Faculty Collaboration Database

Electrophysiological effects of lumbar dorsal root stimulation. Neurosurgery 1984 Jun;14(6):682-7

Date

06/01/1984

Pubmed ID

6087194

DOI

10.1227/00006123-198406000-00007

Scopus ID

2-s2.0-0021166187 (requires institutional sign-in at Scopus site)   3 Citations

Abstract

Electrical stimulation was applied to the L-5 and L-6 dorsal root ganglia of 14 monkeys with concurrent monitoring of cortical and intralaminar thalamic evoked potentials. Both responses were decreased by root stimulation, although cortical suppression required current levels 50 to 100% higher. The evoked potentials remained suppressed for periods of up to 60 minutes after 10- to 15-minute stimulation of the lumbar root electrodes. There was no increase in the duration of transmission block with longer stimulation periods. These results and available clinical data suggest that a local conduction block may be responsible for the pain relief produced by peripheral electrical stimulation. Further studies to identify more precisely the neural systems affected are required.

Author List

Myklebust JB, Maiman DJ, Larson SJ, Sances A Jr

Author

Dennis J. Maiman PhD, MD Emeritus Professor in the Neurosurgery department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Afferent Pathways
Animals
Electric Stimulation
Evoked Potentials, Somatosensory
Femoral Nerve
Ganglia, Spinal
Macaca
Motor Cortex
Nerve Fibers
Peroneal Nerve
Somatosensory Cortex
Synaptic Transmission
Thalamic Nuclei