Dunphy G, Ely DL, Ramirez RJ) Gend Med 2011 Feb;8(1):40-52 PMID: 21497771 SCOPUS ID: 2-s2.0-79954526466 04/19/2011       3 Citations
  • Hypertension induced by episodic reductions in uteroplacental blood flow in gravid rat. (Reho JJ, Peck J, Novak J, Ramirez RJ) Hypertens Pregnancy 2011;30(2):208-20 PMID: 20846047 SCOPUS ID: 2-s2.0-79953701666 09/18/2010       9 Citations
  • Colony social stress differentially alters blood pressure and resistance-sized mesenteric artery reactivity in SHR/y and WKY male rats. (Toot JD, Reho JJ, Novak J, Dunphy G, Ely DL, Ramirez RJ) Stress 2011 Jan;14(1):33-41 PMID: 20666653 SCOPUS ID: 2-s2.0-78650364443 07/30/2010       12 Citations
  • Last update: 09/30/2022