CURRICULUM VITAE
Melinda R. Dwinell PhD
Melinda R. Dwinell PhD
Center Associate Director, Associate Professor
Department of Physiology
Department of Physiology
OFFICE ADDRESS: |
Health Research Center |
8701 Watertown Plank Rd |
Milwaukee, WI 53226 |
EDUCATION: |
09/1986 - 05/1990 B.S., University of Michigan, Ann Arbor, MI |
08/1990 - 05/1992 M.S., University of Wisconsin, Madison, WI |
06/1992 - 05/1996 Ph.D., University of Wisconsin, Madison, WI. |
POSTGRADUATE TRAINING AND FELLOWSHIP APPOINTMENTS: |
09/1996 - 06/1999 Postdoctoral Trainee, Department of Medicine, Division of Physiology, University of California, San Diego, La Jolla, CA |
MILITARY SERVICE: |
N/A |
FACULTY APPOINTMENTS: |
07/1999 - 04/2001 Project Scientist, Department of Medicine, University of California, San Diego, La Jolla, CA |
04/2001 - 06/2011 Assistant Professor, Department of Physiology, Medical College of Wisconsin, Milwaukee, WI |
07/2011 - Present Associate Professor, Department of Physiology, Medical College of Wisconsin, Milwaukee, WI |
ADMINISTRATIVE APPOINTMENTS: |
2007 - 2010 Scientific Center Administrator, Human & Molecular Genetics Center |
2015 - 2017 Interim Scientific Administrator, Human & Molecular Genetics Center |
01/2016 - 06/2016 Interim Business Administrator, Human & Molecular Genetics Center |
07/2017 - Present Associate Director of Education and Academic Relations, Genomic Sciences and Precision Medicine Center, Medical College of Wisconsin |
EDUCATIONAL ADMINISTRATIVE APPOINTMENTS: |
01/2015 - Present Director of the Masters in Medical Physiology Program, Medical College of Wisconsin |
09/2017 - Present Vice Chair and Secretary, Curriculum and Evaluation Committee (Medical School), Medical College of Wisconsin |
RESEARCH ADMINISTRATIVE APPOINTMENTS: |
N/A |
AWARDS AND HONORS: |
1993 - 1996 Predoctoral Fellowship: National Heart, Lung and Blood Institute Grant HL 07654, University of Wisconsin, Madison, WI. |
1995 Veterinary Science Travel Award, University of Wisconsin, Madison, WI. |
1996 - 1999 Postdoctoral Fellowship: National Heart, Lung and Blood Institute Grant HL 07212 University of California, San Diego, La Jolla, CA. |
2000 - 2003 Parker B. Francis Fellowship (July 1, 2000- Jun 2003) |
2000 Frontiers in Modeling and Control of Breathing Trainee Award (Oxford Conference, Cape Cod, MA) |
2015 - 2016 Medical College of Wisconsin Leadership Academy, MCW and the University of Wisconsin-Milwaukee Sheldon B. Lubar School of Business |
2016 Outstanding Graduate School Teacher, Medical College of Wisconsin, 2015-2016 academic year. |
MEMBERSHIPS IN HONORARY AND PROFESSIONAL SOCIETIES: |
1991 - Present American Physiological Society |
1993 - 1995 International Chemoreceptor Society |
1994 - 2013 Society for Neuroscience |
2008 - 2015 International Society for Computational Biology |
2013 - Present American Heart Association |
EDITORSHIPS/EDITORIAL BOARDS/JOURNAL REVIEWS: |
Editorial Board |
2013 - 2015 Frontiers in Genomic Physiology |
2015 - Present Scientific Reports (Nature Publishing Group) |
Journal Review |
2005 Respiratory Physiology and Neurobiology |
2009 - Present Physiological Genomics |
2010 Mammalian Genome |
2010 Bioinformatics |
2010 - Present Briefings in Bioinformatics |
2011 - Present Database |
2013 Expert Opinion on Drug Discovery |
2013 - 2014 Nucleic Acids Research Database issue |
2013 F1000Prime Reports |
2014 - Present PlosOne |
2015 - Present Scientific Reports |
2017 - Present BMC Cardiovascular Disorders |
LOCAL/REGIONAL APPOINTED LEADERSHIP AND COMMITTEE POSITIONS: |
2002 - 2006 Oral presentation reviewer, Summer Program in Undergraduate Research, Medical College of Wisconsin |
2009 Community Engagement Committee, Human & Molecular Genetics Center, Medical College of Wisconsin |
2010 Member, Office of Research Innovations - Task Force on Mentoring, MCW |
2010 - 2015 Member, Food Service Committee, MCW |
03/2011 Committee member, Junior Faculty Committee - Basic Science, Liaison Committee on Medical Education (LCME) Site Visit, Medical College of Wisconsin |
2011 Panel member, "Strategies for Success in Science: A Balancing Act", Graduate Student Luncheon, Women's Faculty Council, Medical College of Wisconsin |
2011 Member, eBridge Focus Group, MCW Office of Research |
2011 - 2014 Member, Nomination Committee, MCW |
2011 - Present Member, Research Mentoring Committee, MCW |
2011 Reviewer, Skin Cancer Research Award, FMLH/MCW Skin Cancer Research Fund, Medical College of Wisconsin |
2012 - Present Poster reviewer, MCW Research Day, Medical College of Wisconsin |
2012 - 2016 Poster reviewer, Medical Student Research Day, Medical College of Wisconsin |
2012 - 2014 Admissions and Support Work Group Member, Community Medical Education Program Student Recruitment, MCW |
2013 Panel member, "How to Identify a Good Mentor", Graduate Student Luncheon, Women's Faculty Council, Medical College of Wisconsin |
2013 - 2014 Honors thesis reviewer, Medical Student Honors Thesis (M4 candidate), MCW |
2013 - Present member of IACUC Institutional Policies and Responsibilities subcommittee, IACUC Semi-Annual Program Review, MCW |
2013 - 2014 Grant reviewer, CTSI 2014 Pilot Award program, MCW |
2014 - 2017 Member, Women's Faculty Council, MCW |
2015 - 2016 Oral presentation reviewer, Summer Program in Undergraduate Research (SPUR), Medical College of Wisconsin |
2015 - 2016 Oral presentation reviewer, Diversity Summer Health-related Research (DSHREP), Medical College of Wisconsin |
2015 - 2016 Member, Search Committee for Department Chair for Microbiology & Molecular Genetics, MCW |
2015 - 2017 MCW, Graduate Studies Council Curriculum and Programs Committee, MCW Graduate School |
2016 - Present Search Committee for Center Director, Human & Molecular Genetics Center, member |
2016 Member, Search Committee for Chief Diversity and Inclusion Officer, MCW |
2016 - Present Member, Curriculum & Evaluation Committee: M1-M2 subcommittee, MCW Medical School |
2016 Honors thesis reviewer, Medical Student Honors Thesis (M4 Candidate), MCW |
2017 - Present Secretary/Vice Chair, Executive Curriculum & Evaluation Committee, MCW Medical School |
2018 - Present Chair, Curriculum & Program Committee, Graduate School, MCW Graduate School |
NATIONAL ELECTED/APPOINTED LEADERSHIP AND COMMITTEE POSITIONS: |
2003 - 2005 Member, Career Opportunities in Physiology, American Physiological Society |
2004 Grant Reviewer, EPSCoR Program, South Carolina Deepartment of Defense |
2006 - 2017 Ad hoc reviewer for Caroline tum Suden/Frances A Hellebrandt Opportunity Award, Women in Physiology, American Physiological Society |
2011 Grant Reviewer, Genomic Resources Grants for Community Resource Projects (PAR-11-095), NHGRI |
2012 Grant Reviewer, Biodata management and analysis (BDMA): study section, NIH |
2013 - 2017 Reviewer, Undergraduate Summer Research Fellowship awards, Career Opportunities in Physiology, American Physiological Society |
2013 Grant Reviewer, Lung 2 Spring Committee, American Heart Association |
2013 - 2015 Committee member, Women in Physiology, American Physiological Society |
2013 Grant Reviewer, Lung 2 Fall Committee, American Heart Association |
2014 - 2016 Co-chair, Lung 2 study section, American Heart Association |
2014 Grant Reviewer, Special Emphasis Panel/Scientific Review Group (2015/01 ZRG1 BBBP-Y (45) R), September 2014, NIH |
2014 - 2015 Reviewer, Bodil M. Schmidt-Nielson Award, Women in Physiology, American Physiological Society |
2015 Grant Reviewer, Special Emphasis Panel/Scientific Review Group (2015/10 ZRG1 BBBP-Y(45), September 2015, NIH |
2015 Grant Reviewer, Special Emphasis Panel/Scientific Review Group (ZRG1 BST-N(55)R), June 2015, NIH |
2015 Grant Reviewer, Special Emphasis Panel/Scientific Review Group (ZRG1 BST-A(40)), December 2015, NIH |
2015 Grant Reviewer, Special Emphasis Panel/Scientific Review Group (2015/10 ZRG1 BBBP-Y(45), May 2015, NIH |
2016 Grant Reviewer, Special Emphasis Panel/Scientific Review Group (ZRG1 BBBP-Y 45 R), January 2016, NIH |
2016 Grant Reviewer, NIH reviewer for Special Emphasis Panel/Scientific Review Group (2016/ZRG1 BST-K(30)I), S10 applications, November 2016, NIH |
2016 Grant Reviewer, NIH reviewer for Special Emphasis Panel/Scientific Review Group (2016/05 ZRG1 BST-U(55)), R24 applications, February 2016, NIH |
2016 Grant Reviewer, Lung 1 Fall Committee, American Heart Association |
2016 Grant Reviewer, Special Emphasis Panel/Scientific Review Group (2016/10 ZRG1 BBBP-Y(45)), R25 applications, May 2016, NIH |
2017 Grant Reviewer, Special Emphasis Panel/Scientific Review Group (2017/05 ZRG1 BST-J(55)), R25 applications for RFA-ES16-001: BD2K Research Education Curriculum Development, February 2017, NIH |
2017 Grant Reviewer, Cancer Center Basic Science Pilot Grant, MCW |
2017 Grant Reviewer, Special Emphasis Panel/Scientific Review Group (2017/05 ZRG1 BST-H(50)), U01 applications for RFA-LM-17-001: Enhancing the Efficiency and Effectiveness of Digital Curation for Biomedical Big Data, February 2017, NIH |
2018 - Present Member, External Advisory Board, NIDA Core Center of Excellence in Omics, Systems Genetics, and the Addictome (P30DA044223) |
2018 Temporary Member, Genetics of Health and Disease (GHD) Study Section, NIH |
RESEARCH GRANTS/AWARDS/CONTRACTS/PROJECTS: | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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INVITED LECTURES/WORKSHOPS/PRESENTATIONS: |
Local |
Dwinell, M.R., Neural plasticity of the peripheral chemoreflex, Department of Physiology, Medical College of Wisconsin, Milwaukee WI, 12/2000 |
Dwinell, M.R., Development of the control of breathing in piglets., Animal Resource Center Medical College of Wisconsin, Milwaukee WI, 02/12/2003 |
Dwinell, M.R., Ventilatory control in inbred strains of rats, Department of Physiology, Medical College of Wisconsin, Milwaukee WI, 03/05/2003 |
Dwinell, M.R., Consomic Rat Models for Respiratory Control, Department of Physiology, Medical College of Wisconsin, Milwaukee WI, 03/01/2006 |
Dwinell, M.R., Who's on first? Deciphering chromosome 1 using consomic rats, Department of Physiology, Medical College of Wisconsin, Milwaukee WI, 03/14/2007 |
Dwinell, M.R., Phenotypes and Disease Models: Lessons from the PGA., Department of Physiology, Medical College of Wisconsin, Milwaukee WI, 01/28/2009 |
Dwinell, M.R., Tools to identify animal models for complex disease., Human & Molecular Genetics Center, Medical College of Wisconsin, Milwaukee WI, 08/06/2009 |
Dwinell, M.R., New opportunities using rat models to study complex disease., Nephrology Research Conference, Dept. of Medicine, Medical College of Wisconsin, Milwaukee WI, 12/14/2010 |
Dwinell MR, Physiological Genomics using rat models, Pulmonary Fellow Orientation to Research, Medical College of Wisconsin, 02/11/2011 |
Dwinell, M.R., Making sense of Phenotypes: Developing an Integrated Web Portal for Phenotype Data., Human & Molecular Genetics Center, Medical College of Wisconsin, Milwaukee WI, 11/03/2011 |
Dwinell, M.R., Making sense of phenotypes: Integrating data for identifying disease models., Dept. of Physiology seminar series, Medical College of Wisconsin, Milwaukee WI, 10/17/2012 |
Dwinell, M.R., Rat models to study complex disease., Pulmonary Fellow Orientation to Research, Medical College of Wisconsin, Milwaukee WI, 02/07/2013 |
Dwinell, M.R., Identifying animal models for disease using molecular and physiological phenotypes., Cancer Cell Biology Research Forum, Cancer Center, Medical College of Wisconsin, Milwaukee WI, 03/28/2013 |
Dwinell, M.R., Creation and use of genetically modified animal models to study complex disease., Pulmonary Fellow Orientation to Research, Medical College of Wisconsin, Milwaukee WI, 02/07/2014 |
Dwinell, M.R., Pfister S, Sood R, Schmainda K., "Running a Lab", ADVANCE: From Postdoc to Faculty, Medical College of Wisconsin, Milwaukee WI, 11/02/2015 |
Dwinell, M.R., "Budgets", ADVANCE: From Postdoc to Faculty, Medical College of Wisconsin, Milwaukee WI, 01/06/2016 |
Dwinell, M.R., "Budgeting", ADVANCE: From Postdoc to Faculty, Medical College of Wisconsin, Milwaukee WI, 01/13/2017 |
Dwinell, M.R., "Demystifying the process: How a sample becomes genomic data", Conversations with Scientists, Advancing a Healthier Wisconsin 2018 Conversations with Scientists series, Milwaukee WI, 04/11/2018 |
Dwinell, M.R., Hybrid Mouse Rat Diversity Panel, Genomic Sciences & Precision Medicine Center, Medical College of Wisconsin, Milwaukee WI, 10/10/2018 |
Regional |
Dwinell, M.R., Hypoxic and hypercapnic ventilatory responses in inbred strains of rats, Kemp Station - Midwest Control of Breathing meeting, Minoqua, WI, 07/2002 |
National |
Dwinell, M.R, H. Kazemi, J. Lam and F.L Powell., Central amino acid neurotransmitters and ventilatory output and metabolism during acute hypoxia in anesthetized rats, Oxford Conference, Frontiers in Modeling and Control of Breathing, Cape Cod, MA, 2000 |
Dwinell, M.R., The Use of Designer Rat Models to Understand Heart, Lung, Blood and Kidney Disorders, American Association for Laboratory Animal Science (AALAS) National Meeting, Tampa Bay, FL, 10/21/2004 |
Dwinell, M.R. & Andrade F.H., International Collaborations: Science Knows No Boundaries., XXXV International Congress of Physiological Sciences, San Diego, CA, 04/03/2005 |
Dwinell, M.R. & H.J. Jacob., Building a phenome project: a physiological genomics approach to heart, lung, blood and sleep disorders in the rat., Tutorial Lecture at Morehouse School of Medicine workshop ("Genomic Applications in Heart, Lung, Blood and Sleep Disorders Research"), Atlanta, GA, 05/02/2005 |
Dwinell, M.R. & H.J. Jacob., Building a phenome project: a physiological genomics approach to heart, lung, blood and sleep disorders in the rat., Tutorial Lectures at From Genome to Disease II Symposium, Bethesda, MD, 07/19/2005 - 07/20/2005 |
Dwinell, M.R., Building a phenome project: a physiological genomics approach to heart, lung, blood and sleep disorders in the rat., Keynote presentation at 20th Anniversary RCMI Conference, Morgan State University, Baltimore, MD, 09/30/2005 |
Dwinell, M.R., Rat Genome Database Workshop: Phenotypes and Models Portal., Rat Genomics and Models meeting, Cold Spring Harbor, NY, 12/02/2005 - 12/05/2005 |
Dwinell, M.R., Rat Consomic Panels and ENU Mutagenesis. PGA Traveling Tutorial, Day 2 Quantitative Trait Genetics, Washington University, St. Louis, MO, 05/15/2006 - 05/16/2006 |
Dwinell, M.R., Target Organ Damage in Hypertension: Genetic and epigenetic susceptibilities., NHLBI Working Group, Bethesda, MD, 06/25/2008 |
Dwinell, M.R., Integration of phenotype data using multiple ontologies for disease model identification., Bullet presentation, 2012 Summit on Translational Bioinformatics, San Francisco, CA, 03/19/2012 - 03/20/2012 |
Dwinell, M.R., Bioinformatic network/pathway analyses - Finding where your favorite genes/proteins hangout., Workshop presentation, Experimental Biology, 2013, Boston, MA, 04/20/2013 |
Dwinell, M.R., Animal Models of Lung Disease: Rat genomics and bioinformatics to understand disease., NHLBI working group, Bethesda, MD, 09/26/2013 |
Dwinell, M.R. and Shimoyama, M., Toxicogenomics Data at the Rat Genome Database. Raleigh, NIEHS Keystone Lecture, Raleigh, NC, 03/17/2014 |
Dwinell, M.R., Chromosome-dependent regulation of cardiovascular function, NHLBI Sex Bias in Cardiovascular Research Working Group, Bethesda, MD, 09/22/2014 |
Dwinell, M.R., Genomic and Phenotypic Rat Strain Profiles for Disease Model Identification. Physiological Genomics Workshop presentation, Experimental Biology 2015, Boston MA, 03/28/2015 |
Dwinell, M.R., Unraveling disease through rat models using innovation and informatics., School of Pharmacy University of Colorado Anschutz Medical Campus, Denver, CO, 10/07/2015 |
Dwinell, M.R., Unraveling disease through rat models using innovation and informatics. Institute for Behavioral Genetics, University of Colorado Boulder, Boulder CO, 10/08/2015 |
Dwinell, M.R., Rat Strain Profiles: the good, the bad, and the ugly., Rat Genomics and Models meeting, Cold Spring Harbor Laboratory, NY, 12/11/2015 |
Saba, L, Dwinell, M.R., Tabakoff B., National Rat Genetic Resource Program., NIH ORIP, Bethesda, MD, 12/14/2015 |
Dwinell, M.R., Unraveling disease through rat models using innovation and informatics, Ferris State University, Big Rapids, MI, 03/18/2016 |
Dwinell, M.R., Women in Physiology Strategic Planning Meeting, American Physiological Society, Bethesda, MD, 05/02/2016 - 05/03/2016 |
Dwinell, M.R., Development of tagged CMA1 overexpression in SD rat model., Wake Forest University, Winston-Salem, NC, 10/05/2017 |
Dwinell, M.R., The Rat Genome Database and the Variant Visualizer., University of Colorado, Skaggs School of Pharmacy and Pharmaceutical Sciences, Denver, CO, 07/23/2018 |
International |
Dwinell, M.R., Janssen PL, Pizzaro J, Bisgard GE., Increased carotid body CO2 sensitivity after ventilatory acclimatization to hypoxia in awake goats, International Chemoreceptor Society, Santiago, Chile, 1999 |
Dwinell MR, Phenotypes and Models Portal at RGD: Providing an entrée to genomics for physiologists., Cold Spring Harbor Rat Genomics and Models Meeting, Wellcome Trust Center, Hinxton UK, 12/2008 |
PEER REVIEWED WORKSHOPS/PRESENTATIONS: |
Regional |
Dwinell, M.R., Couples that Work in Medicine and/or Science - How do you make it work?, The Medical Scientist Training Program Annual Retreat, Panel Presentation, Sheboygan WI, 11/14/2008 |
National |
Dwinell, M.R., The Use of Designer Rat Models to Understand Heart, Lung, Blood and Kidney Disorders., Special Topic Lecture at the American Association for Laboratory Animal Science (AALAS) National Meeting, Tampa Bay, FL, 10/21/2004 |
Dwinell, M.R., Building a phenome project: a physiological genomics approach to heart, lung, blood and sleep disorders in the rat., Keynote presentation at 20th Anniversary RCMI Conference, Morgan State University, Baltimore, MD, 09/30/2005 |
Dwinell, M.R., Mentoring for Diverse Careers: Mentor and Protégé Perspectives., Experimental Biology 2015, Symposium hosted by APS Women in Physiology, Boston MA, 04/01/2015 |
COMMITTEE SERVICE: |
Medical College |
07/01/2005 - 06/30/2008 Department of Physiology representative, Faculty Council, Medical College of Wisconsin |
2010 committee member, Task Force on Mentoring, Office of Research, Medical College of Wisconsin |
2010 - 2015 Committee member, Food Service Committee, Medical College of Wisconsin |
2011 Committee member, Faculty Council Nominating Commitee, Medical College of Wisconsin |
2011 - Present Committee Member, Research Mentoring Commitee, Office of Research, Medical College of Wisconsin |
2012 - 2015 Committee member, Community Medical Education Program: Student Recruitment, Admissions and Support Work Group, Medical College of Wisconsin |
07/01/2014 - 06/30/2017 Committee Member, Council for Women's Advocacy (formerly Women's Faculty Council), Medical College of Wisconsin |
2015 - 2016 Committee Member, Search committee for Chair of Microbiology & Molecular Genetics, Medical College of Wisconsin |
2015 - Present Committee Member, Curriculum and Programs Committee, Graduate School, Medical College of Wisconsin |
2016 - Present Committee Member, Curriculum and Evaluation Committee, M1-M2 subcommittee, Medical College of Wisconsin |
2016 Committee Member, Search Committee for Director of Human & Molecular Genetics Center, Medical College of Wisconsin |
2016 Committee Member, Search Committee for Chief Diversity and Inclusion Officer, Medical College of Wisconsin |
2017 - Present Committee Member, Biomedical Resource Center Advisory Committee, Medical College of Wisconsin |
2017 - Present Vice Chair/Secretary, Executive Committee of the Curriculum and Evaluation Committee, Medical College of Wisconsin |
2018 - Present Chair, Curriculum & Program Committee, Graduate School, Medical College of Wisconsin |
2018 - Present Taskforce member, M1-M2 Grading Taskforce, Curriculum & Evaluation Committee, Medical College of Wisconsin |
MEDICAL COLLEGE TEACHING ACTIVITIES: |
Medical Student Education |
2005 - 2011 Medical Physiology - Pulmonary Physiology lab |
2005 - 2006 Medical Physiology - Cardiovascular lab |
2012 - 2014 Mentor for Neehar Raj, Physician Scientist Pathway |
08/15/2018 - Present M1 Physiology Course, Co-Director (shadowing Dr. Julian Lombard, Course Director) |
Resident and Fellow Education |
2011 Pulmonary Fellow Research Elective - Introduction to Physiological Genomics and Sequencing Technologies |
2012 Pulmonary Fellow Research Elective - Creating and use of genetically modified animals |
Graduate Student Education |
2011 - Present Physiological Genomics, Bioinformatics lectures and hands-on laboratories |
2016 - Present Physiological Genomics - MMP student essay and oral presentations |
2016 - Present Physiological Genomics - Comparative Genomics, Linkage Mapping, and Genome Sequence lectures |
EXTRAMURAL TEACHING: |
Community/Lay Public |
11/2005 - 12/2005 University of Wisconsin- Milwaukee, Pulmonary Pathophysiology lectures for nursing students |
11/2005 Pilgrim Park Middle School, Brookfield WI, PhUn day (Physiology Understanding) |
11/2015 Brookfield East High School, Brookfield WI, Tour and hands-on lab in the Human & Molecular Genetics Center at the Medical College of Wisconsin |
03/2017 Brookfield East High School, Brookfield WI, A Day in the Life of a Physiologist |
MCW STUDENTS, FACULTY, RESIDENTS AND CLINICAL/RESEARCH FELLOWS MENTORED: |
Undergraduate Students |
Nathan Miller, Medical College of Wisconsin, 06/2002 - 08/2002 Preceptor, Summer Program for Undergraduate Research, Oral presentation |
Eddie Sirlin, Medical College of Wisconsin, 06/2003 - 08/2003 Preceptor, Summer Program for Undergraduate Research, Oral presentation |
Michelle Beulow, Medical College of Wisconsin, 06/2004 - 08/2004 Preceptor, Summer Program for Undergraduate Research, Oral presentation |
Sophia Venero, Medical College of Wisconsin, 06/2014 - 08/2014 Preceptor, DSHREP summer research program, Oral presentation |
Asia Henderson, Medical College of Wisconsin, 06/2015 - 08/2015 Preceptor, DSHREP summer research program, Oral presentation |
Sara Imam, Medical College of Wisconsin, 06/2016 - 08/2016 Preceptor, DSHREP summer research program, Oral presentation |
Asha Woodfolk, Medical College of Wisconsin, 06/2017 - 08/2017 Preceptor, DSHREP summer research program, Oral presentation |
Miracle Powell, Medical College of Wisconsin, 06/2018 - 08/2018 Preceptor, DSHREP summer research program, Oral presentation |
Medical Students |
Neehar Raj, Medical College of Wisconsin, 03/2012 - 06/2014 Pathyway mentor, Poster presentation at Medical Student poster session |
Graduate Students |
MS Committees |
Genevieve E. Hogan, Medical College of Wisconsin, 07/2001 - 08/2003, Master of Science degree, Physiology graduate student |
PhD Students Advised |
G. Mouradian, Jr., Medical College of Wisconsin, 08/2009 - 10/2009, Rotation project completion, Physiology graduate student |
Nan Cher Yeo, Medical College of Wisconsin, 08/2010 - 09/2010, Rotation project completion, Physiology graduate student |
Students Advised |
Madeline Jewell, Medical College of Wisconsin, 08/2017 - 12/2017, Rotation project completion, Physiology graduate student |
Committees |
Maribel Marquez, Medical College of Wisconsin, 01/2018 - Present, Ongoing mentoring, Physiology graduate student |
Alicia Ivory, Medical College of Wisconsin, 02/2018 - Present, Ongoing, Physiology graduate student |
PROGRAMMATIC DEVELOPMENTS: |
Educational Programs |
Faculty |
2014 - 2015 Developed Masters in Medical Physiology Program, approved through Graduate School on March 2, 2015 |
2015 - Present Director of Masters in Medical Physiology Program, MCW Graduate School |
COMMUNITY SERVICE ACTIVITIES: |
2011 Milwaukee Public Schools Science Fair - reviewer |
2017 EgGS Initiative (Engaging Girls in Stem) workshop participant, Medical College of Wisconsin |
2018 MCW Cancer Crush, "Bella is wagging her tail to crush cancer"
(https://www.youtube.com/watch?v=otUPZSFSwkU&feature=youtu.be), July 2018 |
BIBLIOGRAPHY |
Refereed Journal Publications/Original Papers |
1. Ryan ML, Hedrick MS, Pizarro J, Bisgard GE. Effects of carotid body sympathetic denervation on ventilatory acclimatization to hypoxia in the goat. Respir Physiol. 1995 Feb;99(2):215-24. |
2. Pizarro J, Ryan ML, Hedrick MS, Xue DH, Keith IM, Bisgard GE. Intracarotid substance P infusion inhibits ventilation in the goat. Respir Physiol. 1995 Jul;101(1):11-22. |
3. Ryan ML, Hedrick MS, Pizarro J, Bisgard GE. Carotid body noradrenergic sensitivity in ventilatory acclimatization to hypoxia. Respir Physiol. 1993 Apr;92(1):77-90. |
4. Forster HV, Dwinell MR, Hodges MR, Brozoski D, Hogan GE. Do genes on rat chromosomes 9, 13, 16, 18, and 20 contribute to regulation of breathing? Respir Physiol Neurobiol. 2003 May 30;135(2-3):247-61. |
5. Kwitek AE, Jacob HJ, Baker JE, Dwinell MR, Forster HV, Greene AS, Kunert MP, Lombard JH, Mattson DL, Pritchard KA Jr, Roman RJ, Tonellato PJ, Cowley AW Jr. BN phenome: detailed characterization of the cardiovascular, renal, and pulmonary systems of the sequenced rat. Physiol Genomics. 2006 Apr 13;25(2):303-13. |
6. Hedrick MS, Ryan ML, Pizarro J, Bisgard GE. Modulation of respiratory rhythm by alpha 2-adrenoceptors in awake and anesthetized goats. J Appl Physiol (1985). 1994 Aug;77(2):742-50. |
7. Hedrick MS, Ryan ML, Bisgard GE. Recurrent laryngeal nerve activation by alpha 2 adrenergic agonists in goats. Respir Physiol. 1995 Aug;101(2):129-37. |
8. Hodges MR, Forster HV, Papanek PE, Dwinell MR, Hogan GE. Ventilatory phenotypes among four strains of adult rats. J Appl Physiol (1985). 2002 Sep;93(3):974-83. |
9. Dwinell MR, Forster HV, Petersen J, Rider A, Kunert MP, Cowley AW Jr, Jacob HJ. Genetic determinants on rat chromosome 6 modulate variation in the hypercapnic ventilatory response using consomic strains. J Appl Physiol (1985). 2005 May;98(5):1630-8. |
10. Kunert MP, Drenjancevic-Peric I, Dwinell MR, Lombard JH, Cowley AW Jr, Greene AS, Kwitek AE, Jacob HJ. Consomic strategies to localize genomic regions related to vascular reactivity in the Dahl salt-sensitive rat. Physiol Genomics. 2006 Aug 16;26(3):218-25. |
11. Mattson DL, Dwinell MR, Greene AS, Kwitek AE, Roman RJ, Cowley AW Jr, Jacob HJ. Chromosomal mapping of the genetic basis of hypertension and renal disease in FHH rats. Am J Physiol Renal Physiol. 2007 Dec;293(6):F1905-14. |
12. Dwinell MR. Physiological genomics: from bench to bedside. Exp Physiol. 2007 Nov;92(6):987. |
13. Dwinell MR, Kazemi H, Lam JT, Powell FL. Central amino acid neurotransmitters, ventilatory output and metabolism during acute hypoxia in anesthetized rats. Adv Exp Med Biol. 2001;499:291-6. |
14. Olson EB Jr, Bohne CJ, Dwinell MR, Podolsky A, Vidruk EH, Fuller DD, Powell FL, Mitchel GS. Ventilatory long-term facilitation in unanesthetized rats. J Appl Physiol (1985). 2001 Aug;91(2):709-16. |
15. Powell FL, Dwinell MR, Aaron EA. Measuring ventilatory acclimatization to hypoxia: comparative aspects. Respir Physiol. 2000 Sep;122(2-3):271-84. |
16. Powell FL, Huey KA, Dwinell MR. Central nervous system mechanisms of ventilatory acclimatization to hypoxia. Respir Physiol. 2000 Jul;121(2-3):223-36. |
17. Dwinell MR, Huey KA, Powell FL. Chronic hypoxia induces changes in the central nervous system processing of arterial chemoreceptor input. Adv Exp Med Biol. 2000;475:477-84. |
18. Dwinell MR, Powell FL. Chronic hypoxia enhances the phrenic nerve response to arterial chemoreceptor stimulation in anesthetized rats. J Appl Physiol (1985). 1999 Aug;87(2):817-23. |
19. Hedrick MS, Dwinell MR, Janssen PL, Pizarro J, Bisgard GE. Differential respiratory muscle recruitment induced by clonidine in awake goats. J Appl Physiol (1985). 1998 Apr;84(4):1198-207. |
20. Janssen PL, Dwinell MR, Pizarro J, Bisgard GE. Intracarotid dopamine infusion does not prevent acclimatization to hypoxia. Respir Physiol. 1998 Jan;111(1):33-43. |
21. Janssen PL, O'Halloran KD, Pizarro J, Dwinell MR, Bisgard GE. Carotid body dopaminergic mechanisms are functional after acclimatization to hypoxia in goats. Respir Physiol. 1998 Jan;111(1):25-32. |
22. Dwinell MR, Janssen PL, Bisgard GE. Lack of long-term facilitation of ventilation after exposure to hypoxia in goats. Respir Physiol. 1997 Apr;108(1):1-9. |
23. Dwinell MR, Janssen PL, Pizarro J, Bisgard GE. Effects of carotid body hypocapnia during ventilatory acclimatization to hypoxia. J Appl Physiol (1985). 1997 Jan;82(1):118-24. |
24. Dwinell MR, Janssen PL, Pizarro J, Bisgard GE. The role of carotid body CO2 during ventilatory acclimatization to hypoxia in the goat. Adv Exp Med Biol. 1996;410:387-90. |
25. Janssen PL, Dwinell MR, Pizarro DJ, Bisgard GE. Effects of continuous intracarotid infusion of dopamine during long-term hypoxia in awake goats. Adv Exp Med Biol. 1996;410:383-6. |
26. Xue D, Keith IM, Dwinell MR, Bisgard GE. Mitochondrial division, blood vessel dilation, and large intercellular space expansion of goat carotid body during hypoxia. Adv Exp Med Biol. 1996;410:55-8. |
27. Dwinell MR, Worthey EA, Shimoyama M, Bakir-Gungor B, DePons J, Laulederkind S, Lowry T, Nigram R, Petri V, Smith J, Stoddard A, Twigger SN, Jacob HJ, RGD Team. The Rat Genome Database 2009: variation, ontologies and pathways. Nucleic Acids Res. 2009 Jan;37(Database issue):D744-9. PMCID: PMC2686558 |
28. Laulederkind SJ, Shimoyama M, Hayman GT, Lowry TF, Nigam R, Petri V, Smith JR, Wang SJ, de Pons J, Kowalski G, Liu W, Rood W, Munzenmaier DH, Dwinell MR, Twigger SN, Jacob HJ, RGD Team. The Rat Genome Database curation tool suite: a set of optimized software tools enabling efficient acquisition, organization, and presentation of biological data. Database (Oxford). 2011;2011:bar002. PMCID: PMC3041158 |
29. Mattson DL, Dwinell MR, Greene AS, Kwitek AE, Roman RJ, Jacob HJ, Cowley AW Jr. Chromosome substitution reveals the genetic basis of Dahl salt-sensitive hypertension and renal disease. Am J Physiol Renal Physiol. 2008 Sep;295(3):F837-42. PMCID: PMC2536867 |
30. Gene Ontology Consortium. The Gene Ontology: enhancements for 2011. Nucleic Acids Res. 2012 Jan;40(Database issue):D559-64. PMCID: PMC3245151 |
31. Petri V, Shimoyama M, Hayman GT, Smith JR, Tutaj M, de Pons J, Dwinell MR, Munzenmaier DH, Twigger SN, Jacob HJ, RGD Team. The Rat Genome Database pathway portal. Database (Oxford). 2011;2011:bar010. PMCID: PMC3072770 |
32. Dwinell MR. Online tools for understanding rat physiology. Brief Bioinform. 2010 Jul;11(4):431-9. PMCID: PMC2905522 |
33. Riley D, Dwinell M, Qian B, Krause KL, Bonis JM, Neumueller S, Marshall BD, Hodges MR, Forster HV. Differences between three inbred rat strains in number of K+ channel-immunoreactive neurons in the medullary raphé nucleus. J Appl Physiol (1985). 2010 Apr;108(4):1003-10. PMCID: PMC2853200 |
34. Shimoyama M, Hayman GT, Laulederkind SJ, Nigam R, Lowry TF, Petri V, Smith JR, Wang SJ, Munzenmaier DH, Dwinell MR, Twigger SN, Jacob HJ, RGD Team. The rat genome database curators: who, what, where, why. PLoS Comput Biol. 2009 Nov;5(11):e1000582. PMCID: PMC2775909 |
35. Jacob HJ, Lazar J, Dwinell MR, Moreno C, Geurts AM. Gene targeting in the rat: advances and opportunities. Trends Genet. 2010 Dec;26(12):510-8. PMCID: PMC2991520 |
36. Dwinell MR, Lazar J, Geurts AM. The emerging role for rat models in gene discovery. Mamm Genome. 2011 Aug;22(7-8):466-75. PMCID: PMC3643810 |
37. Dwinell MR, Hogan GE, Sirlin E, Mayhew DL, Forster HV. Postnatal ventilatory response to CO₂ in awake piglets. Respir Physiol Neurobiol. 2011 Jan 31;175(1):49-54. |
38. Kunert MP, Dwinell MR, Lombard JH. Vascular responses in aortic rings of a consomic rat panel derived from the Fawn Hooded Hypertensive strain. Physiol Genomics. 2010 Nov 29;42A(4):244-58. PMCID: PMC3008365 |
39. Kunert MP, Dwinell MR, Drenjancevic Peric I, Lombard JH. Sex-specific differences in chromosome-dependent regulation of vascular reactivity in female consomic rat strains from a SSxBN cross. Am J Physiol Regul Integr Comp Physiol. 2008 Aug;295(2):R516-27. PMCID: PMC2519925 |
40. Laulederkind SJ, Tutaj M, Shimoyama M, Hayman GT, Lowry TF, Nigam R, Petri V, Smith JR, Wang SJ, de Pons J, Dwinell MR, Jacob HJ. Ontology searching and browsing at the Rat Genome Database. Database (Oxford). 2012;2012:bas016. PMCID: PMC3308169 |
41. Shimoyama M, Nigam R, McIntosh LS, Nagarajan R, Rice T, Rao DC, Dwinell MR. Three ontologies to define phenotype measurement data. Front Genet. 2012;3:87. PMCID: PMC3361058 |
42. Basile DP, Dwinell MR, Wang SJ, Shames BD, Donohoe DL, Chen S, Sreedharan R, Van Why SK. Chromosome substitution modulates resistance to ischemia reperfusion injury in Brown Norway rats. Kidney Int. 2013 Feb;83(2):242-50. PMCID: PMC3561482 |
43. Laulederkind SJ, Hayman GT, Wang SJ, Lowry TF, Nigam R, Petri V, Smith JR, Dwinell MR, Jacob HJ, Shimoyama M. Exploring genetic, genomic, and phenotypic data at the rat genome database. Curr Protoc Bioinformatics. 2012 Dec;Chapter 1:Unit1.14. PMCID: PMC3555435 |
44. Hayman GT, Jayaraman P, Petri V, Tutaj M, Liu W, De Pons J, Dwinell MR, Shimoyama M. The updated RGD Pathway Portal utilizes increased curation efficiency and provides expanded pathway information. Hum Genomics. 2013 Feb 05;7:4. PMCID: PMC3598722 |
45. Gene Ontology Consortium, Blake JA, Dolan M, Drabkin H, Hill DP, Li N, Sitnikov D, Bridges S, Burgess S, Buza T, McCarthy F, Peddinti D, Pillai L, Carbon S, Dietze H, Ireland A, Lewis SE, Mungall CJ, Gaudet P, Chrisholm RL, Fey P, Kibbe WA, Basu S, Siegele DA, McIntosh BK, Renfro DP, Zweifel AE, Hu JC, Brown NH, Tweedie S, Alam-Faruque Y, Apweiler R, Auchinchloss A, Axelsen K, Bely B, Blatter M-, Bonilla C, Bouguerleret L, Boutet E, Breuza L, Bridge A, Chan WM, Chavali G, Coudert E, Dimmer E, Estreicher A, Famiglietti L, Feuermann M, Gos A, Gruaz-Gumowski N, Hieta R, Hinz C, Hulo C, Huntley R, James J, Jungo F, Keller G, Laiho K, Legge D, Lemercier P, Lieberherr D, Magrane M, Martin MJ, Masson P, Mutowo-Muellenet P, O'Donovan C, Pedruzzi I, Pichler K, Poggioli D, Porras Millán P, Poux S, Rivoire C, Roechert B, Sawford T, Schneider M, Stutz A, Sundaram S, Tognolli M, Xenarios I, Foulgar R, Lomax J, Roncaglia P, Khodiyar VK, Lovering RC, Talmud PJ, Chibucos M, Giglio MG, Chang H-, Hunter S, McAnulla C, Mitchell A, Sangrador A, Stephan R, Harris MA, Oliver SG, Rutherford K, Wood V, Bahler J, Lock A, Kersey PJ, McDowall DM, Staines DM, Dwinell M, Shimoyama M, Laulederkind S, Hayman T, Wang S-, Petri V, Lowry T, D'Eustachio P, Matthews L, Balakrishnan R, Binkley G, Cherry JM, Costanzo MC, Dwight SS, Engel SR, Fisk DG, Hitz BC, Hong EL, Karra K, Miyasato SR, Nash RS, Park J, Skrzypek MS, Weng S, Wong ED, Berardini TZ, Huala E, Mi H, Thomas PD, Chan J, Kishore R, Sternberg P, Van Auken K, Howe D, Westerfield M. Gene Ontology annotations and resources. Nucleic Acids Res. 2013 Jan;41(Database issue):D530-5. PMCID: PMC3531070 |
46. Laulederkind SJ, Hayman GT, Wang SJ, Smith JR, Lowry TF, Nigam R, Petri V, de Pons J, Dwinell MR, Shimoyama M, Munzenmaier DH, Worthey EA, Jacob HJ. The Rat Genome Database 2013--data, tools and users. Brief Bioinform. 2013 Jul;14(4):520-6. PMCID: PMC3713714 |
47. Allen KP, Dwinell MR, Zappa A, Temple A, Thulin J. Comparison of 2 rat breeding schemes using conventional caging. J Am Assoc Lab Anim Sci. 2013 Mar;52(2):142-5. PMCID: PMC3624781 |
48. Laulederkind SJ, Liu W, Smith JR, Hayman GT, Wang SJ, Nigam R, Petri V, Lowry TF, de Pons J, Dwinell MR, Shimoyama M. PhenoMiner: quantitative phenotype curation at the rat genome database. Database (Oxford). 2013;2013:bat015. PMCID: PMC3630803 |
49. Wang SJ, Laulederkind SJ, Hayman GT, Smith JR, Petri V, Lowry TF, Nigam R, Dwinell MR, Worthey EA, Munzenmaier DH, Shimoyama M, Jacob HJ. Analysis of disease-associated objects at the Rat Genome Database. Database (Oxford). 2013;2013:bat046. PMCID: PMC3689439 |
50. Nigam R, Laulederkind SJ, Hayman GT, Smith JR, Wang SJ, Lowry TF, Petri V, De Pons J, Tutaj M, Liu W, Jayaraman P, Munzenmaier DH, Worthey EA, Dwinell MR, Shimoyama M, Jacob HJ. Rat Genome Database: a unique resource for rat, human, and mouse quantitative trait locus data. Physiol Genomics. 2013 Sep 16;45(18):809-16. PMCID: PMC3783816 |
51. Flister MJ, Tsaih SW, O'Meara CC, Endres B, Hoffman MJ, Geurts AM, Dwinell MR, Lazar J, Jacob HJ, Moreno C. Identifying multiple causative genes at a single GWAS locus. Genome Res. 2013 Dec;23(12):1996-2002. PMCID: PMC3847770 |
52. Li Z, Ward BD, Dwinell MR, Lombard JH, Pawela CP. FMRI and fcMRI phenotypes map the genomic effect of chromosome 13 in Brown Norway and Dahl salt-sensitive rats. Neuroimage. 2014 Apr 15;90:403-12. |
53. Smith JR, Park CA, Nigam R, Laulederkind SJ, Hayman GT, Wang SJ, Lowry TF, Petri V, Pons JD, Tutaj M, Liu W, Worthey EA, Shimoyama M, Dwinell MR. The clinical measurement, measurement method and experimental condition ontologies: expansion, improvements and new applications. J Biomed Semantics. 2013 Oct 08;4(1):26. PMCID: PMC3882879 |
54. Nigam R, Munzenmaier DH, Worthey EA, Dwinell MR, Shimoyama M, Jacob HJ. Rat Strain Ontology: structured controlled vocabulary designed to facilitate access to strain data at RGD. J Biomed Semantics. 2013 Nov 22;4(1):36. PMCID: PMC4177145 |
55. Beyer AM, Raffai G, Weinberg BD, Fredrich K, Rodgers MS, Geurts AM, Jacob HJ, Dwinell MR, Lombard JH. Amelioration of salt-induced vascular dysfunction in mesenteric arteries of Dahl salt-sensitive rats by missense mutation of extracellular superoxide dismutase. Am J Physiol Heart Circ Physiol. 2014 Feb;306(3):H339-47. PMCID: PMC3920146 |
56. Petri V, Jayaraman P, Tutaj M, Hayman GT, Smith JR, De Pons J, Laulederkind SJ, Lowry TF, Nigam R, Wang SJ, Shimoyama M, Dwinell MR, Munzenmaier DH, Worthey EA, Jacob HJ. The pathway ontology - updates and applications. J Biomed Semantics. 2014 Feb 05;5(1):7. PMCID: PMC3922094 |
57. Petri V, Hayman GT, Tutaj M, Smith JR, Laulederkind SJ, Wang SJ, Nigam R, De Pons J, Shimoyama M, Dwinell MR, Worthey EA, Jacob HJ. Disease pathways at the Rat Genome Database Pathway Portal: genes in context-a network approach to understanding the molecular mechanisms of disease. Hum Genomics. 2014 Sep 30;8:17. PMCID: PMC4191248 |
58. Shimoyama M, De Pons J, Hayman GT, Laulederkind SJ, Liu W, Nigam R, Petri V, Smith JR, Tutaj M, Wang SJ, Worthey E, Dwinell M, Jacob H. The Rat Genome Database 2015: genomic, phenotypic and environmental variations and disease. Nucleic Acids Res. 2015 Jan;43(Database issue):D743-50. PMCID: PMC4383884 |
59. Li C, Li Z, Ward BD, Dwinell MR, Lombard JH, Hudetz AG, Pawela CP. Enhancement of resting-state fcMRI networks by prior sensory stimulation. Brain Connect. 2014 Nov;4(9):760-8. PMCID: PMC4238242 |
60. Liu W, Laulederkind SJ, Hayman GT, Wang SJ, Nigam R, Smith JR, De Pons J, Dwinell MR, Shimoyama M. OntoMate: a text-mining tool aiding curation at the Rat Genome Database. Database (Oxford). 2015;2015. PMCID: PMC4305386 |
61. Wang SJ, Laulederkind SJ, Hayman GT, Petri V, Liu W, Smith JR, Nigam R, Dwinell MR, Shimoyama M. PhenoMiner: a quantitative phenotype database for the laboratory rat, Rattus norvegicus. Application in hypertension and renal disease. Database (Oxford). 2015;2015. PMCID: PMC4309021 |
62. Gene Ontology Consortium. Gene Ontology Consortium: going forward. Nucleic Acids Res. 2015 Jan;43(Database issue):D1049-56. PMCID: PMC4383973 |
63. Flister MJ, Prokop JW, Lazar J, Shimoyama M, Dwinell M, Geurts A, International Committee on Standardized Genetic Nomenclature for Mice, Rat Genome and Nomenclature Committee. 2015 Guidelines for Establishing Genetically Modified Rat Models for Cardiovascular Research. J Cardiovasc Transl Res. 2015 Jun;8(4):269-77. PMCID: PMC4475456 |
64. Nayak S, Khan MA, Wan TC, Pei H, Linden J, Dwinell MR, Geurts AM, Imig JD, Auchampach JA. Characterization of Dahl salt-sensitive rats with genetic disruption of the A2B adenosine receptor gene: implications for A2B adenosine receptor signaling during hypertension. Purinergic Signal. 2015 Dec;11(4):519-31. PMCID: PMC4648794 |
65. Allen KP, Dwinell MR, Zappa AM, Michaels AM, Murray KM, Thulin JD. Rat Breeding Parameters According to Floor Space Available in Cage. J Am Assoc Lab Anim Sci. 2016 Jan;55(1):21-4. PMCID: PMC4747006 |
66. Prokop JW, Tsaih SW, Faber AB, Boehme S, Underwood AC, Troyer S, Playl L, Milsted A, Turner ME, Ely D, Martins AS, Tutaj M, Lazar J, Dwinell MR, Jacob HJ. The phenotypic impact of the male-specific region of chromosome-Y in inbred mating: the role of genetic variants and gene duplications in multiple inbred rat strains. Biol Sex Differ. 2016;7:10. PMCID: PMC4740989 |
67. Rubattu S, Di Castro S, Schulz H, Geurts AM, Cotugno M, Bianchi F, Maatz H, Hummel O, Falak S, Stanzione R, Marchitti S, Scarpino S, Giusti B, Kura A, Gensini GF, Peyvandi F, Mannucci PM, Rasura M, Sciarretta S, Dwinell MR, Hubner N, Volpe M. Ndufc2 Gene Inhibition Is Associated With Mitochondrial Dysfunction and Increased Stroke Susceptibility in an Animal Model of Complex Human Disease. J Am Heart Assoc. 2016 Feb 17;5(2). PMCID: PMC4802485 |
68. Hayman GT, Laulederkind SJ, Smith JR, Wang SJ, Petri V, Nigam R, Tutaj M, De Pons J, Dwinell MR, Shimoyama M. The Disease Portals, disease-gene annotation and the RGD disease ontology at the Rat Genome Database. Database (Oxford). 2016;2016. PMCID: PMC4805243 |
69. Wang SJ, Laulederkind SJ, Hayman GT, Petri V, Smith JR, Tutaj M, Nigam R, Dwinell MR, Shimoyama M. Comprehensive coverage of cardiovascular disease data in the disease portals at the Rat Genome Database. Physiol Genomics. 2016 08 01;48(8):589-600. PMCID: PMC5005459 |
70. Maric-Bilkan C, Arnold AP, Taylor DA, Dwinell M, Howlett SE, Wenger N, Reckelhoff JF, Sandberg K, Churchill G, Levin E, Lundberg MS. Report of the National Heart, Lung, and Blood Institute Working Group on Sex Differences Research in Cardiovascular Disease: Scientific Questions and Challenges. Hypertension. 2016 May;67(5):802-7. PMCID: PMC4833564 |
71. Petri V, Hayman GT, Tutaj M, Smith JR, Laulederkind S, Wang SJ, Nigam R, De Pons J, Shimoyama M, Dwinell MR. Disease, Models, Variants and Altered Pathways-Journeying RGD Through the Magnifying Glass. Comput Struct Biotechnol J. 2016;14:35-48. PMCID: PMC4700298 |
72. Shimoyama M, Laulederkind SJ, De Pons J, Nigam R, Smith JR, Tutaj M, Petri V, Hayman GT, Wang SJ, Ghiasvand O, Thota J, Dwinell MR. Exploring human disease using the Rat Genome Database. Dis Model Mech. 2016 10 01;9(10):1089-1095. PMCID: PMC5087824 |
73. Densmore JC, Schaid TR, Jeziorczak PM, Medhora M, Audi S, Nayak S, Auchampach J, Dwinell MR, Geurts AM, Jacobs ER. Lung injury pathways: Adenosine receptor 2B signaling limits development of ischemic bronchiolitis obliterans organizing pneumonia. Exp Lung Res. 2017 02;43(1):38-48. PMCID: PMC5831175 |
74. Flister MJ, Tsaih SW, Stoddard A, Plasterer C, Jagtap J, Parchur AK, Sharma G, Prisco AR, Lemke A, Murphy D, Al-Gizawiy M, Straza M, Ran S, Geurts AM, Dwinell MR, Greene AS, Bergom C, LaViolette PS, Joshi A. Host genetic modifiers of nonproductive angiogenesis inhibit breast cancer. Breast Cancer Res Treat. 2017 Aug;165(1):53-64. |
75. Hirabayashi M, Hara H, Goto T, Takizawa A, Dwinell MR, Yamanaka T, Hochi S, Nakauchi H. Haploid embryonic stem cell lines derived from androgenetic and parthenogenetic rat blastocysts. J Reprod Dev. 2017 Dec 15;63(6):611-616. PMCID: PMC5735273 |
76. Shimoyama M, Smith JR, Bryda E, Kuramoto T, Saba L, Dwinell M. Rat Genome and Model Resources. ILAR J. 2017 07 01;58(1):42-58. PMCID: PMC6057551 |
77. Laulederkind SJF, Hayman GT, Wang SJ, Smith JR, Petri V, Hoffman MJ, De Pons J, Tutaj MA, Ghiasvand O, Tutaj M, Thota J, Dwinell MR, Shimoyama M. A Primer for the Rat Genome Database (RGD). Methods Mol Biol. 2018;1757:163-209. |
78. Siebers EM, Choi MJ, Tinklenberg JA, Beatka MJ, Ayres S, Meng H, Helbling DC, Takizawa A, Bennett B, Garces AM, Dias Duarte Machado LG, Dimmock D, Dwinell MR, Geurts AM, Lawlor MW. Sdha+/- Rats Display Minimal Muscle Pathology Without Significant Behavioral or Biochemical Abnormalities. J Neuropathol Exp Neurol. 2018 Aug 01;77(8):665-672. PMCID: PMC6044411 |
79. The Gene Ontology Consortium. The Gene Ontology Resource: 20 years and still GOing strong. Nucleic Acids Res. 2019 Jan 08;47(D1):D330-D338. PMCID: PMC6323945 |
