Medical College of Wisconsin
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Robert D. Nerenz PhD

Associate Professor

Institution: Medical College of Wisconsin
Department: Pathology
Division: Administration


Publications (61)

  • Clinical decision support improves autoimmune/paraneoplastic antibody panel utilization. (Nerenz RD, Hooshmand SI, Jackowiak E, Shirilla D, Yang Y, Yang K, Obeidat AZ) Am J Clin Pathol 2024 Sep 10 PMID: 39255415 09/10/2024    
  • Clinical Impact of New Reference Intervals for the Roche Prolactin II Immunoassay. (Earll E, Javorsky BR, Sarvaideo J, Straseski JA, Nerenz RD) J Endocr Soc 2024 Apr 06;8(6):bvae069 PMID: 38698869 PMCID: PMC11065352 SCOPUS ID: 2-s2.0-85192495436 05/03/2024       1 Citation
  • Commentary on Severe Hypokalemia Associated with Paralysis after a Large Carbohydrate Intake following Exercise. (Nerenz RD) Clin Chem 2024 Apr 03;70(4):588 PMID: 38565212 SCOPUS ID: 2-s2.0-85189525423 04/03/2024    
  • Commentary on Low Cortisol in a Cushingoid Patient. (Nerenz RD) Clin Chem 2023 Jun 01;69(6):562-563 PMID: 37258488 SCOPUS ID: 2-s2.0-85160761101 06/01/2023    
  • Cannabis positivity rates in 17 emergency departments across the United States with varying degrees of marijuana legalization. (Tolan NV, Krasowski MD, Mathias PC, Wiencek JR, Babic N, Chai PR, Chambliss AB, Choucair I, Demetriou CA, Erickson TB, Feldhammer M, French D, Hayes BD, Kang P, El-Khoury JM, Knezevic CE, Monte A, Nerenz RD, Okorodudu AO, Roper SM, Saitman A, Thiriveedhi V, Uljon SN, Vest A, Woodworth A, Yu M, Melanson SEF) Clin Toxicol (Phila) 2023 Apr;61(4):248-259 PMID: 37129223 PMCID: PMC10793079 SCOPUS ID: 2-s2.0-85157976345 05/02/2023       5 Citations
  • Persistent Hypercalcemia: Choose Your Testing Strategy Carefully. (Sharag Eldin R, Shaker J, Stachowiak S, Nerenz RD) Clin Chem 2023 Apr 03;69(4):330-335 PMID: 37010999 SCOPUS ID: 2-s2.0-85151804365 04/04/2023    
  • Potential Impact of Pharmacogenomic Single Nucleotide Variants in a Rural Caucasian Population. (Williams GR, Tsongalis GJ, Lewis LD, Barney RE, Cook LJ, Aaron Geno K, Nerenz RD) J Appl Lab Med 2023 Mar 06;8(2):251-263 PMID: 36611001 PMCID: PMC10539040 SCOPUS ID: 2-s2.0-85150000640 01/08/2023    
  • Review of SARS-CoV-2 Antigen and Antibody Testing in Diagnosis and Community Surveillance. (Nerenz RD, Hubbard JA, Cervinski MA) Clin Lab Med 2022 Dec;42(4):687-704 PMID: 36368790 PMCID: PMC9651919 SCOPUS ID: 2-s2.0-85141492762 11/12/2022    
  • AACC Guidance Document on the Use of Point-of-Care Testing in Fertility and Reproduction. (Nichols JH, Ali M, Anetor JI, Chen LS, Chen Y, Collins S, Das S, Devaraj S, Fu L, Karon BS, Kary H, Nerenz RD, Rai AJ, Shajani-Yi Z, Thakur V, Wang S, Yu HYE, Zamora LE) J Appl Lab Med 2022 Sep 01;7(5):1202-1236 PMID: 36047824 SCOPUS ID: 2-s2.0-85137138395 09/02/2022       2 Citations
  • An Opioid Hiding in Plain Sight: Loperamide-Induced False-Positive Fentanyl and Buprenorphine Immunoassay Results. (Geno KA, Badea A, Lynch KL, Jannetto P, Hubbard JA, Nerenz RD, Cervinski MA) J Appl Lab Med 2022 Oct 29;7(6):1318-1328 PMID: 36036092 SCOPUS ID: 2-s2.0-85141005657 08/30/2022       3 Citations
  • Reevaluating the Icterus Index Cutoff of a Jaffé Creatinine Method. (Alvarez YF, Kelliher MT, Hubbard JA, Nerenz RD, Cervinski MA) J Appl Lab Med 2022 Sep 01;7(5):1151-1157 PMID: 35899580 SCOPUS ID: 2-s2.0-85137136078 07/29/2022       2 Citations
  • Commentary on Questionable High Free T4 Concentrations: When Confirming against an Alternative Method Is Not Enough. (Nerenz RD) Clin Chem 2022 Sep 01;68(9):1133 PMID: 35869936 SCOPUS ID: 2-s2.0-85137135888 07/24/2022    
  • In Reply to Toward a Clearer Understanding of Accuracy and Proper Application of the IBP4/SHBG Ratio for Predicting Preterm Delivery. (Nerenz RD, Woodworth A, Farnsworth C, Schuler EE) J Appl Lab Med 2022 Jun 30;7(4):1006-1008 PMID: 35606316 SCOPUS ID: 2-s2.0-85133980979 05/24/2022    
  • Wastewater-Based SARS-CoV-2 Surveillance in Northern New England. (Toledo DM, Robbins AA, Gallagher TL, Hershberger KC, Barney RE, Salmela SM, Pilcher D, Cervinski MA, Nerenz RD, Szczepiorkowski ZM, Tsongalis GJ, Lefferts JA, Martin IW, Hubbard JA) Microbiol Spectr 2022 Apr 27;10(2):e0220721 PMID: 35412387 PMCID: PMC9045146 SCOPUS ID: 2-s2.0-85129249425 04/13/2022       14 Citations
  • Evaluating thyroid function in pregnant women. (Geno KA, Nerenz RD) Crit Rev Clin Lab Sci 2022 Nov;59(7):460-479 PMID: 35293284 SCOPUS ID: 2-s2.0-85126651099 03/17/2022       14 Citations
  • Comparison of Symptoms and Antibody Response Following Administration of Moderna or Pfizer SARS-CoV-2 Vaccines. (Kelliher MT, Levy JJ, Nerenz RD, Poore B, Johnston AA, Rogers AR, Stella MEO, Snow SE, Cervinski MA, Hubbard JA) Arch Pathol Lab Med 2022 Jun 01;146(6):677-685 PMID: 35188563 SCOPUS ID: 2-s2.0-85131108539 02/22/2022       9 Citations
  • Longitudinal Systemic and Mucosal Immune Responses to SARS-CoV-2 Infection. (Wright PF, Prevost-Reilly AC, Natarajan H, Brickley EB, Connor RI, Wieland-Alter WF, Miele AS, Weiner JA, Nerenz RD, Ackerman ME) J Infect Dis 2022 Sep 28;226(7):1204-1214 PMID: 35188974 PMCID: PMC8903457 SCOPUS ID: 2-s2.0-85137444332 02/22/2022       31 Citations
  • Retrospective Evaluation of the Antibody Prevalence in Epilepsy and Encephalopathy (APE2) Score. (Poore B, Hamilton R, Kelliher MT, Mahmood S, Mindiola-Romero AE, Richards R, Motanagh S, Cervinski MA, Nerenz RD) J Appl Lab Med 2022 Jan 05;7(1):36-45 PMID: 34996088 SCOPUS ID: 2-s2.0-85123269272 01/08/2022    
  • Commentary on a True Negative HIV Antibody Result with an Initially Incorrect Interpretation-A Diagnostic Conundrum in HIV Screening. (Nerenz RD) Clin Chem 2021 Oct 01;67(10):1322-1323 PMID: 34597371 SCOPUS ID: 2-s2.0-85117547646 10/02/2021    
  • Gamma Glutamyl Transferase Activity Has Limited Utility in Assessment of Alkaline Phosphatase Elevations. (Geno KA, Poore B, Cervinski MA, Nerenz RD) J Appl Lab Med 2021 Nov 01;6(6):1623-1627 PMID: 34414431 SCOPUS ID: 2-s2.0-85121477256 08/21/2021       2 Citations
  • A comparison of SARS-CoV-2 nucleocapsid and spike antibody detection using three commercially available automated immunoassays. (Poore B, Nerenz RD, Brodis D, Brown CI, Cervinski MA, Hubbard JA) Clin Biochem 2021 Sep;95:77-80 PMID: 34118242 PMCID: PMC8188801 SCOPUS ID: 2-s2.0-85108818274 06/13/2021       9 Citations
  • AACC Guidance Document on Laboratory Testing for the Assessment of Preterm Delivery. (Farnsworth C, Schuler EE, Woodworth A, Straseski J, Pschirrer ER, Nerenz RD) J Appl Lab Med 2021 Jul 07;6(4):1032-1044 PMID: 34076232 SCOPUS ID: 2-s2.0-85112119371 06/03/2021       3 Citations
  • Evaluation of Thyroid Function in Pregnant Women Using Automated Immunoassays. (Geno KA, Reed MS, Cervinski MA, Nerenz RD) Clin Chem 2021 Apr 29;67(5):772-780 PMID: 33928365 SCOPUS ID: 2-s2.0-85105050359 05/01/2021       6 Citations
  • Comparison of Two Automated Immunoassays for the Detection of SARS-CoV-2 Nucleocapsid Antibodies. (Hubbard JA, Geno KA, Khan J, Szczepiorkowski ZM, de Gijsel D, Ovalle AA, AlSalman AS, Gallagher TL, Johnston AA, Tibbetts AR, Vital SE, Cervinski MA, Nerenz RD) J Appl Lab Med 2021 Mar 01;6(2):429-440 PMID: 32976593 PMCID: PMC7543392 SCOPUS ID: 2-s2.0-85102657669 09/26/2020       9 Citations
  • Improved Recognition of 25-Hydroxyvitamin D2 by 2 Automated Immunoassays. (Geno KA, Tolan NV, Singh RJ, Nerenz RD) J Appl Lab Med 2020 Nov 01;5(6):1287-1295 PMID: 32529210 SCOPUS ID: 2-s2.0-85095800639 06/13/2020       3 Citations
  • The 2018 AACC/SYCL PhD Clinical Chemist Compensation Survey. (Bunch DR, El-Khoury JM, Colby J, Colon-Franco J, Hackenmueller SA, Olson KN, Cotten SW, Kampfrath T, Chittiprol S, Suh-Lailam B, French D, Isbell TS, Nerenz RD, Parnas ML, Tolan NV) J Appl Lab Med 2020 Mar 01;5(2):377-387 PMID: 32445390 SCOPUS ID: 2-s2.0-85107958602 05/24/2020       1 Citation
  • Clinical Validation of a 106-SNV MALDI-ToF MS Pharmacogenomic Panel. (Williams GR, Cook L, Lewis LD, Tsongalis GJ, Nerenz RD) J Appl Lab Med 2020 May 01;5(3):454-466 PMID: 32445367 SCOPUS ID: 2-s2.0-85111798083 05/24/2020       5 Citations
  • Direct-to-Consumer Testing: The Role of Laboratory Medicine Physicians and Scientists. (Tolan NV, Nerenz RD) Clin Lab Med 2020 Mar;40(1):ix-x PMID: 32008644 SCOPUS ID: 2-s2.0-85078421067 02/06/2020       2 Citations
  • Not Your Ordinary Rash. (Williams GR, Nerenz RD) Clin Chem 2019 Jun;65(6):733-737 PMID: 31138547 SCOPUS ID: 2-s2.0-85066490903 05/30/2019    
  • 5-Oxoproline concentrations in acute acetaminophen overdose. (Mullins ME, Jones MS, Nerenz RD, Schwarz ES, Dietzen DJ) Clin Toxicol (Phila) 2020 Jan;58(1):62-64 PMID: 31050299 SCOPUS ID: 2-s2.0-85065292798 05/03/2019       4 Citations
  • The Curious Case of an Isolated Positive Hepatitis B Surface Antigen Result. (Nerenz RD, Felty CC, Cervinski MA) Clin Chem 2019 Mar;65(3):499-500 PMID: 30819794 SCOPUS ID: 2-s2.0-85063593082 03/02/2019    
  • Improved Performance of Point-of-Care Human Chorionic Gonadotropin Pregnancy Device. (Farnsworth CW, Nerenz RD, Gronowski AM) Clin Chem 2018 Oct;64(10):1539-1541 PMID: 30068691 SCOPUS ID: 2-s2.0-85054832349 08/03/2018       1 Citation
  • Assessment of biotin interference with qualitative point-of-care hCG test devices. (Williams GR, Cervinski MA, Nerenz RD) Clin Biochem 2018 Mar;53:168-170 PMID: 29395091 SCOPUS ID: 2-s2.0-85041232136 02/06/2018       20 Citations
  • Pharmacogenetics of Opioid Use and Implications for Pain Management. (Nerenz RD, Tsongalis GJ) J Appl Lab Med 2018 Jan 01;2(4):622-632 PMID: 33636885 SCOPUS ID: 2-s2.0-85068237670 01/01/2018       12 Citations
  • Plumbing the Wastefulness of Zinc Protoporphyrin as a Pediatric Lead Screen. (Toth LN, Nerenz RD, Huyck KL, Cervinski MA) J Appl Lab Med 2017 Nov 01;2(3):451-454 PMID: 33636849 SCOPUS ID: 2-s2.0-85102161340 11/01/2017    
  • Analytical and Clinical Validation of Two Commercially Available Immunoassays Used in the Detection of TSHR Antibodies. (Kemble DJ, Jackson T, Morrison M, Cervinski MA, Nerenz RD) J Appl Lab Med 2017 Nov 01;2(3):345-355 PMID: 33636837 SCOPUS ID: 2-s2.0-85067915280 11/01/2017       7 Citations
  • Ready to Settle. (Shajani-Yi Z, Brunelle AA, Nerenz RD) Clin Chem 2017 Sep;63(9):1546-1547 PMID: 28848031 SCOPUS ID: 2-s2.0-85028500424 08/30/2017    
  • The Urine that Would Not Freeze. (Kemble DJ, Brunelle AA, Boulanger JA, Cervinski MA, Nerenz RD) J Appl Lab Med 2017 Jul 01;2(1):132-133 PMID: 33636960 SCOPUS ID: 2-s2.0-85102156189 07/01/2017    
  • Inappropriate Off-label Use of a Qualitative, Point-of-care hCG Device. (Nerenz RD, Gronowski AM, Grenache DG) West J Emerg Med 2017 Feb;18(2):324-325 PMID: 28265335 PMCID: PMC5321262 SCOPUS ID: 2-s2.0-85014805853 03/08/2017       1 Citation
  • Our Genome's "Dark Matter" Is the Next Frontier in Molecular Diagnostics. (Nerenz RD, Lefferts J) Clin Chem 2017 Mar;63(3):792-793 PMID: 28242839 SCOPUS ID: 2-s2.0-85014474781 03/01/2017       3 Citations
  • Omics in Reproductive Medicine: Application of Novel Technologies to Improve the IVF Success Rate. (Nerenz RD) Adv Clin Chem 2016;76:55-95 PMID: 27645816 SCOPUS ID: 2-s2.0-84999670100 09/21/2016       5 Citations
  • Analytical and Clinical Evaluation of the NOWDiagnostics ADEXUSDx Human Chorionic Gonadotropin Test Using Whole Blood. (Nerenz RD, Bell JR, Montes de Oca N, Short J, Mims T, Cleeton PA, Daniel Moore J, Humphries RL) J Appl Lab Med 2016 Jul 01;1(1):67-76 PMID: 33626807 SCOPUS ID: 2-s2.0-85014849841 07/01/2016       3 Citations
  • Characterizing urinary hCGβcf patterns during pregnancy. (Nerenz RD, Yarbrough ML, Stenman UH, Gronowski AM) Clin Biochem 2016 Jul;49(10-11):777-81 PMID: 27087510 SCOPUS ID: 2-s2.0-84973154496 04/19/2016       6 Citations
  • What's Wrong with These Pleural Fluid Samples? (Kukkar V, Miller VA, Richardson MA, Nerenz RD) Clin Chem 2016 Feb;62(2):415 PMID: 26823613 SCOPUS ID: 2-s2.0-84957069946 01/30/2016    
  • Estimating the hCGβcf in urine during pregnancy. (Nerenz RD, Butch AW, Woldemariam GA, Yarbrough ML, Grenache DG, Gronowski AM) Clin Biochem 2016 Feb;49(3):282-6 PMID: 26541857 SCOPUS ID: 2-s2.0-84957441104 11/07/2015       9 Citations
  • Evaluation of a semi-quantitative pregnancy device for susceptibility to interference caused by hCGβcf. (Nerenz RD, Butch AW, Ashby L, Woldemariam GA, Gronowski AM) Clin Biochem 2015 Aug;48(12):815-7 PMID: 25916816 SCOPUS ID: 2-s2.0-84938216127 04/29/2015       2 Citations
  • Analytical performance evaluation of the i-STAT Total β-human chorionic gonadotropin immunoassay. (Sowder AM, Yarbrough ML, Nerenz RD, Mitsios JV, Mortensen R, Gronowski AM, Grenache DG) Clin Chim Acta 2015 Jun 15;446:165-70 PMID: 25916696 SCOPUS ID: 2-s2.0-84928802805 04/29/2015       14 Citations
  • Confirmation of hCG Point-of-Care Qualitative Device Limitations in the Emergency Department. (Nerenz RD, Gronowski AM) J Emerg Med 2015 May;48(5):609-10 PMID: 25797934 SCOPUS ID: 2-s2.0-84929129135 03/24/2015       1 Citation
  • Assessing the risk of false negative point-of-care urinary human chorionic gonadotropin device results due to beta core fragment. (Gronowski AM, Nerenz RD) Clin Biochem 2015 Feb;48(3):97-8 PMID: 25578769 SCOPUS ID: 2-s2.0-84921795570 01/13/2015       7 Citations
  • Qualitative point-of-care human chorionic gonadotropin testing: can we defuse this ticking time bomb? (Nerenz RD, Gronowski AM) Clin Chem 2015 Mar;61(3):483-6 PMID: 25518858 SCOPUS ID: 2-s2.0-84921745223 12/19/2014       12 Citations
  • In reply. (Nerenz RD, Gronowski AM) Clin Chem 2014 Dec;60(12):1580-1 PMID: 25248571 SCOPUS ID: 2-s2.0-84925546149 09/25/2014    
  • Improved performance of point-of-care and over-the-counter qualitative human chorionic gonadotropin measurement devices. (Nerenz RD, Gronowski AM) Clin Chem 2014 Dec;60(12):1576-8 PMID: 25161145 SCOPUS ID: 2-s2.0-84925547316 08/28/2014       3 Citations
  • Screening method to evaluate point-of-care human chorionic gonadotropin (hCG) devices for susceptibility to the hook effect by hCG β core fragment: evaluation of 11 devices. (Nerenz RD, Song H, Gronowski AM) Clin Chem 2014 Apr;60(4):667-74 PMID: 24463559 SCOPUS ID: 2-s2.0-84897504380 01/28/2014       41 Citations
  • Premenopausal amenorrhea: what's in a number? (Nerenz RD, Jungheim ES, Lockwood CM) Clin Chem 2014 Jan;60(1):29-33; discussion 33-4 PMID: 24379309 SCOPUS ID: 2-s2.0-84891796840 01/01/2014       2 Citations
  • Point-of-care and over-the-counter qualitative human chorionic gonadotropin (hCG) devices remain susceptible to false-negative results caused by excess hCG β core fragment. (Nerenz RD, Gronowski AM) Clin Chem 2013 Nov;59(11):1672-4 PMID: 23985957 SCOPUS ID: 2-s2.0-84887057082 08/30/2013       12 Citations
  • Mouse Rankl expression is regulated in T cells by c-Fos through a cluster of distal regulatory enhancers designated the T cell control region. (Bishop KA, Coy HM, Nerenz RD, Meyer MB, Pike JW) J Biol Chem 2011 Jun 10;286(23):20880-91 PMID: 21487009 PMCID: PMC3121445 SCOPUS ID: 2-s2.0-79958016522 04/14/2011       47 Citations
  • Emerging regulatory paradigms for control of gene expression by 1,25-dihydroxyvitamin D3. (Pike JW, Meyer MB, Martowicz ML, Bishop KA, Lee SM, Nerenz RD, Goetsch PD) J Steroid Biochem Mol Biol 2010 Jul;121(1-2):130-5 PMID: 20214983 PMCID: PMC2894294 SCOPUS ID: 2-s2.0-77954763087 03/11/2010       50 Citations
  • Multifunctional enhancers regulate mouse and human vitamin D receptor gene transcription. (Zella LA, Meyer MB, Nerenz RD, Lee SM, Martowicz ML, Pike JW) Mol Endocrinol 2010 Jan;24(1):128-47 PMID: 19897601 PMCID: PMC2802900 SCOPUS ID: 2-s2.0-73549117448 11/10/2009       124 Citations
  • The enhanced hypercalcemic response to 20-epi-1,25-dihydroxyvitamin D3 results from a selective and prolonged induction of intestinal calcium-regulating genes. (Zella LA, Meyer MB, Nerenz RD, Pike JW) Endocrinology 2009 Aug;150(8):3448-56 PMID: 19423758 PMCID: PMC2717886 SCOPUS ID: 2-s2.0-67651154420 05/09/2009       25 Citations
  • An enhancer 20 kilobases upstream of the human receptor activator of nuclear factor-kappaB ligand gene mediates dominant activation by 1,25-dihydroxyvitamin D3. (Nerenz RD, Martowicz ML, Pike JW) Mol Endocrinol 2008 May;22(5):1044-56 PMID: 18202151 PMCID: PMC2366191 SCOPUS ID: 2-s2.0-43049098242 01/19/2008       43 Citations
  • Characterizing early events associated with the activation of target genes by 1,25-dihydroxyvitamin D3 in mouse kidney and intestine in vivo. (Meyer MB, Zella LA, Nerenz RD, Pike JW) J Biol Chem 2007 Aug 03;282(31):22344-52 PMID: 17556365 SCOPUS ID: 2-s2.0-34547942910 06/09/2007       91 Citations
  • Last update: 09/11/2024