Catalytic synthesis of tricyclic quinoline derivatives from the regioselective hydroamination and C-H bond activation reaction of benzocyclic amines and alkynes. J Am Chem Soc 2005 Apr 27;127(16):5782-3
Date
04/21/2005Pubmed ID
15839664DOI
10.1021/ja042318nScopus ID
2-s2.0-17744365003 (requires institutional sign-in at Scopus site) 112 CitationsAbstract
The cationic ruthenium-hydride complex [(PCy3)2(CO)(CH3CN)2RuH]+BF4- (1) was found to be an effective catalyst for the regioselective coupling reaction of benzocyclic amines and terminal alkynes to form the tricyclic quinoline derivatives. The scope of the reaction was explored by using the catalytic system Ru3(CO)12/NH4PF6. The catalytically active cationic ruthenium-acetylide complex [(PCy3)2(CO)(CH3CN)2RuCCPh]+BF4- was isolated from the reaction of 1 with phenylacetylene.
Author List
Yi CS, Yun SY, Guzei IAAuthor
Chae Yi PhD Professor, Inorganic and Organometallic Chemistry, Homogeneous Catalysis in the Chemistry department at Marquette UniversityMESH terms used to index this publication - Major topics in bold
AlkynesAmination
Amines
Benzene Derivatives
Catalysis
Molecular Structure
Organometallic Compounds
Quinolines
Ruthenium
