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Medical College of Wisconsin

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Stephanie S. Handler MD

Associate Professor

Institution: Medical College of Wisconsin
Department: Pediatrics
Division: Cardiology

Member of the Cardiovascular Research Center

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Publications (74)

Randomized, Placebo-Controlled Trial of Peri-Operative Treprostinil in Pediatric Patients Undergoing the Fontan Operation. (Sullivan RT, Handler SS, Arunamata AA, Ogawa MT, Liu E, Lu D, Martin E, Ramamoorthy C, Kameny R, Feinstein JA) Pulm Circ 2025 Jul;15(3):e70122 PMID: 40672982 PMCID: PMC12263512 SCOPUS ID: 2-s2.0-105010864819 07/17/2025

Pediatric Use of Inhaled Iloprost. (Handler SS, Abman SH, Varghese NP, Dunbar Ivy D) Pulm Circ 2025 Apr;15(2):e70115 PMID: 40547450 PMCID: PMC12182708 SCOPUS ID: 2-s2.0-105008822664 06/24/2025

Sociodemographic Disparities in Severity of Multisystem Inflammatory Syndrome in Children: The National Cross-Sectional MUltisystem Inflammatory Syndrome In Children (MUSIC) Study. (Lopez KN, Truong D, Anderson BR, Baker-Smith CM, Bradford TT, Dionne A, Dummer K, Forsha DE, Franklin WJ, Handler S, Harahsheh AS, Hasbani K, Liu I, Jone PN, Lang SM, McHugh KE, Oster M, Portman MA, Preminger T, Russell M, Sanil Y, Sexson Tejtel KS, Shakti D, Shea R, Trachtenberg F, Wang S, Wong JPP, Newburger JW, Pediatric Heart Network MUSIC investigators) J Pediatr 2025 Oct;285:114670 PMID: 40447131 SCOPUS ID: 2-s2.0-105008549119 05/31/2025

Pediatric Pulmonary Hypertension is Associated With Increased Circulating Levels of BMP 7 and CHIP. (Kirkpatrick EC, Handler S, Liegl M, Pan AY, Konduri GG, Gudausky TM, Afolayan AJ) Pulm Circ 2025 Apr;15(2):e70068 PMID: 40182212 PMCID: PMC11964942 SCOPUS ID: 2-s2.0-105002066994 04/04/2025

CMR Findings in the Long-Term Outcomes After Multisystem Inflammatory Syndrome in Children (MUSIC) Study. (Lang SM, Truong DT, Powell AJ, Kazlova V, Newburger JW, Awerbach JD, Binka E, Bradford TT, Cartoski M, Cheng A, DiLorenzo MP, Dionne A, Dorfman AL, Elias MD, Garuba O, Gerardin JF, Hasbani K, Jone PN, Lam CZ, Misra N, Morgan LM, Nutting A, Patel JK, Robinson JD, Schuchardt EL, Sexson Tejtel K, Singh GK, Slesnick TC, Trachtenberg F, Taylor MD, MUSIC Study Investigators) Circ Cardiovasc Imaging 2025 Sep;18(9):e017420 PMID: 40181776 PMCID: PMC12353833 SCOPUS ID: 2-s2.0-105002459407 04/04/2025 1 Citation

Hemodynamic Evaluation of Norwood Aortic Arch Geometry Compared to Native Arch Controls. (Blanch-Granada A, LaDisa JF Jr, Samyn MM, Cava JR, Handler SS, Gerardin JF, Goot B, Maadooliat M, Hraška V) J Biomech Eng 2025 May 01;147(5) PMID: 39992380 SCOPUS ID: 2-s2.0-105001681788 02/24/2025 1 Citation

Virtual Reality Curriculum Increases Pediatric Clerkship Students' Knowledge of Congenital Heart Disease. (Blonsky SE, Henning RE, Masterson EM, Axelrod DM, Handler SS, Yu S, Owens ST) Pediatr Cardiol 2025 Feb 06 PMID: 39912933 SCOPUS ID: 2-s2.0-85217694099 02/06/2025

Ethnic and racial differences in children and young people with respiratory and neurological post-acute sequelae of SARS-CoV-2: an electronic health record-based cohort study from the RECOVER Initiative (Rao S, Azuero-Dajud R, Lorman V, Landeo-Gutierrez J, Rhee KE, Ryu J, Kim C, Carmilani M, Gross RS, Mohandas S, Suresh S, Bailey LC, Castro V, Senathirajah Y, Esquenazi-Karonika S, Murphy S, Caddle S, Kleinman LC, Castro-Baucom L, Oliveira CR, Klein JD, Chung A, Cowell LG, Madlock-Brown C, Geary CR, Sills MR, Thorpe LE, Szmuszkovicz J, Tantisira KG, Snowden J, Irby K, Darden P, Dixon L, Evans D, Garbe C, Hobart-Porter L, Howard L, Hummel K, Krehbiel H, Spradlin H, Yount P, Elliott A, Adam G, Angal J, Barber M, Clark K, Dos Reis C, Freesemann M, Friedrich C, Hockett C, Johannsen R, Johnson-Vonk E, Kaiser C, Kruse A, Lang J, Lim P, McCoy M, Miller L, Petereit (Cerkovnik) S, RiChard (Werpy) J, Seiler J, Sundleaf B, Svendsen J, Trosper B, Vermeulen O, Young S, Palumbo A, Dabney S, Fahrner MC, Gallagher T, Martini K, McNally M, Vivensi Stiverson S, Kosut J, Balaraman V, Cheung JA, Hong TKF, Kalua S, Minami E, Siu A, Tong M, Teufel RJ, Atz A, Dantas M, Kasmarcak T, Milks K, Ross J, Ikomi C, Meyer M, Nguyen C, Pellicciotti G, Phan TL, Ravin K, Reynolds V, Strang A, Thacker D, Eckrich D, Goetter A, Katz C, Kowal K) eClinicalMedicine February 2025;80 SCOPUS ID: 2-s2.0-85214267549 02/01/2025 1 Citation

Six-Month Outcomes in the Long-Term Outcomes After the Multisystem Inflammatory Syndrome in Children Study. (Truong DT, Trachtenberg FL, Hu C, Pearson GD, Friedman K, Sabati AA, Dionne A, Oster ME, Anderson BR, Block J, Bradford TT, Campbell MJ, D'Addese L, Dummer KB, Elias MD, Forsha D, Garuba OD, Hasbani K, Hayes K, Hebson C, Jone PN, Krishnan A, Lang S, McCrindle BW, McHugh KE, Mitchell EC, Morrison T, Muniz JC, Payne RM, Portman MA, Russell MW, Sanil Y, Shakti D, Sharma K, Shea JR, Sykes M, Shekerdemian LS, Szmuszkovicz J, Thacker D, Newburger JW, MUSIC Study Investigators) JAMA Pediatr 2025 Mar 01;179(3):293-301 PMID: 39804656 PMCID: PMC11877180 SCOPUS ID: 2-s2.0-85216404137 01/13/2025 4 Citations

Actigraphy Study Endpoints to Reduce Sample Size and Facilitate Drug Development for Pediatric Pulmonary Arterial Hypertension. (Sun H, Stockbridge N, Ivy DD, Clark J, Bates A, Handler SS, Krishnan US, Mullen MP, Yung D, Hopper RK, Varghese NP, Avitabile CM, Fineman J, Austin ED, Freire G) J Pediatr 2025 Feb;277:114383 PMID: 39489285 SCOPUS ID: 2-s2.0-85210283058 11/04/2024 1 Citation

Characterizing Long COVID in Children and Adolescents. (Gross RS, Thaweethai T, Kleinman LC, Snowden JN, Rosenzweig EB, Milner JD, Tantisira KG, Rhee KE, Jernigan TL, Kinser PA, Salisbury AL, Warburton D, Mohandas S, Wood JC, Newburger JW, Truong DT, Flaherman VJ, Metz TD, Karlson EW, Chibnik LB, Pant DB, Krishnamoorthy A, Gallagher R, Lamendola-Essel MF, Hasson DC, Katz SD, Yin S, Dreyer BP, Carmilani M, Coombs K, Fitzgerald ML, Güthe N, Hornig M, Letts RJ, Peddie AK, Taylor BD, Balaraman V, Bogie A, Bukulmez H, Dozor AJ, Eckrich D, Elliott AJ, Evans DN, Farkas JS, Faustino EVS, Fischer L, Gaur S, Harahsheh AS, Hasan UN, Hsia DS, Huerta-Montañez G, Hummel KD, Kadish MP, Kaelber DC, Krishnan S, Kosut JS, Larrabee J, Lim PPC, Michelow IC, Oliveira CR, Raissy H, Rosario-Pabon Z, Ross JL, Sato AI, Stevenson MD, Talavera-Barber MM, Teufel RJ, Weakley KE, Zimmerman E, Bind MC, Chan J, Guan Z, Morse RE, Reeder HT, Akshoomoff N, Aschner JL, Bhattacharjee R, Cottrell LA, Cowan K, D'Sa VA, Fiks AG, Gennaro ML, Irby K, Khare M, Guttierrez JL, McCulloh RJ, Narang S, Ness-Cochinwala M, Nolan S, Palumbo P, Ryu J, Salazar JC, Selvarangan R, Stein CR, Werzberger A, Zempsky WT, Aupperle R, Baker FC, Banich MT, Barch DM, Baskin-Sommers A, Bjork JM, Bookheimer SY, Brown SA, Casey BJ, Chang L, Clark DB, Dale AM, Dapretto M, Ernst TM, Fair DA, Feldstein Ewing SW, Foxe JJ, Freedman EG, Friedman NP, Garavan H, Gee DG, Gonzalez R, Gray KM, Heitzeg MM, Herting MM, Jacobus J, Laird AR, Larson CL, Lisdahl KM, Luciana M, Luna B, Madden PAF, McGlade EC, Müller-Oehring EM, Nagel BJ, Neale MC, Paulus MP, Potter AS, Renshaw PF, Sowell ER, Squeglia LM, Tapert S, Uddin LQ, Wilson S, Yurgelun-Todd DA, Foulkes AS, Stockwell MS, RECOVER-Pediatrics Consortium, RECOVER-Pediatrics Group Authors) JAMA 2024 Aug 21;332(14):1174-88 PMID: 39196964 PMCID: PMC11339705 SCOPUS ID: 2-s2.0-85208796480 08/29/2024 39 Citations

Absorbable metal stents for vascular use in pediatric cardiology: progress and outlook. (McLennan DI, Maldonado JR, Foerster SR, Handler SS, LaDisa JF Jr, Gudausky TM, Guillory RJ 2nd) Front Cardiovasc Med 2024;11:1410305 PMID: 39165257 PMCID: PMC11334478 SCOPUS ID: 2-s2.0-85201532770 08/21/2024 6 Citations

Multimodal Assessment and Intramodal Comparison of Imaging Techniques for Pediatric Pulmonary Vein Stenosis with Pulmonary Hypertension. (Kieu V, Handler SS, Mitchell M, Pan AY, Zhang L, Kirkpatrick E) Pediatr Cardiol 2025 Jun;46(5):1180-1184 PMID: 38842557 SCOPUS ID: 2-s2.0-85195294865 06/06/2024

Researching COVID to enhance recovery (RECOVER) pediatric study protocol: Rationale, objectives and design. (Gross RS, Thaweethai T, Rosenzweig EB, Chan J, Chibnik LB, Cicek MS, Elliott AJ, Flaherman VJ, Foulkes AS, Gage Witvliet M, Gallagher R, Gennaro ML, Jernigan TL, Karlson EW, Katz SD, Kinser PA, Kleinman LC, Lamendola-Essel MF, Milner JD, Mohandas S, Mudumbi PC, Newburger JW, Rhee KE, Salisbury AL, Snowden JN, Stein CR, Stockwell MS, Tantisira KG, Thomason ME, Truong DT, Warburton D, Wood JC, Ahmed S, Akerlundh A, Alshawabkeh AN, Anderson BR, Aschner JL, Atz AM, Aupperle RL, Baker FC, Balaraman V, Banerjee D, Barch DM, Baskin-Sommers A, Bhuiyan S, Bind MC, Bogie AL, Bradford T, Buchbinder NC, Bueler E, Bükülmez H, Casey BJ, Chang L, Chrisant M, Clark DB, Clifton RG, Clouser KN, Cottrell L, Cowan K, D'Sa V, Dapretto M, Dasgupta S, Dehority W, Dionne A, Dummer KB, Elias MD, Esquenazi-Karonika S, Evans DN, Faustino EVS, Fiks AG, Forsha D, Foxe JJ, Friedman NP, Fry G, Gaur S, Gee DG, Gray KM, Handler S, Harahsheh AS, Hasbani K, Heath AC, Hebson C, Heitzeg MM, Hester CM, Hill S, Hobart-Porter L, Hong TKF, Horowitz CR, Hsia DS, Huentelman M, Hummel KD, Irby K, Jacobus J, Jacoby VL, Jone PN, Kaelber DC, Kasmarcak TJ, Kluko MJ, Kosut JS, Laird AR, Landeo-Gutierrez J, Lang SM, Larson CL, Lim PPC, Lisdahl KM, McCrindle BW, McCulloh RJ, McHugh K, Mendelsohn AL, Metz TD, Miller J, Mitchell EC, Morgan LM, Müller-Oehring EM, Nahin ER, Neale MC, Ness-Cochinwala M, Nolan SM, Oliveira CR, Osakwe O, Oster ME, Payne RM, Portman MA, Raissy H, Randall IG, Rao S, Reeder HT, Rosas JM, Russell MW, Sabati AA, Sanil Y, Sato AI, Schechter MS, Selvarangan R, Sexson Tejtel SK, Shakti D, Sharma K, Squeglia LM, Srivastava S, Stevenson MD, Szmuszkovicz J, Talavera-Barber MM, Teufel RJ 2nd, Thacker D, Trachtenberg F, Udosen MM, Warner MR, Watson SE, Werzberger A, Weyer JC, Wood MJ, Yin HS, Zempsky WT, Zimmerman E, Dreyer BP, RECOVER-Pediatric Consortium) PLoS One 2024;19(5):e0285635 PMID: 38713673 PMCID: PMC11075869 SCOPUS ID: 2-s2.0-85192583721 05/07/2024 7 Citations

Actigraphy methodology in the Kids Mod PAH trial: Physical activity as a functional endpoint in pediatric clinical trials. (Avitabile CM, Krishnan US, Yung D, Handler SS, Varghese N, Bates A, Fineman J, Sullivan R, Friere G, Austin E, Mullen MP, Pereira C, Christensen EJ, Yenokyan G, Collaco JM, Abman SH, Romer L, Dunbar Ivy D, Rosenzweig EB) Pulm Circ 2024 Jan;14(1):e12339 PMID: 38464344 PMCID: PMC10923039 SCOPUS ID: 2-s2.0-85187422793 03/11/2024 1 Citation

Effect of Virtual Aortic Arch Reconstruction After Norwood Procedure on Cardiac Function, Energy Efficiency, and Wall Shear Stress from Multiscale Simulations (Blanch-Granada A, Samyn MM, Handler SS, Gerardin JF, Goot B, Hraška V, Cava JR, LaDisa JF) Current Cardiovascular Imaging Reports December 2023;16(12):117-127 SCOPUS ID: 2-s2.0-85177741744 12/01/2023 2 Citations

Kids Mod PAH trial: A multicenter trial comparing mono- versus duo-therapy for initial treatment of pediatric pulmonary hypertension. (Collaco JM, Abman SH, Austin ED, Avitabile CM, Bates A, Fineman JR, Freire GA, Handler SS, Ivy DD, Krishnan US, Mullen MP, Varghese NP, Yung D, Nies MK, Everett AD, Zimmerman KO, Simmons W, Chakraborty H, Yenokyan G, Newell-Sturdivant A, Christensen E, Eyzaguirre LM, Hanley DF, Rosenzweig EB, Romer LH) Pulm Circ 2023 Oct;13(4):e12305 PMID: 37915400 PMCID: PMC10617301 SCOPUS ID: 2-s2.0-85175630535 11/02/2023 7 Citations

Use of the Transcultural Integrative Ethical Decision-Making Model in the Care of a Rohingya Infant With Hypoplastic Left Heart Syndrome (Boeding S, Aguilera V, Smith J, Handler S, Snyder J, Kroll K) Ethical Human Psychology and Psychiatry 1 October 2023;25(2):135-151 SCOPUS ID: 2-s2.0-85176256867 10/01/2023

The Use of Virtual Reality Learning on Transition Education in Adolescents with Congenital Heart Disease. (Kieu V, Sumski C, Cohen S, Reinhardt E, Axelrod DM, Handler SS) Pediatr Cardiol 2023 Dec;44(8):1856-1860 PMID: 37676275 SCOPUS ID: 2-s2.0-85169901832 09/07/2023 6 Citations

Measurement of Physical Activity by Actigraphy in Infants and Young Children with Pulmonary Arterial Hypertension. (Avitabile CM, Yung D, Handler S, Hopper RK, Fineman J, Freire G, Varghese N, Mullen MP, Krishnan US, Austin E, Silveira L, Ivy DD) J Pediatr 2023 Nov;262:113639 PMID: 37517653 PMCID: PMC11164018 SCOPUS ID: 2-s2.0-85168526623 07/31/2023 7 Citations

Editorial: Advances in the care of the pediatric pulmonary hypertension patient: from the neonate to the adolescent-young adult patient. (Avitabile CM, Hopper RK, Handler SS, Bates A) Front Pediatr 2023;11:1220070 PMID: 37303755 PMCID: PMC10248507 SCOPUS ID: 2-s2.0-85161386019 06/12/2023 1 Citation

Screening for traumatic stress in children and adolescents with congenital heart disease (Konkel T, Kroll KH, Goertz MT, Lavoie J, Bagli SP, Kogutkiewicz K, Kostroski R, Scott L, Stoll P, Andres J, Saudek D, Handler SS, Brosig CL) Progress in Pediatric Cardiology March 2023;68 SCOPUS ID: 2-s2.0-85142746033 03/01/2023 1 Citation

Multicenter review of a tadalafil suspension formulation for infants and children with pulmonary hypertension: A North American experience. (Youssef DE, Handler SS, Richards SM, Sheppard CA, Smith J, Tillman K, Pietrosanu M, Kirkpatrick E, Bates A) Front Pediatr 2023;11:1055131 PMID: 36776903 PMCID: PMC9909267 SCOPUS ID: 2-s2.0-85147946265 02/14/2023 3 Citations

Examination of Adverse Reactions After COVID-19 Vaccination Among Patients With a History of Multisystem Inflammatory Syndrome in Children. (Elias MD, Truong DT, Oster ME, Trachtenberg FL, Mu X, Jone PN, Mitchell EC, Dummer KB, Sexson Tejtel SK, Osakwe O, Thacker D, Su JA, Bradford TT, Burns KM, Campbell MJ, Connors TJ, D'Addese L, Forsha D, Frosch OH, Giglia TM, Goodell LR, Handler SS, Hasbani K, Hebson C, Krishnan A, Lang SM, McCrindle BW, McHugh KE, Morgan LM, Payne RM, Sabati A, Sagiv E, Sanil Y, Serrano F, Newburger JW, Dionne A, Pediatric Heart Network MUSIC Study Investigators) JAMA Netw Open 2023 Jan 03;6(1):e2248987 PMID: 36595296 PMCID: PMC9857632 SCOPUS ID: 2-s2.0-85145431182 01/04/2023 16 Citations

Impact of Reintervention During Stage 1 Palliation Hospitalization: A National, Multicenter Study. (Handler SS, Chan T, Ghanayem NS, Rudd N, Wright G, Visotcky A, Sparapani R, Mitchell ME, Hoffman GM, Frommelt MA) Ann Thorac Surg 2023 Apr;115(4):975-981 PMID: 36306859 SCOPUS ID: 2-s2.0-85142376895 10/29/2022 3 Citations

Clinical Variables Associated with Pre-Fontan Aortopulmonary Collateral Burden. (Segar DE, Pan AY, McLennan DI, Kindel SJ, Handler SS, Ginde S, Woods RK, Goot BH, Spearman AD) Pediatr Cardiol 2023 Jan;44(1):228-236 PMID: 36156171 PMCID: PMC10155213 SCOPUS ID: 2-s2.0-85138742613 09/27/2022 3 Citations

Pulmonary Hypertension in Children with Down Syndrome: Results from the Pediatric Pulmonary Hypertension Network Registry. (Hopper RK, Abman SH, Elia EG, Avitabile CM, Yung D, Mullen MP, Austin ED, Bates A, Handler SS, Feinstein JA, Ivy DD, Kinsella JP, Mandl KD, Raj JU, Sleeper LA, Pediatric Pulmonary Hypertension Network Investigators) J Pediatr 2023 Jan;252:131-140.e3 PMID: 36027975 PMCID: PMC10195185 SCOPUS ID: 2-s2.0-85139075416 08/27/2022 16 Citations

Intranasal dexmedetomidine for transthoracic echocardiography in infants with shunt-dependent single ventricle heart disease. (Ellepola CD, Handler SS, Frommelt M, Saudek DE, Scott J, Hoffman G, Frommelt PC) Cardiol Young 2023 Aug;33(8):1327-1331 PMID: 35938539 SCOPUS ID: 2-s2.0-85169651954 08/09/2022 1 Citation

Subcutaneous Treprostinil Improves Surgical Candidacy for Next Stage Palliation in Single Ventricle Patients With High-Risk Hemodynamics. (Sullivan RT, Handler SS, Feinstein JA, Ogawa M, Liu E, Ma M, Hopper RK, Norris J, Hollander SA, Chen S) Semin Thorac Cardiovasc Surg 2023;35(4):733-743 PMID: 35931345 SCOPUS ID: 2-s2.0-85138528914 08/06/2022 5 Citations

Abnormal platelet aggregation in pediatric pulmonary hypertension. (Handler SS, Jin J, Ogawa MT, Feinstein JA, Lo C) Pulm Circ 2022 Jul;12(3):e12104 PMID: 35864911 PMCID: PMC9294293 SCOPUS ID: 2-s2.0-85138896295 07/23/2022 4 Citations

Assessing growth of infants with chylothorax receiving fortified skimmed human breast milk. (Clark B, Froh M, Karls C, Feuling MB, Goday P, Uhing M, Handler SS, Nghiem-Rao TH, Polzin E) Nutr Clin Pract 2023 Feb;38(1):199-203 PMID: 35780315 PMCID: PMC10448868 SCOPUS ID: 2-s2.0-85133301246 07/04/2022 2 Citations

Cumulative In-Hospital Costs Associated With Single-Ventricle Palliation (O'Byrne ML, McHugh KE, Huang J, Song L, Griffis H, Anderson BR, Bucholz EM, Chanani NK, Elhoff JJ, Handler SS, Jacobs JP, Li JS, Lewis AB, McCrindle BW, Pinto NM, Sassalos P, Spar DS, Pasquali SK, Glatz AC) JACC: Advances June 2022;1(2) SCOPUS ID: 2-s2.0-85144082864 06/01/2022 5 Citations

Significance of α-Myosin Heavy Chain (MYH6) Variants in Hypoplastic Left Heart Syndrome and Related Cardiovascular Diseases. (Anfinson M, Fitts RH, Lough JW, James JM, Simpson PM, Handler SS, Mitchell ME, Tomita-Mitchell A) J Cardiovasc Dev Dis 2022 May 03;9(5) PMID: 35621855 PMCID: PMC9147009 SCOPUS ID: 2-s2.0-85130146333 05/28/2022 23 Citations

Cumulative In-Hospital Costs Associated With Single-Ventricle Palliation. (O'Byrne ML, McHugh KE, Huang J, Song L, Griffis H, Anderson BR, Bucholz EM, Chanani NK, Elhoff JJ, Handler SS, Jacobs JP, Li JS, Lewis AB, McCrindle BW, Pinto NM, Sassalos P, Spar DS, Pasquali SK, Glatz AC) JACC Adv 2022 Jun;1(2):100029 PMID: 38939312 PMCID: PMC11198056 SCOPUS ID: 2-s2.0-85144082864 05/26/2022 5 Citations

Building a dedicated pediatric pulmonary hypertension program: A consensus statement from the pediatric pulmonary hypertension network. (Handler SS, Varghese NP, Rosenzweig EB, Yung D, Krishnan U, Whalen E, Bates A, Avitabile CM, Jackson EO, Hirsch R, Fineman J, Abman SH, Pediatric Pulmonary Hypertension Network (PPHNet)) Pulm Circ 2022 Jan;12(1):e12031 PMID: 35506071 PMCID: PMC9052968 SCOPUS ID: 2-s2.0-85127255305 05/05/2022 1 Citation

Virtual reality curriculum increases paediatric residents' knowledge of CHDs. (Lim TR, Wilson HC, Axelrod DM, Werho DK, Handler SS, Yu S, Afton K, Lowery R, Mullan PB, Cooke J, Owens ST) Cardiol Young 2023 Mar;33(3):410-414 PMID: 35466894 SCOPUS ID: 2-s2.0-85129656272 04/26/2022 9 Citations

A multimedia paediatric cardiology assessment tool for medical students and general paediatric trainees: development and validation. (Wilson HC, Lim TR, Axelrod DM, Werho DK, Handler SS, Mullan PB, Cooke JM, Owens ST) Cardiol Young 2023 Mar;33(3):444-448 PMID: 35411842 SCOPUS ID: 2-s2.0-85129103666 04/13/2022 3 Citations

Factors Associated with Inability to Discharge After Stage 1 Palliation for Single Ventricle Heart Disease: An Analysis of the National Pediatric Cardiology Quality Improvement Collaborative Database. (Luna AO, Kuhnell P, Wooton S, Handler SS, Wright G, Hammel J, Tweddell JS, Chan T) Pediatr Cardiol 2022 Aug;43(6):1298-1310 PMID: 35243519 SCOPUS ID: 2-s2.0-85125525020 03/05/2022 3 Citations

Cardiac Catheterization and Hemodynamics in a Multicenter Cohort of Children with Pulmonary Hypertension. (Rosenzweig EB, Bates A, Mullen MP, Abman SH, Austin ED, Everett A, Fineman J, Feinstein J, Hopper RK, Kinsella JP, Krishnan US, Lu M, Mandl KD, Raj JU, Varghese N, Yung D, Handler SS, Sleeper LA) Ann Am Thorac Soc 2022 Jun;19(6):1000-1012 PMID: 35049414 PMCID: PMC9169121 SCOPUS ID: 2-s2.0-85131268686 01/21/2022 16 Citations

Pulmonary Vein Stenosis: Moving From Past Pessimism to Future Optimism. (McLennan DI, Solano ECR, Handler SS, Lincoln J, Mitchell ME, Kirkpatrick EC) Front Pediatr 2021;9:747812 PMID: 34676188 PMCID: PMC8524035 SCOPUS ID: 2-s2.0-85117473817 10/23/2021 15 Citations

The NHLBI Study on Long-terM OUtcomes after the Multisystem Inflammatory Syndrome In Children (MUSIC): Design and Objectives. (Truong DT, Trachtenberg FL, Pearson GD, Dionne A, Elias MD, Friedman K, Hayes KH, Mahony L, McCrindle BW, Oster ME, Pemberton V, Powell AJ, Russell MW, Shekerdemian LS, Son MB, Taylor M, Newburger JW, MUSIC Study Investigators (Supplement 1)) Am Heart J 2022 Jan;243:43-53 PMID: 34418362 PMCID: PMC8710361 SCOPUS ID: 2-s2.0-85122487901 08/22/2021 25 Citations

Stability Determination of an Extemporaneously Compounded Ambrisentan Suspension by High Performance Liquid Chromatography Analysis. (Cramer J, Bevry M, Handler S, Tillman K, Abourashed EA) J Pediatr Pharmacol Ther 2021;26(3):265-270 PMID: 33833628 PMCID: PMC8021248 SCOPUS ID: 2-s2.0-85104684194 04/10/2021 1 Citation

A Case of Alveolar Capillary Dysplasia with Misalignment of the Pulmonary Veins (ACD/MPV): The Importance of Early Genetic Testing (Callan EA, Geddes G, Konduri GG, Handler S) Journal of Neonatology March 2021;35(1):38-41 SCOPUS ID: 2-s2.0-85101927936 03/01/2021 3 Citations

Diazoxide-associated pulmonary hypertension in a patient with noncompaction cardiomyopathy. (Sullivan RT, Tillman KA, Kindel SJ, Handler SS) Pulm Circ 2021;11(1):2045894020987117 PMID: 33614015 PMCID: PMC7869162 SCOPUS ID: 2-s2.0-85100548909 02/23/2021 3 Citations

Role of echocardiographic scoring systems in predicting successful biventricular versus univentricular palliation in neonates with critical aortic stenosis. (Sachdeva S, Kuhn E, Frommelt PC, Handler S) Cardiol Young 2020 Nov;30(11):1702-1707 PMID: 32880254 SCOPUS ID: 2-s2.0-85091424062 09/04/2020 7 Citations

Proceedings From the 2019 Stanford Single Ventricle Scientific Summit: Advancing Science for Single Ventricle Patients: From Discovery to Clinical Applications. (Reddy S, Handler SS, Wu S, Rabinovitch M, Wright G) J Am Heart Assoc 2020 Apr 07;9(7):e015871 PMID: 32188306 PMCID: PMC7428620 SCOPUS ID: 2-s2.0-85082035873 03/20/2020 13 Citations

Acute vasoreactivity testing in pediatric idiopathic pulmonary arterial hypertension: an international survey on current practice (Caicedo L, Hopper R, Garcia Aguilar H, Ivy D, Haag D, Fineman J, Humpl T, Al-Tamimi O, Feinstein JA, Berger R, Rosenzweig E, Kashour T, Diaz GF, Mendoza A, Krishnan U, Bobhate P, Handler S, Lopes AA, Kumar Rahit M, Barward P, Labrandero de Lera C, Adatia I, Moledina S, Abman S, Cerro MJd) Pulmonary Circulation October 2019;9(4) SCOPUS ID: 2-s2.0-85075357923 10/01/2019 9 Citations

Subcutaneous and Intravenous Treprostinil Pharmacokinetics in Children With Pulmonary Vascular Disease. (Hall K, Ogawa M, Sakarovitch C, Hopper RK, Adamson GT, Hanna B, Ivy DD, Miller-Reed K, Yung D, McCarthy E, Siehr-Handler SL, Feinstein JA) J Cardiovasc Pharmacol 2019 Jun;73(6):383-393 PMID: 31162247 SCOPUS ID: 2-s2.0-85067179174 06/05/2019 9 Citations

EXPRESS: Acute Vasoreactivity Testing in Pediatric Idiopathic Pulmonary Arterial Hypertension: an international Survey on Current Practice. (Caicedo L, Hopper RK, Garcia H, Ivy DD, Haag D, Fineman J, Humpi T, Al-Tamimi O, Feinstein J, Berger RM, Berman-Rosenzweig E, Kashour T, Diaz GF, Mendoza A, Bobhate P, Handler S, Lopes AA, Barwad P, Kumar Rahit M, Krishnan U, Adatia ITK, Moledina S, Abman S, Cerro Marin MJD) Pulm Circ 2019 May 30;9(4):2045894019857533 PMID: 31144586 PMCID: PMC6886286 SCOPUS ID: 2-s2.0-85075357923 05/31/2019 9 Citations

Histopathologic and Genetic Features of Alveolar Capillary Dysplasia with Atypical Late Presentation and Prolonged Survival. (Edwards JJ, Murali C, Pogoriler J, Frank DB, Handler SS, Deardorff MA, Hopper RK) J Pediatr 2019 Jul;210:214-219.e2 PMID: 30853201 PMCID: PMC6592752 SCOPUS ID: 2-s2.0-85062429212 03/12/2019 39 Citations

Pulmonary Vascular Disease in the Single-Ventricle Patient: Is it Really Pulmonary Hypertension and if So, How and When Should We Treat it? (Handler SS, Feinstein JA) Advances in Pulmonary Hypertension 03/01/2019

Assessment of quality of life in pediatric patients with pulmonary hypertension. (Handler SS, Hallis BJ, Tillman KA, Krolikowski M, Kuhn EM, Kirkpatrick EC, Brosig CL) Pulm Circ 2019;9(3):2045894018822985 PMID: 30562156 PMCID: PMC6607578 SCOPUS ID: 2-s2.0-85068370934 12/19/2018 11 Citations

Hybrid Palliation as a Bridge to Biventricular Repair in Critical Aortic Stenosis With Coarctation. (Handler SS, Buelow M, Bergstrom C, Frommelt PC, Hraska V) Ann Thorac Surg 2019 Jun;107(6):e395-e396 PMID: 30414828 SCOPUS ID: 2-s2.0-85065823382 11/12/2018 1 Citation

Single center experience with the Potts shunt in severe pulmonary arterial hypertension (Kirkpatrick EC, Handler SS, Foerster S, Gudausky T, Tillman K, Mitchell M) Progress in Pediatric Cardiology March 2018;48:111-115 SCOPUS ID: 2-s2.0-85039698817 03/01/2018 2 Citations

Tetralogy of fallot with and without pulmonary atresia (Handler SS, Ginde S, Bergstrom CP, Woods RK) Critical Heart Disease in Infants and Children 1 January 2018:705-719.e4 SCOPUS ID: 2-s2.0-85082270849 01/01/2018 1 Citation

Subcutaneous treprostinil in pediatric patients with failing single-ventricle physiology. (Handler SS, Ogawa MT, Hopper RK, Sakarovitch C, Feinstein JA) J Heart Lung Transplant 2017 Sep 14 PMID: 29126699 SCOPUS ID: 2-s2.0-85032986706 11/12/2017 10 Citations

Hemodynamic Effects of Phenylephrine, Vasopressin, and Epinephrine in Children With Pulmonary Hypertension: A Pilot Study. (Siehr SL, Feinstein JA, Yang W, Peng LF, Ogawa MT, Ramamoorthy C) Pediatr Crit Care Med 2016 May;17(5):428-37 PMID: 27144689 SCOPUS ID: 2-s2.0-84966551148 05/06/2016 47 Citations

Outpatient Subcutaneous Treprostinil for Pediatric Single Ventricle Patients (Siehr SL, Ogawa M, Romfh A, Rosenthal DN, Feinstein JA) The Journal of Heart and Lung Transplantation 04/01/2016

Exploring the Role of Polycythemia in Patients With Cyanosis After Palliative Congenital Heart Surgery. (Siehr SL, Shi S, Hao S, Hu Z, Jin B, Hanley F, Reddy VM, McElhinney DB, Ling XB, Shin AY) Pediatr Crit Care Med 2016 Mar;17(3):216-22 PMID: 26825044 SCOPUS ID: 2-s2.0-84961211208 01/31/2016 10 Citations

Training Pathways in Pediatric Cardiac Intensive Care: Proceedings From the 10th International Conference of the Pediatric Cardiac Intensive Care Society. (Anand V, Kwiatkowski DM, Ghanayem NS, Axelrod DM, DiNardo J, Klugman D, Krishnamurthy G, Siehr S, Stromberg D, Yates AR, Roth SJ, Cooper DS) World J Pediatr Congenit Heart Surg 2016 Jan;7(1):81-8 PMID: 26714998 SCOPUS ID: 2-s2.0-84996225271 12/31/2015 18 Citations

Mitral Stenosis and Aortic Atresia--A Risk Factor for Mortality After the Modified Norwood Operation in Hypoplastic Left Heart Syndrome. (Siehr SL, Maeda K, Connolly AA, Tacy TA, Reddy VM, Hanley FL, Perry SB, Wright GE) Ann Thorac Surg 2016 Jan;101(1):162-7 PMID: 26602002 SCOPUS ID: 2-s2.0-84955462274 11/26/2015 31 Citations

COCATS 4: Securing the Future of Cardiovascular Medicine. (Sinha SS, Julien HM, Krim SR, Ijioma NN, Baron SJ, Rock AJ, Siehr SL, Cullen MW, American College of Cardiology Fellow-in-Training Section Leadership Council) J Am Coll Cardiol 2015 May 05;65(17):1907-14 PMID: 25945751 SCOPUS ID: 2-s2.0-84929193259 05/07/2015 28 Citations

Reported sildenafil side effects in pediatric pulmonary hypertension patients. (Siehr SL, McCarthy EK, Ogawa MT, Feinstein JA) Front Pediatr 2015;3:12 PMID: 25806361 PMCID: PMC4353247 SCOPUS ID: 2-s2.0-84940895521 03/26/2015 21 Citations

Ebstein anomaly and Trisomy 21: A rare association. (Siehr SL, Punn R, Priest JR, Lowenthal A) Ann Pediatr Cardiol 2014 Jan;7(1):67-9 PMID: 24701093 PMCID: PMC3959069 SCOPUS ID: 2-s2.0-84894172836 04/05/2014 4 Citations

Outcomes following cardiac catheterization after congenital heart surgery. (Siehr SL, Martin MH, Axelrod D, Efron B, Peng L, Roth SJ, Perry S, Shin AY) Catheter Cardiovasc Interv 2014 Oct 01;84(4):622-8 PMID: 24659225 SCOPUS ID: 2-s2.0-84927697853 03/25/2014 15 Citations

Orthotopic heart transplantation in two infants with histiocytoid cardiomyopathy and left ventricular non-compaction. (Siehr SL, Bernstein D, Yeh J, Berry GJ, Rosenthal DN, Hollander SA) Pediatr Transplant 2013 Nov;17(7):E165-7 PMID: 24099092 SCOPUS ID: 2-s2.0-84885395108 10/09/2013 5 Citations

Incidence and risk factors of complete atrioventricular block after operative ventricular septal defect repair. (Siehr SL, Hanley FL, Reddy VM, Miyake CY, Dubin AM) Congenit Heart Dis 2014;9(3):211-5 PMID: 23764088 SCOPUS ID: 2-s2.0-84902544830 06/15/2013 40 Citations

Home monitoring program reduces interstage mortality after the modified Norwood procedure. (Siehr SL, Norris JK, Bushnell JA, Ramamoorthy C, Reddy VM, Hanley FL, Wright GE) J Thorac Cardiovasc Surg 2014 Feb;147(2):718-23.e1 PMID: 23663957 SCOPUS ID: 2-s2.0-84892367249 05/15/2013 73 Citations

Children with pulmonary arterial hypertension and prostanoid therapy: long-term hemodynamics. (Siehr SL, Ivy DD, Miller-Reed K, Ogawa M, Rosenthal DN, Feinstein JA) J Heart Lung Transplant 2013 May;32(5):546-52 PMID: 23453572 PMCID: PMC3760159 SCOPUS ID: 2-s2.0-84876046035 03/05/2013 59 Citations

Electrical and mechanical dyssynchrony in pediatric pulmonary hypertension. (Hill AC, Maxey DM, Rosenthal DN, Siehr SL, Hollander SA, Feinstein JA, Dubin AM) J Heart Lung Transplant 2012 Aug;31(8):825-30 PMID: 22682994 SCOPUS ID: 2-s2.0-84863325667 06/12/2012 16 Citations

Clinical usefulness of a novel C1q assay to detect immunoglobulin G antibodies capable of fixing complement in sensitized pediatric heart transplant patients. (Chin C, Chen G, Sequeria F, Berry G, Siehr S, Bernstein D, Rosenthal D, Reinhartz O, Tyan D) J Heart Lung Transplant 2011 Feb;30(2):158-63 PMID: 20951058 SCOPUS ID: 2-s2.0-78650960273 10/19/2010 189 Citations

Hypersensitivity reactions to aprotinin re-exposure in paediatric surgery. (Siehr S, Stuth E, Tweddell J, Hoffman G, Troshynski T, Jones D, Mitchell M, Ghanayem N) Eur J Cardiothorac Surg 2010 Feb;37(2):307-11 PMID: 19767215 SCOPUS ID: 2-s2.0-74249101769 09/22/2009 10 Citations

Early cavopulmonary anastomosis after Norwood procedure results in excellent Fontan outcome. (Jaquiss RD, Siehr SL, Ghanayem NS, Hoffman GM, Fedderly RT, Cava JR, Mussatto KA, Tweddell JS) Ann Thorac Surg 2006 Oct;82(4):1260-5; discussion 1265-6 PMID: 16996918 SCOPUS ID: 2-s2.0-33748748733 09/26/2006 41 Citations

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Profiles for MCW, MU, MSOE, UWM, BCW, CW, Froedtert, and VA Faculty

Stephanie S. Handler MD

Associate Professor

Publications (74)