Medical College of Wisconsin
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Mary F. Otterson MD

Mary F. Otterson MD


Institution: Medical College of Wisconsin
Department: Surgery
Division: Colorectal Surgery
Program: Colorectal Surgery

Member of the Cancer Center


  • Propagation of giant migrating contractions between the small intestine, cecum and colon during radiation. (Otterson MF, Leming SC, Fox CJ, Moulder JE) Neurogastroenterol Motil 2010 Aug;22(8):919-26 PMID: 20529206 PMCID: PMC4520439 06/10/2010
  • Animal models for medical countermeasures to radiation exposure. (Williams JP, Brown SL, Georges GE, Hauer-Jensen M, Hill RP, Huser AK, Kirsch DG, Macvittie TJ, Mason KA, Medhora MM, Moulder JE, Okunieff P, Otterson MF, Robbins ME, Smathers JB, McBride WH) Radiat Res 2010 Apr;173(4):557-78 PMID: 20334528 PMCID: PMC3021126 03/26/2010
  • Modulatory effect of curcumin on survival of irradiated human intestinal microvascular endothelial cells: role of Akt/mTOR and NF-{kappa}B. (Rafiee P, Binion DG, Wellner M, Behmaram B, Floer M, Mitton E, Nie L, Zhang Z, Otterson MF) Am J Physiol Gastrointest Liver Physiol 2010 Jun;298(6):G865-77 PMID: 20299603 PMCID: PMC3774333 03/20/2010
  • Chlorhexidine-Alcohol versus Povidone-Iodine for Surgical-Site Antisepsis. (Darouiche RO, Wall MJ Jr, Itani KM, Otterson MF, Webb AL, Carrick MM, Miller HJ, Awad SS, Crosby CT, Mosier MC, Alsharif A, Berger DH) N Engl J Med 2010 Jan 7;362(1):18-26 PMID: 20054046 01/08/2010
  • Thalidomide inhibits inflammatory and angiogenic activation of human intestinal microvascular endothelial cells (HIMEC). (Rafiee P, Stein DJ, Nelson VM, Otterson MF, Shaker R, Binion DG) Am J Physiol Gastrointest Liver Physiol 2010 Feb;298(2):G167-76 PMID: 19926820 PMCID: PMC2822501 11/21/2009
  • Impact of autonomic dysfunction on inflammatory bowel disease. (Ananthakrishnan AN, Issa M, Barboi A, Jaradeh S, Zadvornova Y, Skaros S, Johnson K, Otterson MF, Binion DG) J Clin Gastroenterol 2010 Apr;44(4):272-9 PMID: 19727003 09/04/2009
  • Vascular cell adhesion molecule-1 expression in human intestinal microvascular endothelial cells is regulated by PI 3-kinase/Akt/MAPK/NF-kappaB: inhibitory role of curcumin. (Binion DG, Heidemann J, Li MS, Nelson VM, Otterson MF, Rafiee P) Am J Physiol Gastrointest Liver Physiol 2009 Aug;297(2):G259-68 PMID: 19520742 PMCID: PMC2724083 06/13/2009
  • Durability of infliximab in Crohn's disease: a single-center experience. (Gonzaga JE, Ananthakrishnan AN, Issa M, Beaulieu DB, Skaros S, Zadvornova Y, Johnson K, Otterson MF, Binion DG) Inflamm Bowel Dis 2009 Dec;15(12):1837-43 PMID: 19462426 05/23/2009
  • History of medical hospitalization predicts future need for colectomy in patients with ulcerative colitis. (Ananthakrishnan AN, Issa M, Beaulieu DB, Skaros S, Knox JF, Lemke K, Emmons J, Lundeen SH, Otterson MF, Binion DG) Inflamm Bowel Dis 2009 Feb;15(2):176-81 PMID: 18680197 08/06/2008
  • Budesonide induction and maintenance therapy for Crohn's disease during pregnancy. (Beaulieu DB, Ananthakrishnan AN, Issa M, Rosenbaum L, Skaros S, Newcomer JR, Kuhlmann RS, Otterson MF, Emmons J, Knox J, Binion DG) Inflamm Bowel Dis 2009 Jan;15(1):25-8 PMID: 18680195 08/06/2008
  • Role of MutS homolog 2 (MSH2) in intestinal myofibroblast proliferation during Crohn's disease stricture formation. (Floer M, Binion DG, Nelson VM, Manley S, Wellner M, Sadeghi S, Behmaram B, Sewell C, Otterson MF, Kucharzik T, Rafiee P) Am J Physiol Gastrointest Liver Physiol 2008 Sep;295(3):G581-90 PMID: 18635600 PMCID: PMC2536780 07/19/2008
  • Curcumin inhibits VEGF-mediated angiogenesis in human intestinal microvascular endothelial cells through COX-2 and MAPK inhibition. (Binion DG, Otterson MF, Rafiee P) Gut 2008 Nov;57(11):1509-17 PMID: 18596194 PMCID: PMC2582343 07/04/2008
  • Novel method for recolonoscopy after percutaneous cecostomy. (Berger WL, Kounev V, Otterson MF) Gastrointest Endosc 2008 May;67(6):1005-6 PMID: 18243187 02/05/2008
  • Permanent work disability in Crohn's disease. (Ananthakrishnan AN, Weber LR, Knox JF, Skaros S, Emmons J, Lundeen S, Issa M, Otterson MF, Binion DG) Am J Gastroenterol 2008 Jan;103(1):154-61 PMID: 18076736 12/14/2007
  • Clinical factors contributing to rapid reoperation for Crohn's disease patients undergoing resection and/or strictureplasty. (Binion DG, Theriot KR, Shidham S, Lundeen S, Hatoum O, Lim HJ, Otterson MF) J Gastrointest Surg 2007 Dec;11(12):1692-8; dicussion 1698 PMID: 17940830 10/18/2007
  • Severe pulmonary toxicity after azathioprine/6-mercaptopurine initiation for the treatment of inflammatory bowel disease. (Ananthakrishnan AN, Attila T, Otterson MF, Lipchik RJ, Massey BT, Komorowski RA, Binion DG) J Clin Gastroenterol 2007 Aug;41(7):682-8 PMID: 17667053 08/02/2007
  • Effects of radiation upon gastrointestinal motility. (Otterson MF) World J Gastroenterol 2007 May 21;13(19):2684-92 PMID: 17569136 PMCID: PMC4147116 06/15/2007
  • Tissue and fluid penetration of garenoxacin in surgical patients. (Edmiston CE, Krepel CJ, Seabrook GR, Towne JB, Smith TL, Loehrl TA, Wackym PA, Johnson CP, Otterson MF, Gajjar DA, Krishna G) Surg Infect (Larchmt) 2007 Apr;8(2):179-88 PMID: 17437363 04/18/2007
  • Clostridium difficile enteritis: an early postoperative complication in inflammatory bowel disease patients after colectomy. (Lundeen SJ, Otterson MF, Binion DG, Carman ET, Peppard WJ) J Gastrointest Surg 2007 Feb;11(2):138-42 PMID: 17390162 03/29/2007
  • Impact of Clostridium difficile on inflammatory bowel disease. (Issa M, Vijayapal A, Graham MB, Beaulieu DB, Otterson MF, Lundeen S, Skaros S, Weber LR, Komorowski RA, Knox JF, Emmons J, Bajaj JS, Binion DG) Clin Gastroenterol Hepatol 2007 Mar;5(3):345-51 PMID: 17368234 03/21/2007
  • Increased arginase activity and endothelial dysfunction in human inflammatory bowel disease. (Horowitz S, Binion DG, Nelson VM, Kanaa Y, Javadi P, Lazarova Z, Andrekopoulos C, Kalyanaraman B, Otterson MF, Rafiee P) Am J Physiol Gastrointest Liver Physiol 2007 May;292(5):G1323-36 PMID: 17218473 01/16/2007
  • Radiation induces endothelial dysfunction in murine intestinal arterioles via enhanced production of reactive oxygen species. (Hatoum OA, Otterson MF, Kopelman D, Miura H, Sukhotnik I, Larsen BT, Selle RM, Moulder JE, Gutterman DD) Arterioscler Thromb Vasc Biol 2006 Feb;26(2):287-94 PMID: 16322529 12/03/2005
  • Novel mechanism of vasodilation in inflammatory bowel disease. (Hatoum OA, Gauthier KM, Binion DG, Miura H, Telford G, Otterson MF, Campbell WB, Gutterman DD) Arterioscler Thromb Vasc Biol 2005 Nov;25(11):2355-61 PMID: 16141408 09/06/2005
  • Radiation induced small bowel "web" formation is associated with acquired microvascular dysfunction. (Hatoum OA, Binion DG, Phillips SA, O'Loughlin C, Komorowski RA, Gutterman DD, Otterson MF) Gut 2005 Dec;54(12):1797-800 PMID: 16127018 PMCID: PMC1774807 08/30/2005
  • Transrectal and transvaginal sonographic intervention of infected pelvic fluid collections: a complete approach. (Sudakoff GS, Lundeen SJ, Otterson MF) Ultrasound Q 2005 Sep;21(3):175-85 PMID: 16096614 08/13/2005
  • Mesenteric venous thrombosis in inflammatory bowel disease. (Hatoum OA, Spinelli KS, Abu-Hajir M, Attila T, Franco J, Otterson MF, Telford GL, Binion DG) J Clin Gastroenterol 2005 Jan;39(1):27-31 PMID: 15599206 12/16/2004
  • Mechanisms of MAdCAM-1 gene expression in human intestinal microvascular endothelial cells. (Ogawa H, Binion DG, Heidemann J, Theriot M, Fisher PJ, Johnson NA, Otterson MF, Rafiee P) Am J Physiol Cell Physiol 2005 Feb;288(2):C272-81 PMID: 15483224 10/16/2004
  • Radiographic underestimation of small bowel stricturing Crohn's disease: a comparison with surgical findings. (Otterson MF, Lundeen SJ, Spinelli KS, Sudakoff GS, Telford GL, Hatoum OA, Saeian K, Yun H, Binion DG) Surgery 2004 Oct;136(4):854-60 PMID: 15467672 10/07/2004
  • Role of hydrogen peroxide in ACh-induced dilation of human submucosal intestinal microvessels. (Hatoum OA, Binion DG, Miura H, Telford G, Otterson MF, Gutterman DD) Am J Physiol Heart Circ Physiol 2005 Jan;288(1):H48-54 PMID: 15345486 09/04/2004
  • Cyclosporin A differentially inhibits multiple steps in VEGF induced angiogenesis in human microvascular endothelial cells through altered intracellular signaling. (Rafiee P, Heidemann J, Ogawa H, Johnson NA, Fisher PJ, Li MS, Otterson MF, Johnson CP, Binion DG) Cell Commun Signal 2004 Jun 2;2(1):3 PMID: 15175101 PMCID: PMC441414 06/04/2004
  • Antiangiogenic treatment of mesenteric desmoid tumors with toremifene and interferon alfa-2b: report of two cases. (Heidemann J, Ogawa H, Otterson MF, Shidham VB, Binion DG) Dis Colon Rectum 2004 Jan;47(1):118-22 PMID: 14719159 01/14/2004
  • Multivariate analysis suggests improved perioperative outcome in Crohn's disease patients receiving immunomodulator therapy after segmental resection and/or strictureplasty. (Tay GS, Binion DG, Eastwood D, Otterson MF) Surgery 2003 Oct;134(4):565-72; discussion 572-3 PMID: 14605616 11/08/2003
  • Sodium butyrate inhibits angiogenesis of human intestinal microvascular endothelial cells through COX-2 inhibition. (Ogawa H, Rafiee P, Fisher PJ, Johnson NA, Otterson MF, Binion DG) FEBS Lett 2003 Nov 6;554(1-2):88-94 PMID: 14596920 11/05/2003
  • Sequelae of cryotherapy in breast tissue. (Otterson MF, Redlich PN, McDonald A, Kristin Thorsen M, Klaas KK, Clowry LJ, Walker AP) Cryobiology 2003 Oct;47(2):174-8 PMID: 14580851 10/29/2003
  • Butyrate modulates gene and protein expression in human intestinal endothelial cells. (Ogawa H, Rafiee P, Fisher PJ, Johnson NA, Otterson MF, Binion DG) Biochem Biophys Res Commun 2003 Sep 26;309(3):512-9 PMID: 12963019 09/10/2003
  • Acquired microvascular dysfunction in inflammatory bowel disease: Loss of nitric oxide-mediated vasodilation. (Hatoum OA, Binion DG, Otterson MF, Gutterman DD) Gastroenterology 2003 Jul;125(1):58-69 PMID: 12851871 07/10/2003
  • Mechanisms of endotoxin tolerance in human intestinal microvascular endothelial cells. (Ogawa H, Rafiee P, Heidemann J, Fisher PJ, Johnson NA, Otterson MF, Kalyanaraman B, Pritchard KA Jr, Binion DG) J Immunol 2003 Jun 15;170(12):5956-64 PMID: 12794122 06/10/2003
  • Case report: magnetic resonance imaging in the diagnosis of epidural abscess complicating perirectal fistulizing Crohn's disease. (Heidemann J, Spinelli KS, Otterson MF, Binion DG) Inflamm Bowel Dis 2003 Mar;9(2):122-4 PMID: 12769446 05/29/2003
  • Angiogenic effects of interleukin 8 (CXCL8) in human intestinal microvascular endothelial cells are mediated by CXCR2. (Heidemann J, Ogawa H, Dwinell MB, Rafiee P, Maaser C, Gockel HR, Otterson MF, Ota DM, Lugering N, Domschke W, Binion DG) J Biol Chem 2003 Mar 7;278(10):8508-15 PMID: 12496258 12/24/2002
  • Effect of gender on endothelium-dependent dilation to bradykinin in human adipose microvessels. (Sato A, Miura H, Liu Y, Somberg LB, Otterson MF, Demeure MJ, Schulte WJ, Eberhardt LM, Loberiza FR, Sakuma I, Gutterman DD) Am J Physiol Heart Circ Physiol 2002 Sep;283(3):H845-52 PMID: 12181110 08/16/2002
  • Cyclosporine A enhances leukocyte binding by human intestinal microvascular endothelial cells through inhibition of p38 MAPK and iNOS. Paradoxical proinflammatory effect on the microvascular endothelium. (Rafiee P, Johnson CP, Li MS, Ogawa H, Heidemann J, Fisher PJ, Lamirand TH, Otterson MF, Wilson KT, Binion DG) J Biol Chem 2002 Sep 20;277(38):35605-15 PMID: 12110686 07/12/2002
  • Does breast tumor location influence success of sentinel lymph node biopsy? (Ahrendt GM, Laud P, Tjoe J, Eastwood D, Walker AP, Otterson MF, Redlich PN) J Am Coll Surg 2002 Mar;194(3):278-84 PMID: 11893131 03/15/2002
  • Deficient iNOS in inflammatory bowel disease intestinal microvascular endothelial cells results in increased leukocyte adhesion. (Binion DG, Rafiee P, Ramanujam KS, Fu S, Fisher PJ, Rivera MT, Johnson CP, Otterson MF, Telford GL, Wilson KT) Free Radic Biol Med 2000 Nov 1;29(9):881-8 PMID: 11063913 11/07/2000
  • Nitric oxide production is diminished in colonic circular muscle from acquired megacolon. (Koch TR, Otterson MF, Telford GL) Dis Colon Rectum 2000 Jun;43(6):821-8 PMID: 10859084 06/20/2000
  • Decreased vasoactive intestinal peptide levels and glutathione depletion in acquired megacolon. (Koch TR, Schulte-Bockholt A, Otterson MF, Telford GL, Stryker SJ, Ballard T, Opara EC) Dig Dis Sci 1996 Jul;41(7):1409-16 PMID: 8689918 07/01/1996
  • Multidisciplinary management of altered body image in the patient with an ostomy. (Walsh BA, Grunert BK, Telford GL, Otterson MF) J Wound Ostomy Continence Nurs 1995 Sep;22(5):227-36 PMID: 7550779 09/01/1995
  • Fractionated irradiation alters enteric neuroendocrine products. (Otterson MF, Koch TR, Zhang Z, Leming SC, Moulder JE) Dig Dis Sci 1995 Aug;40(8):1691-702 PMID: 7544259 08/01/1995
  • Expression of mRNA for vasoactive intestinal peptide in normal human colon and during inflammation. (Schulte-Bockholt A, Fink JG, Meier DA, Otterson MF, Telford GL, Hopp K, Koch TR) Mol Cell Biochem 1995 Jan 12;142(1):1-7 PMID: 7753037 01/12/1995
  • Chronic intestinal pseudo-obstruction. (Engelsgjerd M, Otterson MF, Condon RE) Adv Surg 1995;28:397-405 PMID: 7879688 01/01/1995
  • Neural control of small intestinal giant migrating contractions. (Otterson MF, Sarna SK) Am J Physiol 1994 Apr;266(4 Pt 1):G576-84 PMID: 8178996 04/01/1994
  • Altered motility causes the early gastrointestinal toxicity of irradiation. (Erickson BA, Otterson MF, Moulder JE, Sarna SK) Int J Radiat Oncol Biol Phys 1994 Mar 1;28(4):905-12 PMID: 8138444 03/01/1994
  • Gene expression and transcript size of the prepro-peptide VIP/PHM-27 in normal human tissue. (Schulte-Bockholt A, Meier DA, Hopp K, Stadelmann A, Otterson MF, Telford GL, Koch TR) Neurosci Lett 1993 Dec 24;164(1-2):101-4 PMID: 8152582 12/24/1993
  • Normal physiology of small intestinal motility. (Otterson MF, Sarr MG) Surg Clin North Am 1993 Dec;73(6):1173-92 PMID: 8248833 12/01/1993
  • Acquired megacolon is associated with alteration of vasoactive intestinal peptide levels and acetylcholinesterase activity. (Koch TR, Schulte-Bockholt A, Telford GL, Otterson MF, Murad TM, Stryker SJ) Regul Pept 1993 Nov 3;48(3):309-19 PMID: 7506433 11/03/1993
  • Nitric oxide regulates migrating motor complex cycling and its postprandial disruption. (Sarna SK, Otterson MF, Ryan RP, Cowles VE) Am J Physiol 1993 Oct;265(4 Pt 1):G749-66 PMID: 7694478 10/01/1993
  • Characterization of neuropeptides extracted from canine intestine. (Koch TR, Otterson MF, Roddy DR, Go VL) Neuropeptides 1993 Jun;24(6):359-65 PMID: 7688877 06/01/1993
  • Effects of fractionated doses of ionizing radiation on colonic motor activity. (Otterson MF, Sarna SK, Leming SC, Moulder JE, Fink JG) Am J Physiol 1992 Oct;263(4 Pt 1):G518-26 PMID: 1415710 10/01/1992
  • Fractionated doses of ionizing radiation alter postprandial small intestinal motor activity. (Otterson MF, Sarna SK, Lee MB) Dig Dis Sci 1992 May;37(5):709-15 PMID: 1563312 05/01/1992
  • Gastrointestinal motor effects of erythromycin. (Otterson MF, Sarna SK) Am J Physiol 1990 Sep;259(3 Pt 1):G355-63 PMID: 2399980 09/01/1990
  • Small intestinal amyogenesia and dysmyogenesia induced by morphine and loperamide. (Sarna SK, Otterson MF) Am J Physiol 1990 Feb;258(2 Pt 1):G282-9 PMID: 1968317 02/01/1990
  • Local effect of substance P on colonic motor activity in different experimental states. (Hou JY, Otterson MF, Sarna SK) Am J Physiol 1989 Jun;256(6 Pt 1):G997-1004 PMID: 2472074 06/01/1989
  • Small intestinal physiology and pathophysiology. (Sarna SK, Otterson MF) Gastroenterol Clin North Am 1989 Jun;18(2):375-404 PMID: 2668175 06/01/1989
  • Effects of fractionated doses of ionizing radiation on small intestinal motor activity. (Otterson MF, Sarna SK, Moulder JE) Gastroenterology 1988 Nov;95(5):1249-57 PMID: 3169493 11/01/1988
  • Gastrointestinal motility: some basic concepts. (Sarna SK, Otterson MF) Pharmacology 1988;36 Suppl 1:7-14 PMID: 3285364 01/01/1988
  • Last update: 09/21/2015
    jenkins-FCD Prod-29 84643b21e512b06ca32a9eea21e90ce5435f61b4