Faculty Collaboration Database

Activation of complement and coagulation in juvenile dermatomyositis. Arthritis Rheum 1987 May;30(5):572-6

Date

05/01/1987

Pubmed ID

3109444

DOI

10.1002/art.1780300513

Scopus ID

2-s2.0-0023224813 (requires institutional sign-in at Scopus site)   28 Citations

Abstract

In patients with juvenile dermatomyositis (JDM), small vessel occlusion and thrombosis result in a decrease in the capillary: muscle fiber ratio. We studied 15 patients with JDM. Six of 7 patients with clinically active JDM had elevated levels of C3d. Moreover, concentrations of fibrinopeptide A and factor VIII-related antigen were significantly increased in patients with clinically active JDM.

Author List

Scott JP, Arroyave C

MESH terms used to index this publication - Major topics in bold

Adolescent
Adult
Antigens
Blood Coagulation
Child
Child, Preschool
Complement C3
Complement C3d
Dermatomyositis
Factor VIII
Female
Fibrinopeptide A
Humans
Male
von Willebrand Factor