Medical College of Wisconsin
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Anthony E. Zamora PhD

Anthony E. Zamora PhD

Assistant Professor

Institution: Medical College of Wisconsin
Department: Medicine
Division: Hematology and Oncology - Medicine
Program: Hematology

Member of the Cancer Center


I am willing to collaborate on research projects.


Research Experience

  • Antigen Presentation
  • CD8-Positive T-Lymphocytes
  • Cell Engineering
  • Disease Models, Animal
  • Flow Cytometry
  • Immunity
  • Immunotherapy
  • Killer Cells, Natural
  • Leukemia, B-Cell
  • Single-Cell Analysis
  • T-Lymphocytes
  • immunology
  • Publications (17)

  • Pediatric patients with acute lymphoblastic leukemia generate abundant and functional neoantigen-specific CD8+ T cell responses. (Zamora AE, Crawford JC, Allen EK, Guo XJ, Bakke J, Carter RA, Abdelsamed HA, Moustaki A, Li Y, Chang TC, Awad W, Dallas MH, Mullighan CG, Downing JR, Geiger TL, Chen T, Green DR, Youngblood BA, Zhang J, Thomas PG) Sci Transl Med 2019 06 26;11(498) PMID: 31243155 PMCID: PMC7020562 SCOPUS ID: 2-s2.0-85068363631 06/28/2019       10 Citations
  • Genome-wide CRISPR screen reveals PSMA6 to be an essential gene in pancreatic cancer cells. (Bakke J, Wright WC, Zamora AE, Oladimeji P, Crawford JC, Brewer CT, Autry RJ, Evans WE, Thomas PG, Chen T) BMC Cancer 2019 Mar 21;19(1):253 PMID: 30898113 PMCID: PMC6429770 SCOPUS ID: 2-s2.0-85063331223 03/23/2019       5 Citations
  • Lung γδ T Cells Mediate Protective Responses during Neonatal Influenza Infection that Are Associated with Type 2 Immunity. (Guo XJ, Dash P, Crawford JC, Allen EK, Zamora AE, Boyd DF, Duan S, Bajracharya R, Awad WA, Apiwattanakul N, Vogel P, Kanneganti TD, Thomas PG) Immunity 2018 09 18;49(3):531-544.e6 PMID: 30170813 PMCID: PMC6345262 SCOPUS ID: 2-s2.0-85055586852 09/02/2018       15 Citations
  • Hitting the Target: How T Cells Detect and Eliminate Tumors. (Zamora AE, Crawford JC, Thomas PG) J Immunol 2018 01 15;200(2):392-399 PMID: 29311380 PMCID: PMC6116355 SCOPUS ID: 2-s2.0-85044719192 01/10/2018       13 Citations
  • Transcription factor ZNF148 is a negative regulator of human muscle differentiation. (Bakke J, Wright WC, Zamora AE, Ong SS, Wang YM, Hoyer JD, Brewer CT, Thomas PG, Chen T) Sci Rep 2017 08 15;7(1):8138 PMID: 28811660 PMCID: PMC5557752 SCOPUS ID: 2-s2.0-85027508922 08/16/2017       2 Citations
  • SNP-mediated disruption of CTCF binding at the IFITM3 promoter is associated with risk of severe influenza in humans. (Allen EK, Randolph AG, Bhangale T, Dogra P, Ohlson M, Oshansky CM, Zamora AE, Shannon JP, Finkelstein D, Dressen A, DeVincenzo J, Caniza M, Youngblood B, Rosenberger CM, Thomas PG) Nat Med 2017 Aug;23(8):975-983 PMID: 28714988 PMCID: PMC5702558 SCOPUS ID: 2-s2.0-85029295000 07/18/2017       47 Citations
  • Licensing delineates helper and effector NK cell subsets during viral infection. (Zamora AE, Aguilar EG, Sungur CM, Khuat LT, Dunai C, Lochhead GR, Du J, Pomeroy C, Blazar BR, Longo DL, Venstrom JM, Baumgarth N, Murphy WJ) JCI Insight 2017 May 18;2(10) PMID: 28515356 PMCID: PMC5436543 SCOPUS ID: 2-s2.0-85034247888 05/19/2017       13 Citations
  • Cell-Intrinsic Barriers of T Cell-Based Immunotherapy. (Ghoneim HE, Zamora AE, Thomas PG, Youngblood BA) Trends Mol Med 2016 12;22(12):1000-1011 PMID: 27825667 PMCID: PMC5135632 SCOPUS ID: 2-s2.0-84999792425 11/09/2016       22 Citations
  • Blocking Indolamine-2,3-Dioxygenase Rebound Immune Suppression Boosts Antitumor Effects of Radio-Immunotherapy in Murine Models and Spontaneous Canine Malignancies. (Monjazeb AM, Kent MS, Grossenbacher SK, Mall C, Zamora AE, Mirsoian A, Chen M, Kol A, Shiao SL, Reddy A, Perks JR, T N Culp W, Sparger EE, Canter RJ, Sckisel GD, Murphy WJ) Clin Cancer Res 2016 Sep 01;22(17):4328-40 PMID: 26979392 PMCID: PMC5010514 SCOPUS ID: 2-s2.0-84988584598 03/17/2016       41 Citations
  • Models to Study NK Cell Biology and Possible Clinical Application. (Zamora AE, Grossenbacher SK, Aguilar EG, Murphy WJ) Curr Protoc Immunol 2015 Aug 03;110:14.37.1-14.37.14 PMID: 26237009 PMCID: PMC4772895 SCOPUS ID: 2-s2.0-84949256486 08/04/2015       5 Citations
  • Bystander activation and anti-tumor effects of CD8+ T cells following Interleukin-2 based immunotherapy is independent of CD4+ T cell help. (Monjazeb AM, Tietze JK, Grossenbacher SK, Hsiao HH, Zamora AE, Mirsoian A, Koehn B, Blazar BR, Weiss JM, Wiltrout RH, Sckisel GD, Murphy WJ) PLoS One 2014;9(8):e102709 PMID: 25119341 PMCID: PMC4131875 SCOPUS ID: 2-s2.0-84905919686 08/15/2014       13 Citations
  • Impact of ageing and body mass on cancer immunotherapy outcomes (Sckisel GD, Monjazeb AM, Mirsoian A, Zamora AE, Grossenbacher S, Murphy WJ) ,Tumor Immunology and Immunotherapy, pp.15-30, Oxford: Oxford University Press 07/29/2014    
  • Impact of obesity and aging on the tumor immuno-environment (Mirsoian A, Sckisel GD, Zamora AE, Murphy WJ) The Tumor Immunoenvironment 1 January 2014:223-250 SCOPUS ID: 2-s2.0-84932114168 01/01/2014    
  • Aging predisposes to acute inflammatory induced pathology after tumor immunotherapy. (Bouchlaka MN, Sckisel GD, Chen M, Mirsoian A, Zamora AE, Maverakis E, Wilkins DE, Alderson KL, Hsiao HH, Weiss JM, Monjazeb AM, Hesdorffer C, Ferrucci L, Longo DL, Blazar BR, Wiltrout RH, Redelman D, Taub DD, Murphy WJ) J Exp Med 2013 Oct 21;210(11):2223-37 PMID: 24081947 PMCID: PMC3804937 SCOPUS ID: 2-s2.0-84885783438 10/02/2013       65 Citations
  • Influenza infection results in local expansion of memory CD8(+) T cells with antigen non-specific phenotype and function. (Sckisel GD, Tietze JK, Zamora AE, Hsiao HH, Priest SO, Wilkins DE, Lanier LL, Blazar BR, Baumgarth N, Murphy WJ) Clin Exp Immunol 2014 Jan;175(1):79-91 PMID: 23937663 PMCID: PMC3898557 SCOPUS ID: 2-s2.0-84888857737 08/14/2013       17 Citations
  • Immunoediting and antigen loss: overcoming the achilles heel of immunotherapy with antigen non-specific therapies. (Monjazeb AM, Zamora AE, Grossenbacher SK, Mirsoian A, Sckisel GD, Murphy WJ) Front Oncol 2013;3:197 PMID: 23898464 PMCID: PMC3724213 07/31/2013    
  • Murine NK-cell licensing is reflective of donor MHC-I following allogeneic hematopoietic stem cell transplantation in murine cytomegalovirus responses. (Sungur CM, Tang-Feldman YJ, Zamora AE, Alvarez M, Pomeroy C, Murphy WJ) Blood 2013 Aug 22;122(8):1518-21 PMID: 23818546 PMCID: PMC3750345 SCOPUS ID: 2-s2.0-84886852339 07/03/2013       15 Citations
  • Last update: 04/15/2020
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