Medical College of Wisconsin
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Mitchell R. Dyer MD

Assistant Professor

Institution: Medical College of Wisconsin
Department: Surgery
Division: Vascular Surgery

Publications (22)

  • Alterations in visible light exposure modulate platelet function and regulate thrombus formation. (Andraska EA, Denorme F, Kaltenmeier C, Arivudainabi A, Mihalko EP, Dyer M, Annarapu GK, Zarisfi M, Loughran P, Ozel M, Williamson K, Mota Alvidrez RI, Thomas K, Shiva S, Shea SM, Steinman RA, Campbell RA, Rosengart MR, Neal MD) J Thromb Haemost 2025 Jan;23(1):123-138 PMID: 39299611 PMCID: PMC12066021 SCOPUS ID: 2-s2.0-85214348559 09/20/2024    
  • Protein is expressed in all major organs after intravenous infusion of mRNA-lipid nanoparticles in swine. (Ferraresso F, Badior K, Seadler M, Zhang Y, Wietrzny A, Cau MF, Haugen A, Rodriguez GG, Dyer MR, Cullis PR, Jan E, Kastrup CJ) Mol Ther Methods Clin Dev 2024 Sep 12;32(3):101314 PMID: 39253356 PMCID: PMC11382111 SCOPUS ID: 2-s2.0-85207769475 09/10/2024       2 Citations
  • Suppressing upregulation of fibrinogen after polytrauma mitigates thrombosis in mice. (Seadler MS, Ferraresso F, Bansal M, Haugen A, Hayssen WG, Flick MJ, de Moya M, Dyer MR, Kastrup CJ) J Trauma Acute Care Surg 2024 Sep 06 PMID: 39238094 PMCID: PMC11882931 SCOPUS ID: 2-s2.0-85203525705 09/06/2024       1 Citation
  • Reporting and analysis of sex in vascular surgery research. (Rubin MJ, Wakinekona NA, Reilly MA, Canales B, Sparapani R, Dyer M, Kibbe MR, Mansukhani NA) J Vasc Surg 2024 Dec;80(6):1871-1882 PMID: 38901638 PMCID: PMC11585452 SCOPUS ID: 2-s2.0-85199130838 06/21/2024    
  • siRNA-mediated reduction of a circulating protein in swine using lipid nanoparticles. (Cau MF, Ferraresso F, Seadler M, Badior K, Zhang Y, Ketelboeter LM, Rodriguez GG, Chen T, Ferraresso M, Wietrzny A, Robertson M, Haugen A, Cullis PR, de Moya M, Dyer M, Kastrup CJ) Mol Ther Methods Clin Dev 2024 Jun 13;32(2):101258 PMID: 38779336 PMCID: PMC11109470 SCOPUS ID: 2-s2.0-85192785732 05/23/2024    
  • Neutrophil extracellular traps regulate ischemic stroke brain injury. (Denorme F, Portier I, Rustad JL, Cody MJ, de Araujo CV, Hoki C, Alexander MD, Grandhi R, Dyer MR, Neal MD, Majersik JJ, Yost CC, Campbell RA) J Clin Invest 2022 May 16;132(10) PMID: 35358095 PMCID: PMC9106355 SCOPUS ID: 2-s2.0-85129709773 04/01/2022       208 Citations
  • Reduced cleavage of von willebrand factor by ADAMTS13 is associated with microangiopathic acute kidney injury following trauma. (Plautz WE, Haldeman SH, Dyer MR, Sperry JL, Guyette FX, Loughran PA, Alvikas J, Hassoune A, Hoteit L, Alsaadi N, Zuckerbraun BS, Rollins-Raval MA, Raval JS, Mota RI, Neal MD, A TACTIC Publication) Blood Coagul Fibrinolysis 2022 Jan 01;33(1):14-24 PMID: 34889809 PMCID: PMC8728687 SCOPUS ID: 2-s2.0-85123453807 12/11/2021       12 Citations
  • Cause-Specific Mortality as a Sequalae of Perioperative Stroke Following Cardiac and Vascular Surgery. (Reinert NJ, Patel BM, AlShaer QN, Wu L, Wisniewski S, Hager ES, Dyer MR, Thirumala PD) Neurologist 2021 Nov 30;27(1):21-26 PMID: 34855676 PMCID: PMC8727499 SCOPUS ID: 2-s2.0-85120936361 12/03/2021       1 Citation
  • Traumatic injury results in prolonged circulation of ultralarge von Willebrand factor and a reduction in ADAMTS13 activity. (Dyer MR, Plautz WE, Ragni MV, Alexander W, Haldeman S, Sperry JL, Guyette FX, Zuckerbraun BS, Rollins-Raval MA, Raval JS, Neal MD, A TACTIC Publication) Transfusion 2020 Jun;60(6):1308-1318 PMID: 32441353 SCOPUS ID: 2-s2.0-85085060912 05/23/2020       26 Citations
  • Correlation of Thromboelastography with Apparent Rivaroxaban Concentration: Has Point-of-Care Testing Improved? (Myers SP, Dyer MR, Hassoune A, Brown JB, Sperry JL, Meyer MP, Rosengart MR, Neal MD) Anesthesiology 2020 Feb;132(2):280-290 PMID: 31939843 SCOPUS ID: 2-s2.0-85077864515 01/16/2020       16 Citations
  • Endotoxin Engages Mitochondrial Quality Control via an iNOS-Reactive Oxygen Species Signaling Pathway in Hepatocytes. (Cyr A, Chambers L, Waltz PK, Whelan SP, Kohut L, Carchman E, Dyer M, Luciano J, Kautza B, Gomez HD, Otterbein LE, Rosengart MR, Shiva S, Zuckerbraun BS) Oxid Med Cell Longev 2019;2019:4745067 PMID: 31772705 PMCID: PMC6854992 SCOPUS ID: 2-s2.0-85074757798 11/28/2019       14 Citations
  • Platelet-derived extracellular vesicles released after trauma promote hemostasis and contribute to DVT in mice. (Dyer MR, Alexander W, Hassoune A, Chen Q, Brzoska T, Alvikas J, Liu Y, Haldeman S, Plautz W, Loughran P, Li H, Boone B, Sadovsky Y, Sundd P, Zuckerbraun BS, Neal MD) J Thromb Haemost 2019 Oct;17(10):1733-1745 PMID: 31294514 PMCID: PMC6773503 SCOPUS ID: 2-s2.0-85072746695 07/12/2019       64 Citations
  • ADAMTS13: origins, applications, and prospects. (Plautz WE, Raval JS, Dyer MR, Rollins-Raval MA, Zuckerbraun BS, Neal MD) Transfusion 2018 Oct;58(10):2453-2462 PMID: 30208220 SCOPUS ID: 2-s2.0-85053416110 09/13/2018       34 Citations
  • Intravenous administration of synthetic platelets (SynthoPlate) in a mouse liver injury model of uncontrolled hemorrhage improves hemostasis. (Dyer MR, Hickman D, Luc N, Haldeman S, Loughran P, Pawlowski C, Sen Gupta A, Neal MD) J Trauma Acute Care Surg 2018 Jun;84(6):917-923 PMID: 29538234 PMCID: PMC5970031 SCOPUS ID: 2-s2.0-85047982909 03/15/2018       39 Citations
  • Intravenous synthetic platelet (SynthoPlate) nanoconstructs reduce bleeding and improve 'golden hour' survival in a porcine model of traumatic arterial hemorrhage. (Hickman DA, Pawlowski CL, Shevitz A, Luc NF, Kim A, Girish A, Marks J, Ganjoo S, Huang S, Niedoba E, Sekhon UDS, Sun M, Dyer M, Neal MD, Kashyap VS, Sen Gupta A) Sci Rep 2018 Feb 15;8(1):3118 PMID: 29449604 PMCID: PMC5814434 SCOPUS ID: 2-s2.0-85042184588 02/17/2018       70 Citations
  • Deep vein thrombosis in mice is regulated by platelet HMGB1 through release of neutrophil-extracellular traps and DNA. (Dyer MR, Chen Q, Haldeman S, Yazdani H, Hoffman R, Loughran P, Tsung A, Zuckerbraun BS, Simmons RL, Neal MD) Sci Rep 2018 Feb 01;8(1):2068 PMID: 29391442 PMCID: PMC5794752 SCOPUS ID: 2-s2.0-85041584450 02/03/2018       150 Citations
  • Uncontrolled Hemorrhagic Shock Modeled via Liver Laceration in Mice with Real Time Hemodynamic Monitoring. (Dyer M, Haldeman S, Gutierrez A, Kohut L, Sen Gupta A, Neal MD) J Vis Exp 2017 May 21(123) PMID: 28570538 PMCID: PMC5608008 SCOPUS ID: 2-s2.0-85025131435 06/02/2017       14 Citations
  • In vitro characterization of SynthoPlate™ (synthetic platelet) technology and its in vivo evaluation in severely thrombocytopenic mice. (Shukla M, Sekhon UD, Betapudi V, Li W, Hickman DA, Pawlowski CL, Dyer MR, Neal MD, McCrae KR, Sen Gupta A) J Thromb Haemost 2017 Feb;15(2):375-387 PMID: 27925685 PMCID: PMC5305617 SCOPUS ID: 2-s2.0-85012157813 12/08/2016       56 Citations
  • Aged Human Stored Red Blood Cell Supernatant Inhibits Macrophage Phagocytosis in an HMGB1 Dependent Manner After Trauma in a Murine Model. (Zettel KR, Dyer M, Raval JS, Wu X, Klune JR, Gutierrez A, Triulzi DJ, Billiar TR, Neal MD) Shock 2017 Feb;47(2):217-224 PMID: 27488090 PMCID: PMC5235959 SCOPUS ID: 2-s2.0-84980340113 08/05/2016       11 Citations
  • Simultaneous extracorporeal membrane oxygenation and therapeutic plasma exchange procedures are tolerable in both pediatric and adult patients. (Dyer M, Neal MD, Rollins-Raval MA, Raval JS) Transfusion 2014 Apr;54(4):1158-65 PMID: 24117674 SCOPUS ID: 2-s2.0-84898913951 10/15/2013       33 Citations
  • A critical role for TLR4 induction of autophagy in the regulation of enterocyte migration and the pathogenesis of necrotizing enterocolitis. (Neal MD, Sodhi CP, Dyer M, Craig BT, Good M, Jia H, Yazji I, Afrazi A, Richardson WM, Beer-Stolz D, Ma C, Prindle T, Grant Z, Branca MF, Ozolek J, Hackam DJ) J Immunol 2013 Apr 01;190(7):3541-51 PMID: 23455503 PMCID: PMC3608826 SCOPUS ID: 2-s2.0-84875469082 03/05/2013       124 Citations
  • Toll-like receptor 4 is expressed on intestinal stem cells and regulates their proliferation and apoptosis via the p53 up-regulated modulator of apoptosis. (Neal MD, Sodhi CP, Jia H, Dyer M, Egan CE, Yazji I, Good M, Afrazi A, Marino R, Slagle D, Ma C, Branca MF, Prindle T Jr, Grant Z, Ozolek J, Hackam DJ) J Biol Chem 2012 Oct 26;287(44):37296-308 PMID: 22955282 PMCID: PMC3481327 SCOPUS ID: 2-s2.0-84868261605 09/08/2012       182 Citations
    • Last update: 02/24/2025