Medical College of Wisconsin
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Mary F. Otterson MD

Mary F. Otterson MD

Professor

Institution: Medical College of Wisconsin
Department: Surgery
Division: Colorectal Surgery
Program: Colorectal Surgery

Member of the Cancer Center


Publications

  • Propagation of giant migrating contractions between the small intestine, cecum and colon during radiation. (Otterson MF, Leming SC, Fox CJ, Moulder JE) Neurogastroenterol Motil 2010 Aug;22(8):919-26 PMID: 20529206
  • Animal models for medical countermeasures to radiation exposure. (Williams JP, Brown SL, Georges GE, Hauer-Jensen M, Hill RP, Huser AK, Kirsch DG, Macvittie TJ, Mason KA, Medhora MM, Moulder JE, Okunieff P, Otterson MF, Robbins ME, Smathers JB, McBride WH) Radiat Res 2010 Apr;173(4):557-78 PMID: 20334528 PMCID: PMC3021126
  • Modulatory effect of curcumin on survival of irradiated human intestinal microvascular endothelial cells: role of Akt/mTOR and NF-{kappa}B. (Rafiee P, Binion DG, Wellner M, Behmaram B, Floer M, Mitton E, Nie L, Zhang Z, Otterson MF) Am J Physiol Gastrointest Liver Physiol 2010 Jun;298(6):G865-77 PMID: 20299603 PMCID: PMC3774333
  • Chlorhexidine-Alcohol versus Povidone-Iodine for Surgical-Site Antisepsis. (Darouiche RO, Wall MJ Jr, Itani KM, Otterson MF, Webb AL, Carrick MM, Miller HJ, Awad SS, Crosby CT, Mosier MC, Alsharif A, Berger DH) N Engl J Med 2010 Jan 7;362(1):18-26 PMID: 20054046
  • Thalidomide inhibits inflammatory and angiogenic activation of human intestinal microvascular endothelial cells (HIMEC). (Rafiee P, Stein DJ, Nelson VM, Otterson MF, Shaker R, Binion DG) Am J Physiol Gastrointest Liver Physiol 2010 Feb;298(2):G167-76 PMID: 19926820 PMCID: PMC2822501
  • Impact of autonomic dysfunction on inflammatory bowel disease. (Ananthakrishnan AN, Issa M, Barboi A, Jaradeh S, Zadvornova Y, Skaros S, Johnson K, Otterson MF, Binion DG) J Clin Gastroenterol 2010 Apr;44(4):272-9 PMID: 19727003
  • Vascular cell adhesion molecule-1 expression in human intestinal microvascular endothelial cells is regulated by PI 3-kinase/Akt/MAPK/NF-kappaB: inhibitory role of curcumin. (Binion DG, Heidemann J, Li MS, Nelson VM, Otterson MF, Rafiee P) Am J Physiol Gastrointest Liver Physiol 2009 Aug;297(2):G259-68 PMID: 19520742 PMCID: PMC2724083
  • Durability of infliximab in Crohn's disease: a single-center experience. (Gonzaga JE, Ananthakrishnan AN, Issa M, Beaulieu DB, Skaros S, Zadvornova Y, Johnson K, Otterson MF, Binion DG) Inflamm Bowel Dis 2009 Dec;15(12):1837-43 PMID: 19462426
  • History of medical hospitalization predicts future need for colectomy in patients with ulcerative colitis. (Ananthakrishnan AN, Issa M, Beaulieu DB, Skaros S, Knox JF, Lemke K, Emmons J, Lundeen SH, Otterson MF, Binion DG) Inflamm Bowel Dis 2009 Feb;15(2):176-81 PMID: 18680197
  • Budesonide induction and maintenance therapy for Crohn's disease during pregnancy. (Beaulieu DB, Ananthakrishnan AN, Issa M, Rosenbaum L, Skaros S, Newcomer JR, Kuhlmann RS, Otterson MF, Emmons J, Knox J, Binion DG) Inflamm Bowel Dis 2009 Jan;15(1):25-8 PMID: 18680195
  • Role of MutS homolog 2 (MSH2) in intestinal myofibroblast proliferation during Crohn's disease stricture formation. (Floer M, Binion DG, Nelson VM, Manley S, Wellner M, Sadeghi S, Behmaram B, Sewell C, Otterson MF, Kucharzik T, Rafiee P) Am J Physiol Gastrointest Liver Physiol 2008 Sep;295(3):G581-90 PMID: 18635600 PMCID: PMC2536780
  • Curcumin inhibits VEGF-mediated angiogenesis in human intestinal microvascular endothelial cells through COX-2 and MAPK inhibition. (Binion DG, Otterson MF, Rafiee P) Gut 2008 Nov;57(11):1509-17 PMID: 18596194 PMCID: PMC2582343
  • Novel method for recolonoscopy after percutaneous cecostomy. (Berger WL, Kounev V, Otterson MF) Gastrointest Endosc 2008 May;67(6):1005-6 PMID: 18243187
  • Permanent work disability in Crohn's disease. (Ananthakrishnan AN, Weber LR, Knox JF, Skaros S, Emmons J, Lundeen S, Issa M, Otterson MF, Binion DG) Am J Gastroenterol 2008 Jan;103(1):154-61 PMID: 18076736
  • Clinical factors contributing to rapid reoperation for Crohn's disease patients undergoing resection and/or strictureplasty. (Binion DG, Theriot KR, Shidham S, Lundeen S, Hatoum O, Lim HJ, Otterson MF) J Gastrointest Surg 2007 Dec;11(12):1692-8; dicussion 1698 PMID: 17940830
  • Severe pulmonary toxicity after azathioprine/6-mercaptopurine initiation for the treatment of inflammatory bowel disease. (Ananthakrishnan AN, Attila T, Otterson MF, Lipchik RJ, Massey BT, Komorowski RA, Binion DG) J Clin Gastroenterol 2007 Aug;41(7):682-8 PMID: 17667053
  • Effects of radiation upon gastrointestinal motility. (Otterson MF) World J Gastroenterol 2007 May 21;13(19):2684-92 PMID: 17569136 PMCID: PMC4147116
  • Tissue and fluid penetration of garenoxacin in surgical patients. (Edmiston CE, Krepel CJ, Seabrook GR, Towne JB, Smith TL, Loehrl TA, Wackym PA, Johnson CP, Otterson MF, Gajjar DA, Krishna G) Surg Infect (Larchmt) 2007 Apr;8(2):179-88 PMID: 17437363
  • Clostridium difficile enteritis: an early postoperative complication in inflammatory bowel disease patients after colectomy. (Lundeen SJ, Otterson MF, Binion DG, Carman ET, Peppard WJ) J Gastrointest Surg 2007 Feb;11(2):138-42 PMID: 17390162
  • Impact of Clostridium difficile on inflammatory bowel disease. (Issa M, Vijayapal A, Graham MB, Beaulieu DB, Otterson MF, Lundeen S, Skaros S, Weber LR, Komorowski RA, Knox JF, Emmons J, Bajaj JS, Binion DG) Clin Gastroenterol Hepatol 2007 Mar;5(3):345-51 PMID: 17368234
  • Increased arginase activity and endothelial dysfunction in human inflammatory bowel disease. (Horowitz S, Binion DG, Nelson VM, Kanaa Y, Javadi P, Lazarova Z, Andrekopoulos C, Kalyanaraman B, Otterson MF, Rafiee P) Am J Physiol Gastrointest Liver Physiol 2007 May;292(5):G1323-36 PMID: 17218473
  • Radiation induces endothelial dysfunction in murine intestinal arterioles via enhanced production of reactive oxygen species. (Hatoum OA, Otterson MF, Kopelman D, Miura H, Sukhotnik I, Larsen BT, Selle RM, Moulder JE, Gutterman DD) Arterioscler Thromb Vasc Biol 2006 Feb;26(2):287-94 PMID: 16322529
  • Novel mechanism of vasodilation in inflammatory bowel disease. (Hatoum OA, Gauthier KM, Binion DG, Miura H, Telford G, Otterson MF, Campbell WB, Gutterman DD) Arterioscler Thromb Vasc Biol 2005 Nov;25(11):2355-61 PMID: 16141408
  • Radiation induced small bowel "web" formation is associated with acquired microvascular dysfunction. (Hatoum OA, Binion DG, Phillips SA, O'Loughlin C, Komorowski RA, Gutterman DD, Otterson MF) Gut 2005 Dec;54(12):1797-800 PMID: 16127018 PMCID: PMC1774807
  • Transrectal and transvaginal sonographic intervention of infected pelvic fluid collections: a complete approach. (Sudakoff GS, Lundeen SJ, Otterson MF) Ultrasound Q 2005 Sep;21(3):175-85 PMID: 16096614
  • Mesenteric venous thrombosis in inflammatory bowel disease. (Hatoum OA, Spinelli KS, Abu-Hajir M, Attila T, Franco J, Otterson MF, Telford GL, Binion DG) J Clin Gastroenterol 2005 Jan;39(1):27-31 PMID: 15599206
  • Mechanisms of MAdCAM-1 gene expression in human intestinal microvascular endothelial cells. (Ogawa H, Binion DG, Heidemann J, Theriot M, Fisher PJ, Johnson NA, Otterson MF, Rafiee P) Am J Physiol Cell Physiol 2005 Feb;288(2):C272-81 PMID: 15483224
  • Radiographic underestimation of small bowel stricturing Crohn's disease: a comparison with surgical findings. (Otterson MF, Lundeen SJ, Spinelli KS, Sudakoff GS, Telford GL, Hatoum OA, Saeian K, Yun H, Binion DG) Surgery 2004 Oct;136(4):854-60 PMID: 15467672
  • Role of hydrogen peroxide in ACh-induced dilation of human submucosal intestinal microvessels. (Hatoum OA, Binion DG, Miura H, Telford G, Otterson MF, Gutterman DD) Am J Physiol Heart Circ Physiol 2005 Jan;288(1):H48-54 PMID: 15345486
  • Cyclosporin A differentially inhibits multiple steps in VEGF induced angiogenesis in human microvascular endothelial cells through altered intracellular signaling. (Rafiee P, Heidemann J, Ogawa H, Johnson NA, Fisher PJ, Li MS, Otterson MF, Johnson CP, Binion DG) Cell Commun Signal 2004 Jun 2;2(1):3 PMID: 15175101 PMCID: PMC441414
  • Antiangiogenic treatment of mesenteric desmoid tumors with toremifene and interferon alfa-2b: report of two cases. (Heidemann J, Ogawa H, Otterson MF, Shidham VB, Binion DG) Dis Colon Rectum 2004 Jan;47(1):118-22 PMID: 14719159
  • Multivariate analysis suggests improved perioperative outcome in Crohn's disease patients receiving immunomodulator therapy after segmental resection and/or strictureplasty. (Tay GS, Binion DG, Eastwood D, Otterson MF) Surgery 2003 Oct;134(4):565-72; discussion 572-3 PMID: 14605616
  • Sodium butyrate inhibits angiogenesis of human intestinal microvascular endothelial cells through COX-2 inhibition. (Ogawa H, Rafiee P, Fisher PJ, Johnson NA, Otterson MF, Binion DG) FEBS Lett 2003 Nov 6;554(1-2):88-94 PMID: 14596920
  • Sequelae of cryotherapy in breast tissue. (Otterson MF, Redlich PN, McDonald A, Kristin Thorsen M, Klaas KK, Clowry LJ, Walker AP) Cryobiology 2003 Oct;47(2):174-8 PMID: 14580851
  • Butyrate modulates gene and protein expression in human intestinal endothelial cells. (Ogawa H, Rafiee P, Fisher PJ, Johnson NA, Otterson MF, Binion DG) Biochem Biophys Res Commun 2003 Sep 26;309(3):512-9 PMID: 12963019
  • Acquired microvascular dysfunction in inflammatory bowel disease: Loss of nitric oxide-mediated vasodilation. (Hatoum OA, Binion DG, Otterson MF, Gutterman DD) Gastroenterology 2003 Jul;125(1):58-69 PMID: 12851871
  • Mechanisms of endotoxin tolerance in human intestinal microvascular endothelial cells. (Ogawa H, Rafiee P, Heidemann J, Fisher PJ, Johnson NA, Otterson MF, Kalyanaraman B, Pritchard KA Jr, Binion DG) J Immunol 2003 Jun 15;170(12):5956-64 PMID: 12794122
  • Case report: magnetic resonance imaging in the diagnosis of epidural abscess complicating perirectal fistulizing Crohn's disease. (Heidemann J, Spinelli KS, Otterson MF, Binion DG) Inflamm Bowel Dis 2003 Mar;9(2):122-4 PMID: 12769446
  • Angiogenic effects of interleukin 8 (CXCL8) in human intestinal microvascular endothelial cells are mediated by CXCR2. (Heidemann J, Ogawa H, Dwinell MB, Rafiee P, Maaser C, Gockel HR, Otterson MF, Ota DM, Lugering N, Domschke W, Binion DG) J Biol Chem 2003 Mar 7;278(10):8508-15 PMID: 12496258
  • Effect of gender on endothelium-dependent dilation to bradykinin in human adipose microvessels. (Sato A, Miura H, Liu Y, Somberg LB, Otterson MF, Demeure MJ, Schulte WJ, Eberhardt LM, Loberiza FR, Sakuma I, Gutterman DD) Am J Physiol Heart Circ Physiol 2002 Sep;283(3):H845-52 PMID: 12181110
  • Cyclosporine A enhances leukocyte binding by human intestinal microvascular endothelial cells through inhibition of p38 MAPK and iNOS. Paradoxical proinflammatory effect on the microvascular endothelium. (Rafiee P, Johnson CP, Li MS, Ogawa H, Heidemann J, Fisher PJ, Lamirand TH, Otterson MF, Wilson KT, Binion DG) J Biol Chem 2002 Sep 20;277(38):35605-15 PMID: 12110686
  • Does breast tumor location influence success of sentinel lymph node biopsy? (Ahrendt GM, Laud P, Tjoe J, Eastwood D, Walker AP, Otterson MF, Redlich PN) J Am Coll Surg 2002 Mar;194(3):278-84 PMID: 11893131
  • Deficient iNOS in inflammatory bowel disease intestinal microvascular endothelial cells results in increased leukocyte adhesion. (Binion DG, Rafiee P, Ramanujam KS, Fu S, Fisher PJ, Rivera MT, Johnson CP, Otterson MF, Telford GL, Wilson KT) Free Radic Biol Med 2000 Nov 1;29(9):881-8 PMID: 11063913
  • Nitric oxide production is diminished in colonic circular muscle from acquired megacolon. (Koch TR, Otterson MF, Telford GL) Dis Colon Rectum 2000 Jun;43(6):821-8 PMID: 10859084
  • Decreased vasoactive intestinal peptide levels and glutathione depletion in acquired megacolon. (Koch TR, Schulte-Bockholt A, Otterson MF, Telford GL, Stryker SJ, Ballard T, Opara EC) Dig Dis Sci 1996 Jul;41(7):1409-16 PMID: 8689918
  • Multidisciplinary management of altered body image in the patient with an ostomy. (Walsh BA, Grunert BK, Telford GL, Otterson MF) J Wound Ostomy Continence Nurs 1995 Sep;22(5):227-36 PMID: 7550779
  • Fractionated irradiation alters enteric neuroendocrine products. (Otterson MF, Koch TR, Zhang Z, Leming SC, Moulder JE) Dig Dis Sci 1995 Aug;40(8):1691-702 PMID: 7544259
  • Expression of mRNA for vasoactive intestinal peptide in normal human colon and during inflammation. (Schulte-Bockholt A, Fink JG, Meier DA, Otterson MF, Telford GL, Hopp K, Koch TR) Mol Cell Biochem 1995 Jan 12;142(1):1-7 PMID: 7753037
  • Chronic intestinal pseudo-obstruction. (Engelsgjerd M, Otterson MF, Condon RE) Adv Surg 1995;28:397-405 PMID: 7879688
  • Neural control of small intestinal giant migrating contractions. (Otterson MF, Sarna SK) Am J Physiol 1994 Apr;266(4 Pt 1):G576-84 PMID: 8178996
  • Altered motility causes the early gastrointestinal toxicity of irradiation. (Erickson BA, Otterson MF, Moulder JE, Sarna SK) Int J Radiat Oncol Biol Phys 1994 Mar 1;28(4):905-12 PMID: 8138444
  • Gene expression and transcript size of the prepro-peptide VIP/PHM-27 in normal human tissue. (Schulte-Bockholt A, Meier DA, Hopp K, Stadelmann A, Otterson MF, Telford GL, Koch TR) Neurosci Lett 1993 Dec 24;164(1-2):101-4 PMID: 8152582
  • Normal physiology of small intestinal motility. (Otterson MF, Sarr MG) Surg Clin North Am 1993 Dec;73(6):1173-92 PMID: 8248833
  • Acquired megacolon is associated with alteration of vasoactive intestinal peptide levels and acetylcholinesterase activity. (Koch TR, Schulte-Bockholt A, Telford GL, Otterson MF, Murad TM, Stryker SJ) Regul Pept 1993 Nov 3;48(3):309-19 PMID: 7506433
  • Nitric oxide regulates migrating motor complex cycling and its postprandial disruption. (Sarna SK, Otterson MF, Ryan RP, Cowles VE) Am J Physiol 1993 Oct;265(4 Pt 1):G749-66 PMID: 7694478
  • Characterization of neuropeptides extracted from canine intestine. (Koch TR, Otterson MF, Roddy DR, Go VL) Neuropeptides 1993 Jun;24(6):359-65 PMID: 7688877
  • Effects of fractionated doses of ionizing radiation on colonic motor activity. (Otterson MF, Sarna SK, Leming SC, Moulder JE, Fink JG) Am J Physiol 1992 Oct;263(4 Pt 1):G518-26 PMID: 1415710
  • Fractionated doses of ionizing radiation alter postprandial small intestinal motor activity. (Otterson MF, Sarna SK, Lee MB) Dig Dis Sci 1992 May;37(5):709-15 PMID: 1563312
  • Gastrointestinal motor effects of erythromycin. (Otterson MF, Sarna SK) Am J Physiol 1990 Sep;259(3 Pt 1):G355-63 PMID: 2399980
  • Small intestinal amyogenesia and dysmyogenesia induced by morphine and loperamide. (Sarna SK, Otterson MF) Am J Physiol 1990 Feb;258(2 Pt 1):G282-9 PMID: 1968317
  • Local effect of substance P on colonic motor activity in different experimental states. (Hou JY, Otterson MF, Sarna SK) Am J Physiol 1989 Jun;256(6 Pt 1):G997-1004 PMID: 2472074
  • Small intestinal physiology and pathophysiology. (Sarna SK, Otterson MF) Gastroenterol Clin North Am 1989 Jun;18(2):375-404 PMID: 2668175
  • Effects of fractionated doses of ionizing radiation on small intestinal motor activity. (Otterson MF, Sarna SK, Moulder JE) Gastroenterology 1988 Nov;95(5):1249-57 PMID: 3169493
  • Gastrointestinal motility: some basic concepts. (Sarna SK, Otterson MF) Pharmacology 1988;36 Suppl 1:7-14 PMID: 3285364
  • Last update: 12/13/2011