Medical College of Wisconsin
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Eillen Tecle PhD

Eillen Tecle PhD profile photo picture

Assistant Professor

Institution: Medical College of Wisconsin
Department: Microbiology and Immunology

View Curriculum Vitae

Research Areas of Interest

  • Caenorhabditis elegans
  • Gastrointestinal Tract
  • Heparan Sulfate Proteoglycans
  • Host-Pathogen Interactions
  • Microsporidia
  • Microsporidiosis
  • Purine Nucleosides
  • Purine-Nucleoside Phosphorylase
  • Purine-Pyrimidine Metabolism, Inborn Errors

    • MCW Program / Core Facilities

  • Center for Immunology
  • Center for Infectious Disease Research

    • Publications (10)

  • Adenosine deaminase and deoxyadenosine regulate intracellular immune response in C. elegans. (Wernet ND, Tecle E, Sarmiento MB, Kuo CJ, Chhan CB, Baick I, Batachari LE, Franklin L, Herneisen A, Bhabha G, Ekiert DC, Hanna-Rose W, Troemel ER) iScience 2025 Mar 21;28(3):111950 PMID: 40034845 PMCID: PMC11872409 SCOPUS ID: 2-s2.0-85217752665 03/04/2025       1 Citation
  • Insights from C. elegans into Microsporidia Biology and Host-Pathogen Relationships. (Tecle E, Troemel ER) Exp Suppl 2022;114:115-136 PMID: 35544001 PMCID: PMC9208714 SCOPUS ID: 2-s2.0-85129971547 05/12/2022       20 Citations
  • The purine nucleoside phosphorylase pnp-1 regulates epithelial cell resistance to infection in C. elegans. (Tecle E, Chhan CB, Franklin L, Underwood RS, Hanna-Rose W, Troemel ER) PLoS Pathog 2021 Apr;17(4):e1009350 PMID: 33878133 PMCID: PMC8087013 SCOPUS ID: 2-s2.0-85104959353 04/21/2021       37 Citations
  • The Caenorhabditis elegans RIG-I Homolog DRH-1 Mediates the Intracellular Pathogen Response upon Viral Infection. (Sowa JN, Jiang H, Somasundaram L, Tecle E, Xu G, Wang D, Troemel ER) J Virol 2020 Jan 06;94(2) PMID: 31619561 PMCID: PMC6955277 SCOPUS ID: 2-s2.0-85077667459 10/18/2019       50 Citations
  • The female reproductive tract contains multiple innate sialic acid-binding immunoglobulin-like lectins (Siglecs) that facilitate sperm survival. (Tecle E, Reynoso HS, Wang R, Gagneux P) J Biol Chem 2019 Aug 02;294(31):11910-11919 PMID: 31201275 PMCID: PMC6682739 SCOPUS ID: 2-s2.0-85070756446 06/16/2019       34 Citations
  • Coordination of Heparan Sulfate Proteoglycans with Wnt Signaling To Control Cellular Migrations and Positioning in Caenorhabditis elegans. (Saied-Santiago K, Townley RA, Attonito JD, da Cunha DS, Díaz-Balzac CA, Tecle E, Bülow HE) Genetics 2017 Aug;206(4):1951-1967 PMID: 28576860 PMCID: PMC5560800 SCOPUS ID: 2-s2.0-85027049485 06/04/2017       22 Citations
  • Sugar-coated sperm: Unraveling the functions of the mammalian sperm glycocalyx. (Tecle E, Gagneux P) Mol Reprod Dev 2015 Sep;82(9):635-50 PMID: 26061344 PMCID: PMC4744710 SCOPUS ID: 2-s2.0-84941731922 06/11/2015       132 Citations
  • Complex cooperative functions of heparan sulfate proteoglycans shape nervous system development in Caenorhabditis elegans. (Díaz-Balzac CA, Lázaro-Peña MI, Tecle E, Gomez N, Bülow HE) G3 (Bethesda) 2014 Aug 05;4(10):1859-70 PMID: 25098771 PMCID: PMC4199693 SCOPUS ID: 2-s2.0-84908452908 08/08/2014       31 Citations
  • Skin-derived cues control arborization of sensory dendrites in Caenorhabditis elegans. (Salzberg Y, Díaz-Balzac CA, Ramirez-Suarez NJ, Attreed M, Tecle E, Desbois M, Kaprielian Z, Bülow HE) Cell 2013 Oct 10;155(2):308-20 PMID: 24120132 PMCID: PMC3881433 SCOPUS ID: 2-s2.0-84885673994 10/15/2013       124 Citations
  • Distinct 3-O-sulfated heparan sulfate modification patterns are required for kal-1-dependent neurite branching in a context-dependent manner in Caenorhabditis elegans. (Tecle E, Diaz-Balzac CA, Bülow HE) G3 (Bethesda) 2013 Mar;3(3):541-52 PMID: 23451335 PMCID: PMC3583460 SCOPUS ID: 2-s2.0-84883234314 03/02/2013       32 Citations
    • Last update: 03/04/2025