Medical College of Wisconsin
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Sang H. Lee PhD

Sang H. Lee PhD profile photo picture

Professor

Institution: Medical College of Wisconsin
Department: Pharmacology and Toxicology
Program: Pharmacology

Member of the Neuroscience Research Center

View Curriculum Vitae

Publications (37)

  • Inter-neuronal signaling mediated by small extracellular vesicles: wireless communication? (Nieves Torres D, Lee SH) Front Mol Neurosci 2023;16:1187300 PMID: 37181650 PMCID: PMC10172472 SCOPUS ID: 2-s2.0-85159097504 05/14/2023       6 Citations
  • S-SCAM inhibits Axin-dependent synaptic function of GSK3β in a sex-dependent manner. (Kearney G, Grau D, Nieves Torres D, Shin SM, Lee SH) Sci Rep 2022 Mar 08;12(1):4090 PMID: 35260764 PMCID: PMC8904762 SCOPUS ID: 2-s2.0-85126076405 03/10/2022       1 Citation
  • Hydrostatic Pressure Controls Angiogenesis Through Endothelial YAP1 During Lung Regeneration. (Mammoto T, Hunyenyiwa T, Kyi P, Hendee K, Matus K, Rao S, Lee SH, Tabima DM, Chesler NC, Mammoto A) Front Bioeng Biotechnol 2022;10:823642 PMID: 35252132 PMCID: PMC8896883 SCOPUS ID: 2-s2.0-85125874454 03/08/2022       6 Citations
  • Aberrant expression of S-SCAM causes the loss of GABAergic synapses in hippocampal neurons. (Shin SM, Skaar S, Danielson E, Lee SH) Sci Rep 2020 Jan 09;10(1):83 PMID: 31919468 PMCID: PMC6952429 SCOPUS ID: 2-s2.0-85077694386 01/11/2020       11 Citations
  • Reciprocal control of excitatory synapse numbers by Wnt and Wnt inhibitor PRR7 secreted on exosomes. (Lee SH, Shin SM, Zhong P, Kim HT, Kim DI, Kim JM, Heo WD, Kim DW, Yeo CY, Kim CH, Liu QS) Nat Commun 2018 Aug 24;9(1):3434 PMID: 30143647 PMCID: PMC6109165 SCOPUS ID: 2-s2.0-85052238097 08/26/2018       38 Citations
  • Targeted knockout of a chemokine-like gene increases anxiety and fear responses. (Choi JH, Jeong YM, Kim S, Lee B, Ariyasiri K, Kim HT, Jung SH, Hwang KS, Choi TI, Park CO, Huh WK, Carl M, Rosenfeld JA, Raskin S, Ma A, Gecz J, Kim HG, Kim JS, Shin HC, Park DS, Gerlai R, Jamieson BB, Kim JS, Iremonger KJ, Lee SH, Shin HS, Kim CH) Proc Natl Acad Sci U S A 2018 Jan 30;115(5):E1041-E1050 PMID: 29339520 PMCID: PMC5798319 SCOPUS ID: 2-s2.0-85041206288 01/18/2018       39 Citations
  • Ottogi Inhibits Wnt/β-catenin Signaling by Regulating Cell Membrane Trafficking of Frizzled8. (Kim HT, Lee MS, Jeong YM, Ro H, Kim DI, Shin YH, Kim JE, Hwang KS, Choi JH, Bahn M, Lee JJ, Lee SH, Bae YK, Lee JS, Choi JK, Kim NS, Yeo CY, Kim CH) Sci Rep 2017 Oct 16;7(1):13278 PMID: 29038508 PMCID: PMC5643531 SCOPUS ID: 2-s2.0-85031779920 10/19/2017       4 Citations
  • S-SCAM, a rare copy number variation gene, induces schizophrenia-related endophenotypes in transgenic mouse model. (Zhang N, Zhong P, Shin SM, Metallo J, Danielson E, Olsen CM, Liu QS, Lee SH) J Neurosci 2015 Feb 04;35(5):1892-904 PMID: 25653350 PMCID: PMC4315826 SCOPUS ID: 2-s2.0-84922355999 02/06/2015       17 Citations
  • SynPAnal: software for rapid quantification of the density and intensity of protein puncta from fluorescence microscopy images of neurons. (Danielson E, Lee SH) PLoS One 2014;9(12):e115298 PMID: 25531531 PMCID: PMC4274056 SCOPUS ID: 2-s2.0-84919798286 12/23/2014       43 Citations
  • GKAP orchestrates activity-dependent postsynaptic protein remodeling and homeostatic scaling. (Shin SM, Zhang N, Hansen J, Gerges NZ, Pak DT, Sheng M, Lee SH) Nat Neurosci 2012 Dec;15(12):1655-66 PMID: 23143515 PMCID: PMC3804128 SCOPUS ID: 2-s2.0-84870494059 11/13/2012       106 Citations
  • Role of TARP interaction in S-SCAM-mediated regulation of AMPA receptors. (Danielson E, Metallo J, Lee SH) Channels (Austin) 2012;6(5):393-7 PMID: 22878254 PMCID: PMC3508780 SCOPUS ID: 2-s2.0-84878175337 08/11/2012       8 Citations
  • S-SCAM/MAGI-2 is an essential synaptic scaffolding molecule for the GluA2-containing maintenance pool of AMPA receptors. (Danielson E, Zhang N, Metallo J, Kaleka K, Shin SM, Gerges N, Lee SH) J Neurosci 2012 May 16;32(20):6967-80 PMID: 22593065 PMCID: PMC3365591 SCOPUS ID: 2-s2.0-84861121293 05/18/2012       41 Citations
  • Plk2 attachment to NSF induces homeostatic removal of GluA2 during chronic overexcitation. (Evers DM, Matta JA, Hoe HS, Zarkowsky D, Lee SH, Isaac JT, Pak DT) Nat Neurosci 2010 Oct;13(10):1199-207 PMID: 20802490 PMCID: PMC2947592 SCOPUS ID: 2-s2.0-77957279696 08/31/2010       56 Citations
  • The role of CaMKII as an F-actin-bundling protein crucial for maintenance of dendritic spine structure. (Okamoto K, Narayanan R, Lee SH, Murata K, Hayashi Y) Proc Natl Acad Sci U S A 2007 Apr 10;104(15):6418-23 PMID: 17404223 PMCID: PMC1851051 SCOPUS ID: 2-s2.0-34547523623 04/04/2007       240 Citations
  • Molecular determinants for the interaction between AMPA receptors and the clathrin adaptor complex AP-2. (Kastning K, Kukhtina V, Kittler JT, Chen G, Pechstein A, Enders S, Lee SH, Sheng M, Yan Z, Haucke V) Proc Natl Acad Sci U S A 2007 Feb 20;104(8):2991-6 PMID: 17289840 PMCID: PMC1815294 SCOPUS ID: 2-s2.0-33847321605 02/10/2007       76 Citations
  • Differential roles of Rap1 and Rap2 small GTPases in neurite retraction and synapse elimination in hippocampal spiny neurons. (Fu Z, Lee SH, Simonetta A, Hansen J, Sheng M, Pak DT) J Neurochem 2007 Jan;100(1):118-31 PMID: 17227435 SCOPUS ID: 2-s2.0-33846136109 01/18/2007       71 Citations
  • Subunit rules governing the sorting of internalized AMPA receptors in hippocampal neurons. (Lee SH, Simonetta A, Sheng M) Neuron 2004 Jul 22;43(2):221-36 PMID: 15260958 SCOPUS ID: 2-s2.0-3242656596 07/21/2004       228 Citations
  • Tyrosine phosphorylation of GluR2 is required for insulin-stimulated AMPA receptor endocytosis and LTD. (Ahmadian G, Ju W, Liu L, Wyszynski M, Lee SH, Dunah AW, Taghibiglou C, Wang Y, Lu J, Wong TP, Sheng M, Wang YT) EMBO J 2004 Mar 10;23(5):1040-50 PMID: 14976558 PMCID: PMC380981 SCOPUS ID: 2-s2.0-12144288368 02/21/2004       247 Citations
  • AMPA receptor trafficking and synaptic plasticity: major unanswered questions. (Sheng M, Hyoung Lee S) Neurosci Res 2003 Jun;46(2):127-34 PMID: 12767475 SCOPUS ID: 2-s2.0-0037614988 05/28/2003       68 Citations
  • Clathrin adaptor AP2 and NSF interact with overlapping sites of GluR2 and play distinct roles in AMPA receptor trafficking and hippocampal LTD. (Lee SH, Liu L, Wang YT, Sheng M) Neuron 2002 Nov 14;36(4):661-74 PMID: 12441055 SCOPUS ID: 2-s2.0-0037079062 11/21/2002       364 Citations
  • Mlo, a modulator of plant defense and cell death, is a novel calmodulin-binding protein. Isolation and characterization of a rice Mlo homologue. (Kim MC, Lee SH, Kim JK, Chun HJ, Choi MS, Chung WS, Moon BC, Kang CH, Park CY, Yoo JH, Kang YH, Koo SC, Koo YD, Jung JC, Kim ST, Schulze-Lefert P, Lee SY, Cho MJ) J Biol Chem 2002 May 31;277(22):19304-14 PMID: 11904292 SCOPUS ID: 2-s2.0-0037205430 03/21/2002       134 Citations
  • Identification of calmodulin isoform-specific binding peptides from a phage-displayed random 22-mer peptide library. (Choi JY, Lee SH, Park CY, Heo WD, Kim JC, Kim MC, Chung WS, Moon BC, Cheong YH, Kim CY, Yoo JH, Koo JC, Ok HM, Chi SW, Ryu SE, Lee SY, Lim CO, Cho MJ) J Biol Chem 2002 Jun 14;277(24):21630-8 PMID: 11901148 SCOPUS ID: 2-s2.0-0037077216 03/20/2002       30 Citations
  • Biochemical and morphological characterization of an intracellular membrane compartment containing AMPA receptors. (Lee SH, Valtschanoff JG, Kharazia VN, Weinberg R, Sheng M) Neuropharmacology 2001 Nov;41(6):680-92 PMID: 11640922 SCOPUS ID: 2-s2.0-0034800294 10/20/2001       57 Citations
  • AMPA receptor trafficking and the control of synaptic transmission. (Sheng M, Lee SH) Cell 2001 Jun 29;105(7):825-8 PMID: 11439178 SCOPUS ID: 2-s2.0-0035967909 07/06/2001       168 Citations
  • A novel cold-inducible zinc finger protein from soybean, SCOF-1, enhances cold tolerance in transgenic plants. (Kim JC, Lee SH, Cheong YH, Yoo CM, Lee SI, Chun HJ, Yun DJ, Hong JC, Lee SY, Lim CO, Cho MJ) Plant J 2001 Feb;25(3):247-59 PMID: 11208017 SCOPUS ID: 2-s2.0-0035119073 02/24/2001       276 Citations
  • Distinct molecular mechanisms and divergent endocytotic pathways of AMPA receptor internalization. (Lin JW, Ju W, Foster K, Lee SH, Ahmadian G, Wyszynski M, Wang YT, Sheng M) Nat Neurosci 2000 Dec;3(12):1282-90 PMID: 11100149 SCOPUS ID: 2-s2.0-0033695663 12/02/2000       417 Citations
  • Identification of a calmodulin-regulated soybean Ca(2+)-ATPase (SCA1) that is located in the plasma membrane. (Chung WS, Lee SH, Kim JC, Heo WD, Kim MC, Park CY, Park HC, Lim CO, Kim WB, Harper JF, Cho MJ) Plant Cell 2000 Aug;12(8):1393-407 PMID: 10948258 PMCID: PMC149111 SCOPUS ID: 2-s2.0-0033827635 08/19/2000       99 Citations
  • Differential regulation of Ca2+/calmodulin-dependent enzymes by plant calmodulin isoforms and free Ca2+ concentration. (Lee SH, Johnson JD, Walsh MP, Van Lierop JE, Sutherland C, Xu A, Snedden WA, Kosk-Kosicka D, Fromm H, Narayanan N, Cho MJ) Biochem J 2000 Aug 15;350 Pt 1(Pt 1):299-306 PMID: 10926857 PMCID: PMC1221255 SCOPUS ID: 2-s2.0-0034663566 08/06/2000       80 Citations
  • Growth of the NMDA receptor industrial complex. (Sheng M, Lee SH) Nat Neurosci 2000 Jul;3(7):633-5 PMID: 10862688 SCOPUS ID: 2-s2.0-0343192494 06/22/2000       44 Citations
  • Development of neuron-neuron synapses. (Lee SH, Sheng M) Curr Opin Neurobiol 2000 Feb;10(1):125-31 PMID: 10679427 SCOPUS ID: 2-s2.0-0033964412 02/19/2000       90 Citations
  • Competitive binding of calmodulin isoforms to calmodulin-binding proteins: implication for the function of calmodulin isoforms in plants. (Lee SH, Kim MC, Heo WD, Kim JC, Chung WS, Park CY, Park HC, Cheong YH, Kim CY, Lee KJ, Bahk JD, Lee SY, Cho MJ) Biochim Biophys Acta 1999 Aug 17;1433(1-2):56-67 PMID: 10446359 SCOPUS ID: 2-s2.0-0032813204 08/14/1999       44 Citations
  • Involvement of specific calmodulin isoforms in salicylic acid-independent activation of plant disease resistance responses. (Heo WD, Lee SH, Kim MC, Kim JC, Chung WS, Chun HJ, Lee KJ, Park CY, Park HC, Choi JY, Cho MJ) Proc Natl Acad Sci U S A 1999 Jan 19;96(2):766-71 PMID: 9892708 PMCID: PMC15211 SCOPUS ID: 2-s2.0-0033582172 01/20/1999       227 Citations
  • Reciprocal regulation of mammalian nitric oxide synthase and calcineurin by plant calmodulin isoforms. (Cho MJ, Vaghy PL, Kondo R, Lee SH, Davis JP, Rehl R, Heo WD, Johnson JD) Biochemistry 1998 Nov 10;37(45):15593-7 PMID: 9843363 SCOPUS ID: 2-s2.0-0032506166 12/08/1998       52 Citations
  • A new class II rice chitinase, Rcht2, whose induction by fungal elicitor is abolished by protein phosphatase 1 and 2A inhibitor. (Kim CY, Gal SW, Choe MS, Jeong SY, Lee SI, Cheong YH, Lee SH, Choi YJ, Han CD, Kang KY, Cho MJ) Plant Mol Biol 1998 Jun;37(3):523-34 PMID: 9617819 SCOPUS ID: 2-s2.0-2142773623 06/09/1998       38 Citations
  • Differential activation of NAD kinase by plant calmodulin isoforms. The critical role of domain I. (Lee SH, Seo HY, Kim JC, Heo WD, Chung WS, Lee KJ, Kim MC, Cheong YH, Choi JY, Lim CO, Cho MJ) J Biol Chem 1997 Apr 04;272(14):9252-9 PMID: 9083059 SCOPUS ID: 2-s2.0-0001281471 04/04/1997       66 Citations
  • Identification of a novel divergent calmodulin isoform from soybean which has differential ability to activate calmodulin-dependent enzymes. (Lee SH, Kim JC, Lee MS, Heo WD, Seo HY, Yoon HW, Hong JC, Lee SY, Bahk JD, Hwang I) J Biol Chem 1995 Sep 15;270(37):21806-12 PMID: 7665602 SCOPUS ID: 2-s2.0-0029101746 09/15/1995       126 Citations
  • Plasticity of hypothalamic motivational systems. (Wise RA) Science 1969 Aug 29;165(3896):929-30 PMID: 5798319 SCOPUS ID: 2-s2.0-0014694862 08/29/1969       14 Citations
    • Last update: 11/08/2023