Medical College of Wisconsin
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Jenifer Coburn PhD

Professor

Institution: Medical College of Wisconsin
Department: Medicine
Division: Infectious Disease
Program: Research


Research Experience

  • Borrelia Infections
  • Spirochaetales Infections
  • Tick-Borne Diseases
  • Publications (79)

  • Identification of amino acid domains of Borrelia burgdorferi P66 that are surface exposed and important for localization, oligomerization, and porin function of the protein. (Curtis MW, Fierros CH, Hahn BL, Surdel MC, Kessler J, Anderson PN, Vandewalle-Capo M, Bonde M, Zhu J, Bergström S, Coburn J) Front Cell Infect Microbiol 2022;12:991689 PMID: 36211976 PMCID: PMC9539438 SCOPUS ID: 2-s2.0-85139437187 10/11/2022       1 Citation
  • Heterologous production of the adhesin LIC13411 from pathogenic Leptospira facilitates binding of non-pathogenic Leptospira in vitro and in vivo. (Surdel MC, Hahn BL, Anderson PN, Coburn J) Front Cell Infect Microbiol 2022;12:917963 PMID: 35937702 PMCID: PMC9354625 SCOPUS ID: 2-s2.0-85135274644 08/09/2022       2 Citations
  • Hematogenous dissemination of pathogenic and non-pathogenic Leptospira in a short-term murine model of infection. (Surdel MC, Anderson PN, Hahn BL, Coburn J) Front Cell Infect Microbiol 2022;12:917962 PMID: 35923802 PMCID: PMC9339599 SCOPUS ID: 2-s2.0-85135250975 08/05/2022       1 Citation
  • VlsE, the nexus for antigenic variation of the Lyme disease spirochete, also mediates early bacterial attachment to the host microvasculature under shear force. (Tan X, Lin YP, Pereira MJ, Castellanos M, Hahn BL, Anderson P, Coburn J, Leong JM, Chaconas G) PLoS Pathog 2022 May;18(5):e1010511 PMID: 35605029 PMCID: PMC9166660 SCOPUS ID: 2-s2.0-85131457166 05/24/2022    
  • Pathogenesis insights from an ancient and ubiquitous spirochete. (Coburn J, Picardeau M, Woods CW, Veldman T, Haake DA) PLoS Pathog 2021 Oct;17(10):e1009836 PMID: 34673833 PMCID: PMC8530280 SCOPUS ID: 2-s2.0-85118294631 10/22/2021       1 Citation
  • Lyme Disease Pathogenesis. (Coburn J, Garcia B, Hu LT, Jewett MW, Kraiczy P, Norris SJ, Skare J) Curr Issues Mol Biol 2021;42:473-518 PMID: 33353871 PMCID: PMC8046170 SCOPUS ID: 2-s2.0-85102523563 12/24/2020       25 Citations
  • BBB07 contributes to, but is not essential for, Borrelia burgdorferi infection in mice. (Hahn B, Anderson P, Lu Z, Danner R, Zhou Z, Hyun N, Gao L, Lin T, Norris SJ, Coburn J) Microbiology (Reading) 2020 Oct;166(10):988-994 PMID: 32936070 PMCID: PMC7660918 SCOPUS ID: 2-s2.0-85094983555 09/17/2020    
  • Method to Overcome Inefficiencies in Site-Directed Mutagenesis of A/T-Rich DNA. (DeCero SA 2nd, Winslow CH, Coburn J) J Biomol Tech 2020 Sep;31(3):94-99 PMID: 32831656 PMCID: PMC7351327 SCOPUS ID: 2-s2.0-85091559248 08/25/2020    
  • Strain-specific joint invasion and colonization by Lyme disease spirochetes is promoted by outer surface protein C. (Lin YP, Tan X, Caine JA, Castellanos M, Chaconas G, Coburn J, Leong JM) PLoS Pathog 2020 May;16(5):e1008516 PMID: 32413091 PMCID: PMC7255614 SCOPUS ID: 2-s2.0-85085664567 05/16/2020       15 Citations
  • Recent discoveries and advancements in research on the Lyme disease spirochete Borrelia burgdorferi. (Winslow C, Coburn J) F1000Res 2019;8 PMID: 31214329 PMCID: PMC6545822 SCOPUS ID: 2-s2.0-85067361276 06/20/2019       4 Citations
  • An extracellular Leptospira interrogans leucine-rich repeat protein binds human E- and VE-cadherins. (Eshghi A, Gaultney RA, England P, Brûlé S, Miras I, Sato H, Coburn J, Bellalou J, Moriarty TJ, Haouz A, Picardeau M) Cell Microbiol 2019 Feb;21(2):e12949 PMID: 30171791 PMCID: PMC7560960 SCOPUS ID: 2-s2.0-85053836084 09/02/2018       15 Citations
  • Characterization of Stress and Innate Immunity Resistance of Wild-Type and Δp66 Borrelia burgdorferi. (Curtis MW, Hahn BL, Zhang K, Li C, Robinson RT, Coburn J) Infect Immun 2018 Feb;86(2) PMID: 29158430 PMCID: PMC5778354 SCOPUS ID: 2-s2.0-85040966556 11/22/2017       10 Citations
  • Borrelia burgdorferi outer surface protein C (OspC) binds complement component C4b and confers bloodstream survival. (Caine JA, Lin YP, Kessler JR, Sato H, Leong JM, Coburn J) Cell Microbiol 2017 Dec;19(12) PMID: 28873507 PMCID: PMC5680108 SCOPUS ID: 2-s2.0-85033218000 09/06/2017       48 Citations
  • Leptospira interrogans causes quantitative and morphological disturbances in adherens junctions and other biological groups of proteins in human endothelial cells. (Sato H, Coburn J) PLoS Negl Trop Dis 2017 Jul;11(7):e0005830 PMID: 28750011 PMCID: PMC5549773 SCOPUS ID: 2-s2.0-85026749284 07/28/2017       22 Citations
  • Multifunctional and Redundant Roles of Borrelia burgdorferi Outer Surface Proteins in Tissue Adhesion, Colonization, and Complement Evasion. (Caine JA, Coburn J) Front Immunol 2016;7:442 PMID: 27818662 PMCID: PMC5073149 SCOPUS ID: 2-s2.0-84997170519 11/08/2016       32 Citations
  • Lyme Disease (Lu Z, Coburn J) International Encyclopedia of Public Health 6 October 2016:495-503 SCOPUS ID: 2-s2.0-85043351109 10/06/2016    
  • Live Attenuated Borrelia burgdorferi Targeted Mutants in an Infectious Strain Background Protect Mice from Challenge Infection. (Hahn BL, Padmore LJ, Ristow LC, Curtis MW, Coburn J) Clin Vaccine Immunol 2016 Aug;23(8):725-31 PMID: 27335385 PMCID: PMC4979176 SCOPUS ID: 2-s2.0-84982994177 06/24/2016       6 Citations
  • Glycosaminoglycan binding by the lyme disease spirochete is a determinant of tissue tropism and disease (Lin YP, Osburne MS, Pereira MJ, Coburn J, Leong JM) Glycobiology and Human Diseases 22 February 2016:86-96 SCOPUS ID: 2-s2.0-85034994345 02/22/2016       1 Citation
  • Intravital Imaging of Vascular Transmigration by the Lyme Spirochete: Requirement for the Integrin Binding Residues of the B. burgdorferi P66 Protein. (Kumar D, Ristow LC, Shi M, Mukherjee P, Caine JA, Lee WY, Kubes P, Coburn J, Chaconas G) PLoS Pathog 2015 Dec;11(12):e1005333 PMID: 26684456 PMCID: PMC4686178 SCOPUS ID: 2-s2.0-84953273433 12/20/2015       32 Citations
  • A short-term Borrelia burgdorferi infection model identifies tissue tropisms and bloodstream survival conferred by adhesion proteins. (Caine JA, Coburn J) Infect Immun 2015 Aug;83(8):3184-94 PMID: 26015482 PMCID: PMC4496602 SCOPUS ID: 2-s2.0-84937811051 05/28/2015       38 Citations
  • Evaluation of cell binding activities of Leptospira ECM adhesins. (Robbins GT, Hahn BL, Evangelista KV, Padmore L, Aranda PS, Coburn J) PLoS Negl Trop Dis 2015 Apr;9(4):e0003712 PMID: 25875373 PMCID: PMC4397020 SCOPUS ID: 2-s2.0-84929493843 04/16/2015       24 Citations
  • Host cell heparan sulfate glycosaminoglycans are ligands for OspF-related proteins of the Lyme disease spirochete. (Lin YP, Bhowmick R, Coburn J, Leong JM) Cell Microbiol 2015 Oct;17(10):1464-76 PMID: 25864455 PMCID: PMC4583806 SCOPUS ID: 2-s2.0-84942195719 04/14/2015       23 Citations
  • Integrin binding by Borrelia burgdorferi P66 facilitates dissemination but is not required for infectivity. (Ristow LC, Bonde M, Lin YP, Sato H, Curtis M, Wesley E, Hahn BL, Fang J, Wilcox DA, Leong JM, Bergström S, Coburn J) Cell Microbiol 2015 Jul;17(7):1021-36 PMID: 25604835 PMCID: PMC4478124 SCOPUS ID: 2-s2.0-84931571353 01/22/2015       35 Citations
  • Glycosaminoglycan binding by Borrelia burgdorferi adhesin BBK32 specifically and uniquely promotes joint colonization. (Lin YP, Chen Q, Ritchie JA, Dufour NP, Fischer JR, Coburn J, Leong JM) Cell Microbiol 2015 Jun;17(6):860-75 PMID: 25486989 PMCID: PMC4437914 SCOPUS ID: 2-s2.0-84929498420 12/10/2014       51 Citations
  • Reproducible and quantitative model of infection of Dermacentor variabilis with the live vaccine strain of Francisella tularensis. (Coburn J, Maier T, Casey M, Padmore L, Sato H, Frank DW) Appl Environ Microbiol 2015 Jan;81(1):386-95 PMID: 25362054 PMCID: PMC4272728 SCOPUS ID: 2-s2.0-84917707073 11/02/2014       7 Citations
  • Identification of cell-binding adhesins of Leptospira interrogans. (Evangelista KV, Hahn B, Wunder EA Jr, Ko AI, Haake DA, Coburn J) PLoS Negl Trop Dis 2014 Oct;8(10):e3215 PMID: 25275630 PMCID: PMC4183468 SCOPUS ID: 2-s2.0-84920527866 10/03/2014       25 Citations
  • Leptospira interrogans binds to cadherins. (Evangelista K, Franco R, Schwab A, Coburn J) PLoS Negl Trop Dis 2014;8(1):e2672 PMID: 24498454 PMCID: PMC3907533 SCOPUS ID: 2-s2.0-84893799614 02/06/2014       40 Citations
  • Illuminating the roles of the Borrelia burgdorferi adhesins. (Coburn J, Leong J, Chaconas G) Trends Microbiol 2013 Aug;21(8):372-9 PMID: 23876218 PMCID: PMC3773214 SCOPUS ID: 2-s2.0-84881028121 07/24/2013       59 Citations
  • Borrelia burgdorferi and lyme disease (Jewett MW, Coburn J, Leong J) Schaechter's Mechanisms of Microbial Disease: Fifth Edition 8 July 2013:277-286 SCOPUS ID: 2-s2.0-84971290792 07/08/2013    
  • The β₃-integrin ligand of Borrelia burgdorferi is critical for infection of mice but not ticks. (Ristow LC, Miller HE, Padmore LJ, Chettri R, Salzman N, Caimano MJ, Rosa PA, Coburn J) Mol Microbiol 2012 Sep;85(6):1105-18 PMID: 22758390 PMCID: PMC3438374 SCOPUS ID: 2-s2.0-84866024708 07/05/2012       45 Citations
  • Borrelia burgdorferi and lyme disease (Jewett MW, Coburn J, Leong J) Schaechter's Mechanisms of Microbial Disease: Fifth Edition 15 May 2012:277-286 SCOPUS ID: 2-s2.0-84971238722 05/15/2012    
  • The Borrelia burgdorferi integrin ligand P66 affects gene expression by human cells in culture. (LaFrance ME, Pierce JV, Antonara S, Coburn J) Infect Immun 2011 Aug;79(8):3249-61 PMID: 21576330 PMCID: PMC3147572 SCOPUS ID: 2-s2.0-79961115580 05/18/2011       15 Citations
  • Adhesion mechanisms of Borrelia burgdorferi. (Antonara S, Ristow L, Coburn J) Adv Exp Med Biol 2011;715:35-49 PMID: 21557056 PMCID: PMC4521209 SCOPUS ID: 2-s2.0-79960126040 05/11/2011       33 Citations
  • The emergence of severe pulmonary hemorrhagic leptospirosis: questions to consider. (Truong KN, Coburn J) Front Cell Infect Microbiol 2011;1:24 PMID: 22919589 PMCID: PMC3417368 SCOPUS ID: 2-s2.0-84879538428 01/01/2011       11 Citations
  • Responses of human endothelial cells to pathogenic and non-pathogenic Leptospira species. (Martinez-Lopez DG, Fahey M, Coburn J) PLoS Negl Trop Dis 2010 Dec 14;4(12):e918 PMID: 21179504 PMCID: PMC3001904 SCOPUS ID: 2-s2.0-78650714951 12/24/2010       40 Citations
  • Leptospira as an emerging pathogen: a review of its biology, pathogenesis and host immune responses. (Evangelista KV, Coburn J) Future Microbiol 2010 Sep;5(9):1413-25 PMID: 20860485 PMCID: PMC3037011 SCOPUS ID: 2-s2.0-77957582069 09/24/2010       232 Citations
  • Effect of Borrelia burgdorferi OspC at the site of inoculation in mouse skin. (Antonara S, Ristow L, McCarthy J, Coburn J) Infect Immun 2010 Nov;78(11):4723-33 PMID: 20696825 PMCID: PMC2976318 SCOPUS ID: 2-s2.0-78049430771 08/11/2010       25 Citations
  • Interaction of Borrelia burgdorferi Hbb with the p66 promoter. (Medrano MS, Policastro PF, Schwan TG, Coburn J) Nucleic Acids Res 2010 Jan;38(2):414-27 PMID: 19910373 PMCID: PMC2811001 SCOPUS ID: 2-s2.0-77449098641 11/17/2009       16 Citations
  • Leptospira interrogans binds to human cell surface receptors including proteoglycans. (Breiner DD, Fahey M, Salvador R, Novakova J, Coburn J) Infect Immun 2009 Dec;77(12):5528-36 PMID: 19805539 PMCID: PMC2786458 SCOPUS ID: 2-s2.0-72449201064 10/07/2009       35 Citations
  • High prevalence of spirochetosis in cholera patients, Bangladesh. (Nelson EJ, Tanudra A, Chowdhury A, Kane AV, Qadri F, Calderwood SB, Coburn J, Camilli A) Emerg Infect Dis 2009 Apr;15(4):571-3 PMID: 19331734 PMCID: PMC2671413 SCOPUS ID: 2-s2.0-65349094714 04/01/2009       10 Citations
  • Lyme disease (Rosenthal M, Coburn J) International Encyclopedia of Public Health 2008:168-176 SCOPUS ID: 2-s2.0-84884460305 12/01/2008    
  • Borrelia burgdorferi BBB07 interaction with integrin alpha3beta1 stimulates production of pro-inflammatory mediators in primary human chondrocytes. (Behera AK, Durand E, Cugini C, Antonara S, Bourassa L, Hildebrand E, Hu LT, Coburn J) Cell Microbiol 2008 Feb;10(2):320-31 PMID: 17822440 PMCID: PMC2586958 SCOPUS ID: 2-s2.0-38049107588 09/08/2007       60 Citations
  • Borrelia burgdorferi adhesins identified using in vivo phage display. (Antonara S, Chafel RM, LaFrance M, Coburn J) Mol Microbiol 2007 Oct;66(1):262-76 PMID: 17784908 PMCID: PMC2651023 SCOPUS ID: 2-s2.0-34548694325 09/06/2007       74 Citations
  • Regulators of expression of the oligopeptide permease A proteins of Borrelia burgdorferi. (Medrano MS, Ding Y, Wang XG, Lu P, Coburn J, Hu LT) J Bacteriol 2007 Apr;189(7):2653-9 PMID: 17237172 PMCID: PMC1855802 SCOPUS ID: 2-s2.0-34147117599 01/24/2007       44 Citations
  • Elimination of channel-forming activity by insertional inactivation of the p66 gene in Borrelia burgdorferi. (Pinne M, Thein M, Denker K, Benz R, Coburn J, Bergström S) FEMS Microbiol Lett 2007 Jan;266(2):241-9 PMID: 17233736 SCOPUS ID: 2-s2.0-33845650737 01/20/2007       32 Citations
  • Short report: Association of macrophage inflammatory response and cell death after in vitro Borrelia burgdorferi infection with arthritis resistance. (Glickstein LJ, Coburn JL) Am J Trop Med Hyg 2006 Nov;75(5):964-7 PMID: 17123997 SCOPUS ID: 2-s2.0-34247192311 11/25/2006       12 Citations
  • Identification of a TLR-independent pathway for Borrelia burgdorferi-induced expression of matrix metalloproteinases and inflammatory mediators through binding to integrin alpha 3 beta 1. (Behera AK, Hildebrand E, Uematsu S, Akira S, Coburn J, Hu LT) J Immunol 2006 Jul 01;177(1):657-64 PMID: 16785564 SCOPUS ID: 2-s2.0-33745320471 06/21/2006       54 Citations
  • Solving a sticky problem: new genetic approaches to host cell adhesion by the Lyme disease spirochete. (Coburn J, Fischer JR, Leong JM) Mol Microbiol 2005 Sep;57(5):1182-95 PMID: 16101994 SCOPUS ID: 2-s2.0-23844515087 08/17/2005       78 Citations
  • Borrelia burgdorferi, an extracellular pathogen, circumvents osteopontin in inducing an inflammatory cytokine response. (Craig-Mylius K, Weber GF, Coburn J, Glickstein L) J Leukoc Biol 2005 May;77(5):710-8 PMID: 15695554 SCOPUS ID: 2-s2.0-18244396334 02/08/2005       12 Citations
  • The emergence of Lyme disease. (Steere AC, Coburn J, Glickstein L) J Clin Invest 2004 Apr;113(8):1093-101 PMID: 15085185 PMCID: PMC385417 SCOPUS ID: 2-s2.0-2142660806 04/16/2004       601 Citations
  • Characterization of Pseudomonas aeruginosa exoenzyme S as a bifunctional enzyme in J774A.1 macrophages. (Rocha CL, Coburn J, Rucks EA, Olson JC) Infect Immun 2003 Sep;71(9):5296-305 PMID: 12933877 PMCID: PMC187317 SCOPUS ID: 2-s2.0-0041322625 08/23/2003       48 Citations
  • Targeted mutation of the outer membrane protein P66 disrupts attachment of the Lyme disease agent, Borrelia burgdorferi, to integrin alphavbeta3. (Coburn J, Cugini C) Proc Natl Acad Sci U S A 2003 Jun 10;100(12):7301-6 PMID: 12748384 PMCID: PMC165870 SCOPUS ID: 2-s2.0-0038809086 05/16/2003       88 Citations
  • Regulation of expression of the Borrelia burgdorferi beta(3)-chain integrin ligand, P66, in ticks and in culture. (Cugini C, Medrano M, Schwan TG, Coburn J) Infect Immun 2003 Feb;71(2):1001-7 PMID: 12540584 PMCID: PMC145366 SCOPUS ID: 2-s2.0-0037306601 01/24/2003       41 Citations
  • Adhesion mechanisms of the Lyme disease spirochete, Borrelia burgdorferi. (Coburn J) Curr Drug Targets Infect Disord 2001 Aug;1(2):171-9 PMID: 12455413 SCOPUS ID: 2-s2.0-0035428016 11/29/2002       16 Citations
  • Borrelia burgdorferi and its tropisms for adhesion molecules in the joint. (Coburn J, Medrano M, Cugini C) Curr Opin Rheumatol 2002 Jul;14(4):394-8 PMID: 12118173 SCOPUS ID: 2-s2.0-0035985830 07/16/2002       20 Citations
  • Delineation of Borrelia burgdorferi p66 sequences required for integrin alpha(IIb)beta(3) recognition. (Defoe G, Coburn J) Infect Immun 2001 May;69(5):3455-9 PMID: 11292775 PMCID: PMC98311 SCOPUS ID: 2-s2.0-0035055365 04/09/2001       43 Citations
  • Microbiology. Arresting features of bacterial toxins. (Coburn J, Leong JM) Science 2000 Oct 13;290(5490):287-8 PMID: 11183375 SCOPUS ID: 2-s2.0-0034644599 02/24/2001       5 Citations
  • Recognition of multiple antibody epitopes throughout Borrelia burgdorferi p66, a candidate adhesin, in patients with early or late manifestations of Lyme disease. (Ntchobo H, Rothermel H, Chege W, Steere AC, Coburn J) Infect Immun 2001 Mar;69(3):1953-6 PMID: 11179382 PMCID: PMC98111 SCOPUS ID: 2-s2.0-0035112447 02/17/2001       21 Citations
  • Platelet activation by a relapsing fever spirochaete results in enhanced bacterium-platelet interaction via integrin alphaIIbbeta3 activation. (Alugupalli KR, Michelson AD, Barnard MR, Robbins D, Coburn J, Baker EK, Ginsberg MH, Schwan TG, Leong JM) Mol Microbiol 2001 Jan;39(2):330-40 PMID: 11136454 SCOPUS ID: 2-s2.0-0035151055 01/03/2001       35 Citations
  • Prominent expression of mRNA for proinflammatory cytokines in synovium in patients with juvenile rheumatoid arthritis or chronic Lyme arthritis. (Harjacek M, Diaz-Cano S, Alman BA, Coburn J, Ruthazer R, Wolfe H, Steere AC) J Rheumatol 2000 Feb;27(2):497-503 PMID: 10685820 SCOPUS ID: 2-s2.0-0033951326 02/24/2000       43 Citations
  • Lack of Borrelia burgdorferi DNA in synovial samples from patients with antibiotic treatment-resistant Lyme arthritis. (Carlson D, Hernandez J, Bloom BJ, Coburn J, Aversa JM, Steere AC) Arthritis Rheum 1999 Dec;42(12):2705-9 PMID: 10616021 SCOPUS ID: 2-s2.0-0033511725 01/01/2000       102 Citations
  • Characterization of a candidate Borrelia burgdorferi beta3-chain integrin ligand identified using a phage display library. (Coburn J, Chege W, Magoun L, Bodary SC, Leong JM) Mol Microbiol 1999 Dec;34(5):926-40 PMID: 10594819 SCOPUS ID: 2-s2.0-0033233457 12/14/1999       101 Citations
  • Macrophages and epithelial cells respond differently to the Pseudomonas aeruginosa type III secretion system. (Coburn J, Frank DW) Infect Immun 1999 Jun;67(6):3151-4 PMID: 10338535 PMCID: PMC96636 SCOPUS ID: 2-s2.0-0033031869 05/25/1999       62 Citations
  • A natural variant of the cysteine protease virulence factor of group A Streptococcus with an arginine-glycine-aspartic acid (RGD) motif preferentially binds human integrins alphavbeta3 and alphaIIbbeta3. (Stockbauer KE, Magoun L, Liu M, Burns EH Jr, Gubba S, Renish S, Pan X, Bodary SC, Baker E, Coburn J, Leong JM, Musser JM) Proc Natl Acad Sci U S A 1999 Jan 05;96(1):242-7 PMID: 9874803 PMCID: PMC15124 SCOPUS ID: 2-s2.0-0033524449 01/06/1999       87 Citations
  • Integrins alpha(v)beta3 and alpha5beta1 mediate attachment of lyme disease spirochetes to human cells. (Coburn J, Magoun L, Bodary SC, Leong JM) Infect Immun 1998 May;66(5):1946-52 PMID: 9573074 PMCID: PMC108148 SCOPUS ID: 2-s2.0-0031924314 05/09/1998       107 Citations
  • Different classes of proteoglycans contribute to the attachment of Borrelia burgdorferi to cultured endothelial and brain cells. (Leong JM, Wang H, Magoun L, Field JA, Morrissey PE, Robbins D, Tatro JB, Coburn J, Parveen N) Infect Immun 1998 Mar;66(3):994-9 PMID: 9488387 PMCID: PMC108007 SCOPUS ID: 2-s2.0-0031888094 03/06/1998       76 Citations
  • Hemagglutination and proteoglycan binding by the Lyme disease spirochete, Borrelia burgdorferi. (Leong JM, Morrissey PE, Ortega-Barria E, Pereira ME, Coburn J) Infect Immun 1995 Mar;63(3):874-83 PMID: 7532628 PMCID: PMC173084 SCOPUS ID: 2-s2.0-0028915849 03/01/1995       77 Citations
  • Diverse Lyme disease spirochetes bind integrin alpha IIb beta 3 on human platelets. (Coburn J, Barthold SW, Leong JM) Infect Immun 1994 Dec;62(12):5559-67 PMID: 7525486 PMCID: PMC303302 SCOPUS ID: 2-s2.0-0028062089 12/01/1994       63 Citations
  • Integrin alpha IIb beta 3 mediates binding of the Lyme disease agent Borrelia burgdorferi to human platelets. (Coburn J, Leong JM, Erban JK) Proc Natl Acad Sci U S A 1993 Aug 01;90(15):7059-63 PMID: 8394007 PMCID: PMC47075 SCOPUS ID: 2-s2.0-0027205383 08/01/1993       140 Citations
  • The eukaryotic host factor that activates exoenzyme S of Pseudomonas aeruginosa is a member of the 14-3-3 protein family. (Fu H, Coburn J, Collier RJ) Proc Natl Acad Sci U S A 1993 Mar 15;90(6):2320-4 PMID: 8460141 PMCID: PMC46078 SCOPUS ID: 2-s2.0-0027461546 03/15/1993       217 Citations
  • Pseudomonas aeruginosa exoenzyme S. (Coburn J) Curr Top Microbiol Immunol 1992;175:133-43 PMID: 1321018 SCOPUS ID: 2-s2.0-0026525869 01/01/1992       37 Citations
  • ADP-ribosylation of p21ras and related proteins by Pseudomonas aeruginosa exoenzyme S. (Coburn J, Gill DM) Infect Immun 1991 Nov;59(11):4259-62 PMID: 1937783 PMCID: PMC259026 SCOPUS ID: 2-s2.0-0025925037 11/01/1991       91 Citations
  • Pseudomonas aeruginosa exoenzyme S requires a eukaryotic protein for ADP-ribosyltransferase activity. (Coburn J, Kane AV, Feig L, Gill DM) J Biol Chem 1991 Apr 05;266(10):6438-46 PMID: 1901061 SCOPUS ID: 2-s2.0-0025809268 04/05/1991       66 Citations
  • Several GTP-binding proteins, including p21c-H-ras, are preferred substrates of Pseudomonas aeruginosa exoenzyme S. (Coburn J, Wyatt RT, Iglewski BH, Gill DM) J Biol Chem 1989 May 25;264(15):9004-8 PMID: 2498323 SCOPUS ID: 2-s2.0-0024356764 05/25/1989       90 Citations
  • Exoenzyme S of Pseudomonas aeruginosa ADP-ribosylates the intermediate filament protein vimentin. (Coburn J, Dillon ST, Iglewski BH, Gill DM) Infect Immun 1989 Mar;57(3):996-8 PMID: 2492977 PMCID: PMC313212 SCOPUS ID: 2-s2.0-0024510722 03/01/1989       69 Citations
  • ADP-ribosylation of membrane proteins by bacterial toxins in the presence of NAD glycohydrolase. (Gill DM, Coburn J) Biochim Biophys Acta 1988 Apr 28;954(1):65-72 PMID: 2833927 SCOPUS ID: 2-s2.0-0024298736 04/28/1988       13 Citations
  • Assay and purification of cytosolic factor required for cholera toxin activity. (Woolkalis M, Gill DM, Coburn J) Methods Enzymol 1988;165:246-9 PMID: 2852765 SCOPUS ID: 2-s2.0-0024259650 01/01/1988       2 Citations
  • ADP-ribosylation by cholera toxin: functional analysis of a cellular system that stimulates the enzymic activity of cholera toxin fragment A1. (Gill DM, Coburn J) Biochemistry 1987 Oct 06;26(20):6364-71 PMID: 3322378 SCOPUS ID: 2-s2.0-0023646687 10/06/1987       36 Citations
  • The differential effects of GABA-transaminase inactivation in the chick retina and brain. (Rando RR, Coburn J, Parkinson D) J Neurochem 1982 Oct;39(4):1147-51 PMID: 7119785 SCOPUS ID: 2-s2.0-0020364643 10/01/1982       4 Citations
  • Last update: 01/16/2023