Medical College of Wisconsin
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Lezi E PhD

Lezi E PhD profile photo picture

Assistant Professor

Institution: Medical College of Wisconsin
Department: Cell Biology, Neurobiology and Anatomy
Program: Administration

View Curriculum Vitae

Publications (22)

  • Regulatory Roles of Antimicrobial Peptides in the Nervous System: Implications for Neuronal Aging (Bradey A. R. Stuart1, Ariel L. Franitza1 and Lezi E) Front. Cell. Neurosci. 03/07/2022    
  • An Antimicrobial Peptide and Its Neuronal Receptor Regulate Dendrite Degeneration in Aging and Infection. (E L, Zhou T, Koh S, Chuang M, Sharma R, Pujol N, Chisholm AD, Eroglu C, Matsunami H, Yan D) Neuron 2018 Jan 03;97(1):125-138.e5 PMID: 29301098 PMCID: PMC5757245 SCOPUS ID: 2-s2.0-85040594976 01/05/2018       55 Citations
  • Dorsal Root Ganglia Mitochondrial Biochemical Changes in Non-diabetic and Streptozotocin-Induced Diabetic Mice Fed with a Standard or High-Fat Diet. (Guilford BL, Ryals JM, Lezi E, Swerdlow RH, Wright DE) J Neurol Neurosci 2017;8(2) PMID: 28775932 PMCID: PMC5538136 08/05/2017    
  • Lactate's effect on human neuroblastoma cell bioenergetic fluxes. (E L, Swerdlow RH) Biochem Pharmacol 2016 Jan 01;99:88-100 PMID: 26592660 PMCID: PMC4706500 SCOPUS ID: 2-s2.0-84951794583 11/26/2015       10 Citations
  • Effect of one month duration ketogenic and non-ketogenic high fat diets on mouse brain bioenergetic infrastructure. (Selfridge JE, Wilkins HM, E L, Carl SM, Koppel S, Funk E, Fields T, Lu J, Tang EP, Slawson C, Wang W, Zhu H, Swerdlow RH) J Bioenerg Biomembr 2015 Apr;47(1-2):1-11 PMID: 25104046 PMCID: PMC4320989 SCOPUS ID: 2-s2.0-84922566816 08/12/2014       21 Citations
  • Oxaloacetate activates brain mitochondrial biogenesis, enhances the insulin pathway, reduces inflammation and stimulates neurogenesis. (Wilkins HM, Harris JL, Carl SM, E L, Lu J, Eva Selfridge J, Roy N, Hutfles L, Koppel S, Morris J, Burns JM, Michaelis ML, Michaelis EK, Brooks WM, Swerdlow RH) Hum Mol Genet 2014 Dec 15;23(24):6528-41 PMID: 25027327 PMCID: PMC4271074 SCOPUS ID: 2-s2.0-84938655903 07/17/2014       64 Citations
  • Effect of high-intensity exercise on aged mouse brain mitochondria, neurogenesis, and inflammation. (E L, Burns JM, Swerdlow RH) Neurobiol Aging 2014 Nov;35(11):2574-2583 PMID: 25002036 PMCID: PMC4171347 SCOPUS ID: 2-s2.0-84922763017 07/09/2014       68 Citations
  • Altering O-linked β-N-acetylglucosamine cycling disrupts mitochondrial function. (Tan EP, Villar MT, E L, Lu J, Selfridge JE, Artigues A, Swerdlow RH, Slawson C) J Biol Chem 2014 May 23;289(21):14719-30 PMID: 24713701 PMCID: PMC4031527 SCOPUS ID: 2-s2.0-84901407632 04/10/2014       74 Citations
  • Lactate administration reproduces specific brain and liver exercise-related changes. (E L, Lu J, Selfridge JE, Burns JM, Swerdlow RH) J Neurochem 2013 Oct;127(1):91-100 PMID: 23927032 PMCID: PMC4276250 SCOPUS ID: 2-s2.0-84884896415 08/10/2013       72 Citations
  • Bioenergetic flux, mitochondrial mass and mitochondrial morphology dynamics in AD and MCI cybrid cell lines. (Silva DF, Selfridge JE, Lu J, E L, Roy N, Hutfles L, Burns JM, Michaelis EK, Yan S, Cardoso SM, Swerdlow RH) Hum Mol Genet 2013 Oct 01;22(19):3931-46 PMID: 23740939 PMCID: PMC3888119 SCOPUS ID: 2-s2.0-84888799219 06/07/2013       105 Citations
  • Glycolysis-respiration relationships in a neuroblastoma cell line. (Swerdlow RH, E L, Aires D, Lu J) Biochim Biophys Acta 2013 Apr;1830(4):2891-8 PMID: 23313167 PMCID: PMC3594384 SCOPUS ID: 2-s2.0-84873744600 01/15/2013       36 Citations
  • Effect of cholinergic signaling on neuronal cell bioenergetics. (Lu J, E L, Roy N, Hutfles L, Selfridge E, Funk E, Burns JM, Swerdlow RH) J Alzheimers Dis 2013;33(4):1135-46 PMID: 23099815 PMCID: PMC3553319 SCOPUS ID: 2-s2.0-84873641621 10/27/2012       7 Citations
  • Mitochondrial abnormalities in Alzheimer's disease: possible targets for therapeutic intervention. (Silva DF, Selfridge JE, Lu J, E L, Cardoso SM, Swerdlow RH) Adv Pharmacol 2012;64:83-126 PMID: 22840745 PMCID: PMC3625400 SCOPUS ID: 2-s2.0-84864385007 07/31/2012       65 Citations
  • Effect of exercise on mouse liver and brain bioenergetic infrastructures. (E L, Lu J, Burns JM, Swerdlow RH) Exp Physiol 2013 Jan;98(1):207-19 PMID: 22613742 PMCID: PMC3540163 SCOPUS ID: 2-s2.0-84872173552 05/23/2012       32 Citations
  • Mitochondria in neurodegeneration. (Lezi E, Swerdlow RH) Adv Exp Med Biol 2012;942:269-86 PMID: 22399427 PMCID: PMC3618469 SCOPUS ID: 2-s2.0-84859910283 03/09/2012       151 Citations
  • Role of mitochondrial homeostasis and dynamics in Alzheimer's disease. (Selfridge JE, E L, Lu J, Swerdlow RH) Neurobiol Dis 2013 Mar;51:3-12 PMID: 22266017 PMCID: PMC3337963 SCOPUS ID: 2-s2.0-84871417031 01/24/2012       132 Citations
  • Potentiation of dietary restriction-induced lifespan extension by polyphenols. (Aires DJ, Rockwell G, Wang T, Frontera J, Wick J, Wang W, Tonkovic-Capin M, Lu J, E L, Zhu H, Swerdlow RH) Biochim Biophys Acta 2012 Apr;1822(4):522-6 PMID: 22265987 PMCID: PMC3643308 SCOPUS ID: 2-s2.0-84863275557 01/24/2012       18 Citations
  • Reduced mitochondria cytochrome oxidase activity in adult children of mothers with Alzheimer's disease. (Mosconi L, de Leon M, Murray J, E L, Lu J, Javier E, McHugh P, Swerdlow RH) J Alzheimers Dis 2011;27(3):483-90 PMID: 21841246 PMCID: PMC3291954 SCOPUS ID: 2-s2.0-80055088009 08/16/2011       77 Citations
  • Alternate day fasting impacts the brain insulin-signaling pathway of young adult male C57BL/6 mice. (Lu J, E L, Wang W, Frontera J, Zhu H, Wang WT, Lee P, Choi IY, Brooks WM, Burns JM, Aires D, Swerdlow RH) J Neurochem 2011 Apr;117(1):154-63 PMID: 21244426 PMCID: PMC3055925 SCOPUS ID: 2-s2.0-79952570641 01/20/2011       13 Citations
  • Polymorphic variation in cytochrome oxidase subunit genes. (Lu J, Wang K, Rodova M, Esteves R, Berry D, E L, Crafter A, Barrett M, Cardoso SM, Onyango I, Parker WD, Fontes J, Burns JM, Swerdlow RH) J Alzheimers Dis 2010;21(1):141-54 PMID: 20413852 PMCID: PMC2910218 SCOPUS ID: 2-s2.0-77954963850 04/24/2010       25 Citations
  • Mitochondrial respiration and respiration-associated proteins in cell lines created through Parkinson's subject mitochondrial transfer. (Esteves AR, Lu J, Rodova M, Onyango I, Lezi E, Dubinsky R, Lyons KE, Pahwa R, Burns JM, Cardoso SM, Swerdlow RH) J Neurochem 2010 May;113(3):674-82 PMID: 20132468 SCOPUS ID: 2-s2.0-77950661030 02/06/2010       69 Citations
  • Regulation of neuron mitochondrial biogenesis and relevance to brain health. (Onyango IG, Lu J, Rodova M, Lezi E, Crafter AB, Swerdlow RH) Biochim Biophys Acta 2010 Jan;1802(1):228-34 PMID: 19682571 SCOPUS ID: 2-s2.0-71849092123 08/18/2009       156 Citations
    • Last update: 03/10/2022